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1. Biomedical articles (top 50; 2009 to 2014)
1. ||||||.... 57%  Moloney TP, Trinh T, Farrah JJ: A case of conjunctival mucoepidermoid carcinoma in Australia. Clin Ophthalmol; 2014;8:11-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of conjunctival mucoepidermoid carcinoma in Australia.
  • Conjunctival mucoepidermoid carcinoma is a very rare but highly aggressive conjunctival neoplasm with 42 previously reported cases.
  • We report the case of a 56-year-old male with a left ocular surface squamous neoplasm, which was subsequently treated with excision and autoconjunctival graft.
  • Histopathology of the operative specimen reported a low-grade conjunctival mucoepidermoid carcinoma, and the patient was then treated with an adjunctive course of mitomycin C.
  • Due to its rare incidence, difficult clinical diagnosis, and accompanying poor prognosis, conjunctival mucoepidermoid carcinoma should always be considered in the differential diagnosis of conjunctival neoplasms, and full histopathologic examination, including mucin-staining techniques, of all suspicious conjunctival biopsies should occur.

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  • (PMID = 24363552.001).
  • [ISSN] 1177-5467
  • [Journal-full-title] Clinical ophthalmology (Auckland, N.Z.)
  • [ISO-abbreviation] Clin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3862775
  • [Keywords] NOTNLM ; conjunctiva / mitomycin C / neoplasm / pterygium
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2. |||||..... 46%  Saornil MA, Becerra E, Méndez MC, Blanco G: [Conjunctival tumors]. Arch Soc Esp Oftalmol; 2009 Jan;84(1):7-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Conjunctival tumors].
  • [Transliterated title] Tumores de la conjuntiva.
  • Conjunctival tumors are one of the most frequent of the eye and adnexa.
  • In this paper we review the clinical characteristics of the most frequent conjunctival tumors, and we discuss tumor management.
  • [MeSH-major] Conjunctival Neoplasms
  • [MeSH-minor] Carcinoma / pathology. Carcinoma / surgery. Conjunctival Diseases / pathology. Conjunctival Diseases / surgery. Eye Enucleation. Eye Evisceration. Hematologic Neoplasms / pathology. Hematologic Neoplasms / surgery. Humans. Melanoma / pathology. Melanoma / surgery. Neoplasm Invasiveness. Nevus / pathology. Nevus / surgery. Papilloma / pathology. Papilloma / surgery. Precancerous Conditions / pathology. Precancerous Conditions / surgery. Sarcoma / pathology. Sarcoma / surgery

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  • (PMID = 19173134.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 47
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3. |||....... 34%  Levy-Gabriel C: [Suspicious conjunctival lesions]. J Fr Ophtalmol; 2010 Feb;33(2):125-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Suspicious conjunctival lesions].
  • [Transliterated title] Taches suspectes de la conjonctive.
  • The main conjunctival tumors are represented by (i) conjunctival melanoma, ocular surface squamous neoplasia, and conjunctival lymphoma, which are malignant tumors, and (ii) conjunctival nevus, papilloma, and choristoma, which are benign.
  • In usual practice, ophthalmologists need to know how to differentiate conjunctival melanomas and carcinomas from the other conjunctival tumors by clinical examination.
  • Indeed, the therapeutic approach to these two malignant diseases presents a number of particularities such as the need for surgery under general anesthesia, if possible, to minimize the risk of local dissemination and further local recurrence, and detailed information on the tumor location and measurements before surgery (Figures, diagram, sizes) to precisely define the irradiation field during complementary radiotherapy.
  • The clinical signs and main therapeutic principles of conjunctival tumors are reviewed in this article.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Conjunctival Neoplasms / therapy. Ophthalmology / methods
  • [MeSH-minor] Choristoma / diagnosis. Combined Modality Therapy. Diagnosis, Differential. Humans. Lymphoma / diagnosis. Melanoma / diagnosis. Neoplasm Staging. Neoplasms, Squamous Cell / diagnosis. Nevus / diagnosis. Papilloma / diagnosis. Pigmentation. Precancerous Conditions / diagnosis

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20096479.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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4. ||||...... 44%  Cooper IF, Siadaty MS: 'Neoplastic Processes' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; NeoplasticProcess;ConjunctivalNeoplasm:706156063. ISSN: 2331-5717. 2014/12/23
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  • [Title] 'Neoplastic Processes' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Neoplastic Process' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Neoplastic Process'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 27 publications, and group two 1502 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Steroids' associated with 'Benign Conjunctiva Neoplasm': Top Publications.
  • Ranjbar M et al: [Prominent conjunctival tumor].
  • Chen Z et al: Amniotic membrane transplantation for conjunctival tumor.
  • Pe'er J et al: Solitary fibrous tumor of the conjunctiva.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Tuncer S et al: Regression of conjunctival tumor during dietary treatment of celiac disease.
  • Kim JW et al: Topical treatment options for conjunctival neoplasms.
  • Matsuo T et al: Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm.
  • Yeatts RP et al: 5-Fluorouracil for the treatment of intraepithelial neoplasia of the conjunctiva and cornea.
  • Rodriguez-Sains RS: Pigmented conjunctival neoplasms.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706156063.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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5. |||||..... 49%  Maschi C, Caujolle JP, Liolios I, Costet C: [Benign conjunctival tumors]. J Fr Ophtalmol; 2013 Nov;36(9):796-802
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign conjunctival tumors].
  • [Transliterated title] Tumeurs conjonctivales bénignes.
  • Benign conjunctival tumors include congenital, melanocytic, epithelial and stromal lesions.
  • Onco-ophthalmologists must have a perfect knowledge of benign conjunctival tumors, since during adulthood, nevi can be confused with melanomas, and epithelial or stromal lesions with carcinomas.
  • [MeSH-major] Conjunctival Neoplasms
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / pathology. Adolescent. Adult. Humans. Keratoacanthoma / diagnosis. Keratoacanthoma / pathology. Melanoma / diagnosis. Melanoma / pathology. Neoplasms, Nerve Tissue / diagnosis. Neoplasms, Nerve Tissue / pathology. Neoplasms, Vascular Tissue / diagnosis. Neoplasms, Vascular Tissue / pathology. Nevus, Pigmented / diagnosis. Nevus, Pigmented / pathology

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  • [Copyright] Copyright © 2013 Elsevier Masson SAS. All rights reserved.
  • (PMID = 24099696.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Keywords] NOTNLM ; Congenital tumors / Conjonctive / Conjunctiva / Epithelial tumors / Melanocytic tumors / Stromal tumors / Tumeurs congénitales / Tumeurs mélaniques / Tumeurs stromales / Tumeurs épithéliales
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6. ||||...... 45%  Cooper IF, Siadaty MS: 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications. BioMedLib Review; Hormone;ConjunctivalNeoplasm:705146923. ISSN: 2331-5717. 2014/3/22
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  • [Title] 'Hormones' associated with 'Conjunctival Neoplasm': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Hormone' for 'conjunctival neoplasm'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Hormone'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 15 publications, and group two 2241 publications.
  • Here are the top 9.
  • Chance B: A case exhibiting a symblepharon, corneal opacities and a probably fibro-fatty tumor of the conjunctiva, all of pre-natal origin, in a woman with hereditary cataracts at an early age.
  • Feng G et al: [777 cases of the primary conjunctival neoplasms].
  • Ozcan AA et al: Topical mitomycin C for the treatment of conjunctival tumor.
  • Furdová A et al: [The TNM classification system in malignant conjunctival neoplasms].
  • Yeatts RP et al: Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea.
  • Margo CE et al: Borderline melanocytic tumor of the conjunctiva: diagnostic and therapeutic considerations.
  • Favini F et al: Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.
  • Margo CE et al: Intraepithelial neoplasia of the conjunctiva with mucoepidermoid differentiation.
  • Pe'er J et al: Solitary fibrous tumor of the conjunctiva.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705146923.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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7. |||....... 29%  Alves LF, Fernandes BF, Burnier JV, Zoroquiain P, Eskenazi DT, Burnier Jr MN: Incidence of epithelial lesions of the conjunctiva in a review of 12,102 specimens in Canada (Quebec). Arq Bras Oftalmol; 2011 Jan-Feb;74(1):21-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence of epithelial lesions of the conjunctiva in a review of 12,102 specimens in Canada (Quebec).
  • PURPOSE: The purpose of this study was to assess the relative frequency of epithelial lesions of the conjunctiva in Canada.
  • The relative frequency of epithelial lesions of the conjunctiva from a single center in Canada, representing the province of Quebec was reviewed.
  • RESULTS: Of the 12,102 specimens reviewed, 273 were conjunctival lesions (2.25%), including 86 epithelial tumors (0.71%) of the conjunctiva that comprised the studied sample.
  • Within the ocular surface squamous neoplasia (OSSN) spectrum, there were 10 (11.6%) actinic keratosis (63.8 ± 17.6 years), 27 (31.3%) cases of conjunctival intraepithelial neoplasia (CIN) with variable degrees of atypia (mild to moderate) (63.9 ± 15.3 years), 15 (17.4%) carcinomas in situ (66.7 ± 18.0 years), and 17 (19.7%) squamous cell carcinomas (SCC) (56.2 ± 19.4 years).
  • Two other rare cases of malignant tumors included one basal cell carcinoma and one mucoepidermoid carcinoma.
  • When we compare our sample to others coming from countries with high levels of sunlight exposure, we found a lower incidence of ocular surface squamous neoplasia, including squamous cell carcinomas in Canada.
  • [MeSH-major] Conjunctival Neoplasms / epidemiology

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  • (PMID = 21670902.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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8. |||....... 26%  Parrozzani R, Lazzarini D, Dario A, Midena E: In vivo confocal microscopy of ocular surface squamous neoplasia. Eye (Lond); 2011 Apr;25(4):455-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In vivo confocal microscopy of ocular surface squamous neoplasia.
  • PURPOSE: To analyse in vivo structural and cellular features of ocular surface squamous neoplasia using clinical confocal microscopy.
  • METHODS: Ten consecutive cases of untreated ocular surface squamous neoplasia were in vivo investigated using clinical confocal microscopy (ConfoScan4, Nidek Co.
  • RESULTS: Confocal microscopy examination revealed large areas of superficial cells debris and/or keratin debris accompanied by syncytial-like groupings, loss of the normal structure of the conjunctival epithelium and or of the corneal basal epithelium layer, papillomatous organization, large fibrovascular structures, and fine vessels perpendicular to the tumour surface.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Microscopy, Confocal

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  • (PMID = 21311574.001).
  • [ISSN] 1476-5454
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3171251
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9. |||||..... 47%  Özcan AA, Çiloğlu E, Esen E, Şimdivar GH: Use of topical bevacizumab for conjunctival intraepithelial neoplasia. Cornea; 2014 Nov;33(11):1205-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of topical bevacizumab for conjunctival intraepithelial neoplasia.
  • PURPOSE: To report our experience in the treatment of intraepithelial neoplasia of the conjunctiva using topical bevacizumab.
  • METHODS: Ten eyes of 10 patients with conjunctival neoplasia received 25 mg/mL bevacizumab topically.
  • The size and vascularity of the tumors reduced weekly.
  • CONCLUSIONS: Topical bevacizumab is an effective treatment to reduce the tumor size before surgery and may be a good alternative for adjuvant therapy