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1. Biomedical articles (top 50; 2010 to 2015)
1. Moloney TP, Trinh T, Farrah JJ: A case of conjunctival mucoepidermoid carcinoma in Australia. Clin Ophthalmol; 2014;8:11-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of conjunctival mucoepidermoid carcinoma in Australia.
  • Conjunctival mucoepidermoid carcinoma is a very rare but highly aggressive conjunctival neoplasm with 42 previously reported cases.
  • We report the case of a 56-year-old male with a left ocular surface squamous neoplasm, which was subsequently treated with excision and autoconjunctival graft.
  • Histopathology of the operative specimen reported a low-grade conjunctival mucoepidermoid carcinoma, and the patient was then treated with an adjunctive course of mitomycin C.
  • Due to its rare incidence, difficult clinical diagnosis, and accompanying poor prognosis, conjunctival mucoepidermoid carcinoma should always be considered in the differential diagnosis of conjunctival neoplasms, and full histopathologic examination, including mucin-staining techniques, of all suspicious conjunctival biopsies should occur.

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  • (PMID = 24363552.001).
  • [ISSN] 1177-5467
  • [Journal-full-title] Clinical ophthalmology (Auckland, N.Z.)
  • [ISO-abbreviation] Clin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3862775
  • [Keywords] NOTNLM ; conjunctiva / mitomycin C / neoplasm / pterygium
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2. Maschi C, Caujolle JP, Liolios I, Costet C: [Benign conjunctival tumors]. J Fr Ophtalmol; 2013 Nov;36(9):796-802
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign conjunctival tumors].
  • [Transliterated title] Tumeurs conjonctivales bénignes.
  • Benign conjunctival tumors include congenital, melanocytic, epithelial and stromal lesions.
  • Clinical observation often fails to make the diagnosis, and complete excisional biopsy must be performed as soon as growth is suspected.
  • Onco-ophthalmologists must have a perfect knowledge of benign conjunctival tumors, since during adulthood, nevi can be confused with melanomas, and epithelial or stromal lesions with carcinomas.
  • [MeSH-major] Conjunctival Neoplasms
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / pathology. Adolescent. Adult. Humans. Keratoacanthoma / diagnosis. Keratoacanthoma / pathology. Melanoma / diagnosis. Melanoma / pathology. Neoplasms, Nerve Tissue / diagnosis. Neoplasms, Nerve Tissue / pathology. Neoplasms, Vascular Tissue / diagnosis. Neoplasms, Vascular Tissue / pathology. Nevus, Pigmented / diagnosis. Nevus, Pigmented / pathology

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  • [Copyright] Copyright © 2013 Elsevier Masson SAS. All rights reserved.
  • (PMID = 24099696.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Keywords] NOTNLM ; Congenital tumors / Conjonctive / Conjunctiva / Epithelial tumors / Melanocytic tumors / Stromal tumors / Tumeurs congénitales / Tumeurs mélaniques / Tumeurs stromales / Tumeurs épithéliales
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3. Levy-Gabriel C: [Suspicious conjunctival lesions]. J Fr Ophtalmol; 2010 Feb;33(2):125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Suspicious conjunctival lesions].
  • [Transliterated title] Taches suspectes de la conjonctive.
  • The main conjunctival tumors are represented by (i) conjunctival melanoma, ocular surface squamous neoplasia, and conjunctival lymphoma, which are malignant tumors, and (ii) conjunctival nevus, papilloma, and choristoma, which are benign.
  • In usual practice, ophthalmologists need to know how to differentiate conjunctival melanomas and carcinomas from the other conjunctival tumors by clinical examination.
  • Indeed, the therapeutic approach to these two malignant diseases presents a number of particularities such as the need for surgery under general anesthesia, if possible, to minimize the risk of local dissemination and further local recurrence, and detailed information on the tumor location and measurements before surgery (Figures, diagram, sizes) to precisely define the irradiation field during complementary radiotherapy.
  • The clinical signs and main therapeutic principles of conjunctival tumors are reviewed in this article.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Conjunctival Neoplasms / therapy. Ophthalmology / methods
  • [MeSH-minor] Choristoma / diagnosis. Combined Modality Therapy. Diagnosis, Differential. Humans. Lymphoma / diagnosis. Melanoma / diagnosis. Neoplasm Staging. Neoplasms, Squamous Cell / diagnosis. Nevus / diagnosis. Papilloma / diagnosis. Pigmentation. Precancerous Conditions / diagnosis

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20096479.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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4. Alves LF, Fernandes BF, Burnier JV, Zoroquiain P, Eskenazi DT, Burnier Jr MN: Incidence of epithelial lesions of the conjunctiva in a review of 12,102 specimens in Canada (Quebec). Arq Bras Oftalmol; 2011 Jan-Feb;74(1):21-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence of epithelial lesions of the conjunctiva in a review of 12,102 specimens in Canada (Quebec).
  • PURPOSE: The purpose of this study was to assess the relative frequency of epithelial lesions of the conjunctiva in Canada.
  • The relative frequency of epithelial lesions of the conjunctiva from a single center in Canada, representing the province of Quebec was reviewed.
  • RESULTS: Of the 12,102 specimens reviewed, 273 were conjunctival lesions (2.25%), including 86 epithelial tumors (0.71%) of the conjunctiva that comprised the studied sample.
  • Within the ocular surface squamous neoplasia (OSSN) spectrum, there were 10 (11.6%) actinic keratosis (63.8 ± 17.6 years), 27 (31.3%) cases of conjunctival intraepithelial neoplasia (CIN) with variable degrees of atypia (mild to moderate) (63.9 ± 15.3 years), 15 (17.4%) carcinomas in situ (66.7 ± 18.0 years), and 17 (19.7%) squamous cell carcinomas (SCC) (56.2 ± 19.4 years).
  • Two other rare cases of malignant tumors included one basal cell carcinoma and one mucoepidermoid carcinoma.
  • When we compare our sample to others coming from countries with high levels of sunlight exposure, we found a lower incidence of ocular surface squamous neoplasia, including squamous cell carcinomas in Canada.
  • [MeSH-major] Conjunctival Neoplasms / epidemiology

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  • (PMID = 21670902.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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5. Matsuo T, Ichimura K, Kubonishi S: Mantle cell lymphoma diagnosed by conjunctival salmon-pink lesion biopsy. J Clin Exp Hematop; 2014;54(2):143-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mantle cell lymphoma diagnosed by conjunctival salmon-pink lesion biopsy.
  • Conjunctival lesions are rarely seen in mantle cell lymphoma.
  • Here, we report a patient who developed bilateral conjunctival lesions in the course of chronic lymphocytic leukemia as an initial diagnosis, resulting in the final diagnosis of mantle cell lymphoma by conjunctival biopsy.
  • A 66-year-old man developed conjunctival salmon-pink lesions on both sides in the 1.5-year course of chronic lymphocytic leukemia.
  • Bilateral conjunctival biopsy showed subepithelial infiltration with lymphoid cells, positive for CD20, CD5, and cyclin D1, but negative for CD3, CD10, and CD23.
  • Immunohistochemical restaining of the previous bone marrow biopsy specimen demonstrated lymphoid cells positive for cyclin D1, confirming the diagnosis of mantle cell lymphoma with leukemic presentation.
  • In conclusion, mantle cell lymphoma should be included in the differential diagnosis of conjunctival salmon-pink lesions.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Lymphoma, Mantle-Cell / diagnosis

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  • (PMID = 25318947.001).
  • [ISSN] 1880-9952
  • [Journal-full-title] Journal of clinical and experimental hematopathology : JCEH
  • [ISO-abbreviation] J Clin Exp Hematop
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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6. Kenawy N, Lake SL, Coupland SE, Damato BE: Conjunctival melanoma and melanocytic intra-epithelial neoplasia. Eye (Lond); 2013 Feb;27(2):142-52
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  • [Title] Conjunctival melanoma and melanocytic intra-epithelial neoplasia.
  • The rarity of conjunctival melanoma has impeded progress in the management of patients with this cancer; however, much progress has occurred in recent years.
  • Primary acquired melanosis is now differentiated histologically into hypermelanosis and conjunctival melanocytic intra-epithelial neoplasia, for which an objective reproducible scoring system has been developed.
  • Mapping and clinical staging of conjunctival disease has improved.
  • Adjunctive radiotherapy and topical chemotherapy have made tumour control more successful, with reduced morbidity.
  • Genetic analyses have identified BRAF and other mutations, which may predict responsiveness to new chemotherapeutic agents, for example Vemurafenib, should metastatic disease develop.
  • Multicentre studies are under way to enhance survival prediction by integrating clinical stage of disease with histological grade of malignancy and genetic abnormalities.
  • [MeSH-major] Conjunctival Neoplasms / classification. Melanoma / classification
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Staging. Proto-Oncogene Proteins B-raf / genetics

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  • (PMID = 23222568.001).
  • [ISSN] 1476-5454
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
  • [Other-IDs] NLM/ PMC3574254
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7. 'Conjunctival Neoplasms Disease Finding': Top Publications. BioMedLib Review OC; ;ConjunctivalNeoplasmsDisease:710007583. ISSN: 2331-5717. 2015/1/12; updates online.
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  • [Title] 'Conjunctival Neoplasms Disease Finding': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'conjunctival neoplasms disease finding'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 126 publications, and group two 770 publications.
  • Here are the top 8.
  • Tuncer S et al: Regression of conjunctival tumor during dietary treatment of celiac disease.
  • Cooper IF et al: 'Ideas or Concepts' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • Cooper IF et al: 'Intellectual Products' associated with 'Malignant Conjunctiva Neoplasm': Top Publications.
  • Ranjbar M et al: [Prominent conjunctival tumor].
  • Chen HM et al: Localized peripheral primitive neuroectodermal tumor of the conjunctiva: a rare presentation.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Cooper IF et al: 'Functional Concepts' associated with 'Benign Conjunctiva Neoplasm': Top Publications.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710007583.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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8. Cooper IF, Siadaty MS: 'Neoplastic Processes' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; NeoplasticProcess;ConjunctivalNeoplasm:706156063. ISSN: 2331-5717. 2014/12/23
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  • [Title] 'Neoplastic Processes' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Neoplastic Process' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Neoplastic Process'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 27 publications, and group two 1502 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Steroids' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Ranjbar M et al: [Prominent conjunctival tumor].
  • Chen Z et al: Amniotic membrane transplantation for conjunctival tumor.
  • Pe'er J et al: Solitary fibrous tumor of the conjunctiva.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Tuncer S et al: Regression of conjunctival tumor during dietary treatment of celiac disease.
  • Kim JW et al: Topical treatment options for conjunctival neoplasms.
  • Matsuo T et al: Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
  • Yeatts RP et al: 5-Fluorouracil for the treatment of intraepithelial neoplasia of the conjunctiva and cornea.
  • Rodriguez-Sains RS: Pigmented conjunctival neoplasms.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706156063.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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9. Marr BP, Abramson DH, Cohen GN, Williamson MJ, McCormick B, Barker CA: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity. JAMA Ophthalmol; 2015 Mar;133(3):283-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • IMPORTANCE: Adjunct treatments for conjunctival malignancies are needed when standard therapy provides limited benefits or fails.
  • OBJECTIVE: To describe the results of patients with diffuse conjunctival neoplasms treated with radioactive phosphorus 32 (32P)-impregnated flexible film.
  • The study was conducted on 7 eyes of 6 patients treated for diffuse conjunctival squamous cell carcinoma, sebaceous carcinoma, or lymphoma that had recurrent or residual disease after primary treatment.
  • INTERVENTIONS: Patients underwent mapping biopsies and detailed conjunctival drawings to delineate the pathologic extent of the disease.
  • All patients had a recurrent or persistent neoplasm.
  • Visual acuity was stable or improved in 5 of the 7 eyes (ie, better than 20/70 in the 5 patients who retained their treated eye).
  • CONCLUSIONS AND RELEVANCE: Our results show the use of an intraoperative high-dose rate of 32P brachytherapy in selected cases of recalcitrant diffuse conjunctival neoplasms.
  • [MeSH-major] Adenocarcinoma, Sebaceous / radiotherapy. Brachytherapy / methods. Carcinoma, Squamous Cell / radiotherapy. Conjunctival Neoplasms / radiotherapy. Lymphoma, T-Cell / radiotherapy. Phosphorus Radioisotopes / therapeutic use
  • [MeSH-minor] Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Intraoperative Care. Male. Middle Aged. Radiotherapy Dosage. Radiotherapy, Adjuvant. Retrospective Studies. Visual Acuity / physiology

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  • (PMID = 25502420.001).
  • [ISSN] 2168-6173
  • [Journal-full-title] JAMA ophthalmology
  • [ISO-abbreviation] JAMA Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Phosphorus Radioisotopes
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10. Özcan AA, Çiloğlu E, Esen E, Şimdivar GH: Use of topical bevacizumab for conjunctival intraepithelial neoplasia. Cornea; 2014 Nov;33(11):1205-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of topical bevacizumab for conjunctival intraepithelial neoplasia.
  • PURPOSE: To report our experience in the treatment of intraepithelial neoplasia of the conjunctiva using topical bevacizumab.
  • METHODS: Ten eyes of 10 patients with conjunctival neoplasia received 25 mg/mL bevacizumab topically.
  • The size and vascularity of the tumors reduced weekly.
  • The histopathologic diagnosis of the lesions was carcinoma in situ.
  • CONCLUSIONS: Topical bevacizumab is an effective treatment to reduce the tumor size before surgery and may be a good alternative for adjuvant therapy of conjunctival neoplasms.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Antibodies, Monoclonal, Humanized / therapeutic use. Carcinoma in Situ / drug therapy. Conjunctival Neoplasms / drug therapy. Neovascularization, Pathologic / drug therapy

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  • (PMID = 25014150.001).
  • [ISSN] 1536-4798
  • [Journal-full-title] Cornea
  • [ISO-abbreviation] Cornea
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal, Humanized; 0 / Ophthalmic Solutions; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 2S9ZZM9Q9V / bevacizumab
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11. Wiggans KT, Skorupski KA, Reilly CM, Frazier SA, Dubielzig RR, Maggs DJ: Presumed solitary intraocular or conjunctival lymphoma in dogs and cats: 9 cases (1985-2013). J Am Vet Med Assoc; 2014 Feb 15;244(4):460-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Presumed solitary intraocular or conjunctival lymphoma in dogs and cats: 9 cases (1985-2013).
  • RESULTS: Animals with intraocular (4 dogs and 1 cat) or conjunctival (3 dogs and 1 cat) lymphoma represented 0.1% and 0.08% of patients with lymphoma evaluated at the hospital during the study period, respectively.
  • Animals with intraocular lymphoma represented 0.19% of all patients with uveitis; animals with conjunctival lymphoma represented 0.16% of all patients with conjunctivitis.
  • Tumors included B-cell (2 intraocular and 1 conjunctival), non-B-cell, non-T-cell (1 intraocular), and T-cell (3 conjunctival) neoplasms; immunophenotype of 2 uveal lymphomas was not determined.
  • Treatments included enucleation (4 intraocular) and chemotherapy (3 intraocular and 2 conjunctival).
  • Lymph node metastasis was detected in 2 patients with conjunctival lymphoma.
  • Median PFST and OST for animals with conjunctival lymphoma were 221 and 549 days, respectively.
  • CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated PSOL was uncommon, but should be considered a differential diagnosis for animals with uveitis or conjunctivitis.
  • Prognosis seemed to be better for animals with conjunctival lymphoma than it was for those with intraocular lymphoma.
  • [MeSH-major] Cat Diseases / diagnosis. Dog Diseases / diagnosis. Eye Neoplasms / veterinary. Lymphoma / veterinary

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  • (PMID = 24479461.001).
  • [ISSN] 1943-569X
  • [Journal-full-title] Journal of the American Veterinary Medical Association
  • [ISO-abbreviation] J. Am. Vet. Med. Assoc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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12. Harooni H, Schoenfield LR, Singh AD: Current appraisal of conjunctival melanocytic tumors: classification and treatment. Future Oncol; 2011 Mar;7(3):435-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current appraisal of conjunctival melanocytic tumors: classification and treatment.
  • Conjunctival melanocytic tumors represent a spectrum of pigmented tumors that include benign, premalignant and malignant tumors.
  • Conjunctival nevi are the most common pigmented tumors and are typically found in the interpalpebral bulbar conjunctiva.
  • Conjunctival melanoma represents only 5% of all melanomas arising in the ocular region and is associated with a high mortality rate.
  • The management of primary acquired melanosis, nevi and conjunctival melanomas involves various modalities used either alone or concomitantly depending on the size and extent of the lesion.
  • [MeSH-major] Conjunctival Neoplasms / classification. Conjunctival Neoplasms / therapy
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Humans. Melanoma / diagnosis. Melanoma / drug therapy. Melanoma / pathology. Melanoma / radiotherapy. Melanosis / drug therapy. Melanosis / pathology. Nevus, Pigmented / pathology. Prognosis

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  • (PMID = 21417906.001).
  • [ISSN] 1744-8301
  • [Journal-full-title] Future oncology (London, England)
  • [ISO-abbreviation] Future Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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13. Tost F, Evert M: [Conjunctival tumours in elderly patients]. Klin Monbl Augenheilkd; 2010 Jan;227(1):33-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Conjunctival tumours in elderly patients].
  • [Transliterated title] Tumoren der Bindehaut im Alter.
  • The conjunctiva as a mucous membrane provides a protective barrier to the eye.
  • For this reason conjunctival ageing is affected by equivalent processes as skin ageing.
  • The resulting dysfunction in conjunctival homoeostasis and protective function represent common factors which contribute to increased incidences of tumours and malignant transformations in elderly patients.
  • At the time of tumour manifestation the patient's age is an important parameter for differential diagnosis and regimen strategy.
  • [MeSH-major] Conjunctival Neoplasms / surgery. Ophthalmologic Surgical Procedures / methods
  • [MeSH-minor] Age Factors. Aged. Aged, 80 and over. Antibiotics, Antineoplastic / administration & dosage. Chemotherapy, Adjuvant. Combined Modality Therapy. Diagnosis, Differential. Humans. Middle Aged. Mitomycin / administration & dosage. Ophthalmic Solutions. Postoperative Complications / etiology. Postoperative Complications / surgery. Reoperation. Risk Factors

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 20091448.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Ophthalmic Solutions; 50SG953SK6 / Mitomycin
  • [Number-of-references] 52
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14. Zemba M, Stamate AC, Avram CI, Sîrbu LN, Camburu RL, Ochinciuc U, Burcea M: [Alternative therapeutic excision of intraepithelial conjunctival carcinoma with corneal extension]. Oftalmologia; 2013;57(4):22-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Alternative therapeutic excision of intraepithelial conjunctival carcinoma with corneal extension].
  • [Transliterated title] Alternative terapeutice la excizia unui carcinom intraepitelial conjunctival cu extensie corneeană.
  • Surgical treatment for conjunctival neoplasms, with wide local excision, with or without supplemental cryotherapy to the surgical margins represents the treatment of choice for this pathology.
  • In some cases, these neoplasms can be diffuse or multifocal, with borders that are difficult to detect clinically, such that topical therapies offer a more efficient method for treating the entire ocular surface, delivering high drug concentrations at this level, with negligible systemic side effects.
  • Beginning from the clinical case of a patient diagnosed with conjunctival intraepithelial neoplasia, we try to present other therapeutical alternatives, although in this case the therapeutical approach was the classic one.
  • [MeSH-major] Carcinoma in Situ / surgery. Conjunctival Neoplasms / surgery. Cornea / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Neoplasm Invasiveness. Neoplasm Staging. Ophthalmic Solutions / administration & dosage. Ophthalmologic Surgical Procedures. Prognosis. Risk Factors. Treatment Outcome

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  • (PMID = 24844033.001).
  • [ISSN] 1220-0875
  • [Journal-full-title] Oftalmologia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Oftalmologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Ophthalmic Solutions
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15. Cooper IF, Siadaty MS: 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; Hormone;ConjunctivalNeoplasm:705146923. ISSN: 2331-5717. 2014/3/22
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  • [Title] 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Hormone' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Hormone'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 15 publications, and group two 2241 publications.
  • Here are the top 9.
  • Chance B: A case exhibiting a symblepharon, corneal opacities and a probably fibro-fatty tumor of the conjunctiva, all of pre-natal origin, in a woman with hereditary cataracts at an early age.
  • Feng G et al: [777 cases of the primary conjunctival neoplasms].
  • Ozcan AA et al: Topical mitomycin C for the treatment of conjunctival tumor.
  • Furdová A et al: [The TNM classification system in malignant conjunctival neoplasms].
  • Yeatts RP et al: Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea.
  • Margo CE et al: Borderline melanocytic tumor of the conjunctiva: diagnostic and therapeutic considerations.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Margo CE et al: Intraepithelial neoplasia of the conjunctiva with mucoepidermoid differentiation.
  • Pe'er J et al: Solitary fibrous tumor of the conjunctiva.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705146923.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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16. Cooper IF, Siadaty MS: 'Qualitative Concepts' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; QualitativeConcept;ConjunctivalNeoplasm:706186862. ISSN: 2331-5717. 2014/12/24
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  • [Title] 'Qualitative Concepts' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Qualitative Concept' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Qualitative Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 11 publications, and group two 1457 publications.
  • Here are the top 6.
  • Cooper IF et al: 'Steroids' associated with 'Conjunctival Neoplasm': Top Publications.
  • Ranjbar M et al: [Prominent conjunctival tumor].
  • Rodriguez-Sains RS: Pigmented conjunctival neoplasms.
  • Domeier E et al: [Sudden appearance of conjunctival tumor in a 7-year-old boy].
  • Chen HC et al: Adjunctive treatment with interferon alpha-2b may decrease the risk of papilloma-associated conjunctival intraepithelial neoplasm recurrence.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706186862.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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17. Cooper IF, Siadaty MS: 'Steroids' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; Steroid;ConjunctivalNeoplasm:705526978. ISSN: 2331-5717. 2014/6/22
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  • [Title] 'Steroids' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Steroid' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Steroid'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 15 publications, and group two 2229 publications.
  • Here are the top 9.
  • Chance B: A case exhibiting a symblepharon, corneal opacities and a probably fibro-fatty tumor of the conjunctiva, all of pre-natal origin, in a woman with hereditary cataracts at an early age.
  • Feng G et al: [777 cases of the primary conjunctival neoplasms].
  • Ozcan AA et al: Topical mitomycin C for the treatment of conjunctival tumor.
  • Furdová A et al: [The TNM classification system in malignant conjunctival neoplasms].
  • Yeatts RP et al: Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea.
  • Margo CE et al: Borderline melanocytic tumor of the conjunctiva: diagnostic and therapeutic considerations.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Margo CE et al: Intraepithelial neoplasia of the conjunctiva with mucoepidermoid differentiation.
  • Pe'er J et al: Solitary fibrous tumor of the conjunctiva.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705526978.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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18. 'Phosphorus 32 Brachytherapy Regime Therapy': Top Publications. BioMedLib Review OC; ;Phosphorus32Brachytherapy:710371488. ISSN: 2331-5717. 2015/9/19; updates online.
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  • [Title] 'Phosphorus 32 Brachytherapy Regime Therapy': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'phosphorus 32 brachytherapy regime therapy'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 3 publications, and group two 11 publications.
  • Here is the first one.
  • Tong WY et al: Intraoperative phosphorus-32 brachytherapy plaque for multiply recurrent high-risk epidural neuroblastoma.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710371488.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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19. 'Phosphorus 32 Brachytherapy': Top Publications. BioMedLib Review OC; ;Phosphorus32Brachytherapy:708276533. ISSN: 2331-5717. 2015/4/19; updates online.
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  • [Title] 'Phosphorus 32 Brachytherapy': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'phosphorus 32 brachytherapy'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 5 publications, and group two 112 publications.
  • Here are the top 3.
  • Tong WY et al: Intraoperative phosphorus-32 brachytherapy plaque for multiply recurrent high-risk epidural neuroblastoma.
  • DeNittis AS et al: Complete remission of nonresectable pancreatic cancer after infusional colloidal phosphorus-32 brachytherapy, external beam radiation therapy, and 5-fluorouracil: a preliminary report.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 708276533.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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20. 'Conjunctival Tumor': Top Publications. BioMedLib Review OC; ;ConjunctivalTumor:710007573. ISSN: 2331-5717. 2015/10/12; updates online.
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  • [Title] 'Conjunctival Tumor': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'conjunctival tumor'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 124 publications, and group two 628 publications.
  • Here are the top 6.
  • Cooper IF et al: 'Qualitative Concepts' associated with 'Conjunctival Neoplasm': Top Publications.
  • Cooper IF et al: 'Neoplastic Processes' associated with 'Conjunctival Neoplasm': Top Publications.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • Sivkova N et al: Malignant melanoma of the conjunctiva – successful surgical excision of the primary tumor and reconstruction by conjunctival auto transplantation from the contralateral eye.
  • Chen HM et al: Localized peripheral primitive neuroectodermal tumor of the conjunctiva: a rare presentation.
  • Cooper IF et al: 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710007573.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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21. Cinotti E, Perrot JL, Labeille B, Campolmi N, Espinasse M, Grivet D, Thuret G, Gain P, Douchet C, Andrea C, Haouas M, Cambazard F: Handheld reflectance confocal microscopy for the diagnosis of conjunctival tumors. Am J Ophthalmol; 2015 Feb;159(2):324-33.e1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Handheld reflectance confocal microscopy for the diagnosis of conjunctival tumors.
  • PURPOSE: To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of conjunctival tumors.
  • METHODS: We prospectively evaluated the reflectance confocal microscopy features of 53 conjunctival lesions clinically suspicious for tumors of 46 patients referred to the University Hospital of Saint-Etienne (France) by using the handheld device.
  • Clinical reflectance confocal microscopy and histologic diagnosis were compared.
  • RESULTS: In vivo reflectance confocal microscopy diagnosis was in agreement with the histologic diagnosis in all cases and none of the lesions that were not excised show any clinical progression under follow-up.
  • CONCLUSION: In vivo reflectance confocal microscopy with a handheld dermatology-dedicated microscope can play a role in the noninvasive diagnosis of conjunctival lesions.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Microscopy, Confocal
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / diagnosis. Female. Humans. Lymphoma / diagnosis. Male. Melanoma / diagnosis. Middle Aged. Nevus / diagnosis. Prospective Studies. Young Adult

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  • [Copyright] Copyright © 2015 Elsevier Inc. All rights reserved.
  • (PMID = 25447117.001).
  • [ISSN] 1879-1891
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article; Observational Study
  • [Publication-country] United States
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22. Gómez-García S, Marcuello-Melendo B, Torres-Gómez FJ: [Oncocytoma of the caruncle: a case report]. Arch Soc Esp Oftalmol; 2013 Jul;88(7):276-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Oncocitoma de la carúncula: caso clínico.
  • CASE REPORT: We describe a 79 year-old woman who had a small lesion on the inner corner of her right eye for the last 6 months.
  • The lesion was surgically excised and histologically analysed, with a diagnosis of oncocytoma of the caruncle.
  • DISCUSSION: Ocular oncocytomas are rare benign neoplasms found in the caruncle, conjunctiva, lacrimal gland and lacrimal sac.
  • Although rare, this tumour should be recognized especially in the elderly because of the exceptional development of adenocarcinoma.
  • [MeSH-major] Adenoma, Oxyphilic. Conjunctival Neoplasms

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  • [Copyright] Copyright © 2011 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.
  • (PMID = 23768476.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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23. 'Conjunctiva Of The Tumor': Top Publications. BioMedLib Review OC; ;ConjunctivaOfThe:710007620. ISSN: 2331-5717. 2015/7/12; updates online.
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  • [Title] 'Conjunctiva Of The Tumor': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'conjunctiva of the tumor'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 124 publications, and group two 448 publications.
  • Here are the top 6.
  • Cooper IF et al: 'Ideas or Concepts' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • Chen HM et al: Localized peripheral primitive neuroectodermal tumor of the conjunctiva: a rare presentation.
  • Cooper IF et al: 'Geographic Areas' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Cooper IF et al: 'Eicosanoids' associated with 'Malignant Conjunctiva Neoplasm': Top Publications.
  • Sivkova N et al: Malignant melanoma of the conjunctiva – successful surgical excision of the primary tumor and reconstruction by conjunctival auto transplantation from the contralateral eye.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710007620.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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24. 'Tumor Of The Conjunctiva': Top Publications. BioMedLib Review OC; ;TumorOfThe:707923895. ISSN: 2331-5717. 2015/6/12; updates online.
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  • [Title] 'Tumor Of The Conjunctiva': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'tumor of the conjunctiva'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 124 publications, and group two 448 publications.
  • Here are the top 6.
  • Cooper IF et al: 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications.
  • Chen HM et al: Localized peripheral primitive neuroectodermal tumor of the conjunctiva: a rare presentation.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • Cooper IF et al: 'Ideas or Concepts' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Cooper IF et al: 'Intellectual Products' associated with 'Malignant Conjunctiva Neoplasm': Top Publications.
  • Sivkova N et al: Malignant melanoma of the conjunctiva – successful surgical excision of the primary tumor and reconstruction by conjunctival auto transplantation from the contralateral eye.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707923895.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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25. 'Phosphorus Toxicity': Top Publications. BioMedLib Review OC; ;PhosphorusToxicity:710569723. ISSN: 2331-5717. 2015/8/23; updates online.
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  • [Title] 'Phosphorus Toxicity': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'phosphorus toxicity'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 17 publications, and group two 683 publications.
  • Here are the top 7.
  • Lakshmi CP et al: Cholestatic presentation of yellow phosphorus poisoning.
  • Cooper IF et al: 'Injuries or Poisonings' associated with 'Phosphorus Poisoning': Top Publications.
  • Cooper IF et al: 'Functional Concepts' associated with 'Phosphorus Poisoning': Top Publications.
  • Cooper IF et al: 'Organophosphorus Compounds' associated with 'Phosphorus Poisoning': Top Publications.
  • Marr BP et al: Intraoperative high-dose rate of radioactive phosphorus 32 brachytherapy for diffuse recalcitrant conjunctival neoplasms: a retrospective case series and report of toxicity.
  • Cheng W et al: [Toxicity and treatment strategies of phosphorus oxychloride].
  • Wang NX et al: Effects of nitrogen and phosphorus on arsenite accumulation, oxidation, and toxicity in Chlamydomonas reinhardtii.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 710569723.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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26. Liu WW, Lin JY, Yu XH: [Clinical and histopathological features of conjunctival myxoma and angiomyxoma]. Zhonghua Yan Ke Za Zhi; 2012 Nov;48(11):981-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical and histopathological features of conjunctival myxoma and angiomyxoma].
  • OBJECTIVE: To explore the clinical and pathological features of conjunctival myxoma and angiomyxoma.
  • The clinical and pathological features of 3 cases of conjunctival myxoma and 2 cases of conjunctival angiomyxoma were analyzed.
  • These cases were treated from January 2005 to December 2010 at Tianjin Eye Hospital.
  • The tumors presented as yellow-pink, translucent, cystic and(or) with solid masses.
  • Regarding the tumor location, 2 cases involved the temporal side, 1 case involved the nasal side, 1 case involved the nasal limbus and invaded the cornea, and 1 case involved the nasal, temporal and inferior parts.
  • Histopathological examination revealed that the conjunctival myxomas were composed of abundant mucoid material and relatively small numbers of small, ovoid, spindle and stellate shaped cells with sparse vessels.
  • The histologic features of the conjunctival angiomyxoma were similar to those of myxomas with the exception of the former being characterized by a prominent vascular structure.
  • The immunohistochemical staining showed that tumor cells were positive for Vimentin, but negative for S-100 protein; some tumor cells were positive for CD34 and SMA.
  • CONCLUSIONS: Most of the conjunctival myxoma and angiomyxoma appear as a local yellow-pink, translucent, cystic and(or) with solid mass, and some of which had multiple tumors.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Myxoma / pathology

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  • (PMID = 23302270.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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27. Kimura K, Usui Y, Goto H: [Clinical findings and prognosis of 11 cases of conjunctival malignant melanoma]. Nihon Ganka Gakkai Zasshi; 2012 May;116(5):503-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical findings and prognosis of 11 cases of conjunctival malignant melanoma].
  • PURPOSE: To describe the clinical findings and prognosis of conjunctival malignant melanomas.
  • SUBJECTS: We investigated the clinical findings and prognosis of 11 cases of conjunctival malignant melanomas diagnosed and treated at Tokyo Medical University Hospital.
  • Cases arose from primary acquired melanosis (PAM) in 45% of the patients, from conjunctival nevus in 9%, from both conjunctival nevus and PAM in 27% and de novo in 18%.
  • In all cases local resection was performed with either adjuvant cryotherapy, or similar methods for diagnosis and treatment.
  • Total surgical excision of the tumor was performed for recurrent lesions.
  • CONCLUSION: A combination of surgical excision with adjuvant therapy has been used for the treatment of conjunctival melanoma.
  • [MeSH-major] Conjunctival Neoplasms. Melanoma
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Prognosis. Treatment Outcome

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  • (PMID = 22690541.001).
  • [ISSN] 0029-0203
  • [Journal-full-title] Nippon Ganka Gakkai zasshi
  • [ISO-abbreviation] Nippon Ganka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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28. Yumori JW, Ilsen P, Bright DC: Conjunctival plasmacytoma. Optometry; 2010 May;81(5):234-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival plasmacytoma.
  • BACKGROUND: Plasmacytomas are plasma cell tumors that may be a primary or secondary tumor focus, the latter of which are associated with multiple myeloma.
  • We present a rare case of a solitary extramedullary plasmacytoma involving the conjunctiva.
  • CASE REPORT: A 33-year-old white man presented with the initial complaint of redness in both eyes, more in his right than left eye.
  • A vascularized conjunctival lesion was noted in his right eye.
  • The patient underwent excisional biopsy, which found a conjunctival plasmacytoma.
  • CONCLUSION: Although plasmacytomas of the eye and orbit are rare, it is important to be familiar with these tumors that may be associated with multiple myeloma.
  • Definitive diagnosis is made by biopsy and histopathologic examination of the tissue.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Plasmacytoma / diagnosis
  • [MeSH-minor] Adult. Biopsy. Conjunctiva / pathology. Humans. Male

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  • [Copyright] Copyright 2010 American Optometric Association. All rights reserved.
  • (PMID = 20435269.001).
  • [ISSN] 1558-1527
  • [Journal-full-title] Optometry (St. Louis, Mo.)
  • [ISO-abbreviation] Optometry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Kaliki S, Arepalli S, Shields CL, Klein K, Sun H, Hysenj E, Lally SE, Shields JA: Conjunctival papilloma: features and outcomes based on age at initial examination. JAMA Ophthalmol; 2013 May;131(5):585-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival papilloma: features and outcomes based on age at initial examination.
  • IMPORTANCE: Conjunctival papilloma is a benign epithelial tumor occurring in both children and adults with varying clinical features and outcomes.
  • In this article, we describe our experience regarding the difference in the clinical features and outcomes of conjunctival papilloma based on age at initial examination.
  • OBJECTIVE: To evaluate the clinical features, treatment, and outcomes in patients with conjunctival papilloma based on age at initial examination.
  • SETTING: Ocular Oncology Service, Wills Eye Hospital, Philadelphia, Pennsylvania.
  • PARTICIPANTS: Ten children and adolescents (aged ≤20 years) and 63 adults (aged >20 years) with conjunctival papilloma.
  • MAIN OUTCOME MEASURE: Tumor response.
  • RESULTS: A comparison of conjunctival papillomas between age groups revealed significant differences in the mean number of tumors per eye (children and adolescents vs adults, 2 vs 1; P = .05), tumor basal dimension (8 vs 6 mm; P = .05), and associated feeder vessels (20% vs 47%; P = .05).
  • Significant differences in age groups in treatment outcome during the follow-up period (mean, 24 vs 38 months) included complete regression with single treatment (38% vs 95%; P < .01) and tumor recurrence (15% vs 1%; P = .05).
  • CONCLUSIONS AND RELEVANCE: Conjunctival papillomas are larger and more likely to be multiple in children and adolescents than in adults.
  • Excisional biopsy and cryotherapy with or without adjuvant oral cimetidine and/or topical interferon alfa-2b provide satisfactory tumor control.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Papilloma / pathology

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  • (PMID = 23538642.001).
  • [ISSN] 2168-6173
  • [Journal-full-title] JAMA ophthalmology
  • [ISO-abbreviation] JAMA Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Immunologic Factors; 0 / Interferon-alpha; 0 / Recombinant Proteins; 80061L1WGD / Cimetidine; 99210-65-8 / interferon alfa-2b
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30. Kheirkhah A, Mahbod M, Farzbod F, Zavareh MK, Behrouz MJ, Hashemi H: Repeated applications of impression cytology to increase sensitivity for diagnosis of conjunctival intraepithelial neoplasia. Br J Ophthalmol; 2012 Feb;96(2):229-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Repeated applications of impression cytology to increase sensitivity for diagnosis of conjunctival intraepithelial neoplasia.
  • PURPOSE: To increase sensitivity of impression cytology (IC) for the diagnosis of conjunctival intraepithelial neoplasia (CIN) by three repeated applications of IC.
  • METHODS: This study included 35 eyes with a clinical diagnosis of CIN and 6 eyes with pinguecula as control.
  • The sensitivity of each application of IC for the diagnosis of CIN was determined.
  • CONCLUSION: Consecutive repeated applications of filter paper significantly increased the diagnostic sensitivity of IC for the diagnosis of CIN.
  • [MeSH-major] Carcinoma in Situ / diagnosis. Conjunctival Neoplasms / diagnosis. Diagnostic Techniques, Ophthalmological

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  • (PMID = 21498806.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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31. Jandroković S, Popović-Suić S, Mandić JJ, Kuzman T, Skegro I, Kutija MB, Masnec S, Kalauz M: Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma. Coll Antropol; 2014 Dec;38(4):1187-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma.
  • Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion.
  • We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM.
  • The disease was too extensive for ocular conservation, therefore exenteration was performed.
  • This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma / diagnosis. Melanosis / pathology
  • [MeSH-minor] Aged. Disease Progression. Female. Humans

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  • (PMID = 25842754.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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32. Mudhar HS, Rennie IG: Local conjunctival metastases from primary conjunctival melanoma: clinico-pathological correlation and implications. Br J Ophthalmol; 2013 Jan;97(1):33-9
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  • [Title] Local conjunctival metastases from primary conjunctival melanoma: clinico-pathological correlation and implications.
  • BACKGROUND/AIMS: A retrospective service evaluation identified seven patients who developed local conjunctival metastases (LCMs) of the conjunctiva after a primary diagnosis of conjunctival invasive melanoma.
  • METHODS: Seven patients with primary conjunctival melanoma seen by the ocular oncology service were identified as having also developed LCMs.
  • The clinical history, histopathology, tumour biology, prognostic and staging implications of LCMs were evaluated.
  • RESULTS: A total of 15 primary conjunctival melanomas and 19 LCMs were identified.
  • The LCM developed 8-102 months after the first primary melanoma and, in three patients, non-conjunctival metastases developed 8-37 months after the first LCM.
  • CONCLUSIONS: LCMs are local metastases of primary conjunctival melanoma that probably develop by dissemination through the local vessels and then becoming extavascular.
  • Their accurate histopathological recognition is important, as it indicates a higher disease stage-indicating 'N' status within the TNM classification and may be a proxy indicator of the presence of non-conjunctival metastases, thus necessitating high-resolution radiological imaging modalities or sentinel node biopsy.
  • LCMs may represent an under-recognised lesion and may have been mistaken for primary 'nodular' conjunctival melanomas in the past.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Melanoma / secondary. Neoplasms, Second Primary / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Retrospective Studies. Time Factors

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  • (PMID = 23143907.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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33. Herwig MC, Fischer HP, Holz FG, Loeffler KU: [Conjunctival myxoma: two cases. Histopathological examination and clinical course]. Ophthalmologe; 2010 Sep;107(9):843-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Conjunctival myxoma: two cases. Histopathological examination and clinical course].
  • Conjunctival myxoma is a rare and benign tumour without tendency for recurrence.
  • Removal of each tumour was followed by histopathological examination including immunohistochemistry as well as electron microscopy.
  • Besides the expected findings characteristic of conjunctival myxoma some features reflecting the possible aetiology of this entity are shown.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Conjunctival Neoplasms / surgery. Myxoma / pathology. Myxoma / surgery

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  • (PMID = 20376460.001).
  • [ISSN] 1433-0423
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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34. Litak J, Dimitropoulos VA, Dy LC, Brown CW, Grostern RJ: Conjunctival papilloma. Cutis; 2012 Jan;89(1):38-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival papilloma.
  • Conjunctival papillomas are some of the most common tumors of the conjunctiva and are well-described in ophthalmology textbooks.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Papilloma / pathology

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  • (PMID = 22439310.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. 'Cytopathology Technique Filter Method': Top Publications. BioMedLib Review CN; ;CytopathologyTechniqueFilter:709749441. ISSN: 2331-5717. 2015/4/8; updates online.
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  • [Title] 'Cytopathology Technique Filter Method': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'cytopathology technique filter method'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 7 publications.
  • Here are the top 4.
  • Obata H et al: [New membrane filter (PORETEC) method for ocular diagnostic cytopathology].
  • Schumann GB et al: Semiquantitative approach to CSF cytopathology.
  • Iijima J et al: Usefulness of Auto Cyto Fix (membrane filter method) for the application of immunohistochemistry.
  • Kabbani W et al: Cell block findings from residual PreservCyt samples in unsatisfactory ThinPrep Paps: no additional benefit.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709749441.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review CN
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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36. 'Referral To Medical Physics Service': Top Publications. BioMedLib Review CN; ;ReferralToMedical:709003684. ISSN: 2331-5717. 2015/4/10; updates online.
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  • [Title] 'Referral To Medical Physics Service': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'referral to medical physics service'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 6 publications.
  • Here are the top 3.
  • Vano E et al: Patient radiation dose management in the follow-up of potential skin injuries in neuroradiology.
  • Walsh C et al: Synchronized, interactive teleconferencing with digital cardiac images.
  • Martin CJ: A survey of incidents in radiology and nuclear medicine in the West of Scotland.

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 709003684.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review CN
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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37. 'Cryotherapy Of Eyelid': Top Publications. BioMedLib Review OC; ;CryotherapyOfEyelid:708761115. ISSN: 2331-5717. 2015/3/14; updates online.
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  • [Title] 'Cryotherapy Of Eyelid': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'cryotherapy of eyelid'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 13 publications, and group two 167 publications.
  • Here are the top 7.
  • Matthäus W et al: [Cryotherapy of eyelid and conjunctival tumors].
  • Buschmann W et al: [Technique and results of nitrogen cryotherapy of eyelid basaliomas].
  • Anders M et al: [Cryotherapy of malignant eyelid tumors].
  • Fraunfelder FT et al: Results of cryotherapy for eyelid malignancies.
  • Buschmann W et al: [Current results of nitrogen cryotherapy in eyelid basaliomas].
  • Shin YS et al: A randomised controlled trial of the effects of cryotherapy on pain, eyelid oedema and facial ecchymosis after craniotomy.
  • Imachi J et al: [Cryotherapy of tumors of the eyelid].

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  • [Copyright] Copyright 2015 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 708761115.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review OC
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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38. Shildkrot Y, Wilson MW: Conjunctival melanoma: pitfalls and dilemmas in management. Curr Opin Ophthalmol; 2010 Sep;21(5):380-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Conjunctival melanoma: pitfalls and dilemmas in management.
  • PURPOSE OF REVIEW: The current dilemmas in the diagnosis and management of conjunctival melanoma are reviewed in this paper.
  • Available evidence for the role of sentinel lymph node biopsy as it applies to conjunctival melanoma is examined.
  • RECENT FINDINGS: The incidence of conjunctival melanoma appears to be on the rise.
  • Analyses of 770 patients with conjunctival melanoma reveals a nearly 50% rate of local recurrence, and up to a 38% 10-year mortality.
  • SUMMARY: The management of conjunctival surface melanomas is complicated by local recurrence and metastatic disease, particularly for lesions greater than 2 mm in thickness and arising from nonbulbar conjunctiva.
  • Conjunctival anatomy and high recurrence rate with resultant metastatic spread undermines the utility of sentinel lymph node biopsy in this condition.
  • Further research and innovation for detection of systemic micrometastases and treatment of metastatic disease are needed.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Conjunctival Neoplasms / therapy. Melanoma / diagnosis. Melanoma / therapy
  • [MeSH-minor] Antibiotics, Antineoplastic / administration & dosage. Cryotherapy. Humans. Lymphatic Metastasis. Mitomycin / administration & dosage. Neoplasm Recurrence, Local. Sentinel Lymph Node Biopsy

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  • (PMID = 20531189.001).
  • [ISSN] 1531-7021
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 50SG953SK6 / Mitomycin
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39. Salazar Méndez R, Baamonde Arbaiza B, de la Roz Martín P, Parra Rodríguez T: [Treatment of conjunctival melanoma]. Arch Soc Esp Oftalmol; 2014 Feb;89(2):82-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of conjunctival melanoma].
  • [Transliterated title] Tratamiento del melanoma conjuntival.
  • CLINICAL CASE: The cases of an 86 year-old woman and a 61 year-old man with conjunctival pigmented tumors are presented.
  • An excisional biopsy, conjunctival cryotherapy and amniotic membrane grafts were performed in both cases, along with the application of mitomycin-C in the postoperative period.
  • DISCUSSION: The recommended treatment for conjunctival melanoma is surgical removal with adjunctive therapies such as cryotherapy or topical mitomycin-C.
  • [MeSH-major] Conjunctival Neoplasms / surgery. Melanoma / surgery

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  • HSDB. MITOMYCIN C .
  • HSDB. MITOMYCIN C .
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  • [Copyright] Copyright © 2011 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.
  • (PMID = 24269405.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 50SG953SK6 / Mitomycin
  • [Keywords] NOTNLM ; Amniotic membrane / Biopsia / Biopsy / Cirugía / Conjunctival melanoma / Melanoma conjuntival / Membrana amniótica / Mitomicina C / Mitomycin-C / Surgery
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40. Rankin JK, Jakobiec FA, Zakka FR, Foster CS: An improved approach to diagnosing and treating conjunctival mucoepidermoid carcinoma. Surv Ophthalmol; 2012 Jul-Aug;57(4):337-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An improved approach to diagnosing and treating conjunctival mucoepidermoid carcinoma.
  • The current case of conjunctival mucoepidermoid carcinoma offers features that expand the biologic spectrum afforded by this tumor.
  • More focused strategies should be developed for its earlier histopathologic diagnosis and improved management (historical recurrence rate of 85%).
  • Behaviorally aggressive or rapidly recurrent epithelial squamous tumors with "inflammatory" features or unusual clinical characteristics should be initially stained at multiple levels for the detection of parsimonious mucus secretion.
  • [MeSH-major] Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / surgery. Conjunctival Neoplasms / diagnosis. Conjunctival Neoplasms / surgery
  • [MeSH-minor] Carcinoma, Squamous Cell / chemistry. Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Eye Enucleation. Female. Humans. Middle Aged. Neoplasm Invasiveness. Tumor Markers, Biological / analysis

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  • [Copyright] Copyright © 2012 Elsevier Inc. All rights reserved.
  • (PMID = 22541742.001).
  • [ISSN] 1879-3304
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Markers, Biological
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41. Lee A, Li EY, Yuen HK: Inferonasal prolapsed orbital fat: report of a case and review of literature. Ophthal Plast Reconstr Surg; 2013 Jul-Aug;29(4):e110-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It can be confused with other conjunctival tumors.
  • [MeSH-major] Adipose Tissue / pathology. Conjunctival Neoplasms / pathology

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  • (PMID = 23392315.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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42. Jakobiec FA, Werdich XQ, Chodosh J, Freitag SK: An analysis of conjunctival and periocular venous malformations: clinicopathologic and immunohistochemical features with a comparison of racemose and cirsoid lesions. Surv Ophthalmol; 2014 Mar-Apr;59(2):236-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An analysis of conjunctival and periocular venous malformations: clinicopathologic and immunohistochemical features with a comparison of racemose and cirsoid lesions.
  • Vascular tumors (in contrast to dilations or ectasias) of the conjunctiva and other adnexal tissues are rare, with no previous convincing example of a congenital, purely venous conjunctival malformation having been described.
  • A 33-year-old man with a previously well-tolerated racemose conjunctival lesion present from birth developed bothersome symptoms when it underwent multifocal thrombosis with papillary endothelial cell hyperplasia as part of the process of thrombotic organization.
  • [MeSH-major] Eye Neoplasms / pathology. Vascular Malformations / pathology
  • [MeSH-minor] Adult. Conjunctival Neoplasms / pathology. Humans. Male

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  • [Copyright] Copyright © 2014 Elsevier Inc. All rights reserved.
  • (PMID = 24355066.001).
  • [ISSN] 1879-3304
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Keywords] NOTNLM ; arteriovenous malformation / cirsoid hemangioma / conjunctiva / hemorrhagic lymphangiectasia / immunohistochemistry / racemose hemangioma / varix / venous angioma / venous malformation
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43. Hwang SS, Kim JE, Chun BK, Jung S, Park EK, Lee HJ, Jung M, Lee SJ, Noh GM, Masanganise R, Oak C, Ahn YC: New model of subconjunctival tumor development in rabbits. J Biomed Opt; 2013 Jul;18(7):070501
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New model of subconjunctival tumor development in rabbits.
  • Conjunctival squamous cell carcinoma (SCC) is an uncommon disease.
  • However, basic research concerning SCC, including both intraepithelial and invasive squamous neoplasia, is limited due to the lack of an ocular tumor animal model.
  • Specifically, current ocular imaging and treatment modalities are insufficient for investigating currently available small animal models, because the conjunctival space is not comparable to that of humans.
  • Malignant tumor involvement developed on the subconjunctival space after an average of 1 to 2 weeks.
  • This subconjunctival tumor model induction method will likely facilitate a broad range of investigation of subconjunctival cancer diagnostics and therapeutics.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Disease Models, Animal
  • [MeSH-minor] Animals. Cell Line, Tumor. Conjunctiva / pathology. Male. Neoplasm Transplantation. Rabbits. Tomography, Optical Coherence

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  • (PMID = 23817759.001).
  • [ISSN] 1560-2281
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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44. Shields JA, Kligman BE, Mashayekhi A, Shields CL: Acquired sessile hemangioma of the conjunctiva: a report of 10 cases. Am J Ophthalmol; 2011 Jul;152(1):55-59.e1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acquired sessile hemangioma of the conjunctiva: a report of 10 cases.
  • PURPOSE: To report 10 cases of an unusual conjunctival lesion that has been termed acquired sessile hemangioma.
  • METHODS: A chart review was conducted on patients coded as having a conjunctival vascular tumor at the Ocular Oncology Service at Wills Eye Institute, Thomas Jefferson University.
  • A cohort of these patients was identified as having a lesion comprising a complex sessile arrangement of conjunctival blood vessels that were remarkably similar to one another, but were distinctly different from other known conjunctival vascular tumors and malformations.
  • These lesions were called acquired sessile hemangioma of the conjunctiva.
  • Each tumor was assessed for anatomic location in the conjunctiva, quadrant of involvement, diameter, thickness, margin (sharp or ill-defined), and presence of feeder blood vessels.
  • The median age at the time of diagnosis was 58 years (mean, 58 years; range, 31-83 years).
  • In the other 9 cases, it was a coincidental finding by the authors on referral for unrelated problems.
  • In each case, acquired sessile hemangioma was characterized by a flat array of intertwining, mildly dilated blood vessels, usually on the bulbar conjunctiva.
  • CONCLUSIONS: Acquired sessile hemangioma is an unusual conjunctival vascular lesion of adults that has characteristic clinical features.
  • It should be differentiated from other conjunctival vascular lesions.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Hemangioma, Capillary / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Conjunctiva / blood supply. Conjunctiva / pathology. Female. Fluorescein Angiography. Humans. Male. Middle Aged. Retrospective Studies

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  • [Copyright] Copyright © 2011 Elsevier Inc. All rights reserved.
  • (PMID = 21529766.001).
  • [ISSN] 1879-1891
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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45. Parrozzani R, Lazzarini D, Dario A, Midena E: In vivo confocal microscopy of ocular surface squamous neoplasia. Eye (Lond); 2011 Apr;25(4):455-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In vivo confocal microscopy of ocular surface squamous neoplasia.
  • PURPOSE: To analyse in vivo structural and cellular features of ocular surface squamous neoplasia using clinical confocal microscopy.
  • METHODS: Ten consecutive cases of untreated ocular surface squamous neoplasia were in vivo investigated using clinical confocal microscopy (ConfoScan4, Nidek Co.
  • RESULTS: Confocal microscopy examination revealed large areas of superficial cells debris and/or keratin debris accompanied by syncytial-like groupings, loss of the normal structure of the conjunctival epithelium and or of the corneal basal epithelium layer, papillomatous organization, large fibrovascular structures, and fine vessels perpendicular to the tumour surface.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Microscopy, Confocal

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  • [Cites] Br J Ophthalmol. 2000 Mar;84(3):268-72 [10684836.001]
  • [Cites] Br J Ophthalmol. 2011 Mar;95(3):355-9 [20693564.001]
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  • (PMID = 21311574.001).
  • [ISSN] 1476-5454
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3171251
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46. Carvalho RM, Taleb A, Carvalho GL, Avila M: [Conjunctival fibrous histiocytoma simulating atipical pterygium in the Amazon region: case report]. Arq Bras Oftalmol; 2010 Nov-Dec;73(6):534-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Conjunctival fibrous histiocytoma simulating atipical pterygium in the Amazon region: case report].
  • [Transliterated title] Fibrohistiocitoma conjuntival simulando pterígio atípico na região amazônica: relato de caso.
  • An inedited case in the Brazilian literature of conjunctival fibrous histiocytoma discovered during a wide scale community project accomplished by the team of the Center of Reference in Ophthalmology of the Hospital das Clínicas da Universidade Federal de Goiás in the Amazon region is reported.
  • A 38 year-old caucasian woman presented with a vascularized lesion on the medial portion of the bulbar conjunctiva and caruncular region of the right eye with extension for the limbus and invading about 2 mm of the medial cornea resembling a pterygium.
  • The histopathologic diagnosis was fibrous histiocytoma.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Pterygium / pathology
  • [MeSH-minor] Adult. Brazil. Diagnosis, Differential. Female. Humans

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  • (PMID = 21271031.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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47. Shields CL, Kaliki S, Al-Dahmash SA, Lally SE, Shields JA: American Joint Committee on Cancer (AJCC) clinical classification predicts conjunctival melanoma outcomes. Ophthal Plast Reconstr Surg; 2012 Sep-Oct;28(5):313-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] American Joint Committee on Cancer (AJCC) clinical classification predicts conjunctival melanoma outcomes.
  • PURPOSE: The aim of this study was to evaluate conjunctival melanoma outcomes based on American Joint Committee on Cancer classification.
  • RESULTS: On the basis of the American Joint Committee on Cancer classification (seventh edition), conjunctival melanoma was classified as T1 (196 [57%]), T2 (110 [32%]), T3 (37 [11%]), and T4 (0).
  • The mean tumor basal diameter increased with tumor staging with 8.5 mm for T1, 12.7 mm for T2 (p = 0.0003), and 16 mm for T3 (p < 0.0001).
  • The melanoma arose from primary acquired melanosis (T1 = 71%; T2 = 84%; T3 = 81%), preexisting nevus (T1 = 8%; T2 = 5%; T3 = 3%), or de novo (T1 = 21%; T2 = 12%; T3 = 16%).
  • Outcomes at 5 years (Kaplan-Meier) revealed melanoma local recurrence/new tumor in 44% T1, 78% T2 (p < 0.0001), and 76% T3 (P=0.0044); regional lymph node metastasis in 17% T1, 52% T2 (p < 0.0001), and 49% T3 (p = 0.0092); melanoma-related distant metastasis in 11% T1, 35% T2 (p < 0.0001), and 42% T3 (p = 0.0018); and melanoma-related death in 5% T1, 20% T2 (p = 0.0655), and 23% T3 (p = 0.0526).
  • After adjusting for tumor origin, factors predictive of regional lymph node metastasis, melanoma-related distant metastasis, and melanoma-related death included melanoma arising de novo (p < 0.0001; p < 0.0001; p < 0.0001), T2 stage (p < 0.0001; p < 0.0001; p = 0.007), and T3 stage (p = 0.005; p = 0.0014; p = 0.0342).
  • CONCLUSION: The American Joint Committee on Cancer staging predicts prognosis of conjunctival melanoma.
  • [MeSH-major] Conjunctival Neoplasms / classification. Conjunctival Neoplasms / pathology. Melanoma / classification. Melanoma / secondary
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphatic Metastasis. Male. Medical Oncology / organization & administration. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Retrospective Studies. Risk Factors. Survival Rate. United States. Young Adult


48. Giuri S, Raica M, Munteanu M: Myxoid/round cell conjunctival liposarcoma. A case report. Rom J Morphol Embryol; 2013;54(3):655-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoid/round cell conjunctival liposarcoma. A case report.
  • PURPOSE: To present a rare case of conjunctival myxoid liposarcoma, subtype round cells, that had a seven years follow up.
  • CLINICAL OBSERVATION: A 61-year-old female patient presents with a palpable, non-painful tumor, on the superior temporal bulbar conjunctiva of the right eye.
  • The initial examination detects a fleshy tumor, orange in color, under the superior temporal bulbar conjunctiva, as well as two oval-shaped hyperpigmented conjunctival lesions, near the limbus at 10 o'clock, causing moderate blepharoptosis.
  • An isolated 15/15 mm tumor, with no connections with the eye socket, was excised.
  • The last two rapidly evolving and large recurrences, as well as pulmonary metastasis and finally death of the patient, underlined the aggressive character of round cell conjunctival liposarcoma.
  • CONCLUSIONS: Conjunctival myxoid liposarcoma is characterized by numerous local recurrences, but the speed of the succession and volume of the recurrences may suggest a change in the underlying histopathological aspect, that is definitory for the therapeutical and prognostic approach of the case.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Liposarcoma, Myxoid / pathology

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  • (PMID = 24068420.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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49. Artornsombudh P, Sanpavat A, Tinnungwattana U, Tongkhomsai V, Sansopha L, Tulvatana W: Prevalence and clinicopathologic findings of conjunctival epithelial neoplasia in pterygia. Ophthalmology; 2013 Jul;120(7):1337-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevalence and clinicopathologic findings of conjunctival epithelial neoplasia in pterygia.
  • PURPOSE: To study the prevalence of conjunctival neoplasia in clinically diagnosed pterygia and the clinicopathologic characteristics of conjunctival tissues obtained from pterygium excision.
  • PARTICIPANTS: From February through August 2007, consecutive subjects indicated for pterygium excision were enrolled from an outpatient eye clinic of King Chulalongkorn Memorial Hospital, Bangkok, Thailand, and from the eye camp at the 6th Station of the Thai Red Cross Society, Aranyaprathet District, Sa Kaeo, Thailand.
  • Histopathologic results showed that 4 eyes had conjunctival intraepithelial neoplasia.
  • Two eyes had minimal cellular atypia at the conjunctival epithelium.
  • For the subjects who had conjunctival epithelial neoplasia, the mean age was 57.0 ± 8.0 years, 44.4% were male, and none had a history of carcinoma in other organs or any history of herpes virus, human papilloma virus, or human immunodeficiency virus infections.
  • CONCLUSIONS: The prevalence of conjunctival epithelial neoplasia in clinically diagnosed pterygia is approximately 1.8%.
  • Because the clinical characteristics of subjects who have conjunctival epithelial neoplasia apparently did not differ from those without, tissue pathologic examination may be required to diagnose the condition.
  • [MeSH-major] Carcinoma in Situ / epidemiology. Conjunctival Neoplasms / epidemiology. Pterygium / complications

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  • [Copyright] Copyright © 2013 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.
  • (PMID = 23499063.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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50. Bellido Muñoz RM, Domínguez Hidalgo I, García Serrano JL, López Peña C: [Immunohistochemical markers in the diagnosis of pigmented conjunctival lesions]. Arch Soc Esp Oftalmol; 2012 Apr;87(4):119-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Immunohistochemical markers in the diagnosis of pigmented conjunctival lesions].
  • [Transliterated title] Utilidad de marcadores inmunohistoquímicos para el diagnóstico de lesiones pigmentadas conjuntivales.
  • OBJECTIVE/METHOD: The aim of this study was to assess the importance of immunohistochemical markers in the diagnosis of pigmented conjunctival lesions.
  • Due to the difficulty of making an exact clinical diagnosis, the suspicion of malignancy requires the removal of the lesion and performing a histopathology study in which immunohistochemical markers may help to determine the nature of the lesion.
  • However, after carrying out immunohistochemical markers the diagnosis was conjunctival compound nevus.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Nevus, Pigmented / diagnosis
  • [MeSH-minor] Antigens, CD / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Diagnosis, Differential. Female. Humans. MART-1 Antigen / analysis. Melanoma / diagnosis. Melanoma-Specific Antigens / analysis. Tumor Markers, Biological. Young Adult

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  • [Copyright] Copyright © 2010 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.
  • (PMID = 22482895.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / HMB-45 protein, human; 0 / MART-1 Antigen; 0 / Melanoma-Specific Antigens; 0 / Tumor Markers, Biological
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