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1. Biomedical articles (top 50; 2010 to 2015)
1. Vano-Galvan S, Martorell A: Chilblains. CMAJ; 2012 Jan 10;184(1):67
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains.
  • [MeSH-major] Chilblains / diagnosis. Foot Dermatoses / complications
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Follow-Up Studies. Humans

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  • [Cites] Ann Dermatol Venereol. 2001 Apr;128(4):557-60 [11395660.001]
  • [Cites] J Am Acad Dermatol. 2010 Jun;62(6):e21-2 [20466166.001]
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  • [Cites] Br J Dermatol. 1989 Feb;120(2):267-75 [2647123.001]
  • (PMID = 22025653.001).
  • [ISSN] 1488-2329
  • [Journal-full-title] CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • [ISO-abbreviation] CMAJ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3255185
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2. Vano-Galvan S, Moreno C, Fernández-Lorente M, Jaén P: Classic Kaposi sarcoma mimicking chilblains. Dermatol Online J; 2011;17(2):16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Classic Kaposi sarcoma mimicking chilblains.
  • We report a case of classic KS mimicking chilblains.
  • [MeSH-major] Chilblains / pathology. Sarcoma, Kaposi / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Doxorubicin / therapeutic use. Humans. Male


3. Tonoli RE, Souza PR: Case for diagnosis. Chilblains. An Bras Dermatol; 2012 Jul-Aug;87(4):649-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case for diagnosis. Chilblains.
  • Chilblains are an inflammatory skin condition that develops following exposure to the cold.
  • They consist of pruritic and/or painful erythematous-to-violaceous acral lesions and are the result of an abnormal vascular response to exposure to the cold.
  • [MeSH-major] Chilblains / diagnosis. Hand Dermatoses / diagnosis

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  • (PMID = 22892789.001).
  • [ISSN] 1806-4841
  • [Journal-full-title] Anais brasileiros de dermatologia
  • [ISO-abbreviation] An Bras Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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4. Akkurt ZM, Ucmak D, Yildiz K, Yürüker SK, Celik HÖ: Chilblains in Turkey: a case-control study. An Bras Dermatol; 2014 Jan-Feb;89(1):44-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains in Turkey: a case-control study.
  • BACKGROUND: Chilblains are rather common in winter months in our country.
  • OBJECTIVES: Determination of demographical and clinical characteristics of patients presenting with chilblains in Diyarbakir, Turkey.
  • Evaluation of body mass index (BMI) as risk factor for development of chilblains.
  • METHODS: Sixty-nine patients who were diagnosed as chilblains at our outpatient clinics were included in this study.
  • RESULTS: Of the 69 patients with chilblains, 45 (65.2%) were females and 24 (34.8%) were males.
  • 61.3% of the patients reported recurrence of the lesions every winter season.
  • CONCLUSIONS: Low BMI may be a risk factor contributing to development of chilblains in persons exposed to cold weather conditions.
  • Diagnosis of chilblains requires wariness, as history of cold exposure may not be evident.
  • [MeSH-major] Body Mass Index. Chilblains / etiology

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  • [Cites] Clin Physiol. 2000 Sep;20(5):360-5 [10971547.001]
  • [Cites] Wilderness Environ Med. 2010 Mar;21(1):17-21.e1 [20591349.001]
  • [Cites] Eur J Appl Physiol. 2003 Jun;89(5):411-26 [12712346.001]
  • [Cites] Pediatr Dermatol. 1994 Mar;11(1):1-5 [8170840.001]
  • [Cites] Cutis. 1994 Dec;54(6):395-9 [7867381.001]
  • [Cites] Pediatrics. 2005 Sep;116(3):e472-5 [16140694.001]
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  • [Cites] Clin Rheumatol. 2008 Aug;27(8):949-54 [18543054.001]
  • [Cites] Acta Derm Venereol. 2010 Sep;90(5):544-5 [20814645.001]
  • [Cites] Br J Dermatol. 2010 Sep;163(3):645-6 [20426783.001]
  • [Cites] Microcirculation. 2012 Jan;19(1):65-77 [21851473.001]
  • [Cites] CMAJ. 2012 Jan 10;184(1):67 [22025653.001]
  • [Cites] An Bras Dermatol. 2012 Jul-Aug;87(4):649-50 [22892789.001]
  • [Cites] Dermatol Surg. 2012 Sep;38(9):1555-6 [22691068.001]
  • [Cites] Clin Exp Dermatol. 2012 Dec;37(8):844-9 [23082992.001]
  • [Cites] Eur J Appl Physiol. 2010 May;109(1):133-40 [20135142.001]
  • [Cites] J Am Acad Dermatol. 2010 Jun;62(6):e21-2 [20466166.001]
  • [Cites] Arch Dis Child. 2010 Jul;95(7):567-8 [20522476.001]
  • [Cites] Medicine (Baltimore). 2001 May;80(3):180-8 [11388094.001]
  • (PMID = 24626647.001).
  • [ISSN] 1806-4841
  • [Journal-full-title] Anais brasileiros de dermatologia
  • [ISO-abbreviation] An Bras Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC3938353
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5. 'Chilblains Disorder': Top Publications. BioMedLib Review OC; ;ChilblainsDisorder:709920688. ISSN: 2331-5717. 2015/11/10; updates online.
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  • [Title] 'Chilblains Disorder': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblains disorder'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920688.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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6. Kanazawa N: Nakajo-Nishimura syndrome: an autoinflammatory disorder showing pernio-like rashes and progressive partial lipodystrophy. Allergol Int; 2012 Jun;61(2):197-206
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nakajo-Nishimura syndrome: an autoinflammatory disorder showing pernio-like rashes and progressive partial lipodystrophy.
  • Nakajo-Nishimura syndrome (ORPHA2615; also registered as Nakajo syndrome in OMIM#256040) is a distinct inherited inflammatory and wasting disease, originally reported from Japan.
  • This disease usually begins in early infancy with a pernio-like rash, especially in winter.
  • The patients develop periodic high fever and nodular erythema-like eruptions, and gradually progress lipomuscular atrophy in the upper body, mainly the face and the upper extremities, to show the characteristic thin facial appearance and long clubbed fingers with joint contractures.
  • Although cause of the disease has long been undefined, a homozygous mutation of the PSMB8 gene, which encodes the β5i subunit of immunoproteasome, has been identified to be responsible in 2011.
  • [MeSH-major] Chilblains / immunology. Erythema Nodosum / immunology. Exanthema / immunology. Lipodystrophy / immunology. Proteasome Endopeptidase Complex / metabolism


7. Fye JM, Orebaugh CD, Coffin SR, Hollis T, Perrino FW: Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome. J Biol Chem; 2011 Sep 16;286(37):32373-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • TREX1 mutations at amino acid positions Asp-18 and Asp-200 in familial chilblain lupus and Aicardi-Goutières syndrome elicit dominant immune dysfunction phenotypes.
  • Thus, the dominant disease genetics exhibited by the TREX1 D18N, D200N, and D200H alleles parallel precisely the biochemical properties of these TREX1 dimers during dsDNA degradation of plasmid and chromatin DNA in vitro.
  • These results support the concept that failure to degrade genomic dsDNA is a principal pathway of immune activation in TREX1-mediated autoimmune disease.
  • [MeSH-major] Autoimmune Diseases of the Nervous System / enzymology. Chilblains / enzymology. DNA, Single-Stranded / metabolism. Exodeoxyribonucleases / metabolism. Genes, Dominant. Lupus Erythematosus, Cutaneous / enzymology. Mutation, Missense. Nervous System Malformations / enzymology. Phosphoproteins / metabolism


8. Gordon R, Arikian AM, Pakula AS: Chilblains in Southern California: two case reports and a review of the literature. J Med Case Rep; 2014;8:381
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains in Southern California: two case reports and a review of the literature.
  • INTRODUCTION: Chilblains or perniosis is an acrally located cutaneous eruption that occurs with exposure to cold.
  • Chilblains can be classified into primary and secondary forms.
  • The primary or idiopathic form is not associated with an underlying disease and is clinically indistinguishable from the secondary form.
  • The secondary form is associated with an underlying condition such as connective tissue disease, monoclonal gammopathy, cryoglobulinemia, or chronic myelomonocytic leukemia.
  • Histopathology cannot accurately help distinguish the primary from secondary forms of chilblains.
  • This article will raise the awareness of chilblains by presenting two unusual case reports of chilblains in men from Southern California with discussion of the appropriate evaluation and treatment of this condition.
  • He had no unusual cold exposure prior to the onset of his symptoms.
  • CONCLUSIONS: Chilblains is a relatively uncommon entity in warmer climates but can present during the winter months.
  • It can be diagnosed clinically by the appearance of typical lesions during the cold damp season.
  • Through a thorough history, physical examination and selected laboratory evaluation, underlying connective tissue disease or a mimic such as vasculitis or cutaneous leukemia can be excluded.

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  • [Cites] Clin Rheumatol. 2008 Aug;27(8):949-54 [18543054.001]
  • [Cites] Am J Med. 2009 Dec;122(12):1152-5 [19958897.001]
  • [Cites] Eur J Dermatol. 2010 Nov-Dec;20(6):836-7 [21047722.001]
  • [Cites] Clin Rheumatol. 2012 Mar;31(3):563-8 [22207249.001]
  • [Cites] Arch Dermatol. 2012 Sep;148(9):1101-2 [22986885.001]
  • [Cites] Clin Exp Dermatol. 2012 Dec;37(8):844-9 [23082992.001]
  • [Cites] J Invest Dermatol. 2012 Dec;132(12):2855-7 [22718116.001]
  • [Cites] Rheumatology (Oxford). 2013 Feb;52(2):406-8 [22829693.001]
  • [Cites] J Am Acad Dermatol. 2001 Dec;45(6):924-9 [11712041.001]
  • [Cites] Br Med J (Clin Res Ed). 1986 Oct 11;293(6552):923-4 [3094717.001]
  • [Cites] J Am Acad Dermatol. 1990 Aug;23(2 Pt 1):257-62 [2212122.001]
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  • [Cites] J Rheumatol. 2005 Apr;32(4):760-1 [15801042.001]
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  • [Cites] Dermatology. 2009;219(2):162-6 [19478477.001]
  • (PMID = 25416648.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4275761
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9. 'Chilblains Eczema': Top Publications. BioMedLib Review CN; ;ChilblainsEczema:709664126. ISSN: 2331-5717. 2015/1/7; updates online.
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  • [Title] 'Chilblains Eczema': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblains eczema'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 5 publications.
  • Here are the top 3.
  • Weber FP: Note on Idiosyncrasies and Abnormalities in Human Beings.
  • Yang AY et al: Equestrian chilblain: another outdoor recreational hazard.
  • Sharma J et al: Ethnomedicinal plants used to treat skin diseases by Tharu community of district Udham Singh Nagar, Uttarakhand, India.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709664126.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review CN
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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10. Souwer IH, Lagro-Janssen AL: Chronic chilblains. BMJ; 2011;342:d2708
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic chilblains.
  • [MeSH-major] Chilblains / diagnosis
  • [MeSH-minor] Chronic Disease. Diagnosis, Differential. Female. Humans

  • ResearchGate. author profiles.
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  • (PMID = 21652748.001).
  • [ISSN] 1756-1833
  • [Journal-full-title] BMJ (Clinical research ed.)
  • [ISO-abbreviation] BMJ
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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11. Hermanns JF, Caucanas M, Piérard GE, Piérard-Franchimont C, Quatresooz P: [Chilblains, differential diagnosis and risk factors]. Rev Med Liege; 2010 Dec;65(12):688-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Chilblains, differential diagnosis and risk factors].
  • [Transliterated title] Les engelures, stigmates des affres climatiques.
  • Chilblain results from environmental nonfreezing cold exposure.
  • Chilblains are often idiopathic, but they may be part of lupus erythematosus.
  • [MeSH-major] Chilblains / diagnosis
  • [MeSH-minor] Cold Temperature / adverse effects. Diagnosis, Differential. Humans. Risk Factors

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  • (PMID = 21287764.001).
  • [ISSN] 0370-629X
  • [Journal-full-title] Revue médicale de Liège
  • [ISO-abbreviation] Rev Med Liege
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Belgium
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12. Prindaville B, Antaya RJ: Chilblains and microgeodic disease diagnosed concurrently in a child's toe. Pediatr Dermatol; 2013 Mar-Apr;30(2):269-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains and microgeodic disease diagnosed concurrently in a child's toe.
  • Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges.
  • Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed on skin biopsy.
  • This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging.
  • [MeSH-major] Chilblains / diagnosis. Finger Phalanges / pathology. Toes / pathology
  • [MeSH-minor] Child. Connecticut. Diagnosis, Differential. Humans. Male

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  • [Copyright] © 2012 Wiley Periodicals, Inc.
  • (PMID = 22277090.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Abdel-Salam GM, El-Kamah GY, Rice GI, El-Darouti M, Gornall H, Szynkiewicz M, Aymard F, Zaki MS, Abdel-Aleem AK, Lebon P, Crow YJ: Chilblains as a diagnostic sign of aicardi-goutières syndrome. Neuropediatrics; 2010 Feb;41(1):18-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains as a diagnostic sign of aicardi-goutières syndrome.
  • Aicardi-Goutières syndrome (AGS) is a genetically heterogeneous disorder showing variability in age of onset and clinical features.
  • Chilblain lesions have been described in AGS patients and recent papers have discussed the clinical, molecular and cutaneous histopathological overlap with chilblain lupus.
  • Here we report on 2 unrelated children with AGS and chilblain lesions, whose clinical histories and examination findings well illustrate the wide phenotypic variability that can be seen in this pleiotropic disorder.
  • Although both patients show remarkable similarity in the histopathology of their associated skin lesions, with thrombi formation, fat necrosis and hyalinization of the subcutaneous tissue, we note that the histopathology reported in other AGS cases with chilblains does not necessarily demonstrate this same uniformity.
  • Our findings highlight the significant role of the characteristic chilblain skin lesions in the diagnosis of AGS, and variability in the associated histopathology which may relate to the stage and severity of the disease.
  • [MeSH-major] Basal Ganglia Diseases / complications. Basal Ganglia Diseases / diagnosis. Chilblains / etiology. Eye Diseases / complications. Lupus Erythematosus, Systemic / complications


14. 'Chilblains Diagnosis': Top Publications. BioMedLib Review OC; ;ChilblainsDiagnosis:709920617. ISSN: 2331-5717. 2015/2/10; updates online.
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  • [Title] 'Chilblains Diagnosis': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblains diagnosis'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920617.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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15. 'Chilblains Disease Finding': Top Publications. BioMedLib Review OC; ;ChilblainsDiseaseFinding:709920609. ISSN: 2331-5717. 2015/9/10; updates online.
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  • [Title] 'Chilblains Disease Finding': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblains disease finding'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920609.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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16. 'Effects Of Chilblains': Top Publications. BioMedLib Review OC; ;EffectsOfChilblains:709920432. ISSN: 2331-5717. 2015/6/10; updates online.
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Effects Of Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'effects of chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920432.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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17. Cooper IF, Siadaty MS: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; Hormone;AdverseEffectCold:705148401. ISSN: 2331-5717. 2014/1/24
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  • [Title] 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Hormone' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Hormone'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 21 publications, and group two 285 publications.
  • Here are the top 10.
  • Khachemoune A: Papules and plaques on the nose. Lupus pernio.
  • Weismann K et al: Pernio of the hips in young girls wearing tight-fitting jeans with a low waistband.
  • Sugiura K et al: Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.
  • Price RD et al: Perniosis (chilblains) of the thigh: report of five cases, including four following river crossings.
  • Stewart CL et al: Equestrian perniosis: a report of 2 cases and a review of the literature.
  • Li Z: Thermotherapy: a novel possible treatment strategy of chronic rhinosinusitis based on the chilblain-like alteration in the early pathophysiology.
  • Souwer IH et al: Chilblains from the patient's perspective.
  • Viguier M et al: Clinical and histopathologic features and immunologic variables in patients with severe chilblains. A study of the relationship to lupus erythematosus.
  • Payne-James JJ et al: Pseudosclerodermatous triad of perniosis, pulp atrophy and 'parrot-beaked' clawing of the nails--a newly recognized syndrome of chronic crack cocaine use.
  • Giusti R et al: Picture of the month. Chilblains (pernio).

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705148401.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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18. Cooper IF, Siadaty MS: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; TherapeuticOrPreventive;AdverseEffectCold:705005080. ISSN: 2331-5717. 2014/10/22
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  • [Title] 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Therapeutic or Preventive Procedure' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Therapeutic or Preventive Procedure'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 19 publications, and group two 372 publications.
  • Here are the top 10.
  • Dowd PM et al: Nifedipine in the treatment of chilblains.
  • Simmons HJ: Treatment of Chilblains by Paravertebral Sympathetic Block.
  • Xiang F et al: [Clinical observation on 136 cases of chilblains treated by acupuncture combined with massage].
  • Young HS et al: CO2 laser vaporization for disfiguring lupus pernio.
  • THOMAS EW: CHAPPING AND CHILBLAINS.
  • Langtry JA et al: A double-blind study of ultraviolet phototherapy in the prophylaxis of chilblains.
  • Thomas EW: Chapping and chilblains.
  • Li Z: Thermotherapy: a novel possible treatment strategy of chronic rhinosinusitis based on the chilblain-like alteration in the early pathophysiology.
  • Aoki T et al: Chilblain lupus erythematosus of Hutchinson responding to surgical treatment: a report of two patients with anti-Ro/SS-A antibodies.
  • Verma P et al: Perniosis in an infant treated with topical nitroglycerine.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705005080.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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19. 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review OC; ;AdverseEffectCold:709920564. ISSN: 2331-5717. 2015/8/10; updates online.
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920564.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


20. Cooper IF, Siadaty MS: 'Organic Chemicals' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; OrganicChemical;AdverseEffectCold:706092552. ISSN: 2331-5717. 2014/1/22
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Organic Chemicals' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Organic Chemical' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Organic Chemical'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 19 publications, and group two 339 publications.
  • Here are the top 10.
  • Patra AK et al: Diltiazem vs. nifedipine in chilblains: a clinical trial.
  • Dowd PM et al: Nifedipine in the treatment of chilblains.
  • WHEATLEY DP: Vitamin K for the relief of chilblains.
  • : TREATMENT of chilblains by phenoxybenzamine; a clinical trial in general practice by the South-East Scotland Faculty of the College of General Practitioners.
  • Payne-James JJ et al: Pseudosclerodermatous triad of perniosis, pulp atrophy and 'parrot-beaked' clawing of the nails--a newly recognized syndrome of chronic crack cocaine use.
  • Yang X et al: Successful treatment of perniosis with hydroxychloroquine.
  • : Thymoxamine in chilblains.
  • Noaimi AA et al: Treatment of perniosis with oral pentoxyfylline in comparison with oral prednisolone plus topical clobetasol ointment in Iraqi patients.
  • Rustin MH et al: The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial.
  • Jaffe GV et al: Thymoxamine for Raynaud's disease and chilblains.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706092552.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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21. Cooper IF, Siadaty MS: 'Pharmacologic Substances' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; PharmacologicSubstance;AdverseEffectCold:706177220. ISSN: 2331-5717. 2014/4/23
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  • [Title] 'Pharmacologic Substances' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Pharmacologic Substance' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Pharmacologic Substance'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 20 publications, and group two 347 publications.
  • Here are the top 10.
  • Patra AK et al: Diltiazem vs. nifedipine in chilblains: a clinical trial.
  • Sugiura K et al: Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.
  • Dowd PM et al: Nifedipine in the treatment of chilblains.
  • Richez C et al: Infliximab induced chilblain lupus in a patient with rheumatoid arthritis.
  • Yang X et al: Successful treatment of perniosis with hydroxychloroquine.
  • Noaimi AA et al: Treatment of perniosis with oral pentoxyfylline in comparison with oral prednisolone plus topical clobetasol ointment in Iraqi patients.
  • Rustin MH et al: The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial.
  • Haley H et al: Infliximab therapy for sarcoidosis (lupus pernio).
  • Jaffe GV et al: Thymoxamine for Raynaud's disease and chilblains.
  • Souwer IH et al: Vitamin D3 is not effective in the treatment of chronic chilblains.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706177220.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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22. Cooper IF, Siadaty MS: 'Findings' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; Finding;AdverseEffectCold:706082356. ISSN: 2331-5717. 2014/11/22
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  • [Title] 'Findings' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Finding' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Finding'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 19 publications, and group two 451 publications.
  • Here are the top 10.
  • Rustin MH et al: Anorexia nervosa associated with acromegaloid features, onset of acrocyanosis and Raynaud's phenomenon and worsening of chilblains.
  • Spittell JA Jr et al: Chronic pernio: another cause of blue toes.
  • Young HS et al: CO2 laser vaporization for disfiguring lupus pernio.
  • Prindaville B et al: Chilblains and microgeodic disease diagnosed concurrently in a child's toe.
  • Larkins N et al: Major cluster of chilblain cases in a cold dry Western Australian winter.
  • El Sayed MJ: Perniosis: a case of painful progressive rash over the distal extremities.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Hwang JI et al: Postinflammatory melanonychia due to chilblain.
  • Helm TN et al: Chilblain lupus erythematosus lesions precipitated by the cold.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706082356.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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23. Cooper IF, Siadaty MS: 'Diseases or Syndromes' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; DiseaseOrSyndrome;AdverseEffectCold:706176857. ISSN: 2331-5717. 2014/10/23
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  • [Title] 'Diseases or Syndromes' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Disease or Syndrome' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Disease or Syndrome'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 27 publications, and group two 54 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Steroids' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Anjaneyan G et al: Lupus pernio without systemic involvement.
  • Patel S et al: Chilblain lupus erythematosus.
  • Shah A et al: Lupus pernio--a patient case study.
  • Yang AY et al: Equestrian chilblain: another outdoor recreational hazard.
  • Larkins N et al: Major cluster of chilblain cases in a cold dry Western Australian winter.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Gomes MM et al: Perniosis.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706176857.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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24. Cooper IF, Siadaty MS: 'Temporal Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; TemporalConcept;AdverseEffectCold:706094085. ISSN: 2331-5717. 2014/9/22
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Temporal Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Temporal Concept' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Temporal Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 15 publications, and group two 416 publications.
  • Here are the top 9.
  • Weismann K et al: Pernio of the hips in young girls wearing tight-fitting jeans with a low waistband.
  • Klapman MH et al: Localized recurrent postoperative pernio associated with leukocytoclastic vasculitis.
  • Rustin MH et al: The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial.
  • Stagaki E et al: The treatment of lupus pernio: results of 116 treatment courses in 54 patients.
  • Li Z: Thermotherapy: a novel possible treatment strategy of chronic rhinosinusitis based on the chilblain-like alteration in the early pathophysiology.
  • Larkins N et al: Major cluster of chilblain cases in a cold dry Western Australian winter.
  • Morioka N et al: [Evaluation of the past history of chilblain in cases of systemic lupus erythematosus (SLE) and its similar diseases].
  • Lewis FM et al: Lupus pernio following facial trauma.
  • Price RD et al: Perniosis (chilblains) of the thigh: report of five cases, including four following river crossings.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706094085.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


25. Cooper IF, Siadaty MS: 'Qualitative Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; QualitativeConcept;AdverseEffectCold:707323987. ISSN: 2331-5717. 2014/6/8
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  • [Title] 'Qualitative Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Qualitative Concept' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Qualitative Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 39 publications, and group two 279 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Findings' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Raza N et al: Onset of chilblains in relation with weather conditions.
  • Yanardag H et al: Lupus pernio in sarcoidosis: clinical features and treatment outcomes of 14 patients.
  • Larkins N et al: Major cluster of chilblain cases in a cold dry Western Australian winter.
  • Helm TN et al: Chilblain lupus erythematosus lesions precipitated by the cold.
  • Guadagni M et al: Acute perniosis in elderly people: a predictive sign of systemic disease?.
  • Sugiura K et al: Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.
  • Xiang F et al: [Clinical observation on 136 cases of chilblains treated by acupuncture combined with massage].
  • Yang X et al: Successful treatment of perniosis with hydroxychloroquine.
  • Ohmichi M et al: [Sarcoidosis associated with lupus pernio and acute pulmonary cavitation].

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707323987.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


26. Cooper IF, Siadaty MS: 'Functional Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; FunctionalConcept;AdverseEffectCold:707098683. ISSN: 2331-5717. 2014/4/5
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  • [Title] 'Functional Concepts' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Functional Concept' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Functional Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 264 publications.
  • Here are the top 10.
  • Anjaneyan G et al: Lupus pernio without systemic involvement.
  • Rice G et al: Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome.
  • Guadagni M et al: Acute perniosis in elderly people: a predictive sign of systemic disease?.
  • Richez C et al: Infliximab induced chilblain lupus in a patient with rheumatoid arthritis.
  • Prakash S et al: Idiopathic chilblains.
  • Cribier B et al: A histologic and immunohistochemical study of chilblains.
  • Ozmen M et al: The capillaroscopic findings in idiopathic pernio: is it a microvascular disease?.
  • Takci Z et al: Epidemiological patterns of perniosis, and its association with systemic disorder.
  • Price RD et al: Perniosis (chilblains) of the thigh: report of five cases, including four following river crossings.
  • Baughman RP et al: Chronic facial sarcoidosis including lupus pernio: clinical description and proposed scoring systems.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707098683.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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27. Cooper IF, Siadaty MS: 'Steroids' associated with 'Adverse Effect Cold Chilblains': Top Publications. BioMedLib Review; Steroid;AdverseEffectCold:705522304. ISSN: 2331-5717. 2014/11/24
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  • [Title] 'Steroids' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Steroid' for 'adverse effect cold chilblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Steroid'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 22 publications, and group two 287 publications.
  • Here are the top 10.
  • Khachemoune A: Papules and plaques on the nose. Lupus pernio.
  • Weismann K et al: Pernio of the hips in young girls wearing tight-fitting jeans with a low waistband.
  • Sugiura K et al: Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.
  • Noaimi AA et al: Treatment of perniosis with oral pentoxyfylline in comparison with oral prednisolone plus topical clobetasol ointment in Iraqi patients.
  • Price RD et al: Perniosis (chilblains) of the thigh: report of five cases, including four following river crossings.
  • Stewart CL et al: Equestrian perniosis: a report of 2 cases and a review of the literature.
  • Li Z: Thermotherapy: a novel possible treatment strategy of chronic rhinosinusitis based on the chilblain-like alteration in the early pathophysiology.
  • Souwer IH et al: Chilblains from the patient's perspective.
  • Viguier M et al: Clinical and histopathologic features and immunologic variables in patients with severe chilblains. A study of the relationship to lupus erythematosus.
  • Payne-James JJ et al: Pseudosclerodermatous triad of perniosis, pulp atrophy and 'parrot-beaked' clawing of the nails--a newly recognized syndrome of chronic crack cocaine use.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705522304.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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28. Banzon TM, Norton SA: Frostbite and chilblains in Upton Sinclair's The Jungle. JAMA Dermatol; 2015 Apr;151(4):421
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frostbite and chilblains in Upton Sinclair's The Jungle.
  • [MeSH-major] Chilblains / history. Frostbite / history. Literature, Modern

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  • (PMID = 25853456.001).
  • [ISSN] 2168-6084
  • [Journal-full-title] JAMA dermatology
  • [ISO-abbreviation] JAMA Dermatol
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
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29. Raza N, Habib A, Razvi SK, Dar NR: Constitutional and behavioral risk factors for chilblains: a case-control study from Pakistan. Wilderness Environ Med; 2010 Mar;21(1):17-21.e1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Constitutional and behavioral risk factors for chilblains: a case-control study from Pakistan.
  • OBJECTIVES: To study constitutional and behavioral risk factors for chilblains in patients at Abbottabad and Sialkot, Pakistan.
  • METHODS: One hundred patients and matched controls completed a single-page, close-ended questionnaire which included demographic data and questions related to possible constitutional and behavioral risk factors for chilblains.
  • Twenty-six patients and 3 controls had a positive family history for chilblains (odds ratio = 9.33); 42 patients and 14 controls reported a history of constipation (odds ratio = 2.69); 32 patients and 8 controls had a history of either numbness or tingling of fingers or toes (odds ratio = 2.93); 55 patients and 45 controls led sedentary lifestyles (odds ratio = 1.27); 85 patients and 58 controls consumed a low number of cups of tea daily (odds ratio = 3.20); 65 patients and 29 controls frequently washed their hands and/or feet (odds ratio = 4.93); and 56 patients and 33 controls had occasional sun exposure during winter months (odds ratio = 2.08).
  • CONCLUSION: Significant risk factors for the development of chilblains for people at Abbottabad and Sialkot included a history of chilblains in first-degree relatives, numbness and tingling sensations of fingers or toes, frequent hand or feet washing, and lower tea consumption during winter months.
  • [MeSH-major] Altitude. Chilblains / epidemiology. Cold Temperature
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Beverages. Case-Control Studies. Child. Child, Preschool. Female. Genetic Predisposition to Disease. Hand Disinfection. Humans. Male. Middle Aged. Multivariate Analysis. Odds Ratio. Pakistan. Risk Factors. Tea. Young Adult

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  • [Copyright] Copyright (c) 2010 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20591349.001).
  • [ISSN] 1545-1534
  • [Journal-full-title] Wilderness & environmental medicine
  • [ISO-abbreviation] Wilderness Environ Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tea
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30. Padeh S, Gerstein M, Greenberger S, Berkun Y: Chronic chilblains: the clinical presentation and disease course in a large paediatric series. Clin Exp Rheumatol; 2013 May-Jun;31(3):463-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic chilblains: the clinical presentation and disease course in a large paediatric series.
  • OBJECTIVES: Children often present during winter with painful, red-purple swollen fingers and/or toes, usually misdiagnosed as Raynaud's phenomenon.
  • Pernio, or chronic chilblains, is a localised inflammatory lesion of the skin resulting from an abnormal response to cold.
  • The aim of this study was to better characterise the clinical presentation of chronic chilblains in children.
  • METHODS: This is a single-centre retrospective study of patients referred to our paediatric rheumatology clinic with cold, purple, and painful hands.
  • Data of the clinical presentation, physical findings, laboratory investigations and the course of the disease were extracted from the patients' charts and analysed.
  • Patients age at presentation was 13.5±2.1, and disease duration was 2.0±1.0 winters.
  • Fingers swelling was the most common finding (81.8%), followed by proximal interphalangeal joint (PIPs) swelling (63.6%), skin ulceration (54.5%), and dry, irritated skin (45.5%).
  • CONCLUSIONS: We report a large series of children with a unique symptomatology consisting in chronic chilblains.
  • [MeSH-major] Antibodies, Antinuclear / immunology. Chilblains / diagnosis. Raynaud Disease / diagnosis
  • [MeSH-minor] Adolescent. Arthritis / diagnosis. Arthritis / etiology. Child. Chronic Disease. Cohort Studies. Diagnosis, Differential. Disease Progression. Edema / diagnosis. Edema / etiology. Female. Finger Joint / pathology. Humans. Male. Physical Examination. Retrospective Studies. Skin Ulcer / diagnosis. Skin Ulcer / etiology

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  • (PMID = 23414913.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear
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31. Pramanik T, Jha AK, Ghimire A: A retrospective study of cases presenting with chilblains (Perniosis) in Out Patient Department Of Dermatology, Nepal Medical College and Teaching Hospital (NMCTH). Nepal Med Coll J; 2011 Sep;13(3):190-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A retrospective study of cases presenting with chilblains (Perniosis) in Out Patient Department Of Dermatology, Nepal Medical College and Teaching Hospital (NMCTH).
  • Chilblains (Perniosis/Pernio) is characterized by painful red-to-purple papular lesions involving the fingers or toes due to non-freezing damp cold that resolves with symptomatic treatment.
  • As in winters, cold is moderate to severe in Kathmandu, this retrospective study was undertaken to find out the incidence of chilblains cases, seeking health care in the Out Patient Department of Dermatology, Nepal Medical College and Teaching Hospital.
  • Cases of chilblains were noted in the months of October to December 2009, January to March 2010, October to December 2010 and January to March 2011.
  • Most of (79.6%) the chilblain victims sought health care during the months of December to February -- coldest time of the years.
  • The patients were advised to protect their acral parts from cold exposure as far as practicable by wearing shocks and gloves.
  • They were advised not to warm their extremities all on a sudden, after exposure to cold, as this causes vasospasm and makes the condition worse.
  • [MeSH-major] Chilblains / epidemiology. Dermatology. Hospitals, Teaching. Outpatient Clinics, Hospital

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  • (PMID = 22808813.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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32. Gardinal-Galera I, Pajot C, Paul C, Mazereeuw-Hautier J: Childhood chilblains is an uncommon and invalidant disease. Arch Dis Child; 2010 Jul;95(7):567-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Childhood chilblains is an uncommon and invalidant disease.
  • [MeSH-major] Chilblains / etiology. Cryoglobulinemia / complications
  • [MeSH-minor] Adolescent. Child. Chronic Disease. Female. Follow-Up Studies. Humans. Male. Retrospective Studies

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  • (PMID = 20522476.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
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33. Ayli EE, Ingraffea A, Weinman M, Gloster HM Jr: Chilblains in a Mohs histotechnician. Dermatol Surg; 2012 Sep;38(9):1555-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains in a Mohs histotechnician.
  • [MeSH-major] Chilblains / etiology. Cold Temperature / adverse effects. Cryoultramicrotomy. Occupational Exposure / adverse effects

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  • (PMID = 22691068.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; F446C597KA / Triamcinolone Acetonide
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34. Robb-Nicholson C: By the way, doctor. I've been diagnosed as having chilblains in the fingers on both hands. What causes chilblains? Is there a cure? Harv Womens Health Watch; 2010 Dec;18(4):8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] By the way, doctor. I've been diagnosed as having chilblains in the fingers on both hands. What causes chilblains? Is there a cure?
  • [MeSH-major] Chilblains / drug therapy. Chilblains / prevention & control. Cholecalciferol / therapeutic use. Fingers. Health Knowledge, Attitudes, Practice. Self Medication / methods
  • [MeSH-minor] Cold Temperature / adverse effects. Humans. Risk Factors. Vitamins / therapeutic use

  • HSDB. CHOLECALCIFEROL .
  • HSDB. CHOLECALCIFEROL .
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  • (PMID = 21275088.001).
  • [ISSN] 1070-910X
  • [Journal-full-title] Harvard women's health watch
  • [ISO-abbreviation] Harv Womens Health Watch
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vitamins; 1C6V77QF41 / Cholecalciferol
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35. Cappel JA, Wetter DA: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011. Mayo Clin Proc; 2014 Feb;89(2):207-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • OBJECTIVE: To further characterize the clinical features, etiologic associations, laboratory findings, and treatment of pernio.
  • PATIENTS AND METHODS: This is a retrospective review of patients with pernio seen at our institution between January 1, 2000, and December 31, 2011.
  • RESULTS: Of 104 patients with pernio (mean age at diagnosis, 38.3 years), 82 (79%) were women.
  • Pernio affected the toes in 85 patients (82%) and the fingers in 31 (30%).
  • Thirty-eight patients (37%) had at least 1 abnormal laboratory test result, and test results were positive for cold agglutinins in 11 (55%) of 20 tested patients.
  • Four patients (4%) had connective tissue disease (nonlupus) associated with pernio; 3 patients (3%) had an associated hematologic malignant disease.
  • CONCLUSION: To our knowledge, this study represents one of the largest single-center case series of pernio to date.
  • Most of the patients did not have an underlying systemic association with pernio, although a few patients had pernio in association with connective tissue disease or hematologic malignant disease.
  • [MeSH-major] Chilblains / diagnosis. Chilblains / etiology. Chilblains / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy. Child. Diagnosis, Differential. Female. Humans. Lupus Erythematosus, Systemic / complications. Male. Middle Aged. Risk Factors. Treatment Outcome

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  • [Copyright] Copyright © 2014 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
  • (PMID = 24485134.001).
  • [ISSN] 1942-5546
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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36. Lutz V, Cribier B, Lipsker D: Chilblains and antiphospholipid antibodies: report of four cases and review of the literature. Br J Dermatol; 2010 Sep;163(3):645-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chilblains and antiphospholipid antibodies: report of four cases and review of the literature.
  • [MeSH-major] Antibodies, Antiphospholipid / analysis. Chilblains / immunology
  • [MeSH-minor] Adolescent. Adult. Antiphospholipid Syndrome / diagnosis. Antiphospholipid Syndrome / immunology. Biopsy. Female. Humans. Lupus Erythematosus, Systemic / diagnosis. Lupus Erythematosus, Systemic / immunology. Middle Aged

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  • (PMID = 20426783.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Antiphospholipid
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37. Larkins N, Murray KJ: Major cluster of chilblain cases in a cold dry Western Australian winter. J Paediatr Child Health; 2013 Feb;49(2):144-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Major cluster of chilblain cases in a cold dry Western Australian winter.
  • AIM: Primary chilblains are an idiopathic cold-induced vasculopathy affecting the soft tissues of the hands and feet.
  • Secondary chilblains occur in different forms of vasculitis and chronic autoimmune connective tissue disorders.
  • Idiopathic chilblains are rarely reported in children and may generate significant anxiety to doctors and patients.
  • We describe a cluster of idiopathic chilblains encountered over the winter of 2010 in Perth, Western Australia.
  • RESULTS: Thirty-two patients with isolated idiopathic chilblains were included, including 20 females and 12 males with a median age at onset of 13.5 years.
  • Most patients improved spontaneously with warmer weather or responded to cold protection advice.
  • CONCLUSION: Our cluster of chilblains was associated with an unusually cold winter in Perth 2010.
  • It is the largest series reported in the literature, suggesting that chilblains may be more common than previously thought.
  • Chilblains are almost always benign in nature and patients are systemically well and usually need no further investigation and only symptomatic treatment.
  • [MeSH-major] Chilblains / epidemiology. Cold Temperature / adverse effects. Seasons

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  • [Copyright] © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
  • (PMID = 23356736.001).
  • [ISSN] 1440-1754
  • [Journal-full-title] Journal of paediatrics and child health
  • [ISO-abbreviation] J Paediatr Child Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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38. Guly HR: Frostbite and other cold injuries in the heroic age of Antarctic exploration. Wilderness Environ Med; 2012 Dec;23(4):365-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frostbite and other cold injuries in the heroic age of Antarctic exploration.
  • Frostbite and other cold injuries on the early polar expeditions were common.
  • Nonfreezing cold injury probably also occurred but was not differentiated from frostbite, and chilblains were also described.
  • [MeSH-major] Cold Temperature / adverse effects. Environmental Exposure / adverse effects. Expeditions / history. Frostbite / history

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  • [Copyright] Copyright © 2012 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
  • (PMID = 22835802.001).
  • [ISSN] 1545-1534
  • [Journal-full-title] Wilderness & environmental medicine
  • [ISO-abbreviation] Wilderness Environ Med
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / /
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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39. Takci Z, Vahaboglu G, Eksioglu H: Epidemiological patterns of perniosis, and its association with systemic disorder. Clin Exp Dermatol; 2012 Dec;37(8):844-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiological patterns of perniosis, and its association with systemic disorder.
  • BACKGROUND: There are few studies exploring the epidemiological properties of perniosis (chilblains) and its association with systemic disorders.
  • AIM: To collect epidemiological data for perniosis, to investigate any association with systemic disorders, and to identify markers for the differential diagnosis of idiopathic and secondary perniosis.
  • METHODS: This was a prospective study of 51 patients with perniosis [female : male ratio 2.64 : 1, mean ± SD age 24.6 ± 14.7 years, with 25 patients (49%) aged 0-18 years].
  • RESULTS: Significant proportions of the patients had both chronic and idiopathic perniosis (P < 0.001 for both).
  • The mean age of the group with secondary perniosis was significantly higher than that of the idiopathic group (P < 0.01).
  • There was no significant gender difference in the secondary perniosis group (P = 0.71).
  • Persistence beyond the cold seasons, and presence of photosensitivity, hypergammaglobulinaemia and rheumatoid factor were significant findings in the secondary group (P = 0.02, P = 0.02, P < 0.01, P < 0.05, respectively).
  • CONCLUSIONS: Perniosis is not rare in children, but patients with secondary perniosis are more likely to be older.
  • In terms of underlying systemic disorder, advanced age and male gender may be important demographic features.
  • Measurement of cryoglobulin levels in the initial laboratory investigations of patients with perniosis is not necessary.
  • Persistence beyond the cold seasons, and presence of photosensitivity, hypergammaglobulinaemia and rheumatoid factor may be useful in differentiating between idiopathic and secondary perniosis.
  • [MeSH-major] Chilblains / epidemiology
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Age Distribution. Aged. Biological Markers / analysis. Child. Child, Preschool. Chronic Disease. Diagnosis, Differential. Female. Humans. Infant. Male. Middle Aged. Prevalence. Prospective Studies. Risk Factors. Seasons. Sex Factors. Young Adult

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  • [Copyright] © The Author(s). CED © 2012 British Association of Dermatologists.
  • (PMID = 23082992.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biological Markers
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40. 'Parrot Like Nose': Top Publications. BioMedLib Review CN; ;ParrotLikeNose:710405129. ISSN: 2331-5717. 2015/7/20; updates online.
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  • [Title] 'Parrot Like Nose': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'parrot like nose'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 5 publications.
  • Here are the top 3.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Guízar-Vázquez J et al: Peculiar face, pectus carinatum and joint laxity in brother and sister.
  • Eichhorn-Sens J et al: [Overresection of the lower lateral cartilage. A frequent cause for revision rhinoplasty].

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710405129.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review CN
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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41. Massey PR, Wanat KA, Stewart CL, Kim EJ, Castelo-Soccio L, Elenitsas R, Rubin AI: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition. Am J Dermatopathol; 2014 Sep;36(9):730-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.
  • In classical clinical perniosis (chilblains), the presence of atypical lymphocytes with immunohistochemical staining positive for CD30 is unusual and rarely reported.
  • Here we report 2 cases of clinical perniosis, one in a 16-year-old girl and another in a 67-year-old woman.
  • Dermatopathologists must be aware of this potential histologic pattern in perniosis to prevent misdiagnosis and overtreatment of this condition.
  • [MeSH-major] Antigens, CD30 / immunology. Chilblains / immunology. Chilblains / pathology. Lymphocytes / immunology. Lymphocytes / pathology

  • Genetic Alliance. consumer health - Perniosis.
  • ResearchGate. author profiles.
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  • (PMID = 25072680.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30
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42. 'Capillary Refill Test Of Toes': Top Publications. BioMedLib Review CN; ;CapillaryRefillTest:709172795. ISSN: 2331-5717. 2015/8/9; updates online.
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  • [Title] 'Capillary Refill Test Of Toes': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'capillary refill test of toes'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 2 publications.
  • Here is the first one.
  • Johnson DE: When pain is out of proportion.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709172795.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review CN
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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43. 'Chilblain Disorder': Top Publications. BioMedLib Review OC; ;ChilblainDisorder:709920505. ISSN: 2331-5717. 2015/1/10; updates online.
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  • [Title] 'Chilblain Disorder': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblain disorder'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Shah A et al: Lupus pernio--a patient case study.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920505.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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44. Vogt J, Agrawal S, Ibrahim Z, Southwood TR, Philip S, Macpherson L, Bhole MV, Crow YJ, Oley C: Striking intrafamilial phenotypic variability in Aicardi-Goutières syndrome associated with the recurrent Asian founder mutation in RNASEH2C. Am J Med Genet A; 2013 Feb;161A(2):338-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The disorder demonstrates significant genetic heterogeneity with causative mutations in five genes identified to date.
  • A later presentation with a more variable effect on development, morbidity and mortality has been particularly observed in association with mutations in SAMHD1 and RNASEH2B.
  • In this family, one female child had a severe AGS phenotype with an onset in infancy and profound developmental delay, whilst an older sister was of completely normal intellect with a normal head circumference and was only diagnosed because of the presence of chilblains and a mild hemiplegia.
  • An appreciation of intrafamilial phenotypic expression is important in the counseling of families considering prenatal diagnosis, and may also be relevant to the assessment of efficacy in future clinical trials.
  • [MeSH-minor] Abnormalities, Multiple / genetics. Brain Diseases / genetics. Chilblains / genetics. Child, Preschool. Consanguinity. Female. Founder Effect. Hemiplegia / genetics. Humans. Infant. Phenotype

  • Genetic Alliance. consumer health - Aicardi Syndrome.
  • Genetic Alliance. consumer health - Aicardi-Goutieres Syndrome.
  • MedlinePlus Health Information. consumer health - Brain Malformations.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • ResearchGate. author profiles.
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  • [Copyright] Copyright © 2013 Wiley Periodicals, Inc.
  • (PMID = 23322642.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.26.- / ribonuclease HII; EC 3.1.26.4 / Ribonuclease H; Aicardi-Goutieres syndrome
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45. 'Idiopathic Pernioses': Top Publications. BioMedLib Review OC; ;IdiopathicPernioses:707921437. ISSN: 2331-5717. 2015/4/10; updates online.
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  • [Title] 'Idiopathic Pernioses': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'idiopathic pernioses'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

  • [Email] Email this result item
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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707921437.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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46. 'Erythema Pernio': Top Publications. BioMedLib Review OC; ;ErythemaPernio:709920528. ISSN: 2331-5717. 2015/1/10; updates online.
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  • [Title] 'Erythema Pernio': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'erythema pernio'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920528.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


47. 'Idiopathic Perniosis': Top Publications. BioMedLib Review OC; ;IdiopathicPerniosis:709920472. ISSN: 2331-5717. 2015/11/10; updates online.
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Idiopathic Perniosis': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'idiopathic perniosis'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • António AM et al: Idiopathic perniosis of the buttocks and thighs - clinical report.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.
  • Shah A et al: Lupus pernio--a patient case study.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709920472.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


48. 'Pernios': Top Publications. BioMedLib Review OC; ;Pernios:707921438. ISSN: 2331-5717. 2015/5/10; updates online.
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  • [Title] 'Pernios': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'pernios'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707921438.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


49. 'Chillblains': Top Publications. BioMedLib Review OC; ;Chillblains:707921436. ISSN: 2331-5717. 2015/11/10; updates online.
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Chillblains': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chillblains'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.
  • Abe J et al: A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707921436.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


50. 'Chilblained': Top Publications. BioMedLib Review OC; ;Chilblained:707921434. ISSN: 2331-5717. 2015/5/10; updates online.
PDF icon [Fulltext service] Download fulltext PDF of this article.

  • [Title] 'Chilblained': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'chilblained'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 30 publications, and group two 128 publications.
  • Here are the top 10.
  • Akkurt ZM et al: Chilblains in Turkey: a case-control study.
  • Gordon R et al: Chilblains in Southern California: two case reports and a review of the literature.
  • Bansal S et al: Chilblain lupus erythematosus in an adolescent girl.
  • Ozuguz P et al: Does pernio cause nail dystrophy?.
  • Cooper IF et al: 'Therapeutic or Preventive Procedures' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Cappel JA et al: Clinical characteristics, etiologic associations, laboratory findings, treatment, and proposal of diagnostic criteria of pernio (chilblains) in a series of 104 patients at Mayo Clinic, 2000 to 2011.
  • Cooper IF et al: 'Hormones' associated with 'Adverse Effect Cold Chilblains': Top Publications.
  • Külcü Çakmak S et al: Demographical, laboratory and associated findings in patients with perniosis.
  • Shah A et al: Lupus pernio--a patient case study.
  • Massey PR et al: CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707921434.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
  •  go-up   go-down


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