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1. Biomedical articles (top 27; 2009 to 2014)
1. |||||..... 50%  Staecker H, Praetorius M, Brough DE: Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research. Hear Res; 2011 Jun;276(1-2):44-51
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  • [Title] Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research.
  • [MeSH-major] Genetic Therapy. Labyrinth Diseases / therapy

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  • [Copyright] Copyright © 2011 Elsevier B.V. All rights reserved.
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  • (PMID = 21251965.001).
  • [ISSN] 1878-5891
  • [Journal-full-title] Hearing research
  • [ISO-abbreviation] Hear. Res.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC008424-01A2
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors
  • [Other-IDs] NLM/ NIHMS266628; NLM/ PMC3109124
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2. |||....... 35%  Kao CL, Hsieh WL, Wang SJ, Chen SJ, Wei SH, Chan RC: Efficacy of a computerized sensor system for evaluation and training of dizzy patients. Sensors (Basel); 2010;10(8):7602-20
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  • Patients with vestibular hypofunction often experience dizziness and unsteadiness while moving their heads.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Head Movements. Humans. Male. Middle Aged. Postural Balance. Quality of Life. Questionnaires. Vestibular Diseases / diagnosis. Vestibular Diseases / rehabilitation. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22163617.001).
  • [ISSN] 1424-8220
  • [Journal-full-title] Sensors (Basel, Switzerland)
  • [ISO-abbreviation] Sensors (Basel)
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3231177
  • [Keywords] NOTNLM ; balance / center of pressure / dizziness / dynamic visual acuity / vestibular hypofunction
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3. |||....... 32%  Thompson LA, Haburcakova C, Gong W, Lee DJ, Wall C 3rd, Merfeld DM, Lewis RF: Responses evoked by a vestibular implant providing chronic stimulation. J Vestib Res; 2012;22(1):11-5
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  • These results suggest that not only can the implementation of a vestibular prosthesis provide partial restitution of VOR but may also improve perception and posture in the presence of bilateral vestibular hypofunction (BVH).
  • [MeSH-major] Evoked Potentials, Auditory / physiology. Prostheses and Implants. Vestibular Diseases / physiopathology. Vestibular Diseases / therapy. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22699148.001).
  • [ISSN] 1878-6464
  • [Journal-full-title] Journal of vestibular research : equilibrium & orientation
  • [ISO-abbreviation] J Vestib Res
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / DC008167; United States / NIDCD NIH HHS / DC / DC3066; United States / NIDCD NIH HHS / DC / DC83962; United States / NIDCD NIH HHS / DC / R01 DC008362; United States / NIDCD NIH HHS / DC / T32 DC000038
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS579264; NLM/ PMC4041130
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4. |||||||||. 104%  Schönfeld U, Helling K, Clarke AH: Evidence of unilateral isolated utricular hypofunction. Acta Otolaryngol; 2010 Jun;130(6):702-7
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  • [Title] Evidence of unilateral isolated utricular hypofunction.
  • CONCLUSIONS: The findings demonstrate that an enduring unilateral utricular dysfunction, possibly together with canal hypofunction, can occur after labyrinthine disease or injury.
  • OBJECTIVES: To determine the incidence of unilateral utricular hypofunction.
  • [MeSH-major] Functional Laterality / physiology. Labyrinth Diseases / diagnosis. Meniere Disease / diagnosis. Saccule and Utricle / physiopathology. Vestibular Function Tests

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  • (PMID = 20082563.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. |||....... 31%  Schubert MC, Migliaccio AA, Ng TW, Shaikh AG, Zee DS: The under-compensatory roll aVOR does not affect dynamic visual acuity. J Assoc Res Otolaryngol; 2012 Aug;13(4):517-25
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  • We used the scleral search coil technique to measure eye and head velocity during passive DVA testing in yaw, roll, and pitch head impulses in healthy controls and patients with unilateral vestibular hypofunction (UVH).
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Case-Control Studies. Female. Fovea Centralis / physiology. Humans. Male. Middle Aged. Time Factors. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22526736.001).
  • [ISSN] 1438-7573
  • [Journal-full-title] Journal of the Association for Research in Otolaryngology : JARO
  • [ISO-abbreviation] J. Assoc. Res. Otolaryngol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY01849; United States / PHS HHS / / K23-007926
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3387313
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6. |||....... 31%  Melvin TA, Della Santina CC, Carey JP, Migliaccio AA: The effects of cochlear implantation on vestibular function. Otol Neurotol; 2009 Jan;30(1):87-94
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  • OBJECTIVE: Determine the risk posed by cochlear implantation (CI) to the labyrinth.
  • RESULTS: All 36 ears were tested using qHIT before CI, and 28 ears were tested 4 to 8 weeks after CI. qHIT showed that 1 of 28 ears had reduced function. cHIT was 44% sensitive and 94% specific for identification of severe-to-profound vestibular hypofunction confirmed by qHIT.
  • Thus, it is important to educate CI candidates regarding possible risk to balance function, particularly when CI of an "only balancing ear" is contemplated. cHIT is useful for detecting severe high-frequency vestibular hypofunction and should be part of the pre-CI physical examination.

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  • (PMID = 19108038.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / 5T32DC002717; United States / NIDCD NIH HHS / DC / K08 DC006216; United States / NIDCD NIH HHS / DC / K08 DC006216-05; United States / NIDCD NIH HHS / DC / K08DC006216; United States / NIDCD NIH HHS / DC / R01 DC009255; United States / NIDCD NIH HHS / DC / R01 DC009255-01A1
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS134771; NLM/ PMC2767271
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7. |||....... 31%  Migliaccio AA, Schubert MC: Unilateral adaptation of the human angular vestibulo-ocular reflex. J Assoc Res Otolaryngol; 2013 Feb;14(1):29-36
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  • However, a large portion of vestibular patients have unilateral vestibular hypofunction, and training that raises their VOR response during rotations to both the ipsilesional and contralesional side is not usually ideal.
  • [MeSH-minor] Adult. Eye Movements / physiology. Humans. Middle Aged. Rotation. Time Factors. Vestibule, Labyrinth / physiology

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  • (PMID = 23180230.001).
  • [ISSN] 1438-7573
  • [Journal-full-title] Journal of the Association for Research in Otolaryngology : JARO
  • [ISO-abbreviation] J. Assoc. Res. Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3540281
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8. |||||||||. 86%  Chou CH, Wang SJ, Young YH: Feasibility of the simultaneous ocular and cervical vestibular-evoked myogenic potentials in unilateral vestibular hypofunction. Clin Neurophysiol; 2009 Sep;120(9):1699-705
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Feasibility of the simultaneous ocular and cervical vestibular-evoked myogenic potentials in unilateral vestibular hypofunction.
  • OBJECTIVE: This study compared the results of combined and individual ocular vestibular-evoked myogenic potential (oVEMP) and cervical VEMP (cVEMP) tests in healthy subjects and patients with unilateral vestibular hypofunction to confirm the effectiveness of the combined oVEMP and cVEMP test.
  • METHODS: Twenty healthy volunteers and 12 patients with unilateral vestibular hypofunction underwent individual oVEMP and cVEMP tests in a random order, and combined oVEMP and cVEMP test on another day.
  • In 12 patients with unilateral vestibular hypofunction, differences in abnormal percentages of oVEMPs or cVEMPs were non-significant.
  • Additionally, the characteristic parameters of oVEMP/cVEMP among ears of healthy subjects, good and pathological ears of patients with unilateral vestibular hypofunction did not differ significantly, regardless of whether the individual or combined mode was used.
  • CONCLUSIONS: The combined oVEMP and cVEMP test generates similar information to that obtained by individual mode, regardless of whether subjects are healthy or have unilateral vestibular hypofunction.
  • [MeSH-major] Cervical Vertebrae / physiology. Electromyography / methods. Ocular Physiological Phenomena. Reflex, Vestibulo-Ocular / physiology. Vestibular Diseases / physiopathology. Vestibule, Labyrinth / physiopathology

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  • (PMID = 19683469.001).
  • [ISSN] 1872-8952
  • [Journal-full-title] Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
  • [ISO-abbreviation] Clin Neurophysiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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9. ||||||||.. 81%  Dannenbaum E, Paquet N, Chilingaryan G, Fung J: Clinical evaluation of dynamic visual acuity in subjects with unilateral vestibular hypofunction. Otol Neurotol; 2009 Apr;30(3):368-72
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  • [Title] Clinical evaluation of dynamic visual acuity in subjects with unilateral vestibular hypofunction.
  • 1) to examine the effect of frequency of head motion on the clinical dynamic visual acuity (DVA) score in subjects with unilateral vestibular hypofunction (UVH);.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Caloric Tests. Female. Head Movements. Humans. Male. Middle Aged. Paresis / complications. Vestibular Function Tests. Vestibule, Labyrinth / physiology. Vestibule, Labyrinth / surgery. Vision Tests

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  • (PMID = 19318888.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. ||||||||.. 77%  Agrawal Y, Migliaccio AA, Minor LB, Carey JP: Vestibular hypofunction in the initial postoperative period after surgical treatment of superior semicircular canal dehiscence. Otol Neurotol; 2009 Jun;30(4):502-6
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  • [Title] Vestibular hypofunction in the initial postoperative period after surgical treatment of superior semicircular canal dehiscence.
  • OBJECTIVES:. 1) Determine the prevalence of vestibular hypofunction in the immediate postoperative period after surgical treatment of superior semicircular canal dehiscence syndrome.
  • 2) Evaluate whether dehiscence length is associated with risk of postoperative vestibular hypofunction.
  • 3) Compare the prevalences of immediate and late postoperative vestibular hypofunction.
  • Bedside horizontal head thrust testing (hHTT) was administered between postoperative days 1 to 7 to diagnose immediate postoperative vestibular hypofunction.
  • Both hHTT and quantitative vestibulo-ocular reflex testing were administered 6 to 29 weeks postoperatively to detect late vestibular hypofunction.
  • MAIN OUTCOME MEASURES: Dehiscence length and hypofunction in response to hHTT.
  • RESULTS: Thirty-eight percent of the subjects (95% confidence interval, 25-54) had hypofunction in response to hHTT within 1 week after surgery.
  • Mean dehiscence lengths were 4.9 (range, 2.0-10.5 mm) and 3.4 mm (range, 1.0-5.5 mm) in subjects with and without postoperative hypofunction, respectively (p = 0.0018).
  • Each 1-mm increase in dehiscence length increased the odds of immediate postoperative hypofunction 2.6-fold (95% confidence interval, 1.3-5.1).
  • The prevalence of vestibular hypofunction was significantly higher in the early compared with the late postoperative period.
  • CONCLUSION: Immediate postoperative vestibular hypofunction is common, particularly with larger dehiscences.
  • This hypofunction may typically resolve, given that the prevalence of vestibular hypofunction 6 weeks postoperatively is low.
  • [MeSH-major] Postoperative Complications. Semicircular Canals. Vestibular Diseases / physiopathology. Vestibule, Labyrinth / physiopathology

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  • (PMID = 19339908.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. |||||||... 73%  Porciuncula F, Johnson CC, Glickman LB: The effect of vestibular rehabilitation on adults with bilateral vestibular hypofunction: a systematic review. J Vestib Res; 2012;22(5-6):283-98
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  • [Title] The effect of vestibular rehabilitation on adults with bilateral vestibular hypofunction: a systematic review.
  • PURPOSE: Adults with bilateral vestibular hypofunction (BVH) experience significant disability.
  • [MeSH-major] Vestibular Diseases / rehabilitation. Vestibule, Labyrinth / physiology

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  • (PMID = 23302709.001).
  • [ISSN] 1878-6464
  • [Journal-full-title] Journal of vestibular research : equilibrium & orientation
  • [ISO-abbreviation] J Vestib Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
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12. |||....... 33%  Lee YJ, Shin JE, Park MS, Kim JM, Na BR, Kim CH, Park HJ: Comprehensive analysis of head-shaking nystagmus in patients with vestibular neuritis. Audiol Neurootol; 2012;17(4):228-34
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  • Overall, HSN showed high abnormal rates (94 and 89%) during the acute and follow-up stages and could detect vestibular hypofunction even when canal paresis (CP) had normalized at follow-up.
  • These findings indicate that the HSN test is a sensitive detector of vestibular hypofunction upon 2-Hz head rotation.
  • HSN may reveal previous vestibular hypofunction in the 2-Hz frequency range even at follow-up, when caloric responses detecting vestibular hypofunction in the low-frequency range had normalized.
  • The two tests utilize different mechanisms to assess vestibular hypofunction and are complementary.
  • Monophasic HSN, which is commonly found in dizzy patients, indicates less severe vestibular hypofunction than biphasic HSN in the 2-Hz frequency range, and the caloric tests can provide further information about the side and presence of vestibular hypofunction at lower frequencies.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Vestibular Function Tests. Vestibule, Labyrinth / physiopathology

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  • [Copyright] Copyright © 2012 S. Karger AG, Basel.
  • (PMID = 22487934.001).
  • [ISSN] 1421-9700
  • [Journal-full-title] Audiology & neuro-otology
  • [ISO-abbreviation] Audiol. Neurootol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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13. |||....... 32%  Ma Y, Ou Y, Chen L, Zheng Y: [Vestibular testing abnormalities in individuals with motion sickness]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Aug;23(16):728-30
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  • RESULT: Two groups' Graybiel score (12.67 +/- 11.78 vs 2.10 +/- 6.23; rank test P<0.05), caloric test labyrinth value [(19.02 +/- 8.59) degrees/s vs (13.58 +/- 5.25) degrees/s; t test P<0.05], caloric test labyrinth value of three patients in motion sickness group exceeded 75 degrees/s.
  • Generally evaluating CPT, there was only 2 proprioceptive hypofunction, 3 visual hypofunction, and no vestibular hypofunction, but none hypofunction in control group.
  • In posturography, a large number of motion sickness patients are central type but no vestibular hypofunction, but it is hard to keep balance when stimulating vestibulum.

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  • (PMID = 20041604.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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14. |||....... 32%  Badaracco C, Labini FS, Meli A, Tufarelli D: Oscillopsia in labyrinthine defective patients: comparison of objective and subjective measures. Am J Otolaryngol; 2010 Nov-Dec;31(6):399-403
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  • SUBJECTS: Sixty-five subjects: 35 controls (12 men and 23 women; mean age, 50.77 ± 13.39 years) and 30 patients with chronic dizziness: 18 with unilateral vestibular hypofunction (7 men and 11 women; mean age, 55.50 ± 12.72 years) and 12 with bilateral hypofunction (7 men and 5 women; mean age, 57.25 ± 9.18 years).
  • Moreover, the DVA test in down direction differentiates patients with unilateral vestibular hypofunction and with bilateral vestibular hypofunction.
  • [MeSH-major] Illusions. Labyrinth Diseases / physiopathology

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20015789.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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15. |||....... 32%  Zamyslowska-Szmytke E, Sliwinska-Kowalska M: Vestibular and balance findings in nonsymptomatic workers exposed to styrene and dichloromethane. Int J Audiol; 2011 Nov;50(11):815-22
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  • Lower vestibular reactivity may suggest that bilateral vestibular hypofunction might also be the possible consequence of solvent exposure.
  • [MeSH-major] Methylene Chloride / adverse effects. Occupational Diseases / chemically induced. Postural Balance / drug effects. Sensation Disorders / chemically induced. Solvents / adverse effects. Styrene / adverse effects. Vestibular Diseases / chemically induced. Vestibule, Labyrinth / drug effects

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  • HSDB. structure - STYRENE.
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  • (PMID = 21929376.001).
  • [ISSN] 1708-8186
  • [Journal-full-title] International journal of audiology
  • [ISO-abbreviation] Int J Audiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Solvents; 44LJ2U959V / Styrene; 588X2YUY0A / Methylene Chloride
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16. |||....... 32%  Wolter NE, Cushing SL, Das-Purkayastha PK, Papsin BC: Non-accidental caustic ear injury: two cases of profound cochleo-vestibular loss and facial nerve injury. Int J Pediatr Otorhinolaryngol; 2012 Jan;76(1):145-8
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  • This case series represents the first report of non-accidental caustic injury to previously normal ears resulting in profound sensorineural hearing loss, vertigo with horizontal canal hypofunction and in one patient a severe facial nerve paralysis.
  • [MeSH-minor] Child. Cochlea / injuries. Cochlea / radiography. Combined Modality Therapy. Emergency Service, Hospital. Follow-Up Studies. Humans. Injury Severity Score. Risk Assessment. Time Factors. Tomography, X-Ray Computed / methods. Tympanic Membrane / injuries. Tympanic Membrane / surgery. Vertigo / chemically induced. Vertigo / diagnosis. Vertigo / therapy. Vestibule, Labyrinth / injuries. Vestibule, Labyrinth / surgery

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  • [Copyright] Crown Copyright © 2011. Published by Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 22018928.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Caustics
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17. |||....... 32%  Scherer MR, Burrows H, Pinto R, Littlefield P, French LM, Tarbett AK, Schubert MC: Evidence of central and peripheral vestibular pathology in blast-related traumatic brain injury. Otol Neurotol; 2011 Jun;32(4):571-80
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  • CONCLUSION: Vestibular function testing confirms a greater incidence of peripheral vestibular hypofunction in dizzy service members with blast-related TBI relative to those who are asymptomatic.
  • [MeSH-minor] Adult. Female. Humans. Iraq War, 2003-2011. Male. Middle Aged. Military Personnel. Oculomotor Nerve / physiopathology. Prospective Studies. Vestibular Function Tests. Vestibule, Labyrinth / physiopathology

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  • (PMID = 21358450.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. |||....... 32%  Nabi S, Parnes LS: Bilateral Ménière's disease. Curr Opin Otolaryngol Head Neck Surg; 2009 Oct;17(5):356-62
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  • Ablative treatments are relatively contraindicated due to the risks of bilateral vestibular and cochlear hypofunction.
  • [MeSH-minor] Drainage. Endolymphatic Duct / surgery. Evoked Potentials, Auditory. Glucocorticoids / therapeutic use. Humans. Magnetic Resonance Imaging. Treatment Outcome. Vertigo / drug therapy. Vestibule, Labyrinth / physiopathology

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  • (PMID = 19617826.001).
  • [ISSN] 1531-6998
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucocorticoids
  • [Number-of-references] 66
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19. |||....... 31%  Nakajima Y, Kaga K, Takekoshi H, Sakuraba K: Evaluation of vestibular and dynamic visual acuity in adults with congenital deafness. Percept Mot Skills; 2012 Oct;115(2):503-11
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  • The caloric test indicated hypofunction of the lateral semicircular canal function in 5 of the 19 athletes with deafness.
  • [MeSH-major] Deafness / congenital. Deafness / physiopathology. Vestibule, Labyrinth / physiopathology. Visual Acuity


20. |||....... 31%  Cushing SL, Papsin BC, Rutka JA, James AL, Blaser SL, Gordon KA: Vestibular end-organ and balance deficits after meningitis and cochlear implantation in children correlate poorly with functional outcome. Otol Neurotol; 2009 Jun;30(4):488-95
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Horizontal canal function in response to caloric stimulation was abnormal in all children, with 5 of 8 demonstrating bilateral areflexia and 3 of 8 having asymmetric hypofunction with better function on the implanted side.
  • [MeSH-major] Cochlear Implantation. Hearing Loss, Sensorineural / physiopathology. Meningitis / complications. Postural Balance. Vestibule, Labyrinth / physiopathology

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  • (PMID = 19395989.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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21. |||....... 31%  de Heer AM, Huygen PL, Collin RW, Kremer H, Cremers CW: Mild and variable audiometric and vestibular features in a third DFNA15 family with a novel mutation in POU4F3. Ann Otol Rhinol Laryngol; 2009 Apr;118(4):313-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vestibular function tests revealed hypofunction of the vestibular labyrinth in 2 mutation carriers (not statistically significant).

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  • (PMID = 19462854.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / POU4F3 protein, human; 0 / Transcription Factor Brn-3C
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22. |||....... 31%  Lempert T: [Vestibular migraine]. Nervenarzt; 2009 Aug;80(8):895-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • During acute attacks there may be central spontaneous or positional nystagmus and, less commonly, unilateral vestibular hypofunction.
  • The pathogenesis of VM is uncertain but migraine mechanisms may interfere with the vestibular system at the level of the labyrinth, brainstem and cerebral cortex.

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  • (PMID = 19629427.001).
  • [ISSN] 1433-0407
  • [Journal-full-title] Der Nervenarzt
  • [ISO-abbreviation] Nervenarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 24
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23. |||....... 31%  Lempert T, Neuhauser H, Daroff RB: Vertigo as a symptom of migraine. Ann N Y Acad Sci; 2009 May;1164:242-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • During acute attacks, there may be central spontaneous or positional nystagmus and, less commonly, unilateral vestibular hypofunction.
  • The pathogenesis of VM is uncertain, but migraine mechanisms may interfere with the vestibular system at the labyrinth, brainstem, and cerebral cortex.

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  • (PMID = 19645907.001).
  • [ISSN] 1749-6632
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. ||........ 23%  Andrade IV, Santos-Perez S, Diz PG, Caballero TL, Soto-Varela A: Correlation between bithermal caloric test results and vestibular evoked myogenic potentials (VEMPs) in normal subjects. Eur Arch Otorhinolaryngol; 2013 May;270(5):1623-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • From the caloric test, we assessed the presence of possible vestibular hypofunction, whether there was directional preponderance and reflectivity of each ear (all based on both slow phase velocity and nystagmus frequency).
  • We compared the reflectivity, hypofunction and directional preponderance of the caloric tests with the corrected amplitudes and amplitude asymmetries of the VEMPs.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Audiometry, Pure-Tone. Caloric Tests. Female. Humans. Male. Middle Aged. Prospective Studies. Vestibule, Labyrinth / physiology. Young Adult

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  • (PMID = 22948860.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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25. ||........ 23%  Ward BK, Roberts DC, Della Santina CC, Carey JP, Zee DS: Magnetic vestibular stimulation in subjects with unilateral labyrinthine disorders. Front Neurol; 2014;5:28
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We recorded eye movements in the static magnetic field of a 7 T MRI machine in nine individuals with unilateral labyrinthine hypofunction, as determined by head impulse testing and vestibular-evoked myogenic potentials (VEMP).
  • Right unilateral vestibular hypofunction (UVH) subjects developed slow-phase-up nystagmus and left UVH subjects, slow-phase-down nystagmus.
  • These findings provide compelling support for the hypothesis that MVS is a result of a Lorentz force and suggest that the function of individual structures within the labyrinth can be assessed with Mvs. As a novel method of comfortable and sustained labyrinthine stimulation, MVS can provide new insights into vestibular physiology and pathophysiology.

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  • (PMID = 24659983.001).
  • [ISSN] 1664-2295
  • [Journal-full-title] Frontiers in neurology
  • [ISO-abbreviation] Front Neurol
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / P30 DC005211
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3952138
  • [Keywords] NOTNLM ; Lorentz / magnetic / magneto-hydrodynamics / semicircular canals / vestibular
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26. ||........ 23%  Viana LM, Salviz M, Rauch SD, Nadol JB: Otopathology in idiopathic Dandy's syndrome. Otol Neurotol; 2013 Aug;34(6):1099-103
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Dandy's syndrome, or bilateral vestibular hypofunction and oscillopsia, may cause chronic disequilibrium aggravated by head movement or in the presence of reduced light.
  • RESULTS: In this case, the otopathology demonstrated vestibular atelectasis of the membranous labyrinth of the superior, lateral, and posterior semicircular canals but not the utricle or saccule bilaterally.

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  • [Cites] Ann Otol Rhinol Laryngol Suppl. 2000 May;181:14-9 [10821230.001]
  • [Cites] Am J Otol. 1980 Jan;1(3):151-6 [7457577.001]
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  • (PMID = 23542133.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / U24 DC011943
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS433266; NLM/ PMC3701038
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27. ||........ 22%  Wenzel A, Ward BK, Schubert MC, Kheradmand A, Zee DS, Mantokoudis G, Carey JP: Patients with vestibular loss, tullio phenomenon, and pressure-induced nystagmus: vestibular atelectasis? Otol Neurotol; 2014 Jun;35(5):866-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To propose an etiology for a syndrome of bilateral vestibular hypofunction and sound and/or pressure-evoked eye movements with normal hearing thresholds.
  • PATIENTS: Four patients with bilateral vestibular hypofunction, sound and/or pressure-evoked nystagmus and normal hearing thresholds were identified over a 3-year period.
  • RESULTS: We identified 4 patients with a combination of bilateral vestibular hypofunction and sound and/or pressure-induced eye movements, normal-hearing thresholds and no evidence for any other vestibular disorder.
  • CONCLUSION: We suggest that this unique combination of symptoms should be considered as the clinical presentation of vestibular atelectasis, which has been previously described histologically as collapse of the endolymph-containing portions of the labyrinth.

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  • (PMID = 24770400.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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