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1. Biomedical articles (top 50; 2008 to 2013)

1. |||||||||. 100%  Ciribassi J: Understanding behavior: feline hyperesthesia syndrome. Compend Contin Educ Vet; 2009;31(3):116-32

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Understanding behavior: feline hyperesthesia syndrome.

The etiology of feline hyperesthesia syndrome can be difficult to determine.

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(PMID = 19412901.001).

[ISSN] 1940-8315

[Journal-full-title] Compendium (Yardley, PA)

[ISO-abbreviation] Compend Contin Educ Vet

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

2. ||||||||.. 82%  Situ P, Simpson TL, Jones LW, Fonn D: Conjunctival and corneal hyperesthesia in subjects with dryness symptoms. Optom Vis Sci; 2008 Sep;85(9):867-72

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Conjunctival and corneal hyperesthesia in subjects with dryness symptoms.

PURPOSE: To compare conjunctival and corneal sensitivity in noncontact lens wearing subjects with and without symptoms of ocular dryness, stratified by age and gender.

A single score for the symptom of dryness was used to classify nondry eye (scores of none to trace) and dry eye symptomatic (scores of mild to severe) groups.

Conjunctival and corneal sensitivity of the right eye was measured at the central cornea and temporal conjunctiva, using a computer-controlled pneumatic esthesiometer with stimulus temperature set at 20 degrees C.

CONCLUSIONS: Conjunctival and corneal sensitivity to pneumatic cool stimulation is increased in subjects with symptoms of ocular dryness.

This hyperesthesia seems to be more significant in the conjunctiva.

[MeSH-major] Conjunctival Diseases / physiopathology. Corneal Diseases / physiopathology. Dry Eye Syndromes / physiopathology. Hyperesthesia / physiopathology

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(PMID = 18772722.001).

[ISSN] 1538-9235

[Journal-full-title] Optometry and vision science : official publication of the American Academy of Optometry

[ISO-abbreviation] Optom Vis Sci

[Language] eng

[Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

3. |||||||... 70%  Wesley CK, Unger RH, Rosenberg M, Unger MA, Unger WP: Factors influencing postoperative hyperesthesia in hair restoration surgery. J Cosmet Dermatol; 2011 Dec;10(4):301-6

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Factors influencing postoperative hyperesthesia in hair restoration surgery.

We investigated the technical and demographic variables that may contribute to the frequency of postoperative hyperesthesia.

RESULTS:   A total of 19 patients (3.4%) reported postoperative hyperesthesia in either the donor or recipient area of their scalp.

Although many trends emerged, one variable significantly influenced the rate of this neurosensory symptom.

While no patient who had all previous and current HRS sessions performed entirely within the same investigated surgical practice (n=42) experienced postoperative hyperesthesia, 14% of our patients who underwent prior HRS by a physician outside of the investigated surgical group (n=35) developed this complication (P=0.0404).

The amount of intraoperative electrocautery to maintain hemostasis (P=0.0897), degree of tension upon donor wound closure (P=0.3044), and extent of donor wound edge undermining (P=0.4420) influenced the frequency of this sequela to a lesser degree.

CONCLUSION:   These results suggest that physicians planning repair sessions on patients who have undergone prior HRS by a physician at a different surgical center should include the specific caveat of increased incidences of postoperative hyperesthesia in their preoperative consultation.

[MeSH-major] Cosmetic Techniques / adverse effects. Hair Follicle / transplantation. Hyperesthesia / etiology. Scalp / surgery

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[Copyright] © 2011 Wiley Periodicals, Inc.

(PMID = 22151939.001).

[ISSN] 1473-2165

[Journal-full-title] Journal of cosmetic dermatology

[ISO-abbreviation] J Cosmet Dermatol

[Language] eng

[Publication-type] Journal Article; Multicenter Study

[Publication-country] England

   

4. |||||||... 66%  Waldinger MD, Venema PL, van Gils AP, Schweitzer DH: New insights into restless genital syndrome: static mechanical hyperesthesia and neuropathy of the nervus dorsalis clitoridis. J Sex Med; 2009 Oct;6(10):2778-87

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] New insights into restless genital syndrome: static mechanical hyperesthesia and neuropathy of the nervus dorsalis clitoridis.

The localizations of genital sensations were investigated by physical examination of the ramus inferior of the pubic bone (RIPB) and by sensory testing of the skin of the genital area with a cotton swab (genital tactile mapping test or GTM test).

MAIN OUTCOME MEASURES: Sensitivity of RIPB, GTM test.

RESULTS: Of 23 women included in the study, 18(78%), 16(69%), and 12(52%) reported restless legs syndrome, overactive bladder syndrome, and urethra hypersensitivity.

Finger touch investigation of the dorsal nerve of the clitoris (DNC) along the RIPB provoked ReGS in all women.

Sensory testing showed unilateral and bilateral static mechanical Hyperesthesia on various trigger points in the dermatome of the pudendal nerve, particularly in the part innervated by DNC, including pelvic bone.

Physical examination for static mechanical Hyperesthesia is a diagnostic test for ReGS and is recommended for all individuals with complaints of persistent restless genital arousal in absence of sexual desire.

[MeSH-major] Clitoris / physiopathology. Hyperesthesia / complications. Peripheral Nervous System Diseases / complications. Sexual Dysfunction, Physiological / etiology

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(PMID = 19732313.001).

[ISSN] 1743-6109

[Journal-full-title] The journal of sexual medicine

[ISO-abbreviation] J Sex Med

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

5. ||||||.... 58%  Graven-Nielsen T, Wodehouse T, Langford RM, Arendt-Nielsen L, Kidd BL: Normalization of widespread hyperesthesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement. Arthritis Rheum; 2012 Sep;64(9):2907-16

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Normalization of widespread hyperesthesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement.

OBJECTIVE: The modest association between radiographic joint damage and pain in osteoarthritis (OA) has led to the suggestion of facilitated central pain processing.

This study evaluated the importance of ongoing tissue pathology in the maintenance of enhanced central pain processing.

METHODS: Pain assessment was performed on 48 patients with symptomatic knee OA and 21 sex- and age-matched pain-free healthy control subjects.

Pressure-pain thresholds (PPTs) were recorded using a pressure algometer (both over and distant from the knee) and a double-chamber inflatable cuff mounted around the calf.

Conditioned pain modulation (CPM) was assessed by recording the increase in PPT in response to experimental arm pain.

RESULTS: PPTs at the knee and at sites away from the knee were reduced in OA patients as compared with healthy pain-free control subjects (P < 0.0001).

Whereas an elevation of PPTs was noted in the healthy controls in response to experimental arm pain (P < 0.0001), no such CPM was observed in the OA patients.

Following joint replacement in the OA patients, there was a reduction in the widespread mechanical hyperesthesia, along with normalization of spatial summation ratios and restoration of CPM.

CONCLUSION: The widespread hyperesthesia and enhanced spatial summation observed in OA patients imply sensitized central pain mechanisms together with the loss of CPM.

Normalization of the results following joint replacement implies that these central pain processes are maintained by peripheral input.

[MeSH-major] Arthroplasty, Replacement, Knee. Hyperesthesia / surgery. Knee Joint / surgery. Nociceptive Pain / surgery. Osteoarthritis, Knee / surgery

[MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Pain Measurement. Treatment Outcome

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[Copyright] Copyright © 2012 by the American College of Rheumatology.

[CommentIn] Nat Rev Rheumatol. 2012 May;8(5):246 [22549278.001]

[CommentIn] Arthritis Rheum. 2012 Dec;64(12):4165; author reply 4165-6 [22941902.001]

(PMID = 22421811.001).

[ISSN] 1529-0131

[Journal-full-title] Arthritis and rheumatism

[ISO-abbreviation] Arthritis Rheum.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

6. ||||...... 39%  Zhou XZ: [Hyperesthesia of back induced by cervical spondylopathy]. Zhongguo Gu Shang; 2010 Sep;23(9):722

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Hyperesthesia of back induced by cervical spondylopathy].

[MeSH-major] Cervical Vertebrae. Hyperesthesia / etiology. Spondylosis / complications

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(PMID = 20964013.001).

[ISSN] 1003-0034

[Journal-full-title] Zhongguo gu shang = China journal of orthopaedics and traumatology

[ISO-abbreviation] Zhongguo Gu Shang

[Language] chi

[Publication-type] Case Reports; Journal Article

[Publication-country] China

   

7. |||....... 31%  Marek I, Metzler M, Reutter G, Holter W: Recurrent fever episodes with arthralgia or hyperesthesia--have you ruled out parvovirus B19? Klin Padiatr; 2010 Nov;222(6):397-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Recurrent fever episodes with arthralgia or hyperesthesia--have you ruled out parvovirus B19?

[MeSH-major] Arthralgia / etiology. Erythema Infectiosum / diagnosis. Fever of Unknown Origin / etiology. Hyperesthesia / etiology. Parvovirus B19, Human

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(PMID = 20806168.001).

[ISSN] 1439-3824

[Journal-full-title] Klinische Pädiatrie

[ISO-abbreviation] Klin Padiatr

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Germany

   

8. |......... 13%  Markos AR: Caffeine-related genital skin pain. J Low Genit Tract Dis; 2008 Jan;12(1):38-9

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Caffeine-related genital skin pain.

Genital hyperesthesia is more recognized in women but may affect men.

We report both a female and a male patient in whom caffeine intake was associated with genital hyperesthesia.

[MeSH-major] Caffeine / adverse effects. Central Nervous System Stimulants / adverse effects. Genital Diseases, Female / chemically induced. Pain / chemically induced. Penile Diseases / chemically induced. Skin Diseases / chemically induced

[MeSH-minor] Adolescent. Aged. Coffee / adverse effects. Female. Humans. Hyperesthesia / chemically induced. Male

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(PMID = 18162812.001).

[ISSN] 1089-2591

[Journal-full-title] Journal of lower genital tract disease

[ISO-abbreviation] J Low Genit Tract Dis

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Central Nervous System Stimulants; 0 / Coffee; 58-08-2 / Caffeine

   

9. |......... 6%  Vartiainen NV, Kirveskari E, Forss N: Central processing of tactile and nociceptive stimuli in complex regional pain syndrome. Clin Neurophysiol; 2008 Oct;119(10):2380-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Central processing of tactile and nociceptive stimuli in complex regional pain syndrome.

OBJECTIVE: Patients with complex regional pain syndrome (CRPS) suffer from continuous regional limb pain and from hyperesthesia to touch and pain.

To better understand the pathophysiological mechanisms underlying the hyperesthesia of CRPS patients, we investigated their cortical processing of touch and acute pain.

The PPC source strength correlated with the pain rating in the control subjects, but not in the patients.

CONCLUSIONS: The enhanced SI activation in hyperesthetic CRPS patients may reflect central sensitization to touch.

As the SII and PPC responses were not enhanced in the CRPS patients, other brain areas are likely to contribute to the observed hyperesthesia to pain.

[MeSH-major] Brain Mapping. Cerebral Cortex / physiopathology. Complex Regional Pain Syndromes / pathology. Evoked Potentials / physiology. Pain Threshold / physiology

[MeSH-minor] Afferent Pathways / physiopathology. Dose-Response Relationship, Radiation. Electroencephalography / methods. Functional Laterality. Humans. Hyperesthesia / physiopathology. Lasers / adverse effects. Magnetic Resonance Imaging. Pain Measurement / methods. Physical Stimulation / methods. Reaction Time / physiology

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(PMID = 18723393.001).

[ISSN] 1388-2457

[Journal-full-title] Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

[ISO-abbreviation] Clin Neurophysiol

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Netherlands

   

10. |......... 6%  Waldinger MD, Venema PL, van Gils AP, de Lint GJ, Schweitzer DH: Stronger evidence for small fiber sensory neuropathy in restless genital syndrome: two case reports in males. J Sex Med; 2011 Jan;8(1):325-30

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

INTRODUCTION: Restless genital syndrome (ReGS) is characterized by unwanted, unpleasant genital sensations, restless legs, and/or overactive bladder, as well as neuropathy of the dorsal nerve of the clitoris.

METHODS: Two males with unwanted genital sensations presented in our clinic.

RESULTS: ReGS in a 74-year-old male manifested as unpleasant genital sensations of being on the edge of an orgasm with overactive bladder, in the absence of erection and ejaculation.

Genital sensory testing elicited bilateral points of static mechanical hyperesthesia in the pudendal dermatome.

Manual examination of the dorsal nerve of the penis (DNP) elicited the genital sensations.

TENS application resulted in a 90% reduction of genital sensations and complaints of overactive bladder syndrome (OAB).

Genital sensory testing elicited bilateral points of static mechanical hyperesthesia in the pudendal dermatome.

Manual examination of the DNP elicited the genital sensations.

This notion and the finding of typical sensory abnormalities of the genital end branches of the pudendal nerve in males and females--as previously reported--provides strong evidence for Small Fiber Sensory Neuropathy as a common cause of ReGS.

[MeSH-major] Hyperesthesia. Peripheral Nervous System Diseases. Restless Legs Syndrome. Sexual Dysfunction, Physiological. Urinary Bladder, Overactive

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[Copyright] © 2010 International Society for Sexual Medicine.

(PMID = 20955316.001).

[ISSN] 1743-6109

[Journal-full-title] The journal of sexual medicine

[ISO-abbreviation] J Sex Med

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

11. |......... 6%  Ait Benhaddou E, Zinebi A, Elhassani M, Raissouni L, Elhassani MR, Benomar A, Yahyaoui M: [Pachymeningitis associated with probable Horton's disease: a case report]. Rev Neurol (Paris); 2010 Feb;166(2):253-6

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Pachymeningitis associated with probable Horton's disease: a case report].

INTRODUCTION: Horton's disease is the most common vasculitis of elder people.

OBSERVATION: A 71-year-old patient who presented headache, hyperesthesia of the scalp, weight loss with a biological inflammatory syndrome and meningeal thickening on MRI.

The diagnosis of pachymeningitis related to Horton's disease was retained.

CONCLUSION: Horton's disease is a potential diagnosis in elderly persons with pachymeningitis and inflammatory syndrome.

[MeSH-minor] Aged. Dura Mater / pathology. Female. Headache / etiology. Humans. Hyperesthesia / drug therapy. Hyperesthesia / etiology. Inflammation / pathology. Magnetic Resonance Imaging. Meninges / anatomy & histology. Meninges / drug effects. Meninges / pathology. Meningitis / etiology. Scalp / physiopathology

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[Copyright] Copyright 2009. Published by Elsevier Masson SAS.

(PMID = 19497602.001).

[ISSN] 0035-3787

[Journal-full-title] Revue neurologique

[ISO-abbreviation] Rev. Neurol. (Paris)

[Language] fre

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] France

[Chemical-registry-number] 0 / Adrenal Cortex Hormones

   

12. |......... 6%  Williams ST, Davies A, Bryson P: Chronic regional pain syndrome after subtalar arthrodesis is not prevented by early hyperbaric oxygen. Pain Physician; 2009 Sep-Oct;12(5):E335-9

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Chronic regional pain syndrome after subtalar arthrodesis is not prevented by early hyperbaric oxygen.

Subtalar arthrodesis was performed on a 48-year-old, non-insulin-dependent diabetic with a history of chronic ankle instability and lateral ankle pain.

By 7 weeks after emergency admission his wounds had virtually healed but hyperesthesia persisted over the dorsum of the foot.

Symptoms and signs at this time were compatible with a diagnosis of chronic regional pain syndrome (CRPS).

[MeSH-major] Arthrodesis / adverse effects. Complex Regional Pain Syndromes / etiology. Hyperbaric Oxygenation. Pain, Postoperative / etiology. Subtalar Joint / surgery. Surgical Wound Infection / therapy

[MeSH-minor] Diabetes Complications / physiopathology. Foot / innervation. Foot / physiopathology. Humans. Hyperesthesia / etiology. Hyperesthesia / physiopathology. Hyperesthesia / therapy. Joint Instability / surgery. Male. Middle Aged. Tomography, X-Ray Computed. Treatment Failure. Wound Healing / physiology

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(PMID = 19787019.001).

[ISSN] 2150-1149

[Journal-full-title] Pain physician

[ISO-abbreviation] Pain Physician

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

13. |......... 6%  Fessa CK, Lee BS: An Australian case of surfer's myelopathy. Clin J Sport Med; 2012 May;22(3):281-3

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

We present a 19-year-old man who developed lower back pain, profound bilateral lower limb paraparesis, and hyperesthesia during his first learn to surf class.

[MeSH-minor] Analgesics / therapeutic use. Australia. Humans. Hyperesthesia / diagnosis. Low Back Pain / diagnosis. Low Back Pain / drug therapy. Magnetic Resonance Imaging. Male. Paraparesis / diagnosis. Paraplegia / diagnosis. Severity of Illness Index. Spinal Cord Ischemia / diagnosis. Young Adult

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(PMID = 22544059.001).

[ISSN] 1536-3724

[Journal-full-title] Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

[ISO-abbreviation] Clin J Sport Med

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Analgesics

   

14. |......... 5%  Griffin JF, Levine J, Kerwin S, Cole R: Canine thoracolumbar invertebral disk disease: diagnosis, prognosis, and treatment. Compend Contin Educ Vet; 2009;31(3):E1-E14

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Canine thoracolumbar invertebral disk disease: diagnosis, prognosis, and treatment.

Thoracolumbar intervertebral disk disease (IVDD) is a common, important cause of paraspinal hyperesthesia, pelvic limb ataxia, paraparesis, paraplegia, and urinary and fecal incontinence in dogs.

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(PMID = 19412898.001).

[ISSN] 1940-8315

[Journal-full-title] Compendium (Yardley, PA)

[ISO-abbreviation] Compend Contin Educ Vet

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

15. |......... 5%  Balakrishnan C, Mussman JL, Balakrishnan A, Khalil AJ: Acute carpal tunnel syndrome from burns of the hand and wrist. Can J Plast Surg; 2009;17(4):e33-4

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Acute median nerve compression usually occurs from increased pressure within the carpal tunnel and forearm compartments.

Although the hyperesthesia from burns may mimic symptoms of acute compression neuropathy, clinical diagnosis should be made from history, clinical signs and symptoms.

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(PMID = 21119830.001).

[ISSN] 1918-1507

[Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique

[ISO-abbreviation] Can J Plast Surg

[Language] eng

[Publication-type] Journal Article

[Publication-country] Canada

[Other-IDs] NLM/ PMC2827286

   

16. |......... 5%  Mbelesso P, Yogo ML, Yangatimbi E, Paul-Sénékian Vd, Nali NM, Preux PM: [Outbreak of konzo disease in health region No. 2 of the Central African Republic]. Rev Neurol (Paris); 2009 May;165(5):466-70

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] [Outbreak of konzo disease in health region No. 2 of the Central African Republic].

INTRODUCTION: Konzo is a neuromyelopathy characterized by permanent spastic paraparesis, linked to a subacute poisoning by cyanide found in cassava.

The predominant neurological signs were lower limb paresis (90.0%) and hyperesthesia (66.7%).

[MeSH-minor] Adolescent. Central African Republic / epidemiology. Child. Child, Preschool. Disease Outbreaks. Female. Humans. Hyperesthesia / etiology. Male. Vision Disorders / etiology. Visual Acuity

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(PMID = 19081587.001).

[ISSN] 0035-3787

[Journal-full-title] Revue neurologique

[ISO-abbreviation] Rev. Neurol. (Paris)

[Language] fre

[Publication-type] English Abstract; Journal Article

[Publication-country] France

   

17. |......... 5%  En J, Goto M, Nakanaga K, Higashi M, Ishii N, Saito H, Yonezawa S, Hamada H, Small PL: Mycolactone is responsible for the painlessness of Mycobacterium ulcerans infection (buruli ulcer) in a murine study. Infect Immun; 2008 May;76(5):2002-7

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Buruli ulcer is a chronic skin disease caused by Mycobacterium ulcerans, which produces a toxic lipid mycolactone.

This absence of pain prevents patients from seeking early treatment and, as a result, many patients experience severe sequelae, including limb amputation.

We have reported that mice inoculated with M. ulcerans show loss of pain sensation and nerve degeneration.

The von Frey sensory test showed hyperesthesia on day 7, recovery on day 21, and hypoesthesia on day 28.

This study demonstrated that initial hyperesthesia is followed by sensory recovery and final hypoesthesia.

Our present study suggests that mycolactone directly damages nerves and is responsible for the absence of pain characteristic of Buruli ulcer.

[MeSH-minor] Animals. Female. Foot / pathology. Hemorrhage. Hyperesthesia. Lung / pathology. Macrolides. Mice. Mice, Inbred BALB C. Necrosis / pathology. Nerve Tissue / drug effects. Nerve Tissue / pathology. Nerve Tissue / physiopathology. Skin Ulcer / pathology. Time Factors

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[Cites] Infect Immun. 2000 Feb;68(2):877-83 [10639458.001]

[Cites] Infect Immun. 2001 Nov;69(11):7182-6 [11598099.001]

[Cites] Clin Infect Dis. 2003 Sep 15;37(6):e78-82 [12955667.001]

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(PMID = 18316387.001).

[ISSN] 1098-5522

[Journal-full-title] Infection and immunity

[ISO-abbreviation] Infect. Immun.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

[Chemical-registry-number] 0 / Analgesics; 0 / Bacterial Toxins; 0 / Macrolides; 0 / mycolactone

[Other-IDs] NLM/ PMC2346717

   

18. |......... 5%  Brunner F, Lienhardt SB, Kissling RO, Bachmann LM, Weber U: Diagnostic criteria and follow-up parameters in complex regional pain syndrome type I--a Delphi survey. Eur J Pain; 2008 Jan;12(1):48-52

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Diagnostic criteria and follow-up parameters in complex regional pain syndrome type I--a Delphi survey.

BACKGROUND: Although the current clinical guideline of diagnostic criteria for the complex regional pain syndrome I (CRPS I) is a landmark endeavour to define this complex condition it does not prioritise its most important clinical manifestations.

In three domains (clinical presentation, further examinations and follow-up) experts agreed on the following parameters, pain (10; 9-10) with its subcategories hyperesthesia (7; 5-8) hyperalgesia (8; 8-8) and allodynia (8; 7-10), signs with oedema (9; 8-10) and colour change (8; 5-8) and mobility with its categories motor change (7; 5-8) and decreased range of motion (8; 8-8).

The agreed important follow-up parameter was clinical course (10; 8-10) with its categories decrease in pain (8; 8-9) and hyperalgesia (8; 6-8), decreased oedema (8; 7-10) and improvements in motor function (10; 8-10) and strength (8; 6-9).

[MeSH-minor] Edema / etiology. Expert Testimony. Follow-Up Studies. Humans. Hyperalgesia / physiopathology. Hyperesthesia / physiopathology. Movement. Muscle Strength. Pain Measurement. Range of Motion, Articular

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(PMID = 17400492.001).

[ISSN] 1532-2149

[Journal-full-title] European journal of pain (London, England)

[ISO-abbreviation] Eur J Pain

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

   

19. |......... 5%  Kumar R, Aggarwal A, Faridi MM: Complex regional pain syndrome type 1 and scurvy. Indian Pediatr; 2009 Jun;46(6):529-31

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Complex regional pain syndrome type 1 and scurvy.

A 5 year old female developed features of complex regional pain syndrome (CRPS) i.e excessive pain to touch, decreased sweating and edema of left ankle 2 years after fracture of left tibia.

Hyperesthesia improved and child walked with support following administration of vitamin C.

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(PMID = 19556664.001).

[ISSN] 0019-6061

[Journal-full-title] Indian pediatrics

[ISO-abbreviation] Indian Pediatr

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] India

[Chemical-registry-number] 0 / Vitamins; 50-81-7 / Ascorbic Acid

   

20. |......... 5%  Park C, Kang BT, Yoo JH, Park HM: Syringomyelia in three small breed dogs secondary to Chiari-like malformation: clinical and diagnostic findings. J Vet Sci; 2009 Dec;10(4):365-7

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Upon physical and neurologic examination, all dogs displayed hyperesthesia, pain, and neck stiffness.

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[Cites] Vet J. 2008 Feb;175(2):164-72 [17317245.001]

[Cites] J Small Anim Pract. 2007 Aug;48(8):432-6 [17608656.001]

[Cites] Vet Surg. 2007 Jul;36(5):396-405 [17614920.001]

[Cites] J Vet Intern Med. 2006 May-Jun;20(3):469-79 [16734077.001]

[Cites] Aust Vet J. 2000 Feb;78(2):92-5 [10736666.001]

[Cites] J Am Vet Med Assoc. 2005 Oct 15;227(8):1270-5, 1250-1 [16266016.001]

[Cites] Neurosurgery. 1996 May;38(5):940-6; discussion 946-7 [8727819.001]

[Cites] Methods Mol Med. 2004;99:139-53 [15131335.001]

[Cites] J Neurosurg. 2004 Mar;100(3 Suppl Spine):241-4 [15029911.001]

[Cites] J Small Anim Pract. 2005 Jun;46(6):265-72 [15971896.001]

(PMID = 19934606.001).

[ISSN] 1976-555X

[Journal-full-title] Journal of veterinary science

[ISO-abbreviation] J. Vet. Sci.

[Language] eng

[Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Korea (South)

[Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Diuretics; 50-24-8 / Prednisolone; 54-31-9 / Furosemide

[Other-IDs] NLM/ PMC2807277

   

21. |......... 5%  Vieira AH, Santiago SL: Management of dentinal hypersensitivity. Gen Dent; 2009 Mar-Apr;57(2):120-6; quiz 127-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Management of dentinal hypersensitivity.

Dentinal hypersensitivity is a complex condition that can cause considerable concern in the dental office.

Selecting the right therapy requires a complete understanding of how applying a stimulus to the exposed dentin surface can influence the nerve fibers and produce hyperesthesia.

This article reviews the etiology and critically analyzes management of dentinal hypersensitivity by reviewing laboratory and clinical investigations.

[MeSH-major] Dentin Sensitivity / therapy

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(PMID = 19552361.001).

[ISSN] 0363-6771

[Journal-full-title] General dentistry

[ISO-abbreviation] Gen Dent

[Language] eng

[Publication-type] Journal Article; Review

[Publication-country] United States

[Number-of-references] 47

   

22. |......... 4%  Ahmed Z, Powell R, Llewelyn G, Anstey A: Chronic inflammatory demyelinating polyradiculoneuropathy complicating anti TNF α therapy for chronic plaque psoriasis. BMJ Case Rep; 2011;2011

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A 53-year-old woman with chronic plaque psoriasis treated with adalimumab (antitumour necrosis factor (anti TNF) α therapy) for 10 months presented with an 8 week history of hyperesthesia in a 'glove and stocking' distribution and clumsiness on walking.

Nerve conduction studies confirmed the clinical diagnosis of a chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).

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(PMID = 22674940.001).

[ISSN] 1757-790X

[Journal-full-title] BMJ case reports

[ISO-abbreviation] BMJ Case Rep

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

23. |......... 4%  Waldinger MD, Venema PL, van Gils AP, Schutter EM, Schweitzer DH: Restless genital syndrome before and after clitoridectomy for spontaneous orgasms: a case report. J Sex Med; 2010 Feb;7(2 Pt 2):1029-34

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

INTRODUCTION: Females despairing of restless genital syndrome (ReGS) may request clitoridectomy for treatment of unwanted genital sensations. Aim.

METHODS: Following a clitoridectomy for spontaneous orgasms, a 77-year-old woman was referred to our clinic for persistent unwanted genital sensations and feelings of imminent orgasm.

The localizations of genital sensations were investigated by manual examination of the ramus inferior of the pubic bone (RIPB) and by sensory testing of the skin of the genital area with a cotton swab.

MAIN OUTCOME MEASURES: The main outcome measures included sensitivity of dorsal nerve of the clitoris in RIPB and MRI-pelvis.

Sensory testing of the genital area showed various points of static mechanical hyperesthesia at the left dermatome of the pudendal nerve.

Manual examination of the RIPB also elicited the genital sensations at the left side of the vagina at about the 3 o'clock position.

[MeSH-major] Circumcision, Female. Genitalia, Female / physiopathology. Sensation Disorders / etiology. Sexual Dysfunctions, Psychological / surgery

[MeSH-minor] Aged. Clitoris / innervation. Clitoris / pathology. Clitoris / physiopathology. Electroencephalography. Female. Humans. Hyperesthesia / surgery. Magnetic Resonance Imaging. Pubic Bone / innervation. Syndrome. Time Factors

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(PMID = 19912500.001).

[ISSN] 1743-6109

[Journal-full-title] The journal of sexual medicine

[ISO-abbreviation] J Sex Med

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

24. |......... 4%  Griffin JF, Levine J, Kerwin S: Canine thoracolumbar invertebral disk disease: pathophysiology, neurologic examination, and emergency medical therapy. Compend Contin Educ Vet; 2009;31(3):E1-E13

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Canine thoracolumbar invertebral disk disease: pathophysiology, neurologic examination, and emergency medical therapy.

Thoracolumbar intervertebral disk disease (IVDD) is a common, important cause of paraspinal hyperesthesia, pelvic limb ataxia, paraparesis, paraplegia, and urinary and fecal incontinence in dogs.

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(PMID = 19412899.001).

[ISSN] 1940-8315

[Journal-full-title] Compendium (Yardley, PA)

[ISO-abbreviation] Compend Contin Educ Vet

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

25. |......... 4%  Fernández-de-Las-Peñas C, Cuadrado ML, Arendt-Nielsen L, Pareja JA: Side-to-side differences in pressure pain thresholds and pericranial muscle tenderness in strictly unilateral migraine. Eur J Neurol; 2008 Feb;15(2):162-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Side-to-side differences in pressure pain thresholds and pericranial muscle tenderness in strictly unilateral migraine.

Previous studies dealing with pressure pain sensitivity or muscle tenderness in migraine have shown conflicting results.

Our aim was to explore the differences in mechanical pain sensitivity and pericranial muscle tenderness between patients with unilateral migraine and healthy controls, and to analyse side-to-side differences in both study groups.

Pressure pain thresholds (PPT) at cephalic and neck points, plus local and total tenderness scores were blindly assessed in 25 patients with strictly unilateral migraine and 25 healthy subjects.

Patients had lower PPT and increased pericranial tenderness on the symptomatic side as compared with the non-symptomatic side and to either side in controls (P < 0.001), whereas no significant differences were identified between the non-symptomatic side and controls (P > 0.9).

The enhancement of local tenderness scores was related to hyperesthesia of specific muscles (sternocleidomastoid, suboccipital, and temporalis) rather than a generalized pericranial tenderness.

[MeSH-major] Migraine Disorders / physiopathology. Muscle, Skeletal / physiopathology. Pain Threshold

[MeSH-minor] Adult. Female. Head. Humans. Hyperesthesia / physiopathology. Male. Neck. Pain / physiopathology. Pressure. Single-Blind Method. Skull

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(PMID = 18093151.001).

[ISSN] 1468-1331

[Journal-full-title] European journal of neurology : the official journal of the European Federation of Neurological Societies

[ISO-abbreviation] Eur. J. Neurol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

26. |......... 4%  Havton LA: A lumbosacral ventral root avulsion injury and repair model for studies of neuropathic pain in rats. Methods Mol Biol; 2012;851:185-93

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] A lumbosacral ventral root avulsion injury and repair model for studies of neuropathic pain in rats.

Neuropathic pain may develop after a variety of injuries to peripheral nerves and roots.

Recently, it has been demonstrated that injury to motor fibers in ventral roots may also result in neuropathic pain.

A lumbosacral ventral root avulsion injury results in acute and persistent mechanical allodynia, but not thermal hyperesthesia.

Interestingly, an acute replantation of the avulsed ventral roots into the spinal cord results in amelioration of the neuropathic pain.

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(PMID = 22351091.001).

[ISSN] 1940-6029

[Journal-full-title] Methods in molecular biology (Clifton, N.J.)

[ISO-abbreviation] Methods Mol. Biol.

[Language] eng

[Grant] United States / NINDS NIH HHS / NS / NS042719

[Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

27. |......... 4%  Richardson BS, Way BV, Speece AJ 3rd: Osteopathic manipulative treatment in the management of notalgia paresthetica. J Am Osteopath Assoc; 2009 Nov;109(11):605-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Symptoms may include pain, hyperesthesia, paresthesia, and hyperpigmentation of the affected area.

The authors report the case of a 59-year-old woman with notalgia paresthetica who received one 20-minute session of osteopathic manipulative treatment that focused primarily on thoracic spine and rib somatic dysfunctions.

[MeSH-major] Back Pain / therapy. Manipulation, Osteopathic. Paresthesia / therapy

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(PMID = 19948695.001).

[ISSN] 1945-1997

[Journal-full-title] The Journal of the American Osteopathic Association

[ISO-abbreviation] J Am Osteopath Assoc

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

28. |......... 4%  De Decker S, De Risio L, Lowrie M, Mauler D, Beltran E, Giedja A, Kenny PJ, Gielen I, Garosi L, Volk H: Cervical vertebral stenosis associated with a vertebral arch anomaly in the Basset Hound. J Vet Intern Med; 2012 Nov-Dec;26(6):1374-82

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

OBJECTIVES: To report the clinical presentation, imaging characteristics, treatment results, and histopathological findings of a previously undescribed vertebral malformation in the Basset Hound.

Eighteen Basset Hounds presented for evaluation of a suspected cervical spinal cord problem.

Clinical signs varied from cervical hyperesthesia to nonambulatory tetraparesis.

CONCLUSIONS AND CLINICAL IMPORTANCE: Dorsal lamina and spinous process hypertrophy leading to ligamentum flavum hypertrophy should be included in the differential diagnosis of Basset Hounds with cervical hyperesthesia or myelopathy.

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[Copyright] Copyright © 2012 by the American College of Veterinary Internal Medicine.

(PMID = 22978330.001).

[ISSN] 1939-1676

[Journal-full-title] Journal of veterinary internal medicine / American College of Veterinary Internal Medicine

[ISO-abbreviation] J. Vet. Intern. Med.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

29. |......... 4%  Wildgaard K, Ringsted TK, Aasvang EK, Ravn J, Werner MU, Kehlet H: Neurophysiological characterization of persistent postthoracotomy pain. Clin J Pain; 2012 Feb;28(2):136-42

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Neurophysiological characterization of persistent postthoracotomy pain.

OBJECTIVES: The postthoracotomy pain syndrome (PTPS) has a prevalence of 30% to 40%.

Although intraoperative nerve damage during thoracotomy has been demonstrated, it has not been clearly linked to PTPS and detailed quantitative sensory characterization data have so far not been presented, comparing PTPS and pain-free patients.

METHODS: Neurophysiological characterization was performed in 17 patients with PTPS and 24 pain-free postthoracotomy patients using a detailed quantitative sensory testing protocol and psychometric questionnaires.

RESULTS: Pain and pain-free patients had increased thresholds to tactile detection (P=0.001 and P=0.01) and cool detection (P<0.001 and P<0.01) on the operated side versus the contralateral side.

Pain patients also had increased thresholds for warmth detection (P<0.001) and heat pain (P<0.01) on the operated side.

The PTPS patients demonstrated increased side-to-side differences for warmth detection (P<0.01), heat pain (P<0.05), and cool detection (P<0.05) thresholds compared with pain-free patients.

Pain patients also more frequently experienced cool hyperesthesia (8 of 17 vs. 1 of 24, P<0.01), but no differences were found for pressure pain, temporal summation, or sensory mapping to cool (200 cm vs. 76 cm, P=0.18).

Hospital Anxiety and Depression Scale scores were higher for PTPS than for pain-free patients (P<0.01).

DISCUSSION: Neurophysiological assessments indicate nerve injury to be common in pain and pain-free patients after thoracotomy.

The combination of increased thresholds together with hyperesthesia, suggests consequences of nerve injury to be more pronounced in PTPS patients.

[MeSH-major] Chest Pain / diagnosis. Chest Pain / etiology. Chest Pain / physiopathology. Chronic Pain / etiology. Chronic Pain / physiopathology. Pain Measurement / methods. Thoracotomy / adverse effects

[MeSH-minor] Adult. Aged. Chronic Disease. Female. Humans. Male. Middle Aged

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(PMID = 21705872.001).

[ISSN] 1536-5409

[Journal-full-title] The Clinical journal of pain

[ISO-abbreviation] Clin J Pain

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

30. |......... 4%  Situ P, Simpson TL, Fonn D, Jones LW: Conjunctival and corneal pneumatic sensitivity is associated with signs and symptoms of ocular dryness. Invest Ophthalmol Vis Sci; 2008 Jul;49(7):2971-6

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Conjunctival and corneal pneumatic sensitivity is associated with signs and symptoms of ocular dryness.

PURPOSE: To investigate the relationships of dry eye symptoms and corneal and conjunctival sensitivity to pneumatic stimulation, tear film stability, and clinical ocular surface characteristics in symptomatic and asymptomatic subjects.

Symptoms were assessed according to the Ocular Surface Disease Index (OSDI).

Step-wise multiple regression analysis showed that ocular surface sensitivity and NIBUT were significant predictors of the OSDI.

CONCLUSIONS: Ocular irritation assessed with the OSDI is associated with ocular surface hyperesthesia to cooling, corneal epitheliopathy, and tear film instability.

[MeSH-minor] Adult. Aged. Aged, 80 and over. Air. Cold Temperature. Diagnosis, Computer-Assisted. Diagnostic Techniques, Ophthalmological. Epithelium, Corneal / pathology. Eye Diseases / etiology. Female. Humans. Hyperesthesia / etiology. Male. Middle Aged. Physical Stimulation. Tears / metabolism

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(PMID = 18390645.001).

[ISSN] 1552-5783

[Journal-full-title] Investigative ophthalmology & visual science

[ISO-abbreviation] Invest. Ophthalmol. Vis. Sci.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

31. |......... 4%  Tseng YT, Tsai HC, Sy CL, Lee SS, Wann SR, Wang YH, Chen JK, Wu KS, Chen YS: Clinical manifestations of eosinophilic meningitis caused by Angiostrongylus cantonensis: 18 years' experience in a medical center in southern Taiwan. J Microbiol Immunol Infect; 2011 Oct;44(5):382-9

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Most of the patients presented with headache (29, 78%), fever (25, 68%), and 11(30%) had hyperesthesia.

Patients with hyperesthesia had longer incubation period (55 vs. 7 days, p=0.004), lower serum immunoglobulin E levels (127.5 vs. 1295 IU/mL, p<0.001), and longer duration between symptom onset and spinal taps (14 vs. 5 days, p=0.011).

Magnetic resonance imaging of the brain disclosed leptomeningeal enhancement (17/26, 65%) and increased signal intensity (10/26, 38%) on T2-weighted and fluid-attenuated inversion recovery images.

Hyperesthesia; repeated lumbar puncture in cases with lymphocytic meningitis of uncertain cause; and a detailed history, including food consumption, are important to establish an accurate diagnosis.

[MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Animals. Child. Child, Preschool. Clinical Laboratory Techniques / methods. Disease Outbreaks. Female. Humans. Male. Middle Aged. Parasitology / methods. Retrospective Studies. Taiwan / epidemiology. Young Adult

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[Copyright] Copyright © 2011. Published by Elsevier B.V.

(PMID = 21524976.001).

[ISSN] 1995-9133

[Journal-full-title] Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

[ISO-abbreviation] J Microbiol Immunol Infect

[Language] eng

[Publication-type] Journal Article

[Publication-country] England

   

32. |......... 4%  Arribas-García I, Alcalá-Galiano A, Gutiérrez R, Montalvo-Moreno JJ: Traumatic neuroma of the inferior alveolar nerve: a case report. Med Oral Patol Oral Cir Bucal; 2008 Mar;13(3):E186-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Traumatic neuromas are rare entities which characteristically arise subsequently to surgery and are usually accompanied by pain, typically neuralgic.

A 56-year-old man consulted for paresthesias and hyperesthesia in the left mandibular region following extraction of the left mandibular third molar (#38).

The panoramic radiograph revealed a radiolucent lesion in the inferior alveolar nerve canal, and CT demonstrated the existence of a mass within the canal, producing widening of the same.

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(PMID = 18305440.001).

[ISSN] 1698-6946

[Journal-full-title] Medicina oral, patología oral y cirugía bucal

[ISO-abbreviation] Med Oral Patol Oral Cir Bucal

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Spain

   

33. |......... 4%  Fernández-Mayoralas DM, Fernández-Jaén A, Jareño NM, Pérez BC, Fernández PM, Sola AG: Meralgia paresthetica in the pediatric population: a propos of 2 cases. J Child Neurol; 2010 Jan;25(1):110-3

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Two adolescent females, aged 11 and 13 years, presented due to tingling and pain on the side of the thigh of 2 to 3 weeks duration.

The general examination revealed mild obesity; the neurological examination of both patients is normal except for pain, hypo- or hyperesthesia on the side of the quadriceps.

[MeSH-minor] Adolescent. Anti-Obesity Agents / therapeutic use. Child. Female. Follow-Up Studies. Fructose / analogs & derivatives. Fructose / therapeutic use. Humans. Muscle, Skeletal / physiopathology. Neural Conduction. Pain / diagnosis. Pain / physiopathology. Pain Management. Treatment Outcome

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(PMID = 19458380.001).

[ISSN] 1708-8283

[Journal-full-title] Journal of child neurology

[ISO-abbreviation] J. Child Neurol.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Anti-Obesity Agents; 30237-26-4 / Fructose; 97240-79-4 / topiramate

   

34. |......... 4%  Sunami K, Takayama M, Okabe Y, Yamane H, Tochino Y, Kodama T, Negoro N: [A case of Churg-Strauss syndrome following corticosteroid withdrawal]. Nihon Jibiinkoka Gakkai Kaiho; 2009 Jun;112(6):487-90

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

He then developed fever, maniphalanx stiffness, testicular pain, and facial hyperesthesia, eruptions, and the lower-limb numbness.

The detection of a positive serum reaction for MPO-ANCA and evaluated of eosinophilic leukocyte levels yielded a definitive diagnosis of CSS, for which the man was treated with predonisolone and cyclophosphamide.

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(PMID = 19610591.001).

[ISSN] 0030-6622

[Journal-full-title] Nihon Jibiinkoka Gakkai kaiho

[ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho

[Language] jpn

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Japan

[Chemical-registry-number] 0 / Glucocorticoids; 50-24-8 / Prednisolone

   

35. |......... 4%  Johansen A, Romundstad L, Nielsen CS, Schirmer H, Stubhaug A: Persistent postsurgical pain in a general population: prevalence and predictors in the Tromsø study. Pain; 2012 Jul;153(7):1390-6

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Persistent postsurgical pain in a general population: prevalence and predictors in the Tromsø study.

Population-based data on the prevalence of persistent postsurgical pain are scarce.

This study aimed to assess the prevalence of persistent postsurgical pain in a general population and to describe associated physical, social, and psychological factors, including symptoms of nerve injury and sensitization.

A cross-sectional survey was performed in northern Norway with questionnaire items covering surgery, pain, and sensory abnormalities in the area of surgery.

Persistent pain in the area of surgery was reported by 40.4% of the patients (826 of 2043), moderate or severe pain by 18.3% (373 of 2043).

Hypoesthesia, hyperesthesia, or both was reported by 24.5% (501 of 2043).

There were strong associations between sensory abnormalities and persistent pain, increasingly with higher pain intensities; odds ratios were 2.68 for hypoesthesia and 6.27 for hyperesthesia.

Of the 826 individuals reporting persistent pain in the anatomical area of surgery, 51.0% reported chronic pain when questioned without specific reference to the surgery.

The present study supports evidence from clinical studies of persistent postsurgical pain, indicating a high prevalence, but reveals large discrepancies in report of pain, depending on the questions asked and the context in which the questions are presented.

Strong associations between sensory abnormalities and pain indicate neuropathic mechanisms in a major proportion of cases.

[MeSH-major] Chronic Pain / epidemiology. Pain, Postoperative / epidemiology

[MeSH-minor] Adult. Aged. Cross-Sectional Studies. Female. Humans. Male. Middle Aged. Norway / epidemiology. Pain Measurement. Prevalence. Questionnaires. Risk Factors

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[Copyright] Copyright © 2012 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

[CommentIn] Pain. 2012 Jul;153(7):1344-5 [22424875.001]

(PMID = 22445291.001).

[ISSN] 1872-6623

[Journal-full-title] Pain

[ISO-abbreviation] Pain

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Netherlands

   

36. |......... 4%  Bozynski CC, Vasquez L, O'Brien DP, Johnson GC: Compressive myelopathy associated with ectasia of the vertebral and spinal arteries in a dog. Vet Pathol; 2012 Sep;49(5):779-83

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A 4-year-old dog was presented for acute, progressive tetraparesis and cervical hyperesthesia.

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(PMID = 21856870.001).

[ISSN] 1544-2217

[Journal-full-title] Veterinary pathology

[ISO-abbreviation] Vet. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

   

37. |......... 4%  Cruz-Arámbulo R, Nykamp S: Acute intraparenchymal spinal cord injury in a cat due to high-rise syndrome. Can Vet J; 2012 Mar;53(3):274-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The cat had paraplegia of the hind limbs, intact reflexes and pain perception, and hyperesthesia in the caudal thoracic area.

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[Cites] Eur Spine J. 2010 Mar;19 Suppl 1:S8-17 [19727855.001]

[Cites] J Vet Intern Med. 2009 Nov-Dec;23(6):1220-6 [19780928.001]

[Cites] J Small Anim Pract. 2004 Jun;45(6):284-8 [15206472.001]

[Cites] J Feline Med Surg. 2004 Oct;6(5):305-12 [15363762.001]

[Cites] Neurosurgery. 2004 Dec;55(6):1325-42; discussion 1342-3 [15574214.001]

[Cites] J Feline Med Surg. 2005 Apr;7(2):101-7 [15771946.001]

[Cites] J Vet Dent. 2006 Mar;23(1):50-60 [16718994.001]

[Cites] Vet Rec. 2007 Jun 9;160(23):795-9 [17558027.001]

[Cites] Spine J. 2009 Mar;9(3):e5-8 [18495542.001]

[Cites] J Feline Med Surg. 2009 Feb;11(2):53-9 [18602328.001]

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(PMID = 22942443.001).

[ISSN] 0008-5286

[Journal-full-title] The Canadian veterinary journal. La revue vétérinaire canadienne

[ISO-abbreviation] Can. Vet. J.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Canada

[Other-IDs] NLM/ PMC3280780

   

38. |......... 4%  Ozkan BT, Celik S, Durmus E: Paresthesia of the mental nerve stem from periapical infection of mandibular canine tooth: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 May;105(5):e28-31

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Sensory disturbances such as paresthesia, anesthesia, hypoesthesia, and hyperesthesia may be present in the oral cavity.

Paresthesia is defined as a burning or prickling sensation or partial numbness caused by neural injury.

The main purpose of this case report is to present the treatment and resolution of a mental nerve paresthesia stemming from apical pathosis of a mandibular canine tooth and the follow-up of 3 years.

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(PMID = 18442732.001).

[ISSN] 1528-395X

[Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics

[ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Anti-Inflammatory Agents, Non-Steroidal

   

39. |......... 4%  Thibaud JL, Hidalgo A, Benchekroun G, Fanchon L, Crespeau F, Delisle F, Blot S: Progressive myelopathy due to a spontaneous intramedullary hematoma in a dog: pre- and postoperative clinical and magnetic resonance imaging follow-up. J Am Anim Hosp Assoc; 2008 Sep-Oct;44(5):266-75

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Progressive myelopathy due to a spontaneous intramedullary hematoma in a dog: pre- and postoperative clinical and magnetic resonance imaging follow-up.

A 4-year-old, male Jack Russell terrier was presented for a 6-month history of progressive right hemiparesis with episodic cervical hyperesthesia.

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(PMID = 18762564.001).

[ISSN] 1547-3317

[Journal-full-title] Journal of the American Animal Hospital Association

[ISO-abbreviation] J Am Anim Hosp Assoc

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

40. |......... 4%  Levine JM, Scrivani PV, Divers TJ, Furr M, Mayhew IJ, Reed S, Levine GJ, Foreman JH, Boudreau C, Credille BC, Tennent-Brown B, Cohen ND: Multicenter case-control study of signalment, diagnostic features, and outcome associated with cervical vertebral malformation-malarticulation in horses. J Am Vet Med Assoc; 2010 Oct 1;237(7):812-22

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Gait asymmetry and cervical hyperesthesia were frequently detected in horses with CVM.

CONCLUSIONS AND CLINICAL RELEVANCE: Odds of a diagnosis of CVM were greater in young horses and horses of specific breeds.

Detection of gait asymmetry and cervical hyperesthesia were frequently reported in association with CVM.

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(PMID = 20919847.001).

[ISSN] 0003-1488

[Journal-full-title] Journal of the American Veterinary Medical Association

[ISO-abbreviation] J. Am. Vet. Med. Assoc.

[Language] eng

[Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

[Publication-country] United States

   

41. |......... 4%  Kitamura Y, Sakakura N, Uchida T, Suyama M: [Neurinoma arising from brachial plexus with intrathoracic extension resected through the second intercostal space]. Kyobu Geka; 2010 Dec;63(13):1133-5

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The tumor was resected through the 2nd intercostal space under an axillary skin incision approach and diagnosed as neurinoma on histological examination.

He had a complaint of hyperesthesia of the right upper arm for 2 months postoperatively.

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(PMID = 21174662.001).

[ISSN] 0021-5252

[Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery

[ISO-abbreviation] Kyobu Geka

[Language] jpn

[Publication-type] Case Reports; English Abstract; Journal Article

[Publication-country] Japan

   

42. |......... 4%  Schneider AR, Chen AV, Tucker RL: Imaging diagnosis--Vertebral canal porcupine quill with presumptive secondary arachnoid diverticulum. Vet Radiol Ultrasound; 2010 Mar-Apr;51(2):152-4

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

A 3-year-old Gordon Setter developed cervical hyperesthesia and a stiff gait.

At a retrospective review of the MR images, the quill appeared as a circular well-demarcated T2-hypointense lesion.

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(PMID = 20402400.001).

[ISSN] 1058-8183

[Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

[ISO-abbreviation] Vet Radiol Ultrasound

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

   

43. |......... 4%  Maddaford S, Renton P, Speed J, Annedi SC, Ramnauth J, Rakhit S, Andrews J, Mladenova G, Majuta L, Porreca F: 1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors. Bioorg Med Chem Lett; 2011 Sep 15;21(18):5234-8

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

In general compounds with bulkier side chains displayed increased selectivity for nNOS over eNOS and iNOS isoforms.

One of the compounds, (R)-8 was shown to reduce tactile hyperesthesia (allodynia) after oral administration (30 mg/kg) in an in vivo rat model of dural inflammation relevant to migraine pain.

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[Copyright] Copyright © 2011 Elsevier Ltd. All rights reserved.

(PMID = 21824773.001).

[ISSN] 1464-3405

[Journal-full-title] Bioorganic & medicinal chemistry letters

[ISO-abbreviation] Bioorg. Med. Chem. Lett.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] England

[Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Indoles; EC 1.14.13.39 / Nitric Oxide Synthase

   

44. |......... 4%  Hanai S, Komaki H, Sakuma H, Nakagawa E, Sugai K, Sasaki M, Oya Y, Higurashi N, Hamano S: Acute autonomic sensory and motor neuropathy associated with parvovirus B19 infection. Brain Dev; 2011 Feb;33(2):161-5

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The patient presented with fever, erythema of the entire body, and abdominal pain with vomiting.

Symptoms such as muscle weakness, severe hyperesthesia, dyshidrosis, and neurogenic bladder associated with autonomic disturbance developed over several days.

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[Copyright] Copyright © 2010 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

(PMID = 20395090.001).

[ISSN] 1872-7131

[Journal-full-title] Brain & development

[ISO-abbreviation] Brain Dev.

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] Netherlands

[Chemical-registry-number] 0 / Antibodies, Viral

   

45. |......... 3%  Gustorff B, Sycha T, Lieba-Samal D, Rolke R, Treede RD, Magerl W: The pattern and time course of somatosensory changes in the human UVB sunburn model reveal the presence of peripheral and central sensitization. Pain; 2013 Apr;154(4):586-97

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

Primary hyperalgesia in UVB-irradiated skin and secondary hyperalgesia in adjacent nonirradiated skin were studied in 22 healthy subjects 24h after irradiation with UVB at 3-fold minimal erythema dose of a skin area 5 cm in diameter at the thigh and compared to mirror-image contralateral control areas.

Within the sunburn area, cold hyperesthesia (P=.01), profound generalized hyperalgesia to heat (P<.001), cold (P<.05), pinprick and pressure (P<.001), and mild dynamic mechanical allodynia (P<.001) were present.

The finding of cold hyperalgesia and cold hyperesthesia is new in this model.

These data reveal that the UVB sunburn model activates a broad spectrum of peripheral and central sensitization mechanisms and hence is a useful human surrogate model to be used as a screening tool for target engagement in phases 1 and 2a of drug development.

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[Copyright] Copyright © 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

(PMID = 23419598.001).

[ISSN] 1872-6623

[Journal-full-title] Pain

[ISO-abbreviation] Pain

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Netherlands

   

46. |......... 3%  Cvijanović M, Ilin M, Slankamenac P, Horvat SB, Jovin Z: The sensitivity of electromyoneurography in the diagnosis of diabetic polyneuropathy. Med Pregl; 2011 Jan-Feb;64(1-2):11-4

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] The sensitivity of electromyoneurography in the diagnosis of diabetic polyneuropathy.

Its symptoms are paresthesia, dysesthesia and pain.

The signs of damage to the peripheral neurons are hypoesthesia, hypoalgesia, hyperesthesia and hyperalgesia, decreased tendon reflexes, and, possibly, weakness and muscle atrophy.

One hundred patients with diabetes mellitus were examined in order to investigate the sensitivity of different electromyographic parameters.

[MeSH-minor] Humans. Sensitivity and Specificity

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(PMID = 21545063.001).

[ISSN] 0025-8105

[Journal-full-title] Medicinski pregled

[ISO-abbreviation] Med. Pregl.

[Language] eng

[Publication-type] Journal Article

[Publication-country] Serbia

   

47. |......... 3%  Heij L, Dahan A, Hoitsma E: Sarcoidosis and pain caused by small-fiber neuropathy. Pain Res Treat; 2012;2012:256024

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

[Title] Sarcoidosis and pain caused by small-fiber neuropathy.

Sarcoidosis is a chronic inflammatory illness and small-fiber neuropathy (SFN) is one of the disabling and often chronic manifestations of the disease.

SFN presents with peripheral pain and symptoms of autonomic dysfunction.

The character of the pain can be burning or shooting.

Besides, allodynia and hyperesthesia can exist.

The aim of treatment is often to reduce pain; however, total pain relieve is seldom achieved.

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(PMID = 23304492.001).

[ISSN] 2090-1550

[Journal-full-title] Pain research and treatment

[ISO-abbreviation] Pain Res Treat

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Other-IDs] NLM/ PMC3523152

   

48. |......... 3%  Bornstein J, Cohen Y, Zarfati D, Sela S, Ophir E: Involvement of heparanase in the pathogenesis of localized vulvodynia. Int J Gynecol Pathol; 2008 Jan;27(1):136-41

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

The hyperinnervation has been thought to cause the vestibular hyperesthesia distinctive of localized vulvodynia.

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(PMID = 18156988.001).

[ISSN] 0277-1691

[Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

[ISO-abbreviation] Int. J. Gynecol. Pathol.

[Language] eng

[Publication-type] Journal Article

[Publication-country] United States

[Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 3.2.1.- / heparanase; EC 3.2.1.31 / Glucuronidase

   

49. |......... 3%  Matsumoto-Miyai K, Yamada E, Yoshizumi M, Kawatani M: The regulation of distention-induced ATP release from urothelium by the adenylyl cyclase-cyclic AMP pathway. Biomed Res; 2012 Jun;33(3):153-7

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

An excess of urothelial ATP release was found in interstitial cystitis, a condition accompanied by hyperesthesia of the urinary bladder; it remains unclear which signals are involved in this upregulation.

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(PMID = 22790214.001).

[ISSN] 1880-313X

[Journal-full-title] Biomedical research (Tokyo, Japan)

[ISO-abbreviation] Biomed. Res.

[Language] eng

[Publication-type] Journal Article; Research Support, Non-U.S. Gov't

[Publication-country] Japan

[Chemical-registry-number] 0 / Enzyme Inhibitors; 56-65-5 / Adenosine Triphosphate; 60-92-4 / Cyclic AMP; EC 4.6.1.1 / Adenylate Cyclase

   

50. |......... 3%  Devere R: Guillain-Barré syndrome after a jellyfish sting. J Clin Neuromuscul Dis; 2011 Jun;12(4):227-30

[Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.

This is the case of a jellyfish sting associated with the rare development of Guillain-Barré syndrome.

Ten days later, she developed low back and right thigh pain followed by progressive numbness and weakness in all extremities.

Initial neurologic examination showed areflexia, weakness, absent vibration and position sense, and hyperesthesia to pin and light touch in the mid to distal region of all four extremities.

The only treatment was gabapentin for neuropathy pain.

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(PMID = 22361521.001).

[ISSN] 1537-1611

[Journal-full-title] Journal of clinical neuromuscular disease

[ISO-abbreviation] J Clin Neuromuscul Dis

[Language] eng

[Publication-type] Case Reports; Journal Article

[Publication-country] United States

[Chemical-registry-number] 0 / Cnidarian Venoms

   

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