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1. Biomedical articles (top 16; 2009 to 2014)
1. |||||..... 50%  Agarwal R, Khan A, Aggarwal AN, Gupta D: Bronchoscopic lung biopsy using noninvasive ventilatory support: case series and review of literature of NIV-assisted bronchoscopy. Respir Care; 2012 Nov;57(11):1927-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bronchoscopic lung biopsy using noninvasive ventilatory support: case series and review of literature of NIV-assisted bronchoscopy.
  • BACKGROUND: Fiberoptic bronchoscopy and lung biopsy are important diagnostic tools in patients with diffuse pulmonary infiltrates.
  • However, these patients often have hypoxemic respiratory failure that makes this procedure hazardous.
  • OBJECTIVE: To report the efficacy and safety of an innovative technique of NIV-assisted bronchoscopic lung biopsy in a small case-series of hypoxemic subjects with diffuse parenchymal infiltrates; also to systematically review the literature on NIV-assisted bronchoscopy.
  • METHODS: Subjects with bilateral diffuse parenchymal infiltrates and P(aO(2))/F(IO(2)) < 200 mm Hg underwent bronchoscopic lung biopsy under NIV support.
  • NIV was initiated 10 min before the procedure and continued for 30 min after the procedure.
  • The primary outcomes were performance of successful procedure and episodes of decline in S(pO(2)) < 90%.
  • Secondary end points were the change in the respiratory and hemodynamic parameters during the procedure and occurrence of complications such as pneumothorax, hemorrhage, and endotracheal intubation.
  • The median (interquartile range [IQR]) P(aO(2))/F(IO(2)) prior to lung biopsy was 164.5 mm Hg (146.3-176.3 mm Hg), and the median (IQR) inspiratory and expiratory positive airway pressures were 14 cm H(2)O (12-15 cm H(2)O) and 5 cm H(2)O.
  • Fiberoptic bronchoscopy was well tolerated and all subjects maintained S(pO(2)) > 92% during the procedure.
  • A repeat procedure was performed in one subject, which again yielded no diagnosis.
  • CONCLUSIONS: NIV-assisted bronchoscopic lung biopsy is a novel method for obtaining diagnosis in hypoxemic patients with diffuse lung infiltrates.
  • [MeSH-major] Biopsy / methods. Bronchoscopy / methods. Lung Diseases / diagnosis. Noninvasive Ventilation

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  • (PMID = 22417703.001).
  • [ISSN] 0020-1324
  • [Journal-full-title] Respiratory care
  • [ISO-abbreviation] Respir Care
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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2. ||||...... 37%  Firoozbakhsh S, Seifirad S, Safavi E, Dinparast R, Taslimi S, Derakhshandeilami G: [Comparison of hot versus cold biopsy forceps in the diagnosis of endobronchial lesions]. Arch Bronconeumol; 2011 Nov;47(11):547-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Comparison of hot versus cold biopsy forceps in the diagnosis of endobronchial lesions].
  • [Transliterated title] Comparación de las pinzas de biopsia caliente frente a fría en el diagnóstico de lesiones endobronquiales.
  • INTRODUCTION: Traditionally cold biopsy forceps were used for endobronchial biopsy, and recently electrocautery (hot) bronchoscopy biopsy forceps are introduced.
  • It is hypothesized that hot biopsy forceps may decrease procedure related bleeding and also may decrease the quality of obtained samples.
  • PATIENTS AND METHODS: Patients with different indications for endobronchial biopsy during fiberoptic bronchoscopy underwent three hot and three cold biopsies with a random fashion.
  • All biopsies were obtained with a single biopsy forceps with and without the application of an electrocoagulation current, set on soft coagulation mode (40W).
  • The average bleeding score following hot biopsy was significantly lower compared to the cold biopsy (P=.006).
  • There was no significant difference between the diagnostic yields of two biopsy methods (P=.687).
  • CONCLUSIONS: Hot biopsy forceps significantly decreased the procedure related bleeding.
  • Regarding low prevalence of bleeding following endobronchial biopsy, routine use of hot bronchoscopy forceps is not reasonable.
  • However, familiarity of bronchoscopists with this method may improve bronchoscopy safety.
  • [MeSH-major] Biopsy / instrumentation. Bronchi / pathology. Bronchoscopy. Cold Temperature. Electrocoagulation / instrumentation. Hot Temperature
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Bronchial Diseases / diagnosis. Bronchial Diseases / pathology. Female. Fiber Optic Technology. Hemorrhage / epidemiology. Hemorrhage / etiology. Hemorrhage / prevention & control. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Male. Middle Aged. Prevalence. Prospective Studies. Single-Blind Method. Surgical Instruments

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  • [Copyright] Copyright © 2011 SEPAR. Published by Elsevier Espana. All rights reserved.
  • (PMID = 22036191.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] Spain
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3. ||||...... 37%  Funakoshi Y, Sawabata N, Takeuchi Y, Kusumoto H, Kimura T, Maeda H: Clinical implication of pulmonary excision for undiagnosed peripheral lung cancer. Interact Cardiovasc Thorac Surg; 2011 Nov;13(5):485-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical implication of pulmonary excision for undiagnosed peripheral lung cancer.
  • Surgical excision is an option to diagnose small-sized lung cancer, although this procedure has potential to disseminate tumor cells from the surgical margin.
  • This retrospective study enrolled 252 patients with clinical stage IA non-small cell lung carcinoma who had undergone lobectomy during the period 1998-2004.
  • Except for 25 patients with ground-glass attenuation (GGA) lesions on computed tomography, all underwent preoperative biopsy using flexible fiberoptic bronchoscopy (FFB).
  • A total of 148 patients were diagnosed by FFB, and 86 were diagnosed by surgical excision.
  • In the surgical excision cases, 67 tumors were negative for malignancy at the surgical margins and 19 were positive.
  • Diagnosis by surgical excision was associated significantly more often with smaller tumor size (P<0.0001), a greater number of GGA lesions (P=0.0006) and a lower pathological stage (P=0.001) than those diagnosed by FFB.
  • In the groups that underwent excision, there was no significant difference in survival between those with positive and negative cytological margins.
  • The survival of patients diagnosed by surgical excision was significantly better than that of those diagnosed by FFB in clinical stage IA disease.
  • Surgical excision is an optimal method to diagnose small lung cancer because the malignant status of the margin does not appear to influence the outcome.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnosis. Carcinoma, Non-Small-Cell Lung / surgery. Lung Neoplasms / diagnosis. Lung Neoplasms / surgery. Pneumonectomy
  • [MeSH-minor] Aged. Biopsy. Bronchoscopy. Chi-Square Distribution. Female. Fiber Optic Technology. Humans. Japan. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Seeding. Neoplasm Staging. Predictive Value of Tests. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 21835845.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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4. ||||...... 37%  Bruno P, Ricci A, Esposito MC, Scozzi D, Tabbì L, Sposato B, Falasca C, Giarnieri E, Giovagnoli MR, Mariotta S: Efficacy and cost effectiveness of rapid on site examination (ROSE) in management of patients with mediastinal lymphadenopathies. Eur Rev Med Pharmacol Sci; 2013 Jun;17(11):1517-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The diagnostic and staging approach for the mediastinal lymphadenopathies, with or whithout pulmonary lesions endoscopically visible, is based on transbronchial needle aspiration (TBNA) during fiberoptic bronchoscopy and on mediastinoscopy.
  • PATIENTS AND METHODS: 120 patients, affected by mediastinal lymphadenopathies suspected for lung cancer, underwent TBNA during fiberoptic bronchoscopy: 60 patients without ROSE (group A) and other 60 with ROSE (group B).
  • With regards to the costs of the procedures performed in the diagnostic process, the use of TBNA with ROSE as first diagnostic approach has saved a considerable amount of euros (19,413) compared to the use of TBNA without ROSE and the combined procedure increased (p < 0.02; chi square test) the sensitivity of TBNA by 15%.
  • CONCLUSIONS: ROSE significantly impacts on the diagnostic yield, as well as on the overall management costs of patients with mediastinal lymphadenopathy, suspected for lung cancer.
  • [MeSH-minor] Aged. Biopsy, Needle / economics. Bronchoscopy / economics. Cost-Benefit Analysis. Female. Humans. Male. Mediastinoscopy / economics. Middle Aged

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  • (PMID = 23771540.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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5. ||||...... 36%  Zhong CX, Yao F, Zhao H, Shi JX, Fan LM: Long-term outcomes of surgical treatment for pulmonary carcinoid tumors: 20 years' experience with 131 patients. Chin Med J (Engl); 2012 Sep;125(17):3022-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Preoperative fiberoptic bronchoscopy was performed in all patients.
  • Endoscopic biopsy was performed in 100 patients with central tumors, and 70 (70%) patients were diagnosed as bronchial carcinoid.
  • The resections performed consisted of 31 pneumonectomie, 32 lobectomies, 26 bilobectomies, 34 sleeve lobectomies, six bronchoplastic procedures without lung resection, and two segmentectomies.
  • The 3-, 5- and 10-year overall survival rates of pneumonectom and bronchoplastic surgery (including sleeve lobectomy and bronchoplastic procedure without lung resection) were 93.2%, 81.0% and 69.4%, 97.5%, 91.9% and 70.0%, respectively.
  • [MeSH-major] Carcinoid Tumor / surgery. Lung Neoplasms / surgery

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  • (PMID = 22932173.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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6. |||....... 28%  Bodh A, Kaushal V, Kashyap S, Gulati A: Cytohistological correlation in diagnosis of lung tumors by using fiberoptic bronchoscopy: study of 200 cases. Indian J Pathol Microbiol; 2013 Apr-Jun;56(2):84-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytohistological correlation in diagnosis of lung tumors by using fiberoptic bronchoscopy: study of 200 cases.
  • BACKGROUND: Examination of specimens obtained through flexible fiberoptic bronchoscope is an important and often the initial diagnostic technique performed in patients with suspected malignant lung lesion.
  • AIMS: To evaluate the correlation of cytological findings of bronchial washings, bronchial brushing and imprint smear of bronchial biopsy in the diagnosis of lung tumors, with histopathology of bronchial biopsy taking the latter as the confirmatory diagnostic test.
  • MATERIALS AND METHODS: A total of 200 patients with lung mass were included in the study.
  • In the first 100 cases, pre-biopsy bronchial washing (washing collected before the brushing and biopsy procedure) while post-biopsy washing (washing at the end of the procedure) was procured in all 200 cases.
  • Imprint smears of bronchial biopsy were prepared in 150 cases.
  • Pre-biopsy and post-biopsy washing showed high specificity of 88.89%, but low sensitivity of 30.14 and 36.77% respectively.
  • No significant difference was found in sensitivity between brushing and imprint smear (Chi-square; P = 0.4187); and between pre-biopsy and post-biopsy washing (Chi-square; P = 0.7982).
  • CONCLUSION: Bronchial brushing and washing cytology in combination with imprint cytology aids in the diagnosis of lung tumors.
  • Therefore, all these techniques may be used concurrently along with bronchial biopsy to diagnose lung tumors.

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  • (PMID = 24056640.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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8. ||||...... 36%  Wang YC, Huang ZG, Shi J, Zhang XZ: [Diagnostic value of computed tomography in invasive pulmonary fungal infections]. Zhonghua Yi Xue Za Zhi; 2011 Jan 4;91(1):20-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To analyze the computed tomographic (CT) features of invasive pulmonary fungal infections (IPFI) and evaluate the value of CT-guided percutaneous biopsy.
  • METHODS: Seventeen IPFI cases diagnosed by CT-guided percutaneous biopsy were recruited.
  • (1) Candida albicans (n = 7) and cryptococcosis & aspergillus (n = 5) were identified. (2) It showed segmental on lobar consolidation within lung field (n = 6), mixture of patterns and nodule (n = 4) and mass (n = 7). (3) The overall diagnostic accuracy of fiberoptic bronchoscopy examination was 35.3%. (4) The incidence of complicated pneumothorax was 11.8% (2/17).
  • And the CT-guided percutaneous is a safe and effective procedure.
  • [MeSH-major] Biopsy, Needle / methods. Lung Diseases, Fungal / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 21418956.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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2. Definitions


3. Related RMF webpages
1. fiberoptic bronchoscopy with biopsy of lung procedure
2. open biopsy of lung procedure
3. percutaneous needle biopsy lung procedure
4. bbx bronchoscopy and biopsy
5. flexible fiberoptic sigmoidoscopy procedure
6. bronchoscopy with removal of foreign body procedure
7. transbronchial lung biopsy
8. lung needle biopsy
9. closed biopsy of lung
10. biopsy of lung nos
11. thoracoscopic biopsy of lung nos
12. lung pleura biopsy or of
13. laryngoscopy fiberoptic
14. biopsy of rectum procedure
15. biopsy of mouth procedure
16. biopsy of vulva procedure
17. biopsy of omentum procedure
18. biopsy of peritoneum procedure
19. biopsy of nose procedure
20. biopsy of ovary procedure
21. endocervical biopsy procedure
22. biopsy of diaphragm procedure
23. biopsy of anus procedure
24. vaginal biopsy procedure
25. conjunctival biopsy procedure
26. biopsy of tongue procedure
27. biopsy of penis procedure
28. biopsy of pleura procedure
29. pericardial biopsy procedure
30. biopsy of urethra procedure
31. biopsy of thyroid procedure
32. biopsy of femur procedure
33. biopsy of small intestine procedure
34. biopsy of lesion of spleen procedure
35. biopsy of large intestine procedure
36. open biopsy of kidney procedure
37. biopsy of parathyroid gland procedure
38. transrectal biopsy of prostate procedure
39. biopsy of breast nos procedure
40. thoracoscopic biopsy of pleura procedure
41. transurethral biopsy prostate procedure
42. stereotactic biopsy of brain procedure
43. biopsy of seminal vesicle procedure
44. needle biopsy of liver procedure
45. transjugular biopsy of liver procedure
46. wedge biopsy of liver procedure
47. biopsy of adrenal gland procedure
48. open biopsy of liver procedure
49. needle biopsy of kidney procedure
50. biopsy of temporal artery procedure

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