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1. Biomedical articles (top 50; 2009 to 2014)
1. |||||||||. 100%  Ienaga K, Hum Park C, Yokozawa T: Daily hydroxyl radical scavenging capacity of mammals. Drug Discov Ther; 2014 Apr;8(2):71-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Daily hydroxyl radical scavenging capacity of mammals.
  • Both the formation and reactions of hydroxyl radical (•OH) are quantitative chemical reactions even in mammalians, and so we can reproduce such in vivo reactions in test tubes.
  • Daily urinary excretions of some reaction products have been used to estimate the amount of •OH produced daily.
  • Although urinary 8-hydroxydeoxyguanosine (8-OHdG) is a well-known marker of •OH, we have shown that creatol (CTL: 5-hydroxycreatinine), an •OH adduct of creatinine (Crn), and its metabolite, methylguanidine (MG), are better markers, because the amount of •OH scavenged by deoxyguanosine (dG) in the body is negligible.
  • We measured CTL and MG together with Crn in 24-h urine, and calculated their molar sum, CTL + MG, providing a daily estimate of moles of •OH scavenged with Crn, and, from the molar ratio (CTL + MG)/Crn, we can calculate the percentage of Crn that was used to scavenge •OH.
  • ) 0.2 and 0.3% of Crn in order to scavenge •OH, respectively, because the corresponding ratios, scavenged •OH/Crn, were 2.2 and 3.0 mmole/mole (24-h urine) (Crn scavenged ca.
  • 200 pmole of •OH in healthy subjects and normal rats, respectively).
  • In patients with chronic renal failure (CRF) or chronic kidney disease (CKD) at stages 3-5: glomerular filtration rate (GFR) < 60 mL/min/1.73 m(2), •OH levels increased in proportion to the severity of CKD: up to ca.
  • 3% of Crn was used daily in order to scavenge •OH.
  • Although the accumulation of MG in organs has not been reported except for the brain and skin tissues in normal animals, •OH increases markedly and MG becomes detectable in all organs such as the kidney, liver, and heart in CRF rats.
  • [MeSH-major] Free Radical Scavengers / metabolism. Hydroxyl Radical / metabolism. Kidney / metabolism. Kidney Failure, Chronic / metabolism

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  • (PMID = 24815581.001).
  • [ISSN] 1881-7831
  • [Journal-full-title] Drug discoveries & therapeutics
  • [ISO-abbreviation] Drug Discov Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biological Markers; 0 / Free Radical Scavengers; 133882-98-1 / creatol; 3352-57-6 / Hydroxyl Radical; 5L0H5Q9VAG / Methylguanidine; 88847-89-6 / 8-oxo-7-hydrodeoxyguanosine; AYI8EX34EU / Creatinine; G9481N71RO / Deoxyguanosine
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2. |||||||||. 87%  Kielpinski LJ, Vinther J: Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility. Nucleic Acids Res; 2014 Apr;42(8):e70
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  • [Title] Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility.
  • Hydroxyl Radical Footprinting (HRF) is a tried-and-tested method for analysis of the tertiary structure of RNA and for identification of protein footprints on RNA.
  • The hydroxyl radical reaction breaks accessible parts of the RNA backbone, thereby allowing ribose accessibility to be determined by detection of reverse transcriptase termination sites.
  • Here, we describe an accurate and efficient massive parallel-sequencing-based method for probing RNA accessibility with hydroxyl radicals, called HRF-Seq.
  • [MeSH-major] High-Throughput Nucleotide Sequencing / methods. Hydroxyl Radical. RNA / chemistry. Sequence Analysis, RNA / methods

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  • (PMID = 24569351.001).
  • [ISSN] 1362-4962
  • [Journal-full-title] Nucleic acids research
  • [ISO-abbreviation] Nucleic Acids Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / RNA, Ribosomal, 16S; 3352-57-6 / Hydroxyl Radical; 63231-63-0 / RNA; EC 3.1.26.5 / Ribonuclease P
  • [Other-IDs] NLM/ PMC4005689
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3. |||||||||. 87%  Ding F, Lavender CA, Weeks KM, Dokholyan NV: Three-dimensional RNA structure refinement by hydroxyl radical probing. Nat Methods; 2012 Jun;9(6):603-8
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  • [Title] Three-dimensional RNA structure refinement by hydroxyl radical probing.
  • Hydroxyl radical probing (HRP), which is performed routinely in many laboratories, provides a measure of solvent accessibility at individual nucleotides.
  • [MeSH-major] Hydroxyl Radical / chemistry. RNA / ultrastructure

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  • (PMID = 22504587.001).
  • [ISSN] 1548-7105
  • [Journal-full-title] Nature methods
  • [ISO-abbreviation] Nat. Methods
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA084480; United States / NIGMS NIH HHS / GM / GM064803; United States / NIGMS NIH HHS / GM / GM080742; United States / NIGMS NIH HHS / GM / R01 GM064803
  • [Publication-type] Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 3352-57-6 / Hydroxyl Radical; 63231-63-0 / RNA; 9014-25-9 / RNA, Transfer
  • [Other-IDs] NLM/ NIHMS397905; NLM/ PMC3422565
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4. |||||||||. 100%  Cooper IF, Siadaty MS: 'Hormones' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Hormone;HydroxylRadical:705397129. ISSN: 2331-5717. 2014/4/25
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  • [Title] 'Hormones' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Hormone' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Hormone'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 26 publications, and group two 17344 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Hormones' associated with 'Hydroxyl Radical': Top Publications.
  • Kobayashi Y et al: Passive ultrasonic irrigation in the presence of a low concentration of hydrogen peroxide enhances hydroxyl radical generation and bactericidal effect against Enterococcus faecalis.
  • Górska AM et al: The effect of caffeine on MDMA-induced hydroxyl radical production in the mouse striatum.
  • Shannon RJ et al: Accelerated chemistry in the reaction between the hydroxyl radical and methanol at interstellar temperatures facilitated by tunnelling.
  • Passananti M et al: The impact of the hydroxyl radical photochemical sources on the rivastigmine drug transformation in mimic and natural waters.
  • Kim MK et al: Effects of natural water constituents on the photo-decomposition of methylmercury and the role of hydroxyl radical.
  • Drouin BJ: Isotopic spectra of the hydroxyl radical.
  • Seal P et al: Kinetics of the hydrogen atom abstraction reactions from 1-butanol by hydroxyl radical: theory matches experiment and more.
  • Kaur G et al: Exploring water catalysis in the reaction of thioformic Acid with hydroxyl radical: a global reaction route mapping perspective.
  • Vu ND et al: Absolute rate coefficient of the gas-phase reaction between hydroxyl radical (OH) and hydroxyacetone: investigating the effects of temperature and pressure.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705397129.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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5. |||||||||. 98%  Cooper IF, Siadaty MS: 'Bacteriums' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Bacterium;HydroxylRadical:705536058. ISSN: 2331-5717. 2014/4/29
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  • [Title] 'Bacteriums' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Bacterium' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Bacterium'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 21 publications, and group two 46864 publications.
  • Here are the top 10.
  • McCormick ML et al: Endogenous superoxide dismutase levels regulate iron-dependent hydroxyl radical formation in Escherichia coli exposed to hydrogen peroxide.
  • Scarlett DJ et al: Mapping functionally important motifs SPF and GGQ of the decoding release factor RF2 to the Escherichia coli ribosome by hydroxyl radical footprinting. Implications for macromolecular mimicry and structural changes in RF2.
  • Morimitsu Y et al: Ansamycin antibiotics as free radical scavengers isolated from Streptomyces by using the bactericidal action of the hydroxyl radical.
  • Nunoshiba T et al: Role of iron and superoxide for generation of hydroxyl radical, oxidative DNA lesions, and mutagenesis in Escherichia coli.
  • Hryniewicz MM et al: Hydroxyl radical footprints and half-site arrangements of binding sites for the CysB transcriptional activator of Salmonella typhimurium.
  • Sampson TR et al: Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway.
  • Huycke MM et al: In vivo production of hydroxyl radical by Enterococcus faecalis colonizing the intestinal tract using aromatic hydroxylation.
  • Kim AY et al: Radiation-induced cell lethality of Salmonella typhimurium ATCC 14028: cooperative effect of hydroxyl radical and oxygen.
  • Zhang S et al: Electron spin resonance studies on photosensitized formation of hydroxyl radical by C-phycocyanin from Spirulina platensis.
  • Brandi G et al: Cytocidal and filamentous response of Escherichia coli cells exposed to low concentrations of hydrogen peroxide and hydroxyl radical scavengers.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705536058.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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6. ||||||||.. 85%  Lipinski B: Hydroxyl radical and its scavengers in health and disease. Oxid Med Cell Longev; 2011;2011:809696
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hydroxyl radical and its scavengers in health and disease.
  • On the other hand, important biomolecules can be modified by the introduction of oxygen atoms by means of non-oxidative hydroxyl radicals.
  • In addition, hydroxyl radicals can reduce disulfide bonds in proteins, specifically fibrinogen, resulting in their unfolding and scrambled refolding into abnormal spatial configurations.
  • It is described in this paper that hydroxyl radicals can be generated by ferric ions without any oxidizing agent.
  • However, beneficial effects of the great number of phytochemicals that are endowed with hydroxyl radical scavenging and/or iron chelating activities should not be considered as a proof for oxidative stress.
  • [MeSH-major] Free Radical Scavengers / metabolism. Hydroxyl Radical / metabolism. Oxidative Stress / physiology

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  • (PMID = 21904647.001).
  • [ISSN] 1942-0994
  • [Journal-full-title] Oxidative medicine and cellular longevity
  • [ISO-abbreviation] Oxid Med Cell Longev
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Free Radical Scavengers; 3352-57-6 / Hydroxyl Radical
  • [Other-IDs] NLM/ PMC3166784
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7. |||||||||. 86%  Kiselar JG, Chance MR: Future directions of structural mass spectrometry using hydroxyl radical footprinting. J Mass Spectrom; 2010 Dec;45(12):1373-82
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  • [Title] Future directions of structural mass spectrometry using hydroxyl radical footprinting.
  • Hydroxyl radical protein footprinting coupled to mass spectrometry has been developed over the last decade and has matured to a powerful method for analyzing protein structure and dynamics.
  • In this review, we describe a new application of hydroxyl radical protein footprinting to probe the time evolution of the calcium-dependent conformational changes of gelsolin on the millisecond timescale.
  • The hydroxyl radical varies in its reactivity to different side chains by over two orders of magnitude, thus oxidation of amino acid side chains of lower reactivity are more rarely observed in such experiments.
  • [MeSH-major] Hydroxyl Radical / chemistry. Mass Spectrometry / methods. Peptide Mapping / methods. Proteins / chemistry

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  • [Copyright] Copyright © 2010 John Wiley & Sons, Ltd.
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  • (PMID = 20812376.001).
  • [ISSN] 1096-9888
  • [Journal-full-title] Journal of mass spectrometry : JMS
  • [ISO-abbreviation] J Mass Spectrom
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / P30 EB009998; United States / NIBIB NIH HHS / EB / P30 EB009998-01; United States / NIBIB NIH HHS / EB / P30-EB-09998; United States / NIBIB NIH HHS / EB / R01 EB009688; United States / NIBIB NIH HHS / EB / R01 EB009688-01A1; United States / NIBIB NIH HHS / EB / R01-EB-09688
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proteins; 3352-57-6 / Hydroxyl Radical
  • [Other-IDs] NLM/ NIHMS228301; NLM/ PMC3012749
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8. |||||||||. 86%  San Pedro JM, Greenberg MM: Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine. Org Lett; 2012 Jun 1;14(11):2866-9
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  • [Title] Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine.
  • 5,6-Dihydro-5-hydroxythymidin-6-yl radical (1), the major reactive intermediate resulting from hydroxyl radical addition to C5 of the pyrimidine, is produced via 350 nm photolysis of a 2,5-dimethoxyphenylsulfide precursor (2).
  • Competition between O(2) and thiol for 1 suggests that the radical reacts relatively slowly with β-mercaptoethanol compared to other alkyl radicals.
  • Overall, aryl sulfide 2 should be an effective precursor for the major hydroxyl radical adduct of thymidine in DNA.
  • [MeSH-major] Hydroxyl Radical / chemistry. Thymidine / analogs & derivatives. Thymidine / chemistry

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  • (PMID = 22616940.001).
  • [ISSN] 1523-7052
  • [Journal-full-title] Organic letters
  • [ISO-abbreviation] Org. Lett.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM-054996; United States / NIGMS NIH HHS / GM / R01 GM054996
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 5,6-dihydro-5-hydroxythymidin-6-yl radical; 3352-57-6 / Hydroxyl Radical; 9007-49-2 / DNA; VC2W18DGKR / Thymidine
  • [Other-IDs] NLM/ NIHMS379655; NLM/ PMC3366351
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9. |||||||||. 103%  Gardner JM, Aust SD: Quantification of hydroxyl radical produced during phacoemulsification. J Cataract Refract Surg; 2009 Dec;35(12):2149-53
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  • [Title] Quantification of hydroxyl radical produced during phacoemulsification.
  • PURPOSE: To quantitate hydroxyl radicals produced during phacoemulsification with various irrigating solutions and conditions used in cataract surgery.
  • Hydroxyl radicals were quantitated using electron spin resonance spectroscopy and a spectrophotometric assay for malondialdehyde, which is formed by the oxidation of deoxyribose by the hydroxyl radical.
  • RESULTS: Hydroxyl radical production increased during longitudinal-stroking phacoemulsification as power levels were increased in a nonlinear, nonexponential fashion.
  • The detection of hydroxyl radical was reduced in irrigating solutions containing organic molecules (eg, citrate, acetate, glutathione, dextrose) and further reduced in Navstel, an irrigating solution containing a viscosity-modifying agent, hydroxypropyl methylcellulose.
  • CONCLUSIONS: Hydroxyl radicals produced in settings representative of those used in phacoemulsification cataract surgery were quantitated using the deoxyribose method.
  • Hydroxyl radical production was dependent on the level of ultrasound power applied and the irrigating solution used.
  • Oxidative stress on the eye during phacoemulsification may be minimized by using irrigating solutions that contain organic molecules, including the viscosity-modifying agent hydroxypropyl methylcellulose, that can compete for reaction with hydroxyl radicals.
  • [MeSH-major] Acetates. Bicarbonates. Glutathione. Hydroxyl Radical / analysis. Minerals. Phacoemulsification. Sodium Chloride. Water

  • MedlinePlus Health Information. consumer health - Minerals.
  • HSDB. structure - MALONALDEHYDE.
  • HSDB. structure - SODIUM CHLORIDE.
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  • (PMID = 19969222.001).
  • [ISSN] 1873-4502
  • [Journal-full-title] Journal of cataract and refractive surgery
  • [ISO-abbreviation] J Cataract Refract Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acetates; 0 / BSS solution; 0 / Bicarbonates; 0 / Drug Combinations; 0 / Minerals; 0 / glutathione-bicarbonate-Ringer solution; 059QF0KO0R / Water; 3352-57-6 / Hydroxyl Radical; 4Y8F71G49Q / Malondialdehyde; 7647-14-5 / Sodium Chloride; GAN16C9B8O / Glutathione
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10. |||||||||. 102%  Jagannathan I, Hayes JJ: Hydroxyl radical footprinting of protein-DNA complexes. Methods Mol Biol; 2009;543:57-71
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  • [Title] Hydroxyl radical footprinting of protein-DNA complexes.
  • This unit details the use of hydroxyl radicals to characterize protein-DNA interactions.
  • We describe several methods to prepare DNA templates for footprinting and ways to avoid many of the pitfalls associated with the use of hydroxyl radical footprinting.
  • [MeSH-major] DNA / metabolism. DNA Footprinting / methods. Hydroxyl Radical / metabolism. MutS Homolog 2 Protein / metabolism

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  • (PMID = 19378159.001).
  • [ISSN] 1064-3745
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM052426
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 3352-57-6 / Hydroxyl Radical; 9007-49-2 / DNA; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
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11. |||||||||. 102%  Bisby RH, Crisostomo AG, Botchway SW, Parker AW: Nanoscale hydroxyl radical generation from multiphoton ionization of tryptophan. Photochem Photobiol; 2009 Jan-Feb;85(1):353-7
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  • [Title] Nanoscale hydroxyl radical generation from multiphoton ionization of tryptophan.
  • The resulting hydrated electron is scavenged by hydrogen peroxide to produce the hydroxyl radical.
  • The involvement of hydroxyl radicals is confirmed by the use of ethanol and nitrous oxide as scavengers and their effects on the fluorescence yield in this system.
  • [MeSH-major] Hydroxyl Radical / chemistry. Photons

  • HSDB. structure - (L)-TRYPTOPHAN.
  • HSDB. structure - HYDROGEN PEROXIDE.
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  • (PMID = 19161400.001).
  • [ISSN] 0031-8655
  • [Journal-full-title] Photochemistry and photobiology
  • [ISO-abbreviation] Photochem. Photobiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Solutions; 3352-57-6 / Hydroxyl Radical; 8DUH1N11BX / Tryptophan; BBX060AN9V / Hydrogen Peroxide
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12. |||||||||. 102%  Costa M, Monachello D: Probing RNA folding by hydroxyl radical footprinting. Methods Mol Biol; 2014;1086:119-42
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  • [Title] Probing RNA folding by hydroxyl radical footprinting.
  • Among available experimental tools to investigate the higher-order folding of structured RNAs, hydroxyl radical probing stands as one of the most informative and reliable ones.
  • Hydroxyl radicals are oxidative species that cleave the nucleic acid backbone solely according to the solvent accessibility of individual phosphodiester bonds, with no sequence or secondary structure specificity.
  • In this chapter we describe a robust, accurate and very sensitive hydroxyl radical probing method that can be applied to any structured RNA molecule and is suitable to investigate RNA folding and RNA conformational changes induced by binding of a ligand.
  • [MeSH-major] Hydroxyl Radical / metabolism. RNA / chemistry. RNA Folding

  • HSDB. structure - ETHYLENEDIAMINE TETRAACETIC ACID.
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  • (PMID = 24136601.001).
  • [ISSN] 1940-6029
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Ferrous Compounds; 3352-57-6 / Hydroxyl Radical; 63231-63-0 / RNA; 9G34HU7RV0 / Edetic Acid
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13. |||||||||. 102%  Patra PK, Krol MC, Montzka SA, Arnold T, Atlas EL, Lintner BR, Stephens BB, Xiang B, Elkins JW, Fraser PJ, Ghosh A, Hintsa EJ, Hurst DF, Ishijima K, Krummel PB, Miller BR, Miyazaki K, Moore FL, Mühle J, O'Doherty S, Prinn RG, Steele LP, Takigawa M, Wang HJ, Weiss RF, Wofsy SC, Young D: Observational evidence for interhemispheric hydroxyl-radical parity. Nature; 2014 Sep 11;513(7517):219-23
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  • [Title] Observational evidence for interhemispheric hydroxyl-radical parity.
  • The hydroxyl radical (OH) is a key oxidant involved in the removal of air pollutants and greenhouse gases from the atmosphere.
  • The ratio of Northern Hemispheric to Southern Hemispheric (NH/SH) OH concentration is important for our understanding of emission estimates of atmospheric species such as nitrogen oxides and methane.
  • Here we determine the NH/SH ratio of OH with the help of methyl chloroform data (a proxy for OH concentrations) and an atmospheric transport model that accurately describes interhemispheric transport and modelled emissions.
  • We find that for the years 2004-2011 the model predicts an annual mean NH-SH gradient of methyl chloroform that is a tight linear function of the modelled NH/SH ratio in annual mean OH.
  • We estimate a NH/SH OH ratio of 0.97 ± 0.12 during this time period by optimizing global total emissions and mean OH abundance to fit methyl chloroform data from two surface-measurement networks and aircraft campaigns.
  • Our findings suggest that top-down emission estimates of reactive species such as nitrogen oxides in key emitting countries in the NH that are based on a NH/SH OH ratio larger than 1 may be overestimated.
  • [MeSH-major] Atmosphere / chemistry. Hydroxyl Radical / chemistry. Models, Theoretical

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  • [CommentIn] Nature. 2014 Sep 11;513(7517):176-8 [25209794.001]
  • (PMID = 25209800.001).
  • [ISSN] 1476-4687
  • [Journal-full-title] Nature
  • [ISO-abbreviation] Nature
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Air Pollutants; 0 / Nitrogen Oxides; 3352-57-6 / Hydroxyl Radical; 7V31YC746X / Chloroform
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14. |||||||||. 101%  Yang XL, Bai MD, Han F: [Rapid elimination of surface organophosphorous pollutants using hydroxyl radical]. Huan Jing Ke Xue; 2010 Jun;31(6):1670-4
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  • [Title] [Rapid elimination of surface organophosphorous pollutants using hydroxyl radical].
  • According to the frequency of contamination accident for organic compounds in recent years, two kinds of organophosphorus pesticides dichlorvos and omethoate, as the simulated organic pollutants, were rapidly eliminated using spraying hydroxyl radical produced by strong electric-field ionization discharge method on an aluminium flat plate about 160 cm2.
  • The high concentration aqueous *OH solution was produced from H2O(gas) and O2 with plasma reaction.
  • In a condition, where pH is 6 and the initial densities of dichlorvos and omethoate on the simulation plane are both 60 microg x cm(-2), when the spray density of *OH reaches 3.9 microg x cm-2, removal efficiencies of dichlorvos and omethoate are 90%, and mineralization rates are 64% and 72%, respectively.
  • Four factors and three levels orthogonal test indicated that the degradation by *OH played a major role at the surface oxidation removal rapid of organophosphorus pollutants in a short period of time.
  • [MeSH-major] Environmental Pollutants / isolation & purification. Hydroxyl Radical / chemistry. Organophosphorus Compounds / isolation & purification

  • HSDB. structure - OMETHOATE.
  • HSDB. structure - DIMETHOATE.
  • HSDB. structure - DICHLORVOS.
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  • (PMID = 20698288.001).
  • [ISSN] 0250-3301
  • [Journal-full-title] Huan jing ke xue= Huanjing kexue / [bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui "Huan jing ke xue" bian ji wei yuan hui.]
  • [ISO-abbreviation] Huan Jing Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Environmental Pollutants; 0 / Insecticides; 0 / Organophosphorus Compounds; 1113-02-6 / dimethoxon; 3352-57-6 / Hydroxyl Radical; 7U370BPS14 / Dichlorvos; W6U08B045O / Dimethoate
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15. |||||||||. 91%  Li L, Goel RK: Role of hydroxyl radical during electrolytic degradation of contaminants. J Hazard Mater; 2010 Sep 15;181(1-3):521-5
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  • [Title] Role of hydroxyl radical during electrolytic degradation of contaminants.
  • The role of hydroxyl radical is investigated in electrochemical oxidation of organic contaminants with naphthalene as a model compound.
  • The strategy employed was competitive kinetic for hydroxyl radical between naphthalene and other hydroxyl scavengers if the hydroxyl radical is produced in situ at the anode by the electrolysis of water.
  • Methanol, d3-methanol, acetone and d6-acetone were used as competitors for hydroxyl radical and their molar concentrations were calculated based on their reaction constants with hydroxyl radical.
  • The hydroxyl radical was not responsible for naphthalene loss in these experiments.
  • Rate constants using methanol and d6-methanol as competitors for hydroxyl radical in batch degradations test were 0.128 and 0.099 h(-1), respectively.
  • Based on the naphthalene degradation trends and reaction rate constants, it was concluded that, under the given set of conditions, hydroxyl radical was not responsible for naphthalene degradation during electrolytic degradation tests.
  • This research suggests that the role of hydroxyl radical should be considered very carefully in modeling such indirect electrolytic oxidation processes.
  • [MeSH-major] Environmental Remediation / methods. Hydroxyl Radical / chemistry. Organic Chemicals / chemistry. Water Pollutants, Chemical / chemistry

  • HSDB. structure - NAPHTHALENE.
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  • [Copyright] Published by Elsevier B.V.
  • (PMID = 20580488.001).
  • [ISSN] 1873-3336
  • [Journal-full-title] Journal of hazardous materials
  • [ISO-abbreviation] J. Hazard. Mater.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Naphthalenes; 0 / Organic Chemicals; 0 / Water Pollutants, Chemical; 2166IN72UN / naphthalene; 3352-57-6 / Hydroxyl Radical
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16. |||||||||. 98%  Cooper IF, Siadaty MS: 'Chemicals' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Chemical;HydroxylRadical:706656312. ISSN: 2331-5717. 2014/12/29
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  • [Title] 'Chemicals' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Chemical' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Chemical'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 26 publications, and group two 16722 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Nucleic Acids, Nucleosides, or Nucleotides' associated with 'Hydroxyl Radical': Top Publications.
  • Gómez Alvarez E et al: Unexpectedly high indoor hydroxyl radical concentrations associated with nitrous acid.
  • Christiansen CJ et al: Hydroxyl radical substitution in halogenated carbonyls: oxalic acid formation.
  • Lü JM et al: Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid.
  • Preis S et al: Pulsed corona discharge: the role of ozone and hydroxyl radical in aqueous pollutants oxidation.
  • Milne L et al: Comparison of hydroxyl radical formation in aqueous solutions at different ultrasound frequencies and powers using the salicylic acid dosimeter.
  • Jørgensen S et al: The gas-phase reaction of methane sulfonic acid with the hydroxyl radical without and with water vapor.
  • Li Y et al: Interactive enhancements of ascorbic acid and iron in hydroxyl radical generation in quinone redox cycling.
  • Vel Leitner NK et al: Kinetic of benzotriazole oxidation by ozone and hydroxyl radical.
  • Biard PF et al: Intensification of volatile organic compounds mass transfer in a compact scrubber using the O3/H2O2 advanced oxidation process: kinetic study and hydroxyl radical tracking.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706656312.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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17. |||||||||. 98%  Cooper IF, Siadaty MS: 'Receptors' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Receptor;HydroxylRadical:705432084. ISSN: 2331-5717. 2014/4/28
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  • [Title] 'Receptors' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Receptor' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Receptor'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 18 publications, and group two 25293 publications.
  • Here are the top 10.
  • Gołembiowska K et al: Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum.
  • Cooper IF et al: 'Receptors' associated with 'Hydroxyl Radical': Top Publications.
  • Kao TY et al: Aspirin may exert its antipyresis by inhibiting the N-methyl-D-aspartate receptor-dependent hydroxyl radical pathways in the hypothalamus.
  • Chalepakis G et al: A model for hormone receptor binding to the mouse mammary tumour virus regulatory element based on hydroxyl radical footprinting.
  • Lai CJ et al: The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats.
  • Kao CH et al: Lipopolysaccharide- and glutamate-induced hypothalamic hydroxyl radical elevation and fever can be suppressed by N-methyl-D-aspartate-receptor antagonists.
  • Ching TL et al: Cimetidine and other H2 receptor antagonists as powerful hydroxyl radical scavengers.
  • Huang WT et al: An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.
  • Lin YS et al: Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs.
  • Anzai K et al: Effects of hydroxyl radical and sulfhydryl reagents on the open probability of the purified cardiac ryanodine receptor channel incorporated into planar lipid bilayers.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705432084.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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18. |||||||||. 98%  Cooper IF, Siadaty MS: 'Mammals' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Mammal;HydroxylRadical:705554305. ISSN: 2331-5717. 2014/12/27
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  • [Title] 'Mammals' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Mammal' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Mammal'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 21 publications, and group two 107858 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Mammals' associated with 'Hydroxyl Radical': Top Publications.
  • Ienaga K et al: Daily hydroxyl radical scavenging capacity of mammals.
  • Goyal MM et al: Hydroxyl radical generation theory: a possible explanation of unexplained actions of mammalian catalase.
  • Sandström BE: Effects of quin2 acetoxymethyl ester on H2O2-induced DNA single-strand breakage in mammalian cells: H2O2-concentration-dependent inhibition of damage and additive protective effect with the hydroxyl-radical scavenger dimethyl sulphoxide.
  • Pennathur S et al: A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease.
  • Deshmukh AB et al: Hydroxyl radical mediates the augmented angiotensin II responses in thoracic aorta of spontaneously hypertensive rats.
  • Lancelot E et al: Glutamate induces hydroxyl radical formation in vivo via activation of nitric oxide synthase in Sprague-Dawley rats.
  • Ewing D et al: Radiation protection of in vitro mammalian cells: effects of hydroxyl radical scavengers on the slopes and shoulders of survival curves.
  • Lin YS et al: Acute neurogenic airway plasma exudation and edema induced by inhaled wood smoke in guinea pigs: role of tachykinins and hydroxyl radical.
  • Hsu TH et al: Wood smoke-induced airway hyperreactivity in guinea pigs: time course, and role of leukotrienes and hydroxyl radical.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705554305.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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19. |||||||||. 97%  Cooper IF, Siadaty MS: 'Plants' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Plant;HydroxylRadical:705530315. ISSN: 2331-5717. 2014/1/5
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  • [Title] 'Plants' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Plant' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Plant'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 25 publications, and group two 39024 publications.
  • Here are the top 10.
  • Kwon do Y et al: Comparison of hydroxyl radical, peroxyl radical, and peroxynitrite scavenging capacity of extracts and active components from selected medicinal plants.
  • Valentão P et al: Antioxidant activity of Hypericum androsaemum infusion: scavenging activity against superoxide radical, hydroxyl radical and hypochlorous acid.
  • Valentão P et al: Studies on the antioxidant activity of Lippia citriodora infusion: scavenging effect on superoxide radical, hydroxyl radical and hypochlorous acid.
  • Akashi K et al: Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger.
  • Gao YT et al: [Effects of Panax notoginseng saponins on antioxidation and preventing DNA damage caused by hydroxyl radical].
  • Valentão P et al: Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid.
  • Cao Y et al: Determination of hydroxyl radical by capillary electrophoresis and studies on hydroxyl radical scavenging activities of Chinese herbs.
  • Thind TS et al: Studies on cytotoxic, hydroxyl radical scavenging and topoisomerase inhibitory activities of extracts of Tabernaemontana divaricata (L.) R.Br. ex Roem. and Schult.
  • Jang MH et al: Hydroxyl radical scavenging activities of isoquinoline alkaloids isolated from Coptis chinensis.
  • Wang X et al: Assessment of hydroxyl radical generation and radical scavenging activity of Chinese medicinal herbs using GC-MS.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705530315.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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20. |||||||||. 97%  Cooper IF, Siadaty MS: 'Humans' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Human;HydroxylRadical:707319915. ISSN: 2331-5717. 2014/11/8
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  • [Title] 'Humans' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Human' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Human'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 25 publications, and group two 21754 publications.
  • Here are the top 10.
  • Borthiry GR et al: Reduction of hexavalent chromium by human cytochrome b5: generation of hydroxyl radical and superoxide.
  • Ledo A et al: Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants.
  • Yu JW et al: Iron chlorin e6 scavenges hydroxyl radical and protects human endothelial cells against hydrogen peroxide toxicity.
  • Matsui S et al: Stimulatory effects of hydroxyl radical generation by Ga-Al-As laser irradiation on mineralization ability of human dental pulp cells.
  • Yu Y et al: Hydroxyl radicalOH) played a pivotal role in oridonin-induced apoptosis and autophagy in human epidermoid carcinoma A431 cells.
  • Pelle E et al: Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger.
  • Fickl H et al: Vanadium promotes hydroxyl radical formation by activated human neutrophils.
  • Chou DS et al: Baicalein induction of hydroxyl radical formation via 12-lipoxygenase in human platelets: an ESR study.
  • Li SP et al: Hydroxyl radical scavenging mechanism of human erythrocytes by quercetin-germanium (IV) complex.
  • Chen CY et al: Nickel-induced plasma lipid peroxidation and effect of antioxidants in human blood: involvement hydroxyl radical formation and depletion of alpha-tocopherol.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707319915.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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21. |||||||||. 97%  Cooper IF, Siadaty MS: 'Intellectual Products' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; IntellectualProduct;HydroxylRadical:707209200. ISSN: 2331-5717. 2014/12/6
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  • [Title] 'Intellectual Products' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Intellectual Product' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Intellectual Product'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 60 publications, and group two 41928 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Functional Concepts' associated with 'Hydroxyl Radical': Top Publications.
  • Minakata D et al: Reactivity of aqueous phase hydroxyl radical with halogenated carboxylate anions: experimental and theoretical studies.
  • Francés-Monerris A et al: Theoretical study of the hydroxyl radical addition to uracil and photochemistry of the formed U6OH• adduct.
  • Zhang Y et al: Theoretical study on the gas phase reaction of allyl chloride with hydroxyl radical.
  • Kiselar JG et al: Structural analysis of proinsulin hexamer assembly by hydroxyl radical footprinting and computational modeling.
  • Zhang Y et al: Theoretical study on the gas phase reaction of propargyl alcohol with hydroxyl radical.
  • Shannon RJ et al: A combined experimental and theoretical study of reactions between the hydroxyl radical and oxygenated hydrocarbons relevant to astrochemical environments.
  • Zhang Y et al: Theoretical study on the gas phase reaction of allyl alcohol with hydroxyl radical.
  • Long B et al: Theoretical study on the gas phase reaction of sulfuric acid with hydroxyl radical in the presence of water.
  • Sun J et al: Theoretical study on the gas phase reaction of acrylonitrile with a hydroxyl radical.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 707209200.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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22. |||||||||. 97%  Cooper IF, Siadaty MS: 'Antibiotics' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Antibiotic;HydroxylRadical:706938124. ISSN: 2331-5717. 2014/1/3
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  • [Title] 'Antibiotics' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Antibiotic' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Antibiotic'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 31 publications, and group two 11028 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Pharmacologic Substances or Antibiotics or Clinical Drugs' associated with 'Hydroxyl Radical': Top Publications.
  • Cons BM et al: High resolution hydroxyl radical footprinting of the binding of mithramycin and related antibiotics to DNA.
  • Choi H et al: Antimicrobial peptide pleurocidin synergizes with antibiotics through hydroxyl radical formation and membrane damage, and exerts antibiofilm activity.
  • Sampson TR et al: Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway.
  • Portugal J et al: Hydroxyl radical footprinting of the sequence-selective binding of netropsin and distamycin to DNA.
  • Doroshow JH: Anthracycline antibiotic-stimulated superoxide, hydrogen peroxide, and hydroxyl radical production by NADH dehydrogenase.
  • Dail MK et al: Hydroxyl-radical-induced degradative oxidation of beta-lactam antibiotics in water: absolute rate constant measurements.
  • Aoyagi K et al: Inhibition by heparin of protein kinase C activation and hydroxyl radical generation in puromycin aminonucleoside treated isolated rat hepatocytes.
  • Ohkuwa T et al: Hydroxyl radical formation in diabetic rats induced by streptozotocin.
  • Harris RN et al: Effect of doxorubicin-enhanced hydrogen peroxide and hydroxyl radical formation on calcium sequestration by cardiac sarcoplasmic reticulum.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706938124.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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23. |||||||||. 97%  Cooper IF, Siadaty MS: 'Carbohydrates' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Carbohydrate;HydroxylRadical:705644242. ISSN: 2331-5717. 2014/11/3
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  • [Title] 'Carbohydrates' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Carbohydrate' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Carbohydrate'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 31 publications, and group two 20195 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Carbohydrates' associated with 'Hydroxyl Radical': Top Publications.
  • Hawkins PT et al: Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate.
  • Ohashi Y et al: Detection of 2-deoxy-D-ribose radicals generated by the reaction with the hydroxyl radical using a rapid flow-ESR method.
  • Lai CJ et al: The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats.
  • Taga R et al: Hydroxyl radical participation in the in vitro effects of gram-negative endotoxin on cardiac sarcolemmal Na,K-ATPase activity.
  • Stadler K et al: Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes.
  • Obata T: Phytic acid suppresses 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in rat striatum.
  • Sato E et al: Clindamycin phosphate scavenges hydroxyl radical.
  • Liochev S et al: Vanadyl causes hydroxyl radical mediated degradation of deoxyribose.
  • Ohkuwa T et al: Hydroxyl radical formation in diabetic rats induced by streptozotocin.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705644242.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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24. |||||||||. 90%  Yamaguchi M: Hemibonding of hydroxyl radical and halide anion in aqueous solution. J Phys Chem A; 2011 Dec 29;115(51):14620-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemibonding of hydroxyl radical and halide anion in aqueous solution.
  • Molecular geometries and properties of the possible reaction products between the hydroxyl radical and the halide anions in aqueous solution were investigated.
  • The formation of two-center three-electron bonding (hemibonding) between the hydroxyl radical and halide anions (Cl, Br, I) was examined by density functional theory (DFT) calculation with a range-separated hybrid (RSH) exchange-correlation functional.
  • The long-range corrected hybrid functional (LC-ωPBE), which have given quantitatively satisfactory results for odd electron systems and excited states, was examined by test calculations for dihalogen radical anions (X(2)(-); X = Cl, Br, I) and hydroxyl radical-water clusters.
  • Equilibrium geometries with hemibonding between the hydroxyl radical and halide anions were located by including four hydrogen-bonded water molecules.
  • Calculated values of the free energy of reaction on the formation of hydroxyl halide radical anion from the hydroxyl radical and halide anion were endothermic for chloride but exothermic for bromide and iodide, which is consistent with experimental values of equilibrium constants.
  • [MeSH-major] Halogens / chemistry. Hydroxyl Radical / chemistry

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  • [Copyright] © 2011 American Chemical Society
  • (PMID = 22136588.001).
  • [ISSN] 1520-5215
  • [Journal-full-title] The journal of physical chemistry. A
  • [ISO-abbreviation] J Phys Chem A
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Halogens; 0 / Solutions; 059QF0KO0R / Water; 3352-57-6 / Hydroxyl Radical
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25. |||||||||. 89%  Li X: Solvent effects and improvements in the deoxyribose degradation assay for hydroxyl radical-scavenging. Food Chem; 2013 Dec 1;141(3):2083-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solvent effects and improvements in the deoxyribose degradation assay for hydroxyl radical-scavenging.
  • The deoxyribose degradation assay is widely used to evaluate the hydroxyl (OH) radical-scavenging ability of food or medicines.
  • We compared the hydroxyl radical-scavenging activity of 25 antioxidant samples prepared in ethanol solution with samples prepared after removing the ethanol (residue).
  • Most pure organic solvents (especially alcohols) could effectively scavenge hydroxyl radicals.
  • As hydroxyl radicals have extremely high reactivities, they will quickly react with surrounding solvent molecules.
  • The proposed method is regarded as a reliable hydroxyl radical-scavenging assay, suitable for all types of antioxidants.
  • [MeSH-major] Chemistry Techniques, Analytical / methods. Deoxyribose / chemistry. Free Radical Scavengers / chemistry. Hydroxyl Radical / chemistry

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  • [Copyright] Copyright © 2013 Elsevier Ltd. All rights reserved.
  • (PMID = 23870931.001).
  • [ISSN] 0308-8146
  • [Journal-full-title] Food chemistry
  • [ISO-abbreviation] Food Chem
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Free Radical Scavengers; 0 / Solvents; 3352-57-6 / Hydroxyl Radical; 533-67-5 / Deoxyribose
  • [Keywords] NOTNLM ; ()OH / Antioxidant / BHA / DMF / DMSO / Deoxyribose degradation assay / FC / FDA / Food and Drug Administration of USA / GSH / Hydroxyl radical scavenging / Improvement / MEAS / MEGB / N,N-dimethylformamide / ROS / RSD / SD / Solvent effect / THF / butylated hydroxyanisole / dimethyl sulfoxide / final concentration / glutathione / methanol extract from Gynura bicolor Roxb. DC / methanol extract of Aquilaria sinensis leaves / reactive oxygen species / relative standard deviation / standard deviation / tetrahydrofuran
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26. |||||||||. 88%  Ray PZ, Tarr MA: Petroleum films exposed to sunlight produce hydroxyl radical. Chemosphere; 2014 May;103:220-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Petroleum films exposed to sunlight produce hydroxyl radical.
  • Sunlight exposed oil films on seawater or pure water produced substantial amounts of hydroxyl radical as a result of irradiation.
  • Photochemical production of hydroxyl radical was measured with benzoic acid as a selective chemical probe in the aqueous layer.
  • Total hydroxyl radical formation was studied using high benzoic acid concentrations and varying exposure time.
  • The total amount of hydroxyl radical produced in 24 h irradiations of thin oil films over Gulf of Mexico water and pure water were 3.7×10(-7) and 4.2×10(-7) moles respectively.
  • Steady state concentrations of hydroxyl radical were measured using a competition kinetics approach.
  • Hydroxyl radical concentrations of 1.2×10(-16) to 2.4×10(-16) M were observed for seawater and pure water under oil films.
  • The addition of TiO2 nanoparticles dramatically changed the observed formation rate of hydroxyl radical in the systems with NP water at pH 3, showing increased formation rate in many cases.
  • With photocatalyst, the steady state concentration of radical decreased, predominantly due to an increase in the hydroxyl radical scavenging rate with oxide present.
  • This study illustrates that oil is a strong and important source of hydroxyl radical when exposed to sunlight.
  • The fate of oil and other dissolved species following oil spills will be heavily dependent on the formation and fate of hydroxyl radical.
  • [MeSH-major] Hydroxyl Radical / chemical synthesis. Petroleum / radiation effects. Petroleum Pollution. Photochemical Processes. Seawater / chemistry. Sunlight. Water Pollutants, Chemical / chemistry

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  • [Copyright] Copyright © 2013 Elsevier Ltd. All rights reserved.
  • (PMID = 24405967.001).
  • [ISSN] 1879-1298
  • [Journal-full-title] Chemosphere
  • [ISO-abbreviation] Chemosphere
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Petroleum; 0 / Water Pollutants, Chemical; 15FIX9V2JP / titanium dioxide; 3352-57-6 / Hydroxyl Radical; D1JT611TNE / Titanium
  • [Keywords] NOTNLM ; Crude oil / Hydroxyl radical / Oil spill / Petroleum / Photochemistry / Reactive transient
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27. |||||||||. 87%  Mitroka S, Zimmeck S, Troya D, Tanko JM: How solvent modulates hydroxyl radical reactivity in hydrogen atom abstractions. J Am Chem Soc; 2010 Mar 10;132(9):2907-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] How solvent modulates hydroxyl radical reactivity in hydrogen atom abstractions.
  • The hydroxyl radical (HO*) is a highly reactive oxygen-centered radical whose bimolecular rate constants for reaction with organic compounds (hydrogen atom abstraction) approach the diffusion-controlled limit in aqueous solution.
  • The results reported herein show that hydroxyl radical is considerably less reactive in dipolar, aprotic solvents such as acetonitrile.
  • This diminished reactivity is explained on the basis of a polarized transition state for hydrogen abstraction, in which the oxygen of the hydroxyl radical becomes highly negative and can serve as a hydrogen bond acceptor.
  • This hypothesis explains hydroxyl radical reactivity both in solution and in the gas phase and may be the basis for a "containment strategy" used by Nature when hydroxyl radical is produced endogenously.
  • [MeSH-major] Acetonitriles / chemistry. Hydrogen / chemistry. Hydroxyl Radical / chemistry. Organic Chemicals / chemistry. Water / chemistry

  • HSDB. structure - HYDROGEN.
  • HSDB. structure - ACETONITRILE.
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  • (PMID = 20146469.001).
  • [ISSN] 1520-5126
  • [Journal-full-title] Journal of the American Chemical Society
  • [ISO-abbreviation] J. Am. Chem. Soc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acetonitriles; 0 / Organic Chemicals; 0 / Solvents; 059QF0KO0R / Water; 3352-57-6 / Hydroxyl Radical; 7YNJ3PO35Z / Hydrogen; Z072SB282N / acetonitrile
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28. |||||||||. 86%  Vandjelovic N, Zhu H, Misra HP, Zimmerman RP, Jia Z, Li Y: EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin. Mol Cell Biochem; 2012 May;364(1-2):71-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin.
  • The root mechanism of damage likely involves the inflammatory cascade, specifically compounds known as reactive oxygen species such as the hydroxyl radical.
  • However, direct evidence for the hydroxyl-scavenging capacity of pravastatin and fluvastatin, two forms of statins being widely used to lower LDL cholesterol, is still lacking in literature.
  • In this study, electron paramagnetic resonance spectroscopy in combination with 5,5-dimethyl-1-pyrroline N-oxide (DMPO)-spin-trapping technique was utilized to determine the abilities of pravastatin and fluvastatin in scavenging hydroxyl radical generated from Fe(II) with H(2)O(2) system.
  • We have demonstrated here for the first time that pravastatin and fluvastatin at physiologically relevant concentrations significantly decreased formation of DMPO-OH adduct indicating that both compounds could directly scavenge hydroxyl radicals.
  • The hydroxyl radical sequestering ability of pravastatin and fluvastatin reported in this study may contribute to their beneficial use in certain types of cancer and in cardiovascular disease.
  • [MeSH-major] DNA Breaks / drug effects. Fatty Acids, Monounsaturated / pharmacology. Hydroxyl Radical / metabolism. Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology. Indoles / pharmacology. Pravastatin / pharmacology
  • [MeSH-minor] Electron Spin Resonance Spectroscopy / methods. Ferrous Compounds / pharmacology. Free Radical Scavengers / pharmacology. Humans. Hydrogen Peroxide / pharmacology. Plasmids / drug effects. Plasmids / genetics. Reactive Oxygen Species / chemistry. Reactive Oxygen Species / metabolism. Spin Trapping / methods

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  • (PMID = 22207075.001).
  • [ISSN] 1573-4919
  • [Journal-full-title] Molecular and cellular biochemistry
  • [ISO-abbreviation] Mol. Cell. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Fatty Acids, Monounsaturated; 0 / Ferrous Compounds; 0 / Free Radical Scavengers; 0 / Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0 / Indoles; 0 / Reactive Oxygen Species; 3352-57-6 / Hydroxyl Radical; 4L066368AS / fluvastatin; BBX060AN9V / Hydrogen Peroxide; KXO2KT9N0G / Pravastatin
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29. |||||||||. 86%  Wu L, Yang Y, Zhang H, Zhu G, Zhang X, Chen J: Sensitive electrochemical detection of hydroxyl radical with biobarcode amplification. Anal Chim Acta; 2012 Dec 5;756:1-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sensitive electrochemical detection of hydroxyl radical with biobarcode amplification.
  • By using biobarcode nanoparticles, we have successfully constructed a DNA-based biosensor for amplified electrochemical detection of hydroxyl radicalOH).
  • ·OH generated from Fenton reaction could induce serious oxidative damage of the DNA layer adsorbed on the electrode surface, which was monitored by an intercalating probe, methylene blue (MB).
  • The developed DNA-based biosensor could detect ·OH quantitatively with wide linear range up to 10mM and low detection limit of 3 μM, and exhibited satisfactory selectivity.
  • On the other hand, this electrochemical biosensor could have potential application in the evaluation of antioxidant capacity.
  • [MeSH-major] Biosensing Techniques / instrumentation. Electrochemical Techniques. Hydroxyl Radical / analysis. Metal Nanoparticles / chemistry

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  • [Copyright] Copyright © 2012 Elsevier B.V. All rights reserved.
  • (PMID = 23176733.001).
  • [ISSN] 1873-4324
  • [Journal-full-title] Analytica chimica acta
  • [ISO-abbreviation] Anal. Chim. Acta
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 3352-57-6 / Hydroxyl Radical
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30. |||||||||. 86%  Page SE, Arnold WA, McNeill K: Assessing the contribution of free hydroxyl radical in organic matter-sensitized photohydroxylation reactions. Environ Sci Technol; 2011 Apr 1;45(7):2818-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessing the contribution of free hydroxyl radical in organic matter-sensitized photohydroxylation reactions.
  • Photochemical formation of reactive oxygen species from dissolved organic matter (DOM) is incompletely understood, especially in the case of hydroxyl radical (•OH) production.
  • Many studies have used various probes to detect photochemically produced •OH from DOM, but the fundamental reactions of these probes are not necessarily specific for free •OH and may also detect lower-energy hydroxylation agents.
  • In this study, two tests were applied that have previously been used as a diagnostic for the presence of free •OH: methane quenching of •OH and hydroxybenzoic acid (hBZA) product yields.
  • Overall, the results provide compelling evidence that all isolates studied photochemically produce free •OH.
  • The hydroxylating acitivity of Elliot Soil Humic Acid and Pony Lake Fulvic Acid, however, also had a significant contribution from a photochemically generated hydroxylating agent that is lower in energy than free •OH.
  • Catalase quenching experiments were conducted to assess whether hydrogen peroxide was the immediate precursor to hydroxyl in these systems.
  • [MeSH-major] Hydroxyl Radical / chemistry. Organic Chemicals / chemistry. Reactive Oxygen Species / chemistry

  • HSDB. structure - TEREPHTHALIC ACID.
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  • (PMID = 21375262.001).
  • [ISSN] 1520-5851
  • [Journal-full-title] Environmental science & technology
  • [ISO-abbreviation] Environ. Sci. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzoates; 0 / Organic Chemicals; 0 / Phthalic Acids; 0 / Reactive Oxygen Species; 3352-57-6 / Hydroxyl Radical; 6S7NKZ40BQ / terephthalic acid
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31. |||||||||. 85%  Spasojević I, Mojović M, Blagojević D, Spasić SD, Jones DR, Nikolić-Kokić A, Spasić MB: Relevance of the capacity of phosphorylated fructose to scavenge the hydroxyl radical. Carbohydr Res; 2009 Jan 5;344(1):80-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relevance of the capacity of phosphorylated fructose to scavenge the hydroxyl radical.
  • The hydroxyl radical (*OH) has detrimental biological activity due to its very high reactivity.
  • Our experiments were designed to determine the effects of equimolar concentrations of glucose, fructose and mannitol and three phosphorylated forms of fructose (fructose-1-phosphate (F1P); fructose-6-phosphate (F6P); and fructose-1,6-bis(phosphate) (F16BP)) on *OH radical production via the Fenton reaction.
  • EPR spectroscopy using spin-trap DEPMPO was applied to detect radical production.
  • We found that the percentage inhibition of *OH radical formation decreased in the order F16BP>F1P>F6P>fructose>mannitol=glucose.
  • As ketoses can sequester redox-active iron thus preventing the Fenton reaction, the Haber-Weiss-like system was also employed to generate *OH, so that the effect of iron sequestration could be distinguished from direct *OH radical scavenging.
  • In the latter system, the rank order of *OH scavenging activity was F16BP>F1P>F6P>fructose=mannitol=glucose.
  • [MeSH-major] Fructose / chemistry. Hydroxyl Radical / chemistry

  • HSDB. structure - GLUCOSE.
  • HSDB. structure - D-MANNITOL.
  • HSDB. structure - IRON.
  • HSDB. structure - FRUCTOSE.
  • HSDB. structure - HYDROGEN PEROXIDE.
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  • (PMID = 18947823.001).
  • [ISSN] 1873-426X
  • [Journal-full-title] Carbohydrate research
  • [ISO-abbreviation] Carbohydr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Fenton's reagent; 0 / Fructosephosphates; 15978-08-2 / fructose-1-phosphate; 30237-26-4 / Fructose; 3352-57-6 / Hydroxyl Radical; 3OWL53L36A / Mannitol; 6814-87-5 / fructose-6-phosphate; BBX060AN9V / Hydrogen Peroxide; E1UOL152H7 / Iron; EC 3.1.3.11 / Fructose-Bisphosphatase; IY9XDZ35W2 / Glucose
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32. ||||||||.. 85%  Zigah D, Rodríguez-López J, Bard AJ: Quantification of photoelectrogenerated hydroxyl radical on TiO2 by surface interrogation scanning electrochemical microscopy. Phys Chem Chem Phys; 2012 Oct 5;14(37):12764-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quantification of photoelectrogenerated hydroxyl radical on TiO2 by surface interrogation scanning electrochemical microscopy.
  • The surface interrogation mode of scanning electrochemical microscopy (SI-SECM) was used for the detection and quantification of adsorbed hydroxyl radical ˙OH((ads)) generated photoelectrochemically at the surface of a nanostructured TiO(2) substrate electrode.
  • A typical ˙OH((ads)) saturation coverage of 338 μC cm(-2) was found in our nanostructured samples by its reduction with the electrogenerated IrCl(6)(3-).
  • The decay kinetics of ˙OH((ads)) by dimerization to produce H(2)O(2) were studied through the time dependence of the SI-SECM signal and the surface dimerization rate constant was found to be ~k(OH) = 2.2 × 10(3) mol(-1) m(2) s(-1).
  • A radical scavenger, such as methanol, competitively consumes ˙OH((ads)) and yields a shorter SI-SECM transient, where a pseudo-first order rate analysis at 2 M methanol yields a decay constant of k'(MeOH) ~ 1 s(-1).
  • [MeSH-major] Hydroxyl Radical / analysis. Titanium / chemistry

  • HSDB. structure - TITANIUM DIOXIDE.
  • HSDB. structure - IRIDIUM, ELEMENTAL.
  • HSDB. structure - TITANIUM.
  • HSDB. structure - HYDROGEN PEROXIDE.
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  • (PMID = 22903377.001).
  • [ISSN] 1463-9084
  • [Journal-full-title] Physical chemistry chemical physics : PCCP
  • [ISO-abbreviation] Phys Chem Chem Phys
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chlorides; 0 / iridium chloride; 15FIX9V2JP / titanium dioxide; 3352-57-6 / Hydroxyl Radical; 44448S9773 / Iridium; BBX060AN9V / Hydrogen Peroxide; D1JT611TNE / Titanium
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33. ||||||||.. 84%  Carr S, Heard DE, Blitz MA: Comment on "Atmospheric hydroxyl radical production from electronically excited NO2 and H2O". Science; 2009 Apr 17;324(5925):336; author reply 336
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comment on "Atmospheric hydroxyl radical production from electronically excited NO2 and H2O".
  • Li et al. (Reports, 21 March 2008, p. 1657) suggested that the reaction between electronically excited nitrogen dioxide and water vapor is an important atmospheric source of the hydroxyl radical.
  • However, under conditions that better approximate the solar flux, we find no evidence for OH production from this reaction.

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  • [CommentOn] Science. 2008 Mar 21;319(5870):1657-60 [18356524.001]
  • (PMID = 19372414.001).
  • [ISSN] 1095-9203
  • [Journal-full-title] Science (New York, N.Y.)
  • [ISO-abbreviation] Science
  • [Language] eng
  • [Publication-type] Comment; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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34. ||||||||.. 84%  Dong MM, Rosario-Ortiz FL: Photochemical formation of hydroxyl radical from effluent organic matter. Environ Sci Technol; 2012 Apr 3;46(7):3788-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Photochemical formation of hydroxyl radical from effluent organic matter.
  • The photochemical formation of hydroxyl radical (HO•) from effluent organic matter (EfOM) was evaluated using three bulk wastewater samples collected at different treatment facilities under simulated sunlight.
  • [MeSH-major] Hydroxyl Radical / chemistry. Organic Chemicals / chemistry. Photochemical Processes. Waste Disposal, Fluid

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 22352464.001).
  • [ISSN] 1520-5851
  • [Journal-full-title] Environmental science & technology
  • [ISO-abbreviation] Environ. Sci. Technol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Nitrates; 0 / Organic Chemicals; 0 / Phenols; 3352-57-6 / Hydroxyl Radical
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35. ||||||||.. 84%  Aust SD, Terry S, Hebdon T, Gunderson B, Terry M, Dimalanta R: Determining the local origin of hydroxyl radical generation during phacoemulsification. J Cataract Refract Surg; 2011 Jun;37(6):1154-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Determining the local origin of hydroxyl radical generation during phacoemulsification.
  • PURPOSE: To determine the local origin of hydroxyl radicals during phacoemulsification using an ultrasonic phacoemulsification device that includes longitudinal and torsional modalities.
  • Hydroxyl radical concentrations during longitudinal and torsional phacoemulsification were quantitated as malondialdehyde (MDA) determined spectrophotometrically using the deoxyribose assay.
  • CONCLUSION: Although a significantly greater proportion of the hydroxyl radicals generated during ultrasound modality were formed outside the phaco tip (91.1% torsional; 71.6% longitudinal), torsional ultrasound generated only about one-fourth the amount of MDA as longitudinal ultrasound in total and about one-third that generated outside the tip (7.02 nM versus 21.1 nM).
  • [MeSH-major] Acetates / chemistry. Hydroxyl Radical / analysis. Minerals / chemistry. Phacoemulsification. Sodium Chloride / chemistry

  • MedlinePlus Health Information. consumer health - Minerals.
  • HSDB. structure - MALONALDEHYDE.
  • HSDB. structure - SODIUM CHLORIDE.
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  • [Copyright] Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
  • (PMID = 21596259.001).
  • [ISSN] 1873-4502
  • [Journal-full-title] Journal of cataract and refractive surgery
  • [ISO-abbreviation] J Cataract Refract Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acetates; 0 / BSS solution; 0 / Drug Combinations; 0 / Minerals; 3352-57-6 / Hydroxyl Radical; 4Y8F71G49Q / Malondialdehyde; 7647-14-5 / Sodium Chloride
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36. ||||||||.. 83%  Lü JM, Weakley SM, Yang Z, Hu M, Yao Q, Chen C: Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid. Curr Pharm Des; 2012;18(38):6339-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid.
  • We found that Rb1 can significantly and selectively reduce hydroxyl radical (●OH) and hypochlorous acid (HOCl), two of the strongest ROS, with unique molecular mechanisms in a cell-free system.
  • Rb1 directly scavenges the ●OH and protects plasmid DNA from damage induced by ●OH.
  • OH likely attacks the double bond on the side chain of Rb1 as well as hydrogen atoms adjacent to the -OH groups, including those of sugar moieties.
  • HOCl is added to the double bond of Rb1; the -Cl group and -OH group of HOCl possibly bond at C-24 and C-25 of Rb1 based on the regioselectivity of Markovnikov's Rule.
  • [MeSH-major] DNA Damage. Free Radical Scavengers / pharmacology. Ginsenosides / pharmacology. Hydroxyl Radical / metabolism. Hypochlorous Acid / metabolism. Oxidative Stress / drug effects

  • HSDB. structure - L-TYROSINE.
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  • (PMID = 22974003.001).
  • [ISSN] 1873-4286
  • [Journal-full-title] Current pharmaceutical design
  • [ISO-abbreviation] Curr. Pharm. Des.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL072716; United States / NHLBI NIH HHS / HL / HL083471; United States / NHLBI NIH HHS / HL / T32HL083774
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Free Radical Scavengers; 0 / Ginsenosides; 0 / ginsenoside Rb1; 3352-57-6 / Hydroxyl Radical; 42HK56048U / Tyrosine; 712K4CDC10 / Hypochlorous Acid
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37. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Cell or Molecular Dysfunctions' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; CellOrMolecular;HydroxylRadical:706270814. ISSN: 2331-5717. 2014/12/25
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  • [Title] 'Cell or Molecular Dysfunctions' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Cell or Molecular Dysfunction' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Cell or Molecular Dysfunction'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 23 publications, and group two 18347 publications.
  • Here are the top 10.
  • Ren JG et al: Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation.
  • Shao L et al: Fragmentation and rapid shortening of telomere in HeLa cells in the early phase of hydroxyl radical-induced apoptosis.
  • Chen W et al: Myricetin affords protection against peroxynitrite-mediated DNA damage and hydroxyl radical formation.
  • Chen W et al: Ethyl pyruvate inhibits peroxynitrite-induced DNA damage and hydroxyl radical generation: implications for neuroprotection.
  • Chen W et al: Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.
  • Jeong JB et al: Effect of extracts from pine needle against oxidative DNA damage and apoptosis induced by hydroxyl radical via antioxidant activity.
  • Shi T et al: Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations.
  • Chen CL et al: Hydroxyl radical formation and oxidative DNA damage induced by areca quid in vivo.
  • Gao YT et al: [Effects of Panax notoginseng saponins on antioxidation and preventing DNA damage caused by hydroxyl radical].
  • Burkitt MJ et al: Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706270814.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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38. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Steroids' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Steroid;HydroxylRadical:705862566. ISSN: 2331-5717. 2014/2/25
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  • [Title] 'Steroids' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Steroid' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Steroid'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 25 publications, and group two 17317 publications.
  • Here are the top 10.
  • Kobayashi Y et al: Passive ultrasonic irrigation in the presence of a low concentration of hydrogen peroxide enhances hydroxyl radical generation and bactericidal effect against Enterococcus faecalis.
  • Górska AM et al: The effect of caffeine on MDMA-induced hydroxyl radical production in the mouse striatum.
  • Shannon RJ et al: Accelerated chemistry in the reaction between the hydroxyl radical and methanol at interstellar temperatures facilitated by tunnelling.
  • Passananti M et al: The impact of the hydroxyl radical photochemical sources on the rivastigmine drug transformation in mimic and natural waters.
  • Kim MK et al: Effects of natural water constituents on the photo-decomposition of methylmercury and the role of hydroxyl radical.
  • Drouin BJ: Isotopic spectra of the hydroxyl radical.
  • Seal P et al: Kinetics of the hydrogen atom abstraction reactions from 1-butanol by hydroxyl radical: theory matches experiment and more.
  • Kaur G et al: Exploring water catalysis in the reaction of thioformic Acid with hydroxyl radical: a global reaction route mapping perspective.
  • Vu ND et al: Absolute rate coefficient of the gas-phase reaction between hydroxyl radical (OH) and hydroxyacetone: investigating the effects of temperature and pressure.
  • Macrea M et al: Leptin's activity on the hydroxyl radical: a possible link to the oxidative stress-related endothelial vasodilation in patients with obstructive sleep apnea.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705862566.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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39. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Functional Concepts' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; FunctionalConcept;HydroxylRadical:706272667. ISSN: 2331-5717. 2014/4/25
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  • [Title] 'Functional Concepts' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Functional Concept' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Functional Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 28 publications, and group two 17938 publications.
  • Here are the top 10.
  • Ranpura H et al: Finding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMR.
  • Madugundu GS et al: Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA.
  • Ueno M et al: Method for assessing X-ray-induced hydroxyl radical-scavenging activity of biological compounds/materials.
  • Vu ND et al: Absolute rate coefficient of the gas-phase reaction between hydroxyl radical (OH) and hydroxyacetone: investigating the effects of temperature and pressure.
  • Page SE et al: Evidence for dissolved organic matter as the primary source and sink of photochemically produced hydroxyl radical in arctic surface waters.
  • Górska AM et al: The effect of caffeine on MDMA-induced hydroxyl radical production in the mouse striatum.
  • Francés-Monerris A et al: Theoretical study of the hydroxyl radical addition to uracil and photochemistry of the formed U6OH• adduct.
  • Xiao R et al: Using pulsed wave ultrasound to evaluate the suitability of hydroxyl radical scavengers in sonochemical systems.
  • Milne L et al: Comparison of hydroxyl radical formation in aqueous solutions at different ultrasound frequencies and powers using the salicylic acid dosimeter.
  • Jørgensen S et al: The gas-phase reaction of methane sulfonic acid with the hydroxyl radical without and with water vapor.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706272667.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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40. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Medical Devices' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; MedicalDevice;HydroxylRadical:705560440. ISSN: 2331-5717. 2014/2/25
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  • [Title] 'Medical Devices' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Medical Device' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Medical Device'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 24 publications, and group two 78427 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Medical Devices' associated with 'Hydroxyl Radical': Top Publications.
  • Price M et al: Monitoring singlet oxygen and hydroxyl radical formation with fluorescent probes during photodynamic therapy.
  • Leeuwenburgh C et al: Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats.
  • Hryniewicz MM et al: Hydroxyl radical footprints and half-site arrangements of binding sites for the CysB transcriptional activator of Salmonella typhimurium.
  • Bialonska D et al: Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology.
  • Leeuwenburgh C et al: Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
  • Chakinala AG et al: Intensification of hydroxyl radical production in sonochemical reactors.
  • Fortier CA et al: Covalently bound fluorescent probes as reporters for hydroxyl radical penetration into liposomal membranes.
  • Anderson TN et al: Diode-laser-based ultraviolet-absorption sensor for high-speed detection of the hydroxyl radical.
  • Milne L et al: Comparison of hydroxyl radical formation in aqueous solutions at different ultrasound frequencies and powers using the salicylic acid dosimeter.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705560440.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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41. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Laboratory Procedures' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; LaboratoryProcedure;HydroxylRadical:705279723. ISSN: 2331-5717. 2014/4/27
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  • [Title] 'Laboratory Procedures' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'laboratory procedure' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'laboratory procedure'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 64 publications, and group two 61646 publications.
  • Here are the top 10.
  • Nobushi Y et al: Selective detection of hydroxyl radical scavenging capacity based on electrogenerated chemiluminescence detection using tris(2,2'-bipyridine)ruthenium(III) by flow injection analysis.
  • Kiselar JG et al: Future directions of structural mass spectrometry using hydroxyl radical footprinting.
  • Lancaster L et al: The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography.
  • Wang L et al: Structural mass spectrometry of proteins using hydroxyl radical based protein footprinting.
  • Vasquez-Vivar J et al: Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation.
  • Yoshioka H et al: Spin-trapping study on the hydroxyl radical formed from a tea catechin-Cu(II) system.
  • Zigah D et al: Quantification of photoelectrogenerated hydroxyl radical on TiO2 by surface interrogation scanning electrochemical microscopy.
  • Domingues P et al: Detection and characterization of hydroxyl radical adducts by mass spectrometry.
  • Wang X et al: Assessment of hydroxyl radical generation and radical scavenging activity of Chinese medicinal herbs using GC-MS.
  • Maciel E et al: Liquid chromatography/tandem mass spectrometry analysis of long-chain oxidation products of cardiolipin induced by the hydroxyl radical.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705279723.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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42. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Hazardous Or Poisonous Substances' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; HazardousOrPoisonous;HydroxylRadical:705716824. ISSN: 2331-5717. 2014/4/26
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  • [Title] 'Hazardous Or Poisonous Substances' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'hazardous or poisonous substance' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'hazardous or poisonous substance'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 67 publications, and group two 43483 publications.
  • Here are the top 10.
  • Carr S et al: Comment on "Atmospheric hydroxyl radical production from electronically excited NO2 and H2O".
  • Borthiry GR et al: Reduction of hexavalent chromium by human cytochrome b5: generation of hydroxyl radical and superoxide.
  • Mollner AK et al: Rate of gas phase association of hydroxyl radical and nitrogen dioxide.
  • Li S et al: Atmospheric hydroxyl radical production from electronically excited NO2 and H2O.
  • Noda Y et al: Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine.
  • Lai CJ et al: The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats.
  • Wang S et al: The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation.
  • Obata T et al: Protective effect of diltiazem, a L-type calcium channel antagonist, on bisphenol A-enhanced hydroxyl radical generation by 1-methyl-4-phenylpyridinium ion in rat striatum.
  • Luo Y et al: EPR detection of hydroxyl radical generation and its interaction with antioxidant system in Carassius auratus exposed to pentachlorophenol.
  • Thomas B et al: In vivo hydroxyl radical generation in the striatum following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705716824.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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43. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Inorganic Chemicals' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; InorganicChemical;HydroxylRadical:705553015. ISSN: 2331-5717. 2014/4/24
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  • [Title] 'Inorganic Chemicals' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'inorganic chemical' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'inorganic chemical'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 109 publications, and group two 13730 publications.
  • Here are the top 10.
  • San Pedro JM et al: Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine.
  • Ding F et al: Three-dimensional RNA structure refinement by hydroxyl radical probing.
  • Gómez Alvarez E et al: Unexpectedly high indoor hydroxyl radical concentrations associated with nitrous acid.
  • Watson C et al: Conformational analysis of therapeutic proteins by hydroxyl radical protein footprinting.
  • Li M et al: Lethal hydroxyl radical accumulation by a lactococcal bacteriocin, lacticin Q.
  • Meng FG et al: Redox regulation of protein tyrosine phosphatase activity by hydroxyl radical.
  • Goyal MM et al: Hydroxyl radical generation theory: a possible explanation of unexplained actions of mammalian catalase.
  • Jørgensen S et al: The gas-phase reaction of methane sulfonic acid with the hydroxyl radical without and with water vapor.
  • Adegoke O et al: A comparative study on the sensitive detection of hydroxyl radical using thiol-capped CdTe and CdTe/ZnS quantum dots.
  • Dong MM et al: Photochemical formation of hydroxyl radical from effluent organic matter.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705553015.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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44. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Nucleic Acids, Nucleosides, or Nucleotides' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; NucleicAcidNucleoside;HydroxylRadical:705550448. ISSN: 2331-5717. 2014/4/24
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  • [Title] 'Nucleic Acids, Nucleosides, or Nucleotides' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'nucleic acid nucleoside or nucleotide' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'nucleic acid nucleoside or nucleotide'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 48 publications, and group two 32624 publications.
  • Here are the top 10.
  • Lancaster L et al: The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography.
  • Fu H et al: Fast repair activities towards dGMP hydroxyl radical adducts by silybin and its analogues.
  • San Pedro JM et al: Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine.
  • Cohn CA et al: Pyrite-induced hydroxyl radical formation and its effect on nucleic acids.
  • Tsunoda M et al: Insights into the structures of DNA damaged by hydroxyl radical: crystal structures of DNA duplexes containing 5-formyluracil.
  • Gołembiowska K et al: Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum.
  • Bishop EP et al: A map of minor groove shape and electrostatic potential from hydroxyl radical cleavage patterns of DNA.
  • Barciszewska MZ et al: Structural changes of tRNA and 5S rRNA induced with magnesium and visualized with synchrotron mediated hydroxyl radical cleavage.
  • Huang CY et al: Fast repair of the poly G hydroxyl radical adduct by two phenylpropanoid glycosides.
  • Brenowitz M et al: Probing the structural dynamics of nucleic acids by quantitative time-resolved and equilibrium hydroxyl radical "footprinting".

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705550448.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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45. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Cell Components' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; CellComponent;HydroxylRadical:705548086. ISSN: 2331-5717. 2014/4/24
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  • [Title] 'Cell Components' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'cell component' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'cell component'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 45 publications, and group two 28549 publications.
  • Here are the top 10.
  • Lomakin IB et al: Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing.
  • Yu Y et al: Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.
  • Lai CJ et al: The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats.
  • Gómez-Toribio V et al: Induction of extracellular hydroxyl radical production by white-rot fungi through quinone redox cycling.
  • Unbehaun A et al: Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing.
  • Lancaster L et al: The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography.
  • Cohn CA et al: Pyrite-induced hydroxyl radical formation and its effect on nucleic acids.
  • Thomas C et al: Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation.
  • Heyno E et al: Oxygen activation at the plasma membrane: relation between superoxide and hydroxyl radical production by isolated membranes.
  • Song YG et al: Damage to the oxygen-evolving complex by superoxide anion, hydrogen peroxide, and hydroxyl radical in photoinhibition of photosystem II.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705548086.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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46. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Immunologic Factors' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; ImmunologicFactor;HydroxylRadical:705384838. ISSN: 2331-5717. 2014/1/25
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  • [Title] 'Immunologic Factors' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Immunologic Factor' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Immunologic Factor'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 23 publications, and group two 107711 publications.
  • Here are the top 10.
  • Fligiel SE et al: Evidence for a role of hydroxyl radical in immune-complex-induced vasculitis.
  • Ward PA et al: Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.
  • Schlatterer JC et al: Complementing global measures of RNA folding with local reports of backbone solvent accessibility by time resolved hydroxyl radical footprinting.
  • Hüttenhofer A et al: Hydroxyl radical cleavage of tRNA in the ribosomal P site.
  • Deperalta G et al: Structural analysis of a therapeutic monoclonal antibody dimer by hydroxyl radical footprinting.
  • Arvieux J et al: Oxidation of beta2-glycoprotein I (beta2GPI) by the hydroxyl radical alters phospholipid binding and modulates recognition by anti-beta2GPI autoantibodies.
  • Turnage RH et al: Complement activation by the hydroxyl radical during intestinal reperfusion.
  • Oldham KT et al: Activation of complement by hydroxyl radical in thermal injury.
  • Gurgul-Convey E et al: Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.
  • Khan SA et al: Hydroxyl radical mediates oxidative modification of caprine alpha-2 macroglobulin.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705384838.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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47. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Enzymes' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; Enzyme;HydroxylRadical:705371918. ISSN: 2331-5717. 2014/4/25
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  • [Title] 'Enzymes' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'enzyme' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'enzyme'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 42 publications, and group two 28089 publications.
  • Here are the top 10.
  • Chen J et al: Excess no predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical.
  • Meng FG et al: Redox regulation of protein tyrosine phosphatase activity by hydroxyl radical.
  • Tsai TL et al: Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
  • Vasquez-Vivar J et al: Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation.
  • Tatsumi H et al: Sensitive electrochemical detection of the hydroxyl radical using enzyme-catalyzed redox cycling.
  • Ochi A et al: Hydroxyl radical probing of tRNA (Gm18) methyltransferase [TrmH]-AdoMet-artificial tRNA ternary complex.
  • Ilangovan G et al: Heat shock-induced attenuation of hydroxyl radical generation and mitochondrial aconitase activity in cardiac H9c2 cells.
  • Guillén F et al: Production of hydroxyl radical by the synergistic action of fungal laccase and aryl alcohol oxidase.
  • Aoyagi K et al: Inhibition by heparin of protein kinase C activation and hydroxyl radical generation in puromycin aminonucleoside treated isolated rat hepatocytes.
  • Aoyagi K et al: The role of protein kinase C in the increased generation in isolated rat hepatocytes of the hydroxyl radical by puromycin aminonucleoside.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705371918.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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48. ||||||||.. 82%  Cooper IF, Siadaty MS: 'Clinical Attributes' associated with 'Hydroxyl Radical': Top Publications. BioMedLib Review; ClinicalAttribute;HydroxylRadical:706298817. ISSN: 2331-5717. 2014/1/25
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  • [Title] 'Clinical Attributes' associated with 'Hydroxyl Radical': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Clinical Attribute' for 'hydroxyl radical'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Clinical Attribute'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 22 publications, and group two 88589 publications.
  • Here are the top 10.
  • McCormick ML et al: Endogenous superoxide dismutase levels regulate iron-dependent hydroxyl radical formation in Escherichia coli exposed to hydrogen peroxide.
  • Az-ma T et al: Cytosolic Ca2+ movements of endothelial cells exposed to reactive oxygen intermediates: role of hydroxyl radical-mediated redox alteration of cell-membrane Ca2+ channels.
  • Zeitz O et al: Hydroxyl radical-induced acute diastolic dysfunction is due to calcium overload via reverse-mode Na(+)-Ca(2+) exchange.
  • Ray PZ et al: Petroleum films exposed to sunlight produce hydroxyl radical.
  • Luo Y et al: EPR detection of hydroxyl radical generation and its interaction with antioxidant system in Carassius auratus exposed to pentachlorophenol.
  • Prasad K et al: Influence of hydroxyl radical on rabbit airway smooth muscle chronically exposed to H2O2 in vivo.
  • Xie X et al: Hydroxyl radical generation and oxidative stress in earthworms (Eisenia fetida) exposed to decabromodiphenyl ether (BDE-209).
  • Brandi G et al: Cytocidal and filamentous response of Escherichia coli cells exposed to low concentrations of hydrogen peroxide and hydroxyl radical scavengers.
  • Sun Y et al: Hydroxyl radical generation and oxidative stress in Carassius auratus liver, exposed to pyrene.
  • Britigan BE et al: Uptake of lactoferrin by mononuclear phagocytes inhibits their ability to form hydroxyl radical and protects them from membrane autoperoxidation.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706298817.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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49. ||||||||.. 81%  Drouin BJ: Isotopic spectra of the hydroxyl radical. J Phys Chem A; 2013 Oct 3;117(39):10076-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isotopic spectra of the hydroxyl radical.
  • Rotational spectra of OH and its isotopologues have been precisely measured using high efficiency terahertz (THz) sources.
  • For the first time, microwave measurements of the Λ-doubling transitions of the (17)OH isotopologue are combined with THz data successfully.
  • Precise rotational, fine-structure, and hyperfine structure parameters for the (17)OH isotopologue are reported.
  • An isotopically independent Dunham model for all isotopologues of (2)Π OH v < 3 is presented.

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 23634899.001).
  • [ISSN] 1520-5215
  • [Journal-full-title] The journal of physical chemistry. A
  • [ISO-abbreviation] J Phys Chem A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. ||||||||.. 81%  Li K, Zhang P, Ge L, Ren H, Yu C, Chen X, Zhao Y: Concentration-dependent photodegradation kinetics and hydroxyl-radical oxidation of phenicol antibiotics. Chemosphere; 2014 Sep;111:278-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concentration-dependent photodegradation kinetics and hydroxyl-radical oxidation of phenicol antibiotics.
  • The present study investigated their photodegradation kinetics, hydroxyl-radical (OH) oxidation reactivities and products.
  • Secondly, the reaction between the phenicol antibiotics and OH was examined with a competition kinetic method under simulated solar irradiation (λ>290nm), which quantified their bimolecular reaction rate constants of (2.13±0.02)×10(9)M(-1)s(-1) and (1.82±0.10)×10(9)M(-1)s(-1) for thiamphenicol and florfenicol, respectively.
  • Then the corresponding OH oxidated half-lives in sunlit surface waters were calculated to be 90.5-106.1h.
  • Some main intermediates were formed from the reaction, which suggested that the two phenicols underwent hydroxylation, oxygenation and dehydrogenation when OH existed.

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  • [Copyright] Copyright © 2014 Elsevier Ltd. All rights reserved.
  • (PMID = 24997929.001).
  • [ISSN] 1879-1298
  • [Journal-full-title] Chemosphere
  • [ISO-abbreviation] Chemosphere
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Keywords] NOTNLM ; Competition kinetics / Phenicol antibiotics / Photolysis / Photooxidation / Transformation products
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