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1. Biomedical articles (top 19; 2010 to 2015)
1. |||||..... 50%  Staecker H, Praetorius M, Brough DE: Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research. Hear Res; 2011 Jun;276(1-2):44-51
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  • [Title] Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research.
  • [MeSH-major] Genetic Therapy. Labyrinth Diseases / therapy

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  • [Copyright] Copyright © 2011 Elsevier B.V. All rights reserved.
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  • (PMID = 21251965.001).
  • [ISSN] 1878-5891
  • [Journal-full-title] Hearing research
  • [ISO-abbreviation] Hear. Res.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC008424-01A2
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors
  • [Other-IDs] NLM/ NIHMS266628; NLM/ PMC3109124
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2. |||....... 34%  Kao CL, Hsieh WL, Wang SJ, Chen SJ, Wei SH, Chan RC: Efficacy of a computerized sensor system for evaluation and training of dizzy patients. Sensors (Basel); 2010;10(8):7602-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with vestibular hypofunction often experience dizziness and unsteadiness while moving their heads.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Head Movements. Humans. Male. Middle Aged. Postural Balance. Quality of Life. Questionnaires. Vestibular Diseases / diagnosis. Vestibular Diseases / rehabilitation. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22163617.001).
  • [ISSN] 1424-8220
  • [Journal-full-title] Sensors (Basel, Switzerland)
  • [ISO-abbreviation] Sensors (Basel)
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3231177
  • [Keywords] NOTNLM ; balance / center of pressure / dizziness / dynamic visual acuity / vestibular hypofunction
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3. |||....... 31%  Ward BK, Roberts DC, Della Santina CC, Carey JP, Zee DS: Magnetic vestibular stimulation in subjects with unilateral labyrinthine disorders. Front Neurol; 2014;5:28
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  • We recorded eye movements in the static magnetic field of a 7 T MRI machine in nine individuals with unilateral labyrinthine hypofunction, as determined by head impulse testing and vestibular-evoked myogenic potentials (VEMP).
  • Right unilateral vestibular hypofunction (UVH) subjects developed slow-phase-up nystagmus and left UVH subjects, slow-phase-down nystagmus.
  • These findings provide compelling support for the hypothesis that MVS is a result of a Lorentz force and suggest that the function of individual structures within the labyrinth can be assessed with Mvs. As a novel method of comfortable and sustained labyrinthine stimulation, MVS can provide new insights into vestibular physiology and pathophysiology.

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  • (PMID = 24659983.001).
  • [ISSN] 1664-2295
  • [Journal-full-title] Frontiers in neurology
  • [ISO-abbreviation] Front Neurol
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / P30 DC005211
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3952138
  • [Keywords] NOTNLM ; Lorentz / magnetic / magneto-hydrodynamics / semicircular canals / vestibular
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4. |||....... 31%  Thompson LA, Haburcakova C, Gong W, Lee DJ, Wall C 3rd, Merfeld DM, Lewis RF: Responses evoked by a vestibular implant providing chronic stimulation. J Vestib Res; 2012;22(1):11-5
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  • These results suggest that not only can the implementation of a vestibular prosthesis provide partial restitution of VOR but may also improve perception and posture in the presence of bilateral vestibular hypofunction (BVH).
  • [MeSH-major] Evoked Potentials, Auditory / physiology. Prostheses and Implants. Vestibular Diseases / physiopathology. Vestibular Diseases / therapy. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22699148.001).
  • [ISSN] 1878-6464
  • [Journal-full-title] Journal of vestibular research : equilibrium & orientation
  • [ISO-abbreviation] J Vestib Res
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / DC008167; United States / NIDCD NIH HHS / DC / DC3066; United States / NIDCD NIH HHS / DC / DC83962; United States / NIDCD NIH HHS / DC / R01 DC008362; United States / NIDCD NIH HHS / DC / T32 DC000038
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS579264; NLM/ PMC4041130
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5. |||||||... 74%  Porciuncula F, Johnson CC, Glickman LB: The effect of vestibular rehabilitation on adults with bilateral vestibular hypofunction: a systematic review. J Vestib Res; 2012;22(5-6):283-98
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  • [Title] The effect of vestibular rehabilitation on adults with bilateral vestibular hypofunction: a systematic review.
  • PURPOSE: Adults with bilateral vestibular hypofunction (BVH) experience significant disability.
  • [MeSH-major] Vestibular Diseases / rehabilitation. Vestibule, Labyrinth / physiology

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  • (PMID = 23302709.001).
  • [ISSN] 1878-6464
  • [Journal-full-title] Journal of vestibular research : equilibrium & orientation
  • [ISO-abbreviation] J Vestib Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
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6. |||....... 30%  Migliaccio AA, Schubert MC: Unilateral adaptation of the human angular vestibulo-ocular reflex. J Assoc Res Otolaryngol; 2013 Feb;14(1):29-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, a large portion of vestibular patients have unilateral vestibular hypofunction, and training that raises their VOR response during rotations to both the ipsilesional and contralesional side is not usually ideal.
  • [MeSH-minor] Adult. Eye Movements / physiology. Humans. Middle Aged. Rotation. Time Factors. Vestibule, Labyrinth / physiology

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  • (PMID = 23180230.001).
  • [ISSN] 1438-7573
  • [Journal-full-title] Journal of the Association for Research in Otolaryngology : JARO
  • [ISO-abbreviation] J. Assoc. Res. Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3540281
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7. |||||||||. 107%  Schönfeld U, Helling K, Clarke AH: Evidence of unilateral isolated utricular hypofunction. Acta Otolaryngol; 2010 Jun;130(6):702-7
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  • [Title] Evidence of unilateral isolated utricular hypofunction.
  • CONCLUSIONS: The findings demonstrate that an enduring unilateral utricular dysfunction, possibly together with canal hypofunction, can occur after labyrinthine disease or injury.
  • OBJECTIVES: To determine the incidence of unilateral utricular hypofunction.
  • [MeSH-major] Functional Laterality / physiology. Labyrinth Diseases / diagnosis. Meniere Disease / diagnosis. Saccule and Utricle / physiopathology. Vestibular Function Tests

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  • (PMID = 20082563.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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8. |||....... 31%  Viana LM, Salviz M, Rauch SD, Nadol JB: Otopathology in idiopathic Dandy's syndrome. Otol Neurotol; 2013 Aug;34(6):1099-103
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  • BACKGROUND: Dandy's syndrome, or bilateral vestibular hypofunction and oscillopsia, may cause chronic disequilibrium aggravated by head movement or in the presence of reduced light.
  • RESULTS: In this case, the otopathology demonstrated vestibular atelectasis of the membranous labyrinth of the superior, lateral, and posterior semicircular canals but not the utricle or saccule bilaterally.

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  • (PMID = 23542133.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / U24 DC011943
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS433266; NLM/ PMC3701038
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9. |||....... 32%  Lee YJ, Shin JE, Park MS, Kim JM, Na BR, Kim CH, Park HJ: Comprehensive analysis of head-shaking nystagmus in patients with vestibular neuritis. Audiol Neurootol; 2012;17(4):228-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Overall, HSN showed high abnormal rates (94 and 89%) during the acute and follow-up stages and could detect vestibular hypofunction even when canal paresis (CP) had normalized at follow-up.
  • These findings indicate that the HSN test is a sensitive detector of vestibular hypofunction upon 2-Hz head rotation.
  • HSN may reveal previous vestibular hypofunction in the 2-Hz frequency range even at follow-up, when caloric responses detecting vestibular hypofunction in the low-frequency range had normalized.
  • The two tests utilize different mechanisms to assess vestibular hypofunction and are complementary.
  • Monophasic HSN, which is commonly found in dizzy patients, indicates less severe vestibular hypofunction than biphasic HSN in the 2-Hz frequency range, and the caloric tests can provide further information about the side and presence of vestibular hypofunction at lower frequencies.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Vestibular Function Tests. Vestibule, Labyrinth / physiopathology

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  • [Copyright] Copyright © 2012 S. Karger AG, Basel.
  • (PMID = 22487934.001).
  • [ISSN] 1421-9700
  • [Journal-full-title] Audiology & neuro-otology
  • [ISO-abbreviation] Audiol. Neurootol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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10. |||....... 32%  Badaracco C, Labini FS, Meli A, Tufarelli D: Oscillopsia in labyrinthine defective patients: comparison of objective and subjective measures. Am J Otolaryngol; 2010 Nov-Dec;31(6):399-403
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SUBJECTS: Sixty-five subjects: 35 controls (12 men and 23 women; mean age, 50.77 ± 13.39 years) and 30 patients with chronic dizziness: 18 with unilateral vestibular hypofunction (7 men and 11 women; mean age, 55.50 ± 12.72 years) and 12 with bilateral hypofunction (7 men and 5 women; mean age, 57.25 ± 9.18 years).
  • Moreover, the DVA test in down direction differentiates patients with unilateral vestibular hypofunction and with bilateral vestibular hypofunction.
  • [MeSH-major] Illusions. Labyrinth Diseases / physiopathology

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20015789.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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11. |||....... 32%  Wolter NE, Cushing SL, Das-Purkayastha PK, Papsin BC: Non-accidental caustic ear injury: two cases of profound cochleo-vestibular loss and facial nerve injury. Int J Pediatr Otorhinolaryngol; 2012 Jan;76(1):145-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This case series represents the first report of non-accidental caustic injury to previously normal ears resulting in profound sensorineural hearing loss, vertigo with horizontal canal hypofunction and in one patient a severe facial nerve paralysis.
  • [MeSH-minor] Child. Cochlea / injuries. Cochlea / radiography. Combined Modality Therapy. Emergency Service, Hospital. Follow-Up Studies. Humans. Injury Severity Score. Risk Assessment. Time Factors. Tomography, X-Ray Computed / methods. Tympanic Membrane / injuries. Tympanic Membrane / surgery. Vertigo / chemically induced. Vertigo / diagnosis. Vertigo / therapy. Vestibule, Labyrinth / injuries. Vestibule, Labyrinth / surgery

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  • [Copyright] Crown Copyright © 2011. Published by Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 22018928.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Caustics
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12. |||....... 31%  Shaikh AG, Miller BR, Sundararajan S, Katirji B: Gravity-dependent nystagmus and inner-ear dysfunction suggest anterior and posterior inferior cerebellar artery infarct. J Stroke Cerebrovasc Dis; 2014 Apr;23(4):788-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Examination revealed gravity-dependent nystagmus, unilateral hypoactive vestibulo-ocular reflex (VOR), and hearing loss ipsilateral to the VOR hypofunction.
  • Acute onset of unilateral hearing loss and VOR hypofunction could be the manifestation of inner-ear ischemic injury secondary to the anterior inferior cerebellar artery (AICA) compromise.
  • [MeSH-major] Labyrinth Diseases / etiology. Lateral Medullary Syndrome / complications. Nystagmus, Pathologic / etiology

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  • [Copyright] Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.
  • (PMID = 23800506.001).
  • [ISSN] 1532-8511
  • [Journal-full-title] Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
  • [ISO-abbreviation] J Stroke Cerebrovasc Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Stroke / dizziness / embolic stroke / posterior circulation / posterior fossa / vertigo
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13. |||....... 31%  Zamyslowska-Szmytke E, Sliwinska-Kowalska M: Vestibular and balance findings in nonsymptomatic workers exposed to styrene and dichloromethane. Int J Audiol; 2011 Nov;50(11):815-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lower vestibular reactivity may suggest that bilateral vestibular hypofunction might also be the possible consequence of solvent exposure.
  • [MeSH-major] Methylene Chloride / adverse effects. Occupational Diseases / chemically induced. Postural Balance / drug effects. Sensation Disorders / chemically induced. Solvents / adverse effects. Styrene / adverse effects. Vestibular Diseases / chemically induced. Vestibule, Labyrinth / drug effects

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  • (PMID = 21929376.001).
  • [ISSN] 1708-8186
  • [Journal-full-title] International journal of audiology
  • [ISO-abbreviation] Int J Audiol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Solvents; 44LJ2U959V / Styrene; 588X2YUY0A / Methylene Chloride
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14. |||....... 31%  Mostafa BE, Shafik AG, El Makhzangy AM, Taha H, Abdel Mageed HM: Evaluation of vestibular function in patients with chronic suppurative otitis media. ORL J Otorhinolaryngol Relat Spec; 2013;75(6):357-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rotatory chair abnormalities were found in 70% of the cases, caloric hypofunction was found in 61.6%, and vestibular myogenic evoked potentials were abnormal in 25%.
  • [MeSH-major] Otitis Media, Suppurative / diagnosis. Otitis Media, Suppurative / physiopathology. Semicircular Canals / physiopathology. Vestibular Function Tests / methods. Vestibule, Labyrinth / physiopathology

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  • [Copyright] © 2014 S. Karger AG, Basel.
  • (PMID = 24480873.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
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15. |||....... 31%  Nakajima Y, Kaga K, Takekoshi H, Sakuraba K: Evaluation of vestibular and dynamic visual acuity in adults with congenital deafness. Percept Mot Skills; 2012 Oct;115(2):503-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The caloric test indicated hypofunction of the lateral semicircular canal function in 5 of the 19 athletes with deafness.
  • [MeSH-major] Deafness / congenital. Deafness / physiopathology. Vestibule, Labyrinth / physiopathology. Visual Acuity


16. |||....... 31%  Wenzel A, Ward BK, Schubert MC, Kheradmand A, Zee DS, Mantokoudis G, Carey JP: Patients with vestibular loss, tullio phenomenon, and pressure-induced nystagmus: vestibular atelectasis? Otol Neurotol; 2014 Jun;35(5):866-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To propose an etiology for a syndrome of bilateral vestibular hypofunction and sound and/or pressure-evoked eye movements with normal hearing thresholds.
  • PATIENTS: Four patients with bilateral vestibular hypofunction, sound and/or pressure-evoked nystagmus and normal hearing thresholds were identified over a 3-year period.
  • RESULTS: We identified 4 patients with a combination of bilateral vestibular hypofunction and sound and/or pressure-induced eye movements, normal-hearing thresholds and no evidence for any other vestibular disorder.
  • CONCLUSION: We suggest that this unique combination of symptoms should be considered as the clinical presentation of vestibular atelectasis, which has been previously described histologically as collapse of the endolymph-containing portions of the labyrinth.

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  • (PMID = 24770400.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. |||....... 31%  Scherer MR, Burrows H, Pinto R, Littlefield P, French LM, Tarbett AK, Schubert MC: Evidence of central and peripheral vestibular pathology in blast-related traumatic brain injury. Otol Neurotol; 2011 Jun;32(4):571-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSION: Vestibular function testing confirms a greater incidence of peripheral vestibular hypofunction in dizzy service members with blast-related TBI relative to those who are asymptomatic.
  • [MeSH-minor] Adult. Female. Humans. Iraq War, 2003-2011. Male. Middle Aged. Military Personnel. Oculomotor Nerve / physiopathology. Prospective Studies. Vestibular Function Tests. Vestibule, Labyrinth / physiopathology

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  • (PMID = 21358450.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. |||....... 31%  Andrade IV, Santos-Perez S, Diz PG, Caballero TL, Soto-Varela A: Correlation between bithermal caloric test results and vestibular evoked myogenic potentials (VEMPs) in normal subjects. Eur Arch Otorhinolaryngol; 2013 May;270(5):1623-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • From the caloric test, we assessed the presence of possible vestibular hypofunction, whether there was directional preponderance and reflectivity of each ear (all based on both slow phase velocity and nystagmus frequency).
  • We compared the reflectivity, hypofunction and directional preponderance of the caloric tests with the corrected amplitudes and amplitude asymmetries of the VEMPs.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Audiometry, Pure-Tone. Caloric Tests. Female. Humans. Male. Middle Aged. Prospective Studies. Vestibule, Labyrinth / physiology. Young Adult

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  • (PMID = 22948860.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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19. |||....... 30%  Schubert MC, Migliaccio AA, Ng TW, Shaikh AG, Zee DS: The under-compensatory roll aVOR does not affect dynamic visual acuity. J Assoc Res Otolaryngol; 2012 Aug;13(4):517-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We used the scleral search coil technique to measure eye and head velocity during passive DVA testing in yaw, roll, and pitch head impulses in healthy controls and patients with unilateral vestibular hypofunction (UVH).
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Case-Control Studies. Female. Fovea Centralis / physiology. Humans. Male. Middle Aged. Time Factors. Vestibule, Labyrinth / physiopathology

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  • (PMID = 22526736.001).
  • [ISSN] 1438-7573
  • [Journal-full-title] Journal of the Association for Research in Otolaryngology : JARO
  • [ISO-abbreviation] J. Assoc. Res. Otolaryngol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY01849; United States / PHS HHS / / K23-007926
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3387313
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