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1. Biomedical articles (top 50; 2009 to 2014)
1. |||||..... 50%  Benarroch EE: Postural tachycardia syndrome: a heterogeneous and multifactorial disorder. Mayo Clin Proc; 2012 Dec;87(12):1214-25
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  • [Title] Postural tachycardia syndrome: a heterogeneous and multifactorial disorder.
  • POTS is frequently included in the differential diagnosis of chronic unexplained symptoms, such as inappropriate sinus tachycardia, chronic fatigue, chronic dizziness, or unexplained spells in otherwise healthy young individuals.
  • Many patients with POTS also report symptoms not attributable to orthostatic intolerance, including those of functional gastrointestinal or bladder disorders, chronic headache, fibromyalgia, and sleep disturbances.
  • [MeSH-major] Postural Orthostatic Tachycardia Syndrome / diagnosis. Postural Orthostatic Tachycardia Syndrome / therapy

  • HSDB. structure - Norepinephrine.
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  • [Copyright] Copyright © 2012 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
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  • (PMID = 23122672.001).
  • [ISSN] 1942-5546
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sodium, Dietary; 059QF0KO0R / Water; X4W3ENH1CV / Norepinephrine
  • [Other-IDs] NLM/ PMC3547546
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2. |||||..... 49%  Klingele CJ, Lightner DJ, Fletcher JG, Gebhart JB, Bharucha AE: Dysfunctional urinary voiding in women with functional defecatory disorders. Neurogastroenterol Motil; 2010 Oct;22(10):1094-e284
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dysfunctional urinary voiding in women with functional defecatory disorders.
  • BACKGROUND: While pelvic floor dysfunction may manifest with bladder or bowel symptoms, the relationship between functional defecatory disorders and dysfunctional voiding is unclear.
  • Our hypothesis was that patients with defecatory disorders have generalized pelvic floor dysfunction, manifesting as dysfunctional urinary voiding.
  • METHODS: Voiding was assessed by a symptom questionnaire, a voiding diary, uroflowmetry, and by measuring the postvoid residual urine volume in this case-control study of 28 patients with a functional defecatory disorder (36 ± 2 years, mean ± SEM) and 30 healthy women (36 ± 2 years).
  • KEY RESULTS:  Women with a defecatory disorder frequently reported urinary symptoms: urgency (61%), frequency (36%), straining to begin (21%), or finish (50%) voiding, and the sense of incomplete emptying (54%).
  • Fluid intake and output, the minimum voided volume, and the shortest duration between voids measured by voiding diaries were higher (P < 0.05) in patients than in controls.
  • The risk of abnormal voiding by uroflowmetry was higher in patients (OR 8.0; 95% CI, 2.3-26.9) than in controls.
  • Patients took longer than controls (P < 0.01) to attain the maximum urinary flow rate (12 ± 2 VS 4 ± 0 s) and to empty the bladder (29 ± 4 VS 20 ± 2 s), but the maximum urinary flow rate and postvoid residual volumes were not significantly different.
  • CONCLUSIONS & INFERENCES: Symptoms of dysfunctional voiding and uroflowmetric abnormalities occurred more frequently, suggesting of disordered urination, in women with a defecatory disorder than in healthy controls.

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  • (PMID = 20557469.001).
  • [ISSN] 1365-2982
  • [Journal-full-title] Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • [ISO-abbreviation] Neurogastroenterol. Motil.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK 78924; United States / NIDDK NIH HHS / DK / R01 DK078924
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS214407; NLM/ PMC2939914
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3. |||||..... 48%  Kim SE, Chang L: Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms? Neurogastroenterol Motil; 2012 Oct;24(10):895-913
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  • [Title] Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms?
  • BACKGROUND: Irritable bowel syndrome and other gastrointestinal (GI) and non-GI disorders such as functional dyspepsia, fibromyalgia, temporomandibular joint disorder, interstitial cystitis/painful bladder syndrome, and chronic fatigue syndrome are known as functional pain syndromes.
  • Studies suggest that these functional disorders are multifactorial, but factors which increase the vulnerability of developing these conditions are shared.

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  • [Copyright] © 2012 Blackwell Publishing Ltd.
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  • (PMID = 22863120.001).
  • [ISSN] 1365-2982
  • [Journal-full-title] Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • [ISO-abbreviation] Neurogastroenterol. Motil.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / P50 DK064539; United States / NIDDK NIH HHS / DK / P50 DK64539; United States / NIAMS NIH HHS / AR / R01 AR046122; United States / NIAMS NIH HHS / AR / R01 AR46122
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS522332; NLM/ PMC3812246
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4. |||||..... 46%  Leiria LO, Sollon C, Calixto MC, Lintomen L, Mónica FZ, Anhê GF, De Nucci G, Zanesco A, Grant AD, Antunes E: Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. PLoS One; 2012;7(11):e48507
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Obesity/metabolic syndrome are common risk factors for overactive bladder.
  • This study aimed to investigate the functional and molecular changes of detrusor smooth muscle (DSM) in high-fat insulin resistant obese mice, focusing on the role of protein kinase C (PKC) and Ca(v)1.2 in causing bladder dysfunction.
  • In vitro functional responses and cystometry, as well as PKC and Ca(v)1.2 expression in bladder were evaluated.
  • Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice.
  • PKC protein expression was markedly higher in bladder tissues from obese mice, which was normalized by metformin treatment.
  • Our findings show that Ca(v)1.2 blockade and improvement of insulin sensitization restores the enhanced PKC protein expression in bladder tissues and normalizes the overactive detrusor.
  • It is likely that insulin resistance importantly contributes for the pathophysiology of this urological disorder in obese mice.
  • [MeSH-major] Calcium Channels, L-Type / metabolism. Insulin Resistance. Obesity / complications. Obesity / physiopathology. Protein Kinase C / metabolism. Urinary Bladder, Overactive / complications. Urinary Bladder, Overactive / physiopathology

  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Overactive Bladder.
  • HSDB. structure - CALCIUM CHLORIDE.
  • HSDB. structure - AMLODIPINE BESYLATE.
  • HSDB. structure - METFORMIN HYDROCHLORIDE.
  • HSDB. structure - CARBACHOL CHLORIDE.
  • HSDB. structure - POTASSIUM CHLORIDE.
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  • (PMID = 23144896.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / BB/E527098/1
  • [Publication-type] In Vitro; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium Channel Blockers; 0 / Calcium Channels, L-Type; 0 / Cav1.2 protein, mouse; 0 / Insulin; 1J444QC288 / Amlodipine; 37558-16-0 / Phorbol 12,13-Dibutyrate; 51-83-2 / Carbachol; 660YQ98I10 / Potassium Chloride; 9100L32L2N / Metformin; EC 2.7.11.13 / Protein Kinase C; M4I0D6VV5M / Calcium Chloride
  • [Other-IDs] NLM/ PMC3492456
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5. |||||..... 52%  Costantini E, Lazzeri M, Bini V, Zucchi A, Fioretti F, Frumenzio E, Porena M: Open-label, longitudinal study of tamsulosin for functional bladder outlet obstruction in women. Urol Int; 2009;83(3):311-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Open-label, longitudinal study of tamsulosin for functional bladder outlet obstruction in women.
  • OBJECTIVES: To investigate the clinical effect of tamsulosin for the treatment of functional bladder outlet obstruction (BOO) in adult women.
  • METHODS: In a prospective, longitudinal open-label study, 63 women affected by functional BOO were treated with tamsulosin.
  • Inclusion criteria were: age >18 years, reporting voiding symptoms (intermittent stream, hesitancy, straining and/or a feeling of incomplete emptying), uroflowmetry maximum flow rate (Q(max)) under 12 ml and/or presence of postvoid residual greater than 50% of the voiding volume.
  • Exclusion criteria were: patients suffering from any other anatomical or functional disorder such as urethral stenosis, pelvic organ prolapse, neurological disturbances, or systemic diseases that could impact upon bladder voiding.
  • Voiding and storage symptoms and uroflowmetry results were assessed before and at the end of the alpha-blocker therapy.
  • After therapy voiding symptoms improved in 71.4% of patients (45/63; p < 0.0001), and if associated with storage symptoms in 66.67% (26/39; p < 0.00001).
  • An improvement was observed in 66% (16/24) of patients with isolated voiding symptoms, in 51.2% (20/39) with associated storage symptoms and in 65% (17/26) of women with associated recurrent urinary infections.
  • CONCLUSIONS: These results suggest that alpha-blocker may be an effective treatment option in women with voiding dysfunction due to functional BOO.
  • [MeSH-major] Adrenergic alpha-Antagonists / therapeutic use. Sulfonamides / therapeutic use. Urinary Bladder Neck Obstruction / drug therapy

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  • (PMID = 19829032.001).
  • [ISSN] 1423-0399
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Adrenergic alpha-Antagonists; 0 / Sulfonamides; G3P28OML5I / tamsulosin
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6. |||....... 32%  Cooper IF, Siadaty MS: 'Functional Concepts' associated with 'Bladder Disorder Neurogenic': Top Publications. BioMedLib Review; FunctionalConcept;BladderDisorderNeurogenic:706187388. ISSN: 2331-5717. 2014/2/24
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  • [Title] 'Functional Concepts' associated with 'Bladder Disorder Neurogenic': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Functional Concept' for 'bladder disorder neurogenic'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Functional Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 25 publications, and group two 1491 publications.
  • Here are the top 10.
  • Ruffion A et al: Systematic review of the epidemiology of urinary incontinence and detrusor overactivity among patients with neurogenic overactive bladder.
  • Balsara ZR et al: Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder.
  • Chen M et al: Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle.
  • Huynh D et al: Use of intravesicular amikacin irrigations for the treatment and prophylaxis of urinary tract infections in a patient with spina bifida and neurogenic bladder: a case report.
  • Ivancić V et al: Progression of renal insufficiency in children and adolescents with neuropathic bladder is not accelerated by lower urinary tract reconstruction.
  • Heyns CF: Urinary tract infection associated with conditions causing urinary tract obstruction and stasis, excluding urolithiasis and neuropathic bladder.
  • Thyoka M et al: Two siblings with unbalanced t(10;21) translocations and non-neuropathic neuropathic bladder.
  • Fox JA et al: Cystatin C as a marker of early renal insufficiency in children with congenital neuropathic bladder.
  • Rhee AC et al: Percutaneous cystolithotomy in the pediatric neuropathic bladder with laparoscopic trocar access: a modified approach useful for the augmented and native bladder, and continent urinary reservoir.
  • Horst M et al: Repeated Botulinum-A toxin injection in the treatment of neuropathic bladder dysfunction and poor bladder compliance in children with myelomeningocele.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706187388.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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7. |||||..... 52%  Ren JN: [Theoretical and clinical application of insomnia caused by "stomach disorder could lead to excess of yang-qiao meridian"]. Zhongguo Zhen Jiu; 2013 Feb;33(2):168-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Theoretical and clinical application of insomnia caused by "stomach disorder could lead to excess of yang-qiao meridian"].
  • To explore the mechanism of insomnia caused by "stomach disorder could lead to excess of yang-qiao meridian" and clinical application of treating insomnia with acupoints in qiao meridian as the main points.
  • Qiao meridian for sleep is mainly because it is connected with eyes through the Bladder Meridian of Foot-Taiyang.
  • For Stomach Meridian of Foot-Yangming is intersected with the Bladder Meridian of Foot-Taiyang in Jingming (BL 1), and intersected with yin and yang qiao meridian beside the mouth and under the eye, once functional disorder of the stomach, it can affect qi movements of the whole body and give rise to various pathological changes that cause insomnia.

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  • (PMID = 23620952.001).
  • [ISSN] 0255-2930
  • [Journal-full-title] Zhongguo zhen jiu = Chinese acupuncture & moxibustion
  • [ISO-abbreviation] Zhongguo Zhen Jiu
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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8. |||||..... 46%  Chelimsky G, Heller E, Buffington CA, Rackley R, Zhang D, Chelimsky T: Co-morbidities of interstitial cystitis. Front Neurosci; 2012;6:114
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  • INTRODUCTION: This study aimed to estimate the proportion of patients with interstitial cystitis/painful bladder syndrome (IC/BPS) with systemic dysfunction associated co-morbidities such as irritable bowel syndrome (IBS) and fibromyalgia (FM).
  • NIDDK criteria required: pain with bladder filling that improves with emptying, urinary urgency due to discomfort or pain, polyuria >11 times/24 h, and nocturia >2 times/night.
  • High rates of syncope and functional dyspepsia found in the IC/BPS groups merit further study to determine if IC/BPS is part of a diffuse disorder of central, autonomic, and sensory processing affecting multiple organs outside the bladder.

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  • (PMID = 22907988.001).
  • [ISSN] 1662-453X
  • [Journal-full-title] Frontiers in neuroscience
  • [ISO-abbreviation] Front Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3415690
  • [Keywords] NOTNLM ; IC/BPS / co-morbidities / functional gastrointestinal disorders / migraine headache / orthostatic intolerance
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9. |||||..... 51%  Kilicoglu G, Aslan AR, Oztürk M, Karaman IM, Simsek MM: Vesicovaginal reflux: recognition and diagnosis using ultrasound. Pediatr Radiol; 2010 Jan;40(1):114-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vesicovaginal reflux: recognition and diagnosis using ultrasound.
  • BACKGROUND: Vaginal reflux is a functional voiding disorder seen in prepubertal girls without anatomical or neurological abnormality.
  • One girl also had recurrent UTIs treated with antibiotics and was investigated for vesicoureteric reflux with US and voiding cystourethrogram (VCUG).
  • RESULTS: Imaging appearance common to all three girls was a fluid-filled mass posterior to the bladder that disappeared after voiding.
  • A previous VCUG in one girl had shown contrast medium refluxing into the vagina which disappeared after bladder emptying.
  • CONCLUSION: US examination of a distended bladder followed by a post-void study easily provides the correct diagnosis of vesicovaginal reflux by identifying the vagina as the fluid-filled mass.

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  • (PMID = 19847417.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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10. |||||..... 51%  Pannek J: [Diagnosis and therapy of functional disorders of the bladder in persons with diabetes mellitus. What do we actually know?]. Urologe A; 2010 Mar;49(3):381-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and therapy of functional disorders of the bladder in persons with diabetes mellitus. What do we actually know?].
  • Although diabetes mellitus is one of the most common diseases worldwide, only few studies evaluating diagnosis and treatment of lower urinary tract complications of this disorder exist.
  • In addition to diabetic (impaired sensation, reduced detrusor muscle contractility, elevated residual urine), 30-50% of patients can develop an overactive bladder.
  • Basic diagnostics should include patient history, bladder diary, post-void residual and urinalysis.
  • [MeSH-major] Diabetes Complications / diagnosis. Diabetes Complications / therapy. Urinary Bladder Diseases / diagnosis. Urinary Bladder Diseases / therapy


11. |||||..... 50%  Franco I: New ideas in the cause of bladder dysfunction in children. Curr Opin Urol; 2011 Jul;21(4):334-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] New ideas in the cause of bladder dysfunction in children.
  • PURPOSE OF REVIEW: The management of children with urinary incontinence and dysfunctional voiding problems can be very difficult at times.
  • The present array of bladder-oriented treatments are marginally successful and for a long time patients were told that they would outgrow their symptoms.
  • RECENT FINDINGS: It became clear that children with attention deficit disorder were always more difficult to manage than those without neuropsychiatric problems.
  • This research has been conducted primarily in the fields of psychiatry and neuroscience, but there have been some seminal studies that point to a link between defects in the brain and functional urinary problems in children.
  • In this review, we will attempt to outline the reasons why the traditional bowel program works and why there are such a large number of patients with neuropsychiatric problems who have functional urinary problems as children.
  • [MeSH-major] Child Behavior. Enuresis / etiology. Mental Disorders / complications. Urinary Bladder / physiopathology. Urinary Incontinence / etiology
  • [MeSH-minor] Adolescent. Attention Deficit Disorder with Hyperactivity / complications. Attention Deficit Disorder with Hyperactivity / physiopathology. Attention Deficit Disorder with Hyperactivity / psychology. Central Nervous System / physiopathology. Child. Child, Preschool. Humans. Risk Factors. Urodynamics


12. |||||..... 50%  Aliaev IuG, Gadzhieva ZK, Petrovskiĭ NV: [Overactive bladder in patients with infravesical obstruction caused by prostatic adenoma]. Urologiia; 2010 Nov-Dec;(6):10-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Overactive bladder in patients with infravesical obstruction caused by prostatic adenoma].
  • According to the literature, overactive bladder (OB) occurs in 52-80% men with infravesical obstruction (IVO) due to prostatic adenoma, 38% patients retain the disorder after surgical correction of the obstruction.
  • This bladder dysfunction played a leading role in development of IVO complications (vesicoureteral reflux, ureterohydronephrosis) entailing marked disorder of the upper urinary tract disorder--chronic renal failure.
  • Thus, early detection of the cause of urodynamic disorders in IVO patients has a great practical value for functional results of surgery.
  • [MeSH-major] Prostatic Hyperplasia / complications. Urinary Bladder Neck Obstruction / etiology. Urinary Bladder, Overactive / etiology

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  • HSDB. structure - Tamsulosin.
  • HSDB. structure - PHENYLPROPANOLAMINE.
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  • (PMID = 21427986.001).
  • [ISSN] 1728-2985
  • [Journal-full-title] Urologii͡a (Moscow, Russia : 1999)
  • [ISO-abbreviation] Urologiia
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Adrenergic alpha-1 Receptor Antagonists; 0 / Benzhydryl Compounds; 0 / Cresols; 0 / Muscarinic Antagonists; 0 / Sulfonamides; 33RU150WUN / Phenylpropanolamine; G3P28OML5I / tamsulosin; WHE7A56U7K / tolterodine
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13. |||||..... 50%  Warren JW, Clauw DJ: Functional somatic syndromes: sensitivities and specificities of self-reports of physician diagnosis. Psychosom Med; 2012 Nov-Dec;74(9):891-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional somatic syndromes: sensitivities and specificities of self-reports of physician diagnosis.
  • OBJECTIVE: Functional somatic syndromes have no laboratory or pathologic abnormalities and so are diagnosed by symptom-based case definitions.
  • However, many studies, including recent ones, have used self-reports of physician diagnosis rather than the case definitions.
  • Our objective was to determine the sensitivities and specificities of self-report of physician diagnosis for chronic fatigue syndrome (CFS), fibromyalgia (FM), irritable bowel syndrome (IBS), panic disorder, and migraine.
  • METHODS: Each of 312 female patients with incident interstitial cystitis/bladder pain syndrome and matched population-based controls were queried on self-report of physician diagnosis and separately on established case definitions for each of these syndromes.
  • RESULTS: Using the symptom-based case definitions as standards, we found that self-report of physician diagnosis did not identify 90% of the controls who had CFS, 77% who had FM, 69% who had IBS, 43% who had panic disorder, and 23% who had migraine.
  • Findings in one cohort (controls) were confirmed in another (patients with interstitial cystitis/bladder pain syndrome).
  • CONCLUSIONS: Self-report of physician diagnosis did not identify most of the three most venerable functional somatic syndromes, IBS, FM, and, especially, CFS; nor did it identify substantial minorities of individuals with panic disorder and migraine.
  • Self-report of physician diagnosis was particularly poor in recognizing persons with multiple syndromes.
  • [MeSH-major] Self Report. Somatoform Disorders / diagnosis. Somatoform Disorders / psychology
  • [MeSH-minor] Adult. Comorbidity. Cystitis, Interstitial / diagnosis. Cystitis, Interstitial / epidemiology. Cystitis, Interstitial / psychology. Fatigue Syndrome, Chronic / diagnosis. Fatigue Syndrome, Chronic / epidemiology. Fatigue Syndrome, Chronic / psychology. Female. Fibromyalgia / diagnosis. Fibromyalgia / epidemiology. Fibromyalgia / psychology. Humans. Irritable Bowel Syndrome / diagnosis. Irritable Bowel Syndrome / epidemiology. Irritable Bowel Syndrome / psychology. Middle Aged. Migraine Disorders / diagnosis. Migraine Disorders / epidemiology. Migraine Disorders / psychology. Panic Disorder / diagnosis. Panic Disorder / epidemiology. Panic Disorder / psychology. Pelvic Pain / diagnosis. Pelvic Pain / epidemiology. Pelvic Pain / psychology. Sensitivity and Specificity. Sex Factors. Syndrome

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  • [CommentIn] Psychosom Med. 2012 Nov-Dec;74(9):882 [23107838.001]
  • (PMID = 23071343.001).
  • [ISSN] 1534-7796
  • [Journal-full-title] Psychosomatic medicine
  • [ISO-abbreviation] Psychosom Med
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK 064880; United States / NIDDK NIH HHS / DK / U01 DK 066136
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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14. |||||..... 49%  Schops W, Jungmann O, Zumbe J, Zellner M, Hengstler JG, Golka K: Assessment criteria for compensation of occupational bladder cancer. Front Biosci (Elite Ed); 2013;5:653-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment criteria for compensation of occupational bladder cancer.
  • In Germany, more than 100 bladder tumor cases are annually recognized as occupational disease and compensated, given that medical experts regard exposure to carcinogenic aromatic amines as a likely cause of cancer.
  • The amount of compensation is initially based on the tumor staging and grading at the time of initial diagnosis ("basic MdE") (MdE--reduction of earning capacity) and is adapted after a recurrence-free period of 2 and 5 years, respectively.
  • In the event of treatment or tumor-related secondary conditions, the monthly compensation increases based on the severity of the objectified functional disorder.
  • [MeSH-major] Compensation and Redress. Occupational Diseases / economics. Symptom Assessment / economics. Urinary Bladder Neoplasms / economics. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Erectile Dysfunction / economics. Erectile Dysfunction / etiology. Germany. Humans. Kidney / pathology. Male. Urinary Bladder / pathology. Urinary Tract Infections / economics. Urinary Tract Infections / etiology


15. |||||..... 49%  Gheinani AH, Burkhard FC, Monastyrskaya K: Deciphering microRNA code in pain and inflammation: lessons from bladder pain syndrome. Cell Mol Life Sci; 2013 Oct;70(20):3773-89
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Deciphering microRNA code in pain and inflammation: lessons from bladder pain syndrome.
  • Bladder pain syndrome/interstitial cystitis (BPS/IC) is a clinical syndrome of pelvic pain and urinary urgency/frequency in the absence of a specific cause.
  • This review projects the miRNA profiling and functional data originating from the research in bladder cancer and immune-mediated diseases on the BPS-specific miRNAs with the aim to gain new insight into the pathogenesis of this enigmatic disorder, and highlighting the common regulatory mechanisms of pain and inflammation.
  • [MeSH-major] Cystitis, Interstitial / genetics. Inflammation / pathology. MicroRNAs / metabolism. Urinary Bladder / pathology

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  • (PMID = 23463234.001).
  • [ISSN] 1420-9071
  • [Journal-full-title] Cellular and molecular life sciences : CMLS
  • [ISO-abbreviation] Cell. Mol. Life Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / MicroRNAs
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16. |||||..... 49%  Warren JW, Clauw DJ, Wesselmann U, Langenberg PW, Howard FM, Morozov V: Sexuality and reproductive risk factors for interstitial cystitis/painful bladder syndrome in women. Urology; 2011 Mar;77(3):570-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sexuality and reproductive risk factors for interstitial cystitis/painful bladder syndrome in women.
  • OBJECTIVES: To determine whether interstitial cystitis/painful bladder syndrome (IC/PBS) in women is associated with antecedent sexual and reproductive characteristics.
  • METHODS: By multivariate analyses, 312 incident IC/PBS cases were compared with matched controls for antecedent sexual and reproductive characteristics, adjusted by demographics, previous surgery, and nonbladder syndromes (NBSs), such as chronic pelvic pain, irritable bowel syndrome, and panic disorder.
  • This finding suggests that knowledge of the pathogeneses of these NBSs, many of which are functional somatic syndromes, might reveal that of IC/PBS.

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  • [Copyright] Copyright © 2011 Elsevier Inc. All rights reserved.
  • (PMID = 21215994.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral, Hormonal; 0 / Estrogens; 0 / Progestins
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17. |||||..... 49%  Griffiths DJ: Use of functional imaging to monitor central control of voiding in humans. Handb Exp Pharmacol; 2011;(202):81-97
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of functional imaging to monitor central control of voiding in humans.
  • Bladder problems are frequently disorders of control, which is exercised from the brain.
  • In such disorders, brain responses to bladder events are abnormal; therapy is accompanied by regional changes that may be measured by functional imaging and used to monitor the effect of treatment.
  • The regional responses may be understood in terms of a tentative model of the bladder control system.
  • The model helps also to interpret alterations in brain behavior (as imaged by functional scanning) that occur when afferent signals from bladder or urethra are changed experimentally or by an underlying disorder or treatment, for example, overactive bladder (urge/urgency incontinence).
  • [MeSH-major] Brain Mapping. Central Nervous System / physiopathology. Urinary Bladder / innervation. Urinary Bladder Diseases / diagnosis

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  • (PMID = 21290223.001).
  • [ISSN] 0171-2004
  • [Journal-full-title] Handbook of experimental pharmacology
  • [ISO-abbreviation] Handb Exp Pharmacol
  • [Language] eng
  • [Grant] United States / NIA NIH HHS / AG / R01AG020629; United States / NIA NIH HHS / AG / R03AG25166
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
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18. |||||..... 49%  Peters KM, Killinger KA, Mounayer MH, Boura JA: Are ulcerative and nonulcerative interstitial cystitis/painful bladder syndrome 2 distinct diseases? A study of coexisting conditions. Urology; 2011 Aug;78(2):301-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Are ulcerative and nonulcerative interstitial cystitis/painful bladder syndrome 2 distinct diseases? A study of coexisting conditions.
  • OBJECTIVES: Coexisting conditions associated with interstitial cystitis/painful bladder syndrome (IC/PBS) have not been fully explored by IC/PBS subtypes.
  • Standardized questionnaires assessed IC/PBS symptoms (Interstitial Cystitis Symptom/Problem Indexes [ICSI-PI]) and for undiagnosed fibromyalgia, irritable bowel syndrome, and depression (Symptom Intensity Score [SIS]; Rome III Functional Bowel Questionnaire; Center for Epidemiologic Studies Depression Scale [CES-D]).
  • When N-ULC and ULC IC/PBS patients were compared, more N-ULC IC/PBS patients had fibromyalgia (P = .03), migraines (P = .03), temporomandibular joint disorder (P < .01), and higher CES-D (P = .02) and SIS scores (P = .01).
  • The ULC IC/PBS group voided more frequently during the daytime (P = .03) and nighttime (P < .01) and had smaller mean bladder capacity than N-ULC (P < .01).
  • [MeSH-minor] Female. Humans. Middle Aged. Urinary Bladder Diseases / complications


19. |||||..... 49%  Delgado Oliva FJ, Caballero Romeo JP, García Serrado D, Prieto Chaparro L, Carro Rubias C, Chillón Sempere S, De Paz Cruz L, De Nova Sánchez E: [Urinary incontinence after radical prostatectomy: surgical technique historic evolution and present functional outcomes]. Arch Esp Urol; 2009 Dec;62(10):809-18
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  • [Title] [Urinary incontinence after radical prostatectomy: surgical technique historic evolution and present functional outcomes].
  • [Transliterated title] Incontinencia urinaria tras prostatectomía radical: evolución histórica de la técnica quirúrgica y estado actual del resultado funcional.
  • Radical surgery must achieve good oncological and functional outcomes with early continence and potency.
  • To analyze functional outcomes regarding urinary incontinence (UI) after RP in our centre in the last ten years.
  • CONCLUSIONS: Urinary incontinence is a low frequency disorder in patients who undergo RP.
  • [MeSH-minor] Aged. Anastomosis, Surgical / adverse effects. Constriction, Pathologic / etiology. Constriction, Pathologic / therapy. Dilatation. Humans. Male. Middle Aged. Retrospective Studies. Time Factors. Urethra / surgery. Urinary Bladder / surgery


20. |||||..... 48%  Warren JW, Langenberg P, Clauw DJ: The number of existing functional somatic syndromes (FSSs) is an important risk factor for new, different FSSs. J Psychosom Res; 2013 Jan;74(1):12-7
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  • [Title] The number of existing functional somatic syndromes (FSSs) is an important risk factor for new, different FSSs.
  • OBJECTIVE: The objective of this study is to test the hypothesis that the number of functional somatic syndromes (FSSs) predicts new, additional FSSs.
  • METHODS: In a recent case-control study of interstitial cystitis/painful bladder syndrome (IC/PBS), we used symptom-based consensus definitions to identify these FSSs: fibromyalgia (FM), chronic fatigue syndrome (CFS), irritable bowel syndrome (IBS), chronic pelvic pain, migraine, sicca syndrome and panic disorder.
  • [MeSH-major] Cystitis, Interstitial / diagnosis. Somatoform Disorders / diagnosis. Somatoform Disorders / epidemiology

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  • [Copyright] Copyright © 2012 Elsevier Inc. All rights reserved.
  • [CommentIn] J Psychosom Res. 2013 Aug;75(2):190 [23915779.001]
  • [CommentIn] J Psychosom Res. 2013 Aug;75(2):191 [23915780.001]
  • (PMID = 23272983.001).
  • [ISSN] 1879-1360
  • [Journal-full-title] Journal of psychosomatic research
  • [ISO-abbreviation] J Psychosom Res
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK 064880; United States / NIDDK NIH HHS / DK / U01 DK 066136
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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21. |||||..... 48%  Ramamurthy HR, Kanitkar M: Non invasive urodynamic assessment in children--are they reliable? Validation of non-invasive urodynamics in children with functional voiding disorders. Indian J Pediatr; 2010 Dec;77(12):1400-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non invasive urodynamic assessment in children--are they reliable? Validation of non-invasive urodynamics in children with functional voiding disorders.
  • OBJECTIVES: To validate the non-invasive tests that can predict the type of bladder dysfunction normally diagnosed by invasive urodynamics.
  • The commonest disorder was detrusor instability in 28 (68.2%).
  • Dysynergic voiding was noted in 8 (19.5%).
  • Nocturnal enuresis with day time symptoms, holding maneuvers, small frequent voiding pattern (p<0.05) and a small capacity bladder with insignificant residue (p=0.0003) predicts detrusor instability.
  • Straining (p=0.0006), large capacity bladder with significant post void residue in the absence of vesicouretric reflux (p<0.05) predicts dysyneric voiding.
  • On combining the various non-invasive tests and validating them against invasive urodynamics in diagnosing detrusor instability and dysnergic voiding, they have a sensitivity of 88.4% and 87.5%, specificity of 72.7% and 69.2%, positive predictive value of 0.88 and 0.63 and positive likelihood ratio of 3.1 & 2.2 respectively.
  • CONCLUSIONS: Functional voiding disorders can be diagnosed with reasonable accuracy by minimally invasive methods.
  • [MeSH-major] Urination Disorders / diagnosis. Urodynamics

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  • (PMID = 20844992.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] India
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22. |||||..... 47%  Krums LM, Sabel'nikova EA, Parfenov AI: [Functional condition of the stomach, pancreas, liver and gallbladder in celiac disease]. Ter Arkh; 2011;83(2):20-4
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  • [Title] [Functional condition of the stomach, pancreas, liver and gallbladder in celiac disease].
  • AIM: To study condition of the stomach, gall-bladder, pancreas, liver in celiac disease (CD) and contribution of their dysfunction to clinical presentation of CD symptoms.
  • There were an inert type of pancreatic enzyme secretion, gall-bladder hypokinesia or atony.
  • Gall-bladder contracted only after intravenous injection of cholecystokinin.
  • Decline in excretory pancreatic function, slow enzyme secretion, marked hypokinesia of the gall-bladder, hyperenzymemia and steatohepatitis as manifestations of hepatic pathology result in dramatic disorder of digestion and absorption of food substances.

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  • (PMID = 21516844.001).
  • [ISSN] 0040-3660
  • [Journal-full-title] Terapevticheskiĭ arkhiv
  • [ISO-abbreviation] Ter. Arkh.
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Biological Markers; 0 / Gastrins; EC 3.1.1.3 / Lipase; EC 3.2.1.- / Amylases; EC 3.4.21.4 / Trypsin
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23. |||||..... 47%  Elneil S: Complex pelvic floor failure and associated problems. Best Pract Res Clin Gastroenterol; 2009;23(4):555-73
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  • Its dual role is to provide support for the pelvic viscera (bladder, bowel and uterus) and maintain functional integrity of these organs.
  • It can affect one or all the three compartments of the pelvic floor, often resulting in prolapse and functional disturbance of the bladder (urinary incontinence and voiding dysfunction), rectum (faecal incontinence), vagina and/or uterus (sexual dysfunction).


24. |||||..... 46%  Ballisty MM, Braithwaite KA, Shehata BM, Dickson PN: Imaging findings in megacystis-microcolon-intestinal hypoperistalsis syndrome. Pediatr Radiol; 2013 Apr;43(4):454-9
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  • Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is a rare and frequently lethal form of severe functional intestinal obstruction more commonly found in girls.
  • Imaging features characteristic of this disease include a large dilated bladder, microcolon and intestinal dysmotility.
  • Because presenting clinical and imaging features can mimic other causes of neonatal bowel obstruction, we compiled examples of this disorder to help the pediatric radiologist recognize imaging findings associated with MMIHS and aid in the development of a long-term management plan and in counseling the family regarding implications of this disorder.
  • We reviewed recent and historical literature relevant to MMIHS and present the imaging and clinical features of four patients with MMIHS treated at our institution as examples of this uncommon disorder.
  • [MeSH-major] Abnormalities, Multiple / diagnosis. Image Enhancement / methods. Intestinal Pseudo-Obstruction / diagnosis. Tomography, X-Ray Computed / methods. Ultrasonography / methods
  • [MeSH-minor] Colon / abnormalities. Female. Humans. Infant. Infant, Newborn. Male. Urinary Bladder / abnormalities


25. |||||..... 46%  Lai HH, North CS, Andriole GL, Sayuk GS, Hong BA: Polysymptomatic, polysyndromic presentation of patients with urological chronic pelvic pain syndrome. J Urol; 2012 Jun;187(6):2106-12
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  • PURPOSE: Somatization disorder has been described in several comorbid functional syndromes of urological chronic pelvic pain syndrome, such as irritable bowel syndrome.
  • We investigated whether a subset of patients with urological chronic pelvic pain syndrome may have the polysymptomatic, polysyndromic presentation pattern that is common in somatization disorder.
  • The 2 operational tools used were the Perley-Guze derived symptom checklist and the somatic symptom algorithm used for Diagnostic and Statistical Manual, 4th Edition, Text Revision somatization disorder criteria.
  • RESULTS: Female patients with urological chronic pelvic pain syndrome (interstitial cystitis/bladder pain syndrome) reported significantly more nonpain symptoms and pain symptoms outside the pelvis than control female urology patients (p=0.0016 and 0.0018, respectively).
  • In contrast, male patients with urological chronic pelvic pain syndrome (interstitial cystitis/bladder pain syndrome and/or chronic prostatitis/chronic pelvic pain syndrome) did not report more extrapelvic pain than male controls (p=0.89).
  • The checklist may be valuable to assess patients for this polysymptomatic, polysyndromic symptom pattern, which is common in somatization disorder.
  • Recognizing this polysymptomatic, polysyndromic presentation will prompt clinicians to investigate further to determine whether somatization disorder may be an underlying diagnosis in a small subset of patients with urological chronic pelvic pain syndrome who complain of numerous extrapelvic symptoms.
  • [MeSH-major] Chronic Pain / diagnosis. Pelvic Pain / diagnosis. Somatoform Disorders / diagnosis

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  • [Copyright] Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
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  • (PMID = 22503014.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK082315; United States / NIDDK NIH HHS / DK / K23 DK084113; United States / NIDDK NIH HHS / DK / U01 DK082315
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS458733; NLM/ PMC3957225
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26. |||||..... 46%  DiBaise JK, Richmond BK, Ziessman HA, Everson GT, Fanelli RD, Maurer AH, Ouyang A, Shamamian P, Simons RJ, Wall LA, Weida TJ, Tulchinsky M: Cholecystokinin-cholescintigraphy in adults: consensus recommendations of an interdisciplinary panel. Clin Nucl Med; 2012 Jan;37(1):63-70
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  • At present, it is used most commonly to identify patients with suspected functional gallbladder disorder.
  • The panel emphasized the need for a large, multicenter, prospective clinical trial to establish the utility of CCK-CS in the diagnosis of functional gallbladder disease.
  • Although not without controversy regarding its clinical utility, the primary indication for CCK-CS at present is the well-selected patient with suspected functional gallbladder disorder.
  • [MeSH-major] Cholecystokinin / diagnostic use. Practice Guidelines as Topic. Radionuclide Imaging / standards. Urinary Bladder Diseases / radionuclide imaging

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  • (PMID = 22157031.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Consensus Development Conference; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 9011-97-6 / Cholecystokinin
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27. |||||..... 46%  Komiakov BK, Strokova LA: [Classification of hydroureteronephrosis by ultrasonography findings]. Urologiia; 2011 Mar-Apr;(2):13-9
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  • A complex examination including blood and urine biochemistry, pyelomanometry, x-ray-radionuclide and endoscopic investigations of the urinary tract as well as ultrasonography with estimation of morphometric and functional parameters of different parts of the urinary tract was conducted in 525 patients with various diseases of the pelvic ureter and urinary bladder complicated by hydroureteronephrosis (HUN) and 50 healthy controls.
  • The proposed 4-stage HUN classification based finally only on ultrasonography data describes not only severity of anatomic changes but, indirectly, functional reserves of the upper urinary tract.
  • According to the stage of urodynamic disorder, therapeutic policy is proposed.

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  • (PMID = 21815452.001).
  • [ISSN] 1728-2985
  • [Journal-full-title] Urologii͡a (Moscow, Russia : 1999)
  • [ISO-abbreviation] Urologiia
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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28. |||||..... 46%  Rooney A, Statham PF, Stone J: Cauda equina syndrome with normal MR imaging. J Neurol; 2009 May;256(5):721-5
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  • While some may have had an alternative organic cause, we propose that these symptoms may have a "functional" origin in many patients.
  • [MeSH-major] Cauda Equina / pathology. Conversion Disorder / diagnosis. Lumbar Vertebrae / pathology. Magnetic Resonance Imaging. Polyradiculopathy / pathology. Spinal Canal / pathology
  • [MeSH-minor] Adult. Causality. Cohort Studies. Diagnosis, Differential. Female. Humans. Hypesthesia / etiology. Male. Middle Aged. Muscle Weakness / etiology. Psychophysiologic Disorders / diagnosis. Retrospective Studies. Urinary Bladder, Neurogenic / etiology. Urinary Incontinence / etiology

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  • (PMID = 19240964.001).
  • [ISSN] 1432-1459
  • [Journal-full-title] Journal of neurology
  • [ISO-abbreviation] J. Neurol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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29. |||||..... 46%  Noël S, Claeys S, Hamaide A: Acquired urinary incontinence in the bitch: update and perspectives from human medicine. Part 2: The urethral component, pathophysiology and medical treatment. Vet J; 2010 Oct;186(1):18-24
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  • Various pathologies can affect the bladder and/or urethral contractility causing signs of urinary incontinence.
  • The pathophysiology and current recommended medical treatment options for USMI and cases of modified urethral tonicity due to a neurological disorder or functional outlet obstruction are discussed.

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20655776.001).
  • [ISSN] 1532-2971
  • [Journal-full-title] Veterinary journal (London, England : 1997)
  • [ISO-abbreviation] Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
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30. |||||..... 46%  Hirakawa H, Ueno S, Matuda H, Hinoki T, Kato Y: Effect of the herbal medicine dai-kenchu-to on gastrointestinal motility in patients with megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) and chronic idiopathic intestinal pseudo-obstruction (CIIP): report of two cases. Tokai J Exp Clin Med; 2009 Apr;34(1):28-33
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  • MMIHS and CIIP are severe motility disorder associated with high morbidity.
  • The aim of this study was to evaluate the effect of DKT on functional intestinal obstruction.
  • [MeSH-minor] Abnormalities, Multiple / drug therapy. Abnormalities, Multiple / pathology. Colon / abnormalities. Colon / pathology. Female. Genetic Diseases, X-Linked / drug therapy. Genetic Diseases, X-Linked / pathology. Humans. Infant. Intestinal Pseudo-Obstruction / congenital. Intestinal Pseudo-Obstruction / drug therapy. Intestinal Pseudo-Obstruction / pathology. Medicine, East Asian Traditional. Urinary Bladder / abnormalities. Urinary Bladder / pathology. Young Adult


31. |||||..... 46%  Purandare C, Shitole DG, Belle V, Kedari A, Bora N, Joshi M: Therapeutic potential of autologous stem cell transplantation for cerebral palsy. Case Rep Transplant; 2012;2012:825289
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  • CP was considered as a noncurable, nonreparative disorder, but stem cell therapy offers a potential treatment for CP.
  • Bowel and bladder control has been achieved.
  • Conclusion. In this study, we report that intrathecal infusion of autologous BMMNCs seems to be feasible, effective, and safe with encouraging functional outcome improvements in CP patient.

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  • [Cites] Cell Transplant. 2008;16(10):993-1005 [18351015.001]
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  • (PMID = 23259143.001).
  • [ISSN] 2090-6943
  • [Journal-full-title] Case reports in transplantation
  • [ISO-abbreviation] Case Rep Transplant
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3505957
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32. |||||..... 46%  Sibert L, Safsaf A, Rigaud J, Delavierre D, Labat JJ: [Pelvic sexual pain]. Prog Urol; 2010 Nov;20(12):967-72
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  • Deep dyspareunia must start investigations in search of pelvic organs disorders, endometriosis, painful bladder syndrome adhesions.
  • Vaginismus can be linked to a local disorder, but can also be caused by an excess of nociception.
  • In the male subject, painful ejaculation must start investigation in search of a local urological disorder.
  • In the absence of systematically researched organic disorder, these pains can be part of functional disorders, in which case a global assessment must be undergone, by taking into account all aspects of the pain, including emotional aspects.
  • [MeSH-minor] Dyspareunia / diagnosis. Dyspareunia / etiology. Ejaculation. Female. Humans. Male

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 21056373.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
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33. |||||..... 46%  Kindler LL, Bennett RM, Jones KD: Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders. Pain Manag Nurs; 2011 Mar;12(1):15-24
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  • A literature search was performed through PubMed and Ovid using the terms fibromyalgia, temporomandibular joint disorder, irritable bowel syndrome, irritable bladder/interstitial cystitis, headache, chronic low back pain, chronic neck pain, functional syndromes, and somatization.

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  • [Copyright] Copyright © 2011 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.
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  • (PMID = 21349445.001).
  • [ISSN] 1532-8635
  • [Journal-full-title] Pain management nursing : official journal of the American Society of Pain Management Nurses
  • [ISO-abbreviation] Pain Manag Nurs
  • [Language] eng
  • [Grant] United States / NINR NIH HHS / NR / F31 NR010301-01; United States / NINR NIH HHS / NR / F31 NR010301-02; United States / NINR NIH HHS / NR / NR010301-01; United States / NINDS NIH HHS / NS / NS045551; United States / NINDS NIH HHS / NS / T32 NS045551; United States / NINDS NIH HHS / NS / T32 NS045551-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS156761; NLM/ PMC3052797
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34. |||||..... 46%  Nakipoglu GF, Ozgirgin N: Urodynamic evaluation and rehabilitation outcomes in transverse myelitis. Neurosciences (Riyadh); 2009 Jan;14(1):37-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To evaluate micturition abnormalities in patients with transverse myelitis (TM) using urodynamic studies, and to record functional outcomes of these patients after the rehabilitation program.
  • Neurologic bladder types and treatments, and functional levels of the patients after the rehabilitation program were recorded.
  • Urodynamic studies showed hypocompliant bladder in 2 patients, detrusor sphincter dyssynergia in 22, detrusor hyperreflexia in 16, and only sphincter disorder in 6 patients.
  • Functional outcomes on discharge were independent ambulation in 8, ambulation with crutches in 16, ambulation with knee-ankle-foot orthesis and crutches in 4, therapeutic ambulation in 2, wheelchair in 16.
  • CONCLUSION: Rehabilitation is important in patients with TM to continue the urinary continence and to preserve renal function, to obtain functional independence and to prevent complications.

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  • (PMID = 21048571.001).
  • [ISSN] 1319-6138
  • [Journal-full-title] Neurosciences (Riyadh, Saudi Arabia)
  • [ISO-abbreviation] Neurosciences (Riyadh)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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35. |||||..... 46%  Machino M, Yukawa Y, Hida T, Ito K, Nakashima H, Kanbara S, Morita D, Kato F: Persistent physical symptoms after laminoplasty: analysis of postoperative residual symptoms in 520 patients with cervical spondylotic myelopathy. Spine (Phila Pa 1976); 2012 May 15;37(11):932-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SUMMARY OF BACKGROUND DATA: CSM is an increasingly common neurological disorder of the geriatric population.
  • Each functional improvement was expressed by the recovery rate (RR) of the Japanese Orthopedic Association score.
  • The mean recovery rates of sensory function of the upper extremity, lower extremity, and trunk were 48.1%, 56.6%, and 54.6%, respectively, and that of urinary bladder function was 59.6%.


36. |||||..... 46%  Fiaschetti V, Squillaci E, Pastorelli D, Rascioni M, Funel V, Salimbeni C, Fanucci E, Simonetti G: Dynamic MR defecography with an open-configuration, low-field, tilting MR system in patients with pelvic floor disorders. Radiol Med; 2011 Jun;116(4):620-33
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  • MATERIALS AND METHODS: Eighteen female patients with a diagnosis of pelvic floor disorder (physical examination and conventional defecography) underwent dynamic MR defecography (MRD) with a 0.25-T tilting MR system (G-scan, Esaote).
  • Images were obtained after administration of contrast agent into the rectum, bladder and vagina in both the orthostatic and supine positions.
  • RESULTS: Good image quality was obtained in 15/18 patients; three presented severe artefacts due to motion, and three had incontinence, which hampered the functional studies.
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Pelvic Floor / pathology. Rectocele / diagnosis. Rectocele / physiopathology. Young Adult


37. |||||..... 46%  Chiarelli N, Ritelli M, Zoppi N, Benini A, Borsani G, Barlati S, Colombi M: Characterization and expression pattern analysis of the facilitative glucose transporter 10 gene (slc2a10) in Danio rerio. Int J Dev Biol; 2011;55(2):229-36
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  • Mutations in the human SLC2A10 gene cause arterial tortuosity syndrome (ATS), a rare autosomal recessive connective tissue disorder.
  • The gene encodes Glut10, a 513 amino acid protein that maintains the 12 transmembrane domain structure typical of the GLUTs family, and shares the specific functional motifs involved in sugar transport with the vertebrate GLUT10.
  • In later embryonic stages, slc2a10 mRNA was detected in the otic vesicles, hatching gland cells, pectoral fin, posterior tectum and swim bladder.

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  • (PMID = 21553381.001).
  • [ISSN] 1696-3547
  • [Journal-full-title] The International journal of developmental biology
  • [ISO-abbreviation] Int. J. Dev. Biol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ HM560591/ HM560592
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / 5' Untranslated Regions; 0 / Glucose Transport Proteins, Facilitative; 0 / Protein Isoforms; 0 / RNA, Messenger; 0 / Slc2a10 protein, zebrafish
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38. |||||..... 46%  Lei D, Ma J, Du X, Shen G, Tian M, Li G: Spontaneous brain activity changes in children with primary monosymptomatic nocturnal enuresis: a resting-state fMRI study. Neurourol Urodyn; 2012 Jan;31(1):99-104
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  • Primary monosymptomatic nocturnal enuresis (PMNE) is a common disorder in school-aged children.
  • In this work, resting-state functional magnetic resonance imaging (fMRI) was used to investigate changes in spontaneous brain activity in children with PMNE.
  • Abnormalities in BA 10 and the inferior frontal gyrus may affect children's decision-making with regard to voiding; abnormalities in the midbrain in PMNE children may influence the internal signal transmission in their bladder control network.

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  • [Copyright] Copyright © 2011 Wiley Periodicals, Inc.
  • (PMID = 22038619.001).
  • [ISSN] 1520-6777
  • [Journal-full-title] Neurourology and urodynamics
  • [ISO-abbreviation] Neurourol. Urodyn.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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39. |||||..... 46%  Novak I, Hines M, Goldsmith S, Barclay R: Clinical prognostic messages from a systematic review on cerebral palsy. Pediatrics; 2012 Nov;130(5):e1285-312
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  • OBJECTIVE: To summarize evidence on the rates of co-occurring impairments, diseases, and functional limitations with cerebral palsy into succinct clinical messages.
  • Articles were appraised, analyzing design, participants, level of evidence, rates of impairments, and functional implications.
  • CONCLUSIONS: Among children with cerebral palsy, 3 in 4 were in pain; 1 in 2 had an intellectual disability; 1 in 3 could not walk; 1 in 3 had a hip displacement; 1 in 4 could not talk; 1 in 4 had epilepsy; 1 in 4 had a behavior disorder; 1 in 4 had bladder control problems; 1 in 5 had a sleep disorder; 1 in 5 dribbled; 1 in 10 were blind; 1 in 15 were tube-fed; and 1 in 25 were deaf.


40. |||||..... 46%  Abou Zeid NE, Weinshenker BG, Keegan BM: Gait apraxia in multiple sclerosis. Can J Neurol Sci; 2009 Sep;36(5):562-5
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  • BACKGROUND: Gait apraxia is a gait disorder not attributable to motor, cerebellar, or sensory dysfunction.
  • OBJECTIVE: To describe 15 patients with gait apraxia resulting from MS as their major functional impairment.
  • EXCLUSION CRITERIA: alternative disorder causing apraxia, predominantly spastic/ataxic gait disorder.
  • Cognitive dysfunction was present in 11 (73%) and neurogenic bladder dysfunction in 14 (93%).
  • CONCLUSION: Gait apraxia can cause significant functional impairment in MS patients, and may be underrecognized.


41. |||||..... 46%  Paznekas WA, Karczeski B, Vermeer S, Lowry RB, Delatycki M, Laurence F, Koivisto PA, Van Maldergem L, Boyadjiev SA, Bodurtha JN, Jabs EW: GJA1 mutations, variants, and connexin 43 dysfunction as it relates to the oculodentodigital dysplasia phenotype. Hum Mutat; 2009 May;30(5):724-33
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  • The predominantly autosomal dominant disorder, oculodentodigital dysplasia (ODDD) has high penetrance with intra- and interfamilial phenotypic variability.
  • Neurological problems, including dysarthria, neurogenic bladder disturbances, spastic paraparesis, ataxia, anterior tibial muscle weakness, and seizures, are known to occur as well as conductive hearing loss, cardiac defects, and anomalies of the skin, hair, and nails.
  • Mutations resulting in ODDD occur in each of the nine domains of the Cx43 protein, and we review our functional experiments and those in the literature, examining the effects of 13 different Cx43 mutations upon gap junction activity.


42. ||||...... 41%  Zhang Y, Sheng J, Hou C, Lin H: [Microstructural study on detrusor muscle after bladder functional reconstruction for atonic bladder caused by medullary cone injury in rats]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2013 Jul;27(7):836-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Microstructural study on detrusor muscle after bladder functional reconstruction for atonic bladder caused by medullary cone injury in rats].
  • OBJECTIVE: To study the microstructural change of detrusor muscle and neuromuscular junction (NMJ) after bladder functional reconstruction for atonic bladder caused by medullary cone injury and to discuss the feasibility of bladder functional reconstruction for improving the detrusor muscle degeneration.
  • No treatment was given in normal group; the medullary cone injury was established by sharp transection of spinal cord at L4,5 levels in control group; and the anastomosis of bilateral L5 ventral root (VR)-S2 VR and L5 dorsal root (DR)-S2 DR was performed for bladder functional reconstruction after modeling of medullary cone injury in experimental group.
  • HE staining and Masson trichrome staining indicated that the muscle fibers arranged in disorder with gradually aggravated atrophy and gradually increased connective tissue in control group, while the shape of the detrusor muscle recovered with no increased connective tissue at 4, 5, and 6 months after operation in experimental group; there was significant difference in cross-sectional area of detrusor muscle and percentage of connective tissue between normal group and experimental group, and between normal group and control group at each time point (P < 0.05).
  • CONCLUSION: The reconstruction of bladder function with L5 nerve roots above the paraplegic plane can effectively inhibit the degeneration of detrusor muscle and improve its microstructural changes after medullary cone injury.
  • [MeSH-major] Muscle, Smooth / pathology. Neuromuscular Junction / pathology. Spinal Cord Injuries / complications. Spinal Nerve Roots / surgery. Urinary Bladder, Neurogenic / surgery
  • [MeSH-minor] Animals. Disease Models, Animal. Feasibility Studies. Male. Muscle Fibers, Skeletal / pathology. Muscle Fibers, Skeletal / ultrastructure. Random Allocation. Rats. Rats, Sprague-Dawley. Reconstructive Surgical Procedures / methods. Urinary Bladder / innervation. Urinary Bladder / physiopathology. Urinary Bladder / surgery. Urination

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  • (PMID = 24063173.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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43. ||||...... 39%  Birder LA: Urinary bladder, cystitis and nerve/urothelial interactions. Auton Neurosci; 2014 May;182:89-94
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  • [Title] Urinary bladder, cystitis and nerve/urothelial interactions.
  • A hallmark of functional pain syndromes, such as bladder pain syndrome/interstitial cystitis (BPS/IC) is pain in the absence of demonstrable infection or pathology of the viscera or associated nerves.
  • This condition is characterized by suprapubic pain, associated with bladder filling and can also be accompanied by a persistent strong desire to void, increased frequency of urination and nocturia.
  • Severe cases of this disorder, which affects primarily women, can have considerable impact on the quality of life of patients due to extreme pain and urinary frequency, which are often difficult to treat.
  • Theories explaining the pathology of bladder pain syndrome are many and include an altered bladder lining and possible contribution of a bacterial agent.

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  • [Copyright] Copyright © 2013 Elsevier B.V. All rights reserved.
  • (PMID = 24412640.001).
  • [ISSN] 1872-7484
  • [Journal-full-title] Autonomic neuroscience : basic & clinical
  • [ISO-abbreviation] Auton Neurosci
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK057284; United States / NIDDK NIH HHS / DK / R37 DK054824
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS552115 [Available on 05/01/15]; NLM/ PMC3989437 [Available on 05/01/15]
  • [Keywords] NOTNLM ; Autonomic nervous system / Sensory function / Transducer function / Urothelium
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44. ||||...... 38%  Thorson W, Diaz-Horta O, Foster J 2nd, Spiliopoulos M, Quintero R, Farooq A, Blanton S, Tekin M: De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis. Hum Genet; 2014 Jun;133(6):737-42
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  • [Title] De novo ACTG2 mutations cause congenital distended bladder, microcolon, and intestinal hypoperistalsis.
  • Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is characterized by prenatal-onset distended urinary bladder with functional intestinal obstruction, requiring extensive surgical intervention for survival.
  • While it is believed to be an autosomal recessive disorder, most cases are sporadic.
  • Through whole-exome sequencing in a child with MMIHS, we identified a de novo mutation, p.R178L, in the gene encoding the smooth muscle gamma-2 actin, ACTG2.
  • We subsequently detected another de novo ACTG2 mutation, p.R178C, in an additional child with MMIHS.
  • Actg2 transcripts were primarily found in murine urinary bladder and intestinal tissues.
  • Structural analysis and functional experiments suggested that both ACTG2 mutants interfere with proper polymerization of ACTG2 into thin filaments, leading to impaired contractility of the smooth muscle.
  • [MeSH-major] Abnormalities, Multiple / genetics. Actins / genetics. Colon / abnormalities. Intestinal Pseudo-Obstruction / genetics. Mutation. Urinary Bladder / abnormalities

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  • (PMID = 24337657.001).
  • [ISSN] 1432-1203
  • [Journal-full-title] Human genetics
  • [ISO-abbreviation] Hum. Genet.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / R01-GM083897
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / ACTG2 protein, human; 0 / Actins; Megacystis microcolon intestinal hypoperistalsis syndrome
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45. ||||...... 35%  Tambaro S, Casu MA, Mastinu A, Lazzari P: Evaluation of selective cannabinoid CB(1) and CB(2) receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis. Eur J Pharmacol; 2014 Apr 15;729:67-74
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  • Interstitial cystitis is a debilitating bladder inflammation disorder.
  • Recent experimental results have shown a functional role of the endocannabinoid system in urinary bladder.
  • Bladder inflammation was induced in mice by lipopolysaccharide (LPS) and whole bladders were removed 24h later.
  • LPS induced a significant increase of the contractile amplitude in spontaneous activity and a hypersensitivity to exogenous acetylcholine-induced contraction of whole-isolated bladder.
  • Interestingly, JWH015, but not ACEA, antagonized LPS-induced bladder inflammation.
  • LPS treatment increased expression of bladder CB2 but not CB1 mRNA.
  • Taken together, these findings strongly suggest that modulation of the cannabinoid CB2 receptors might be a promising therapeutic strategy for the treatment of bladder diseases and conditions characterized by inflammation, such as interstitial cystitis.

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  • [Copyright] Copyright © 2014 Elsevier B.V. All rights reserved.
  • (PMID = 24561047.001).
  • [ISSN] 1879-0712
  • [Journal-full-title] European journal of pharmacology
  • [ISO-abbreviation] Eur. J. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; ACEA (PubChem CID: 4273744) / AM630 (PubChem CID: 4302963) / Acetylcholine (PubChem CID: 6060) / Intestitial cystitis / Isolated bladder assay / JWH015 / JWH015 (PubChem CID: 5311066) / Leukocytes infiltration / Mast cells / Myeloperoxidase activity
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46. |||....... 35%  Mc Laughlin D, Puri P: Familial megacystis microcolon intestinal hypoperistalsis syndrome: a systematic review. Pediatr Surg Int; 2013 Sep;29(9):947-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare and severe disorder of functional obstruction affecting bladder and bowel, usually diagnosed in the neonatal period.
  • Four further index patients with a confirmed diagnosis and also one of the sibling pairs were reported to have a sibling in which MMIHS was probable.
  • [MeSH-major] Abnormalities, Multiple / diagnosis. Abnormalities, Multiple / genetics. Colon / abnormalities. Intestinal Pseudo-Obstruction / diagnosis. Intestinal Pseudo-Obstruction / genetics. Urinary Bladder / abnormalities

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  • (PMID = 23955298.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] Megacystis microcolon intestinal hypoperistalsis syndrome
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47. |||....... 35%  Sitsapesan H, Green AL, Aziz TZ, Pereira EA: The periaqueductal grey area and control of blood pressure in neurodegeneration. Clin Auton Res; 2013 Aug;23(4):215-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present the case of an initially hypertensive man who developed a presumed neurodegenerative disorder over a decade, characterised by progressive right-sided chronic pain, extra-pyramidal symptoms and autonomic dysfunction including postural hypotension, sleep apnoea, and bladder instability.
  • This may imply a functional involvement of the PAG/PVG in the neurodegenerative process.

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  • (PMID = 23812562.001).
  • [ISSN] 1619-1560
  • [Journal-full-title] Clinical autonomic research : official journal of the Clinical Autonomic Research Society
  • [ISO-abbreviation] Clin. Auton. Res.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / /
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antiparkinson Agents
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48. |||....... 35%  Ding D, Fullard M, Jarrell HS, Jones DE: Intramedullary spinal cord metastasis from salivary ductal carcinoma of the parotid gland mimicking transverse myelitis in a patient with radiologically isolated syndrome. J Neurol Sci; 2014 Jan 15;336(1-2):265-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Due to similar timing of clinical progression and imaging characteristics, these lesions may be misdiagnosed as transverse myelitis, an inflammatory disorder of the spinal cord that may be idiopathic or secondary to other diseases including infections, connective tissue disorders, nutritional deficiencies, and demyelinating disorders.
  • The patient initially presented with mid-thoracic dermatomal numbness, bilateral lower extremity weakness, and neurogenic bladder.
  • The goals of surgery are spinal cord decompression, functional preservation, and tissue diagnosis.
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Humans. Male. Syndrome. Thoracic Vertebrae / radiography. Thoracic Vertebrae / surgery

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  • [Copyright] © 2013.
  • (PMID = 24199731.001).
  • [ISSN] 1878-5883
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Multiple sclerosis / Neoplasm metastasis / Parotid neoplasms / Radiologically isolated syndrome / Spinal cord neoplasms / Transverse myelitis
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49. |||....... 35%  Hsi RS, Dearn J, Dean M, Zamora DA, Kanal KM, Harper JD, Merguerian PA: Effective and organ specific radiation doses from videourodynamics in children. J Urol; 2013 Oct;190(4):1364-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diagnoses included neurogenic bladder (73%), anatomical abnormality (14%) and functional/nonneurogenic disorder (13%).
  • On univariate analysis age, height, weight, body mass index, bladder capacity and fluoroscopy time were associated with effective dose.
  • On multivariate adjusted analysis, body mass index, bladder capacity and fluoroscopy time were independently associated with effective dose.
  • CONCLUSIONS: The average effective dose of ionizing radiation from videourodynamics was less compared to voiding cystourethrogram dose reported in the literature.
  • Greater fluoroscopy time, body mass index and bladder capacity are independently associated with higher dosing.

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  • [Copyright] Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
  • [CommentIn] J Urol. 2013 Oct;190(4):1369-70 [23871524.001]
  • (PMID = 23707437.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; AK / BMI / ED / ESD / air kerma / body mass index / effective dose / entrance skin dose / fluoroscopy / pediatrics / radiation dosage / urodynamics
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50. |||....... 35%  Reichler IM, Hubler M: Urinary incontinence in the bitch: an update. Reprod Domest Anim; 2014 Jun;49 Suppl 2:75-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Urinary incontinence (UI), defined as the involuntary loss of urine during the filling phase of the bladder (Abrams et al. 2002), is a commonly seen problem in veterinary practice.
  • Urinary sphincter mechanism incompetence (USMI) after spaying is the most common micturition disorder, and its medical treatment is normally successful, even though the underlying pathophysiological mechanism is not fully understood.
  • Hormonal changes inducing structural and functional alterations in the bladder, as well as in the urethra composition, are discussed.
  • Specialized clinical assessments may provide an aetiological diagnosis, and this could serve as a basis for discussing further treatment options.
  • Equivocal results of quantitative cultures of urine samples obtained during midstream voiding or by catheterization require repeat collection by cystocentesis (Comer and Ling 1981).

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  • [Copyright] © 2014 Blackwell Verlag GmbH.
  • (PMID = 24947864.001).
  • [ISSN] 1439-0531
  • [Journal-full-title] Reproduction in domestic animals = Zuchthygiene
  • [ISO-abbreviation] Reprod. Domest. Anim.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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2. Definitions


3. Related RMF webpages
1. functional disorder of bladder disorder
2. functional disorder of intestine disorder
3. disorder functional gastrointestinal
4. functional diarrhea disorder
5. respiratory disorder functional impaired
6. disease or functional heart disorder
7. contracted bladder disorder
8. bladder trabeculation disorder
9. hypertrophy of bladder disorder
10. bladder disorder neurogenic
11. bladder necrosis disorder
12. injury of bladder disorder
13. rupture of bladder disorder
14. congenital anomaly of the bladder disorder
15. low compliance bladder disorder
16. diverticulum of bladder nos disorder
17. congenital absence of bladder disorder
18. detrusor hyperreflexia of bladder disorder
19. fibrosis of urinary bladder disorder
20. other disorders of bladder disorder
21. bladder papilloma nos disorder
22. carcinoma in situ of bladder disorder
23. malignant tumor of vault of bladder disorder
24. malignant neoplasm of lateral wall of urinary bladder disorder
25. bladder neurogenic cord bladder
26. bladder cord bladder
27. bladder contracted bladder
28. hemorrhage functional
29. quadriplegia functional
30. deafness functional
31. functional hypoglycemia
32. anesthesia functional
33. functional paraplegia
34. functional bleedings
35. functional laterality
36. hemorrhage functional disturbance
37. functional assessment nos
38. kidney functional disturbance
39. kidney disease functional
40. colonic disease functional
41. functional heart bruit
42. somatic functional disturbance
43. hearing loss functional
44. functional residual capacity
45. orthodontic appliances functional
46. colonic diseases functional
47. physiological functional disturbance
48. gland functional disturbance
49. hepatic functional disturbance
50. heart functional disturbance

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