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1. Biomedical articles (top 30; 2009 to 2014)
1. |||||..... 50%  Ji GY, Wang ZN, Yao F, Xu ZY: Ebstein's anomaly of the tricuspid valve with rheumatic mitral stenosis and aortic incompetence. J Heart Valve Dis; 2009 Mar;18(2):217-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ebstein's anomaly of the tricuspid valve with rheumatic mitral stenosis and aortic incompetence.
  • The case is reported of Ebstein's anomaly of the tricuspid valve with rheumatic mitral stenosis and aortic incompetence.
  • In this extremely rare clinical entity, right ventricular dysfunction and respiratory dysfunction occur due to severe mitral stenosis and tricuspid regurgitation.
  • The present case was managed with aortic and mitral valve replacement and Danielson's repair of the tricuspid valve.
  • [MeSH-major] Aortic Valve Insufficiency / etiology. Mitral Valve Stenosis / etiology. Rheumatic Heart Disease / complications. Tricuspid Valve / abnormalities
  • [MeSH-minor] Adult. Female. Heart Valve Prosthesis. Humans. Tricuspid Valve Insufficiency / complications. Tricuspid Valve Insufficiency / surgery. Ventricular Dysfunction, Right / complications. Ventricular Dysfunction, Right / surgery

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  • (PMID = 19455898.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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2. |||||..... 47%  Ahmad S, Hayat U, Naz H: Frequency of severe mitral stenosis in young female patients having pure mitral stenosis secondary to rheumatic heart disease. J Ayub Med Coll Abbottabad; 2010 Oct-Dec;22(4):19-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequency of severe mitral stenosis in young female patients having pure mitral stenosis secondary to rheumatic heart disease.
  • BACKGROUND: High morbidity and mortality due to Rheumatic heart disease (RHD) associated with females is mainly because of late diagnosis on one hand and socioeconomic reasons on the other hand.
  • The objectives of this cross-sectional descriptive study was to assess the frequency of severe mitral stenosis in woman of child bearing age, having pure mitral stenosis (MS) secondary to rheumatic heart disease.
  • Patients with associated mitral regurgitation and aortic valve disease were excluded.
  • After admission, assessment of mitral valve stenosis was done with 2D colour Doppler echocardiography.
  • RESULTS: Out of 250 consecutive patients of rheumatic carditis, 110 (44%) patients had pure mitral valve stenosis, 85 (34%) had stenosis with mitral regurgitation and 55 (22%) patients had both mitral and aortic valve problem of varying severity.
  • Among 110 patients with pure mitral valve stenosis, 48 (43.6%) had severe mitral valve stenosis.
  • Severe mitral valve gradient (MVG) and high pulmonary artery pressure (PAP) was observed in 66 (60%) and 49 (44.5%) of the patients respectively.
  • CONCLUSION: This high frequency can be linked to lack of early detection of the disease at primary level, poor management of throat infections and poor rheumatic fever prophylaxis at community level.
  • [MeSH-major] Mitral Valve Stenosis / epidemiology. Rheumatic Heart Disease / complications
  • [MeSH-minor] Adult. Cross-Sectional Studies. Female. Hemodynamics. Humans. Mitral Valve Insufficiency / epidemiology. Mitral Valve Insufficiency / ultrasonography. Ultrasonography, Doppler, Color

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  • (PMID = 22455253.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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3. |||||..... 46%  Namboodiri N, Remash K, Tharakan JA, Shajeem O, Nair K, Titus T, Ajitkumar VK, Sivasankaran S, Krishnamoorthy KM, Harikrishnan SP, Harikrishnan MS, Bijulal S: Natural history of aortic valve disease following intervention for rheumatic mitral valve disease. J Heart Valve Dis; 2009 Jan;18(1):61-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Natural history of aortic valve disease following intervention for rheumatic mitral valve disease.
  • BACKGROUND AND AIM OF THE STUDY: A significant proportion of patients who require interventions for rheumatic mitral valve (MV) disease have coexisting aortic valve (AV) disease.
  • To date, little is known of the natural history of AV disease in these patients.
  • METHODS: The details of a cohort of 200 patients (146 females, 54 males; mean age at MV intervention 30.3 +/- 9.9 years) with rheumatic heart disease were retrospectively reviewed.
  • The patients had undergone an index MV intervention (either closed or balloon mitral valvotomy) or MV replacement between 1994 and 1996, and received long-term regular follow up examinations.
  • Patients were allocated to two groups, based on whether the AV disease was absent (group I, n=98) or present (group II, n=102) at baseline.
  • The AV disease was categorized as thickening only (group IIA), isolated aortic regurgitation (AR) (group IIB), or combined aortic stenosis (AS) and AR (group IIC).
  • RESULTS: The mean follow up period was 9.3 +/- 1.07 years; during which 10 patients in group I developed new AV disease, which included AV thickening only (n=2), trivial-mild AR (n=7) and mild AS with trivial AR (n=1).
  • Group IIC included 17 patients with mild combined AV disease at baseline, except for moderate AS and moderate AR in one patient each.
  • No patient who developed new combined AV disease had lesions with severity more than mild AS or moderate AR.
  • On logistic regression analysis of the variables predisposing to progression of AV disease, such as age, gender, history of rheumatic fever (RF) and recurrence, and interval from RF episode to symptom onset, only the initial AV gradient was identified as being statistically significant (beta coefficient 0.528, SE = 0.17, p < 0.0001).
  • CONCLUSION: Patients with no or mild AV disease at the time of MV intervention rarely develop severe AV disease, and seldom require AV surgery over the long-term follow up.
  • The presence of mild AS at baseline is predictive in the minority of cases where AV disease will progress relatively more rapidly.
  • [MeSH-major] Aortic Valve Insufficiency / pathology. Aortic Valve Stenosis / pathology. Heart Valve Diseases / therapy. Mitral Valve. Rheumatic Heart Disease / therapy
  • [MeSH-minor] Adult. Catheterization. Disease Progression. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19301554.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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4. ||||...... 42%  Morgan JA, Paone G: Resection of Lambl's excrescence on the aortic valve in a patient with rheumatic mitral valve disease and a left atrial thrombus. Heart Surg Forum; 2012 Aug;15(4):E215-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Resection of Lambl's excrescence on the aortic valve in a patient with rheumatic mitral valve disease and a left atrial thrombus.
  • We report a case of a patient with severe mitral valve stenosis from rheumatic heart disease and a large left atrial thrombus who was incidentally found to have multiple LEs on her aortic valve.
  • In addition to replacing her mitral valve and removing the left atrial thrombi, we resected the LEs from her aortic valve due to their potential to cause a stroke and the relatively low associated morbidity in resecting them while keeping the aortic valve leaflets and valve function intact.
  • [MeSH-major] Heart Atria / surgery. Heart Defects, Congenital / surgery. Heart Valve Diseases / surgery. Mitral Valve Insufficiency / surgery. Rheumatic Heart Disease / surgery. Thrombosis / surgery
  • [MeSH-minor] Aged. Aortic Valve / surgery. Aortic Valve / ultrasonography. Female. Humans. Treatment Outcome

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  • (PMID = 22917827.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Aortic Valve Disease
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5. ||||...... 41%  Antonini-Canterin F, Moura LM, Enache R, Leiballi E, Pavan D, Piazza R, Popescu BA, Ginghina C, Nicolosi GL, Rajamannan NM: Effect of hydroxymethylglutaryl coenzyme-a reductase inhibitors on the long-term progression of rheumatic mitral valve disease. Circulation; 2010 May 18;121(19):2130-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of hydroxymethylglutaryl coenzyme-a reductase inhibitors on the long-term progression of rheumatic mitral valve disease.
  • BACKGROUND: At present, no medical therapy is known to affect the progression of rheumatic mitral stenosis (MS).
  • METHODS AND RESULTS: From our 20-year database, we identified all patients with rheumatic MS with > or =2 echocardiographies > or =1 year apart.
  • Exclusion criteria were previous intervention on the mitral valve, more than moderate aortic regurgitation, or symptoms at first examination.
  • The rate of decrease in mitral valve area was significantly lower in the statin group compared with the untreated group (0.027+/-0.056 versus 0.067+/-0.082 cm(2)/y; P=0.005).
  • The prevalence of fast MS progression (annual change in mitral valve area >0.08 cm(2)) was significantly lower in the statin group (P=0.008).
  • CONCLUSIONS: Our study shows a significantly slower progression of rheumatic MS in patients treated with statins.
  • These findings could have an important impact in the early medical therapy of patients with rheumatic heart disease.
  • [MeSH-major] Aortic Valve Insufficiency / drug therapy. Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use. Mitral Valve Stenosis / drug therapy. Rheumatic Heart Disease / drug therapy
  • [MeSH-minor] Aged. Databases, Factual. Disease Progression. Echocardiography. Female. Follow-Up Studies. Humans. Male. Middle Aged. Multivariate Analysis. Pulmonary Wedge Pressure. Treatment Outcome

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  • (PMID = 20439789.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL085591-01A1; United States / NHLBI NIH HHS / HL / R01 HL085591-02; United States / NHLBI NIH HHS / HL / R01 HL085591-02S1; United States / NHLBI NIH HHS / HL / R01 HL085591-03; United States / NHLBI NIH HHS / HL / R01 HL085591-04; United States / NHLBI NIH HHS / HL / R01 HL085591-05
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • [Other-IDs] NLM/ NIHMS296421; NLM/ PMC3263343
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6. ||||...... 40%  Pedrazzini GB, Faletra F, Vassalli G, Demertzis S, Moccetti T: Mitral regurgitation. Swiss Med Wkly; 2010 Jan 23;140(3-4):36-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitral regurgitation.
  • Mitral regurgitation (MR) involves systolic retrograde flow from the left ventricle into the left atrium.
  • While trivial MR is frequent in healthy subjects, moderate to severe MR constitutes the second most prevalent valve disease after aortic valve stenosis.
  • Major causes of severe MR in Western countries include degenerative valve disease (myxomatous disease, flail leaflet, annular calcification) and ischaemic heart disease, while rheumatic disease remains a major cause of MR in developing countries.
  • Mitral valve surgery is the only treatment of proven efficacy.
  • Percutaneous, catheter-based to mitral valve repair is a novel approach currently under clinical scrutiny, with encouraging preliminary results.
  • This modality may provide a valuable alternative to mitral valve surgery, especially in critically ill patients.
  • [MeSH-major] Mitral Valve / abnormalities. Mitral Valve Insufficiency

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  • (PMID = 19950042.001).
  • [ISSN] 1424-3997
  • [Journal-full-title] Swiss medical weekly
  • [ISO-abbreviation] Swiss Med Wkly
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 38
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7. ||||...... 40%  Urban M, Pirk J, Skalský I, Szárszoi O, Netuka I: [Outcomes of combined mitral valve repair surgery and aortic valve replacement in IKEM Praha]. Rozhl Chir; 2011 Feb;90(2):95-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Outcomes of combined mitral valve repair surgery and aortic valve replacement in IKEM Praha].
  • AIM OF THE STUDY: We retrospectively analyzed long-term outcome of concomitant mitral valve repair and aortic valve replacement.
  • METHODS: From 1996 to 2009 we performed mitral valve plasty with aortic valve replacement in 50 patients.
  • RESULTS: Four patients who had previously undergone aortic valve surgery were excluded from the study.
  • Aortic valve pathology was stenosis in 21 patients, regurgitation in 20 and 4 patients presented with mixed aortic disease.
  • The etiology of mitral regurgitation was rheumatic in 6, non-rheumatic in 31 and infective in 6 patients.
  • Aortic valve was replaced with mechanical prosthesis in 22 (mean age 59) and tissue prosthesis in 24 (mean age 71) patients.
  • Out of 9 patients with residual TR, 3 were operated for rheumatic and 6 for non-rheumatic mitral valve disease.
  • One patients underwent successful mitral valve replacement with mechanical prosthesis, 3 died and 5 are treated expectantly.
  • CONCLUSION: We conclude that concomitant mitral valve repair with aortic valve replacement has high hospital mortality, excellent long-term survival and low complication rate.
  • The durability of mitral valve repair in patients with rheumatic mitral valve disease is limited and replacement, rather that repair should be considered in this patient group.
  • [MeSH-major] Aortic Valve / surgery. Heart Valve Prosthesis Implantation. Mitral Valve / surgery
  • [MeSH-minor] Aged. Bioprosthesis. Endocarditis / surgery. Female. Humans. Male. Middle Aged. Mitral Valve Insufficiency / surgery. Rheumatic Heart Disease / surgery

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  • (PMID = 21638845.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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8. ||||...... 39%  Kondoh H, Sato F, Shintani H: Simultaneous treatment of pulmonary AV malformation with rheumatic heart disease. Thorac Cardiovasc Surg; 2009 Apr;57(3):174-6
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  • [Title] Simultaneous treatment of pulmonary AV malformation with rheumatic heart disease.
  • Only 13 cases of pulmonary arteriovenous malformation (PAVM) combined with rheumatic heart disease have been reported, and only 3 have been treated simultaneously by surgery.
  • We report a case of PAVM with rheumatic heart disease, in which both diseases were simultaneously treated by surgery.
  • [MeSH-major] Arteriovenous Malformations / surgery. Heart Valve Prosthesis Implantation. Pulmonary Artery / surgery. Pulmonary Veins / surgery. Rheumatic Heart Disease / surgery. Vascular Surgical Procedures
  • [MeSH-minor] Aged. Aortic Valve Insufficiency / surgery. Aortic Valve Stenosis / surgery. Cardiopulmonary Bypass. Female. Heart Valve Diseases / complications. Heart Valve Diseases / radiography. Heart Valve Diseases / surgery. Humans. Mitral Valve Stenosis / surgery. Tomography, X-Ray Computed. Treatment Outcome


9. ||||...... 38%  Shrestha NR, Pilgrim T, Karki P, Bhandari R, Basnet S, Tiwari S, Dhakal SS, Urban P: Rheumatic heart disease revisited: patterns of valvular involvement from a consecutive cohort in eastern Nepal. J Cardiovasc Med (Hagerstown); 2012 Nov;13(11):755-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rheumatic heart disease revisited: patterns of valvular involvement from a consecutive cohort in eastern Nepal.
  • BACKGROUND: The burden of rheumatic heart disease (RHD) continues to be a major contributor to morbidity and premature death in poor and developing countries.
  • Mitral regurgitation was the most common valvular lesion across all age groups irrespective of sex (n = 1321, 77.1%).
  • Female patients were significantly older as compared to male patients at the time of presentation (32.8 ± 15.2 versus 28.5 ± 15.4 years; P < 0.001) and more commonly presented with mitral stenosis as compared to male patients (62.8 versus 51.5%; P < 0.001), with a peak between the age of 30 and 49 years.
  • Conversely, aortic regurgitation was more common in men as compared to women (55.6 versus 48.9%; P = 0.007).
  • Involvement of both the mitral and the aortic valve was observed in 49.8% of the patients and was more common in men as compared to women (52.7 versus 47.8%; P = 0.047).
  • [MeSH-major] Heart Valve Diseases / ultrasonography. Rheumatic Heart Disease / ultrasonography
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Age Factors. Aortic Valve Insufficiency / epidemiology. Aortic Valve Insufficiency / ultrasonography. Aortic Valve Stenosis / epidemiology. Aortic Valve Stenosis / ultrasonography. Chi-Square Distribution. Cohort Studies. Female. Humans. Male. Middle Aged. Mitral Valve Insufficiency / epidemiology. Mitral Valve Insufficiency / ultrasonography. Mitral Valve Stenosis / epidemiology. Mitral Valve Stenosis / ultrasonography. Nepal / epidemiology. Retrospective Studies. Sex Distribution. Sex Factors. Tertiary Care Centers. Young Adult

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  • (PMID = 22914310.001).
  • [ISSN] 1558-2035
  • [Journal-full-title] Journal of cardiovascular medicine (Hagerstown, Md.)
  • [ISO-abbreviation] J Cardiovasc Med (Hagerstown)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. ||||...... 37%  Long MA, Med M: Papillary muscle rupture: an unusual complication of chordal sparing mitral valve replacement. J Card Surg; 2011 Jan;26(1):60-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary muscle rupture: an unusual complication of chordal sparing mitral valve replacement.
  • An adult patient with advanced rheumatic heart disease undergoing chordal sparing mitral valve replacement as well as aortic valve replacement is presented.
  • The ruptured head of the papillary muscle was successfully resected via an aortotomy through the aortic valve prosthesis.
  • Care to avoid excessive tension on the preserved chordae during mitral valve replacement, especially in the setting of chronic rheumatic carditis, is stressed.
  • [MeSH-major] Cardiomyopathies. Chordae Tendineae / surgery. Heart Valve Prosthesis Implantation / methods. Mitral Valve / surgery. Papillary Muscles. Postoperative Complications
  • [MeSH-minor] Aortic Valve / surgery. Aortic Valve Insufficiency / etiology. Aortic Valve Insufficiency / surgery. Chronic Disease. Female. Humans. Middle Aged. Mitral Valve Stenosis / etiology. Mitral Valve Stenosis / surgery. Rheumatic Heart Disease. Rupture, Spontaneous. Ventricular Dysfunction, Left / etiology

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  • [Copyright] © 2010 Wiley Periodicals, Inc.
  • (PMID = 21073531.001).
  • [ISSN] 1540-8191
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. ||||...... 36%  Rayamajhi A, Sharma D, Shakya U: First-episode versus recurrent acute rheumatic fever: is it different? Pediatr Int; 2009 Apr;51(2):269-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First-episode versus recurrent acute rheumatic fever: is it different?
  • BACKGROUND: Recurrent episodes of acute rheumatic fever (RF) can lead to rheumatic heart disease with considerable disability and mortality in children.
  • Patients without a previous history of RF and/or mitral stenosis (MS) and/or aortic stenosis (AS) were defined as first-episode patients, and patients with previous history of RF and/or MS and/or AS, were defined as recurrent RF patients based on the Jones criteria.
  • Arthritis occurred in a significantly higher number of first-episode patients (P = 0.047) whereas shortness of breath (SOB; P = 0.003), palpitation (P = 0.034), and aortic regurgitation (AR; P = 0.001) occurred in a significantly higher number of recurrent RF patients.
  • [MeSH-major] Heart Valve Diseases / epidemiology. Rheumatic Fever / diagnosis. Rheumatic Heart Disease / epidemiology
  • [MeSH-minor] Adolescent. Aortic Valve Insufficiency / epidemiology. Arthritis / epidemiology. Child. Child, Preschool. Cross-Sectional Studies. Heart Murmurs. Humans. Hypertension, Pulmonary / epidemiology. Mitral Valve Insufficiency / epidemiology. Mitral Valve Insufficiency / ultrasonography. Nepal / epidemiology. Recurrence. Risk Factors. Tricuspid Valve Insufficiency / epidemiology. Tricuspid Valve Insufficiency / ultrasonography

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  • (PMID = 19405931.001).
  • [ISSN] 1442-200X
  • [Journal-full-title] Pediatrics international : official journal of the Japan Pediatric Society
  • [ISO-abbreviation] Pediatr Int
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
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12. ||||...... 35%  Omay O, Ozker E, Suzer K: Glenn shunt as an alternative procedure for rheumatoid triple valve disease with tricuspid stenosis. Thorac Cardiovasc Surg; 2009 Apr;57(3):170-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Glenn shunt as an alternative procedure for rheumatoid triple valve disease with tricuspid stenosis.
  • A 41-year-old woman with rheumatoid triple valve disease was operated.
  • Mitral and aortic valves were replaced with prosthetic valves.
  • [MeSH-major] Aortic Valve Insufficiency / surgery. Cardiac Surgical Procedures / methods. Heart Valve Prosthesis Implantation. Mitral Valve Insufficiency / surgery. Rheumatic Heart Disease / surgery. Tricuspid Valve Stenosis / surgery

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  • (PMID = 19330757.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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13. |||....... 34%  Brown JW, Fiore AC, Ruzmetov M, Eltayeb O, Rodefeld MD, Turrentine MW: Evolution of mitral valve replacement in children: a 40-year experience. Ann Thorac Surg; 2012 Feb;93(2):626-33; discussion 633
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evolution of mitral valve replacement in children: a 40-year experience.
  • BACKGROUND: This report reviews our 40-year experience with pediatric mitral valve replacement (MVR) with respect to mortality, valve-related morbidity, and reoperation risk factors.
  • Etiology was congenital in 65 patients (67%), rheumatic in 27 (28%), and endocarditis in 5 (5%).
  • Regurgitation was the predominant lesion in 67 patients (69%), stenosis in 23 (24%), and mixed in 7 (7%) patients.
  • Since 2002, 5 children have undergone Ross MVR with a pulmonary autograft in 3 and an aortic homograft in 2.
  • Variables associated with mitral re-replacement were younger age, small weight, valve diameter less than 23 mm, MVR prior to 1980, and type of implanted valves (xenograft, single-leaflet disk, ball-caged, or human valves).
  • [MeSH-major] Heart Valve Prosthesis Implantation / statistics & numerical data. Mitral Valve / surgery
  • [MeSH-minor] Adolescent. Aortic Valve / surgery. Bioprosthesis. Child. Child, Preschool. Endocarditis / surgery. Female. Follow-Up Studies. Heart Defects, Congenital / surgery. Heart Transplantation / utilization. Heart Valve Prosthesis / classification. Hospital Mortality. Humans. Infant. Infant, Newborn. Male. Mitral Valve Insufficiency / surgery. Mitral Valve Stenosis / surgery. Postoperative Complications / epidemiology. Postoperative Complications / prevention & control. Pulmonary Valve / surgery. Reoperation / utilization. Retrospective Studies. Rheumatic Heart Disease / surgery. Thromboembolism / epidemiology. Thromboembolism / prevention & control. Transplantation, Heterotopic. Treatment Outcome

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  • [Copyright] Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 22153051.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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14. |||....... 34%  Yildirir A: [Valvular heart disease associated with coronary artery disease]. Anadolu Kardiyol Derg; 2009 Jul;9 Suppl 1:10-6
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  • [Title] [Valvular heart disease associated with coronary artery disease].
  • Nowadays, age-related degenerative etiologies have largely replaced the rheumatic ones and as a natural result of this etiologic change, coronary artery disease has become associated with valvular heart disease to a greater extent.
  • Degenerative aortic valve disease has an important pathophysiological similarity to atherosclerosis and is the leader in this association.
  • There is a general consensus that severely stenotic aortic valve should be replaced during bypass surgery for severe coronary artery disease.
  • For moderate degree aortic stenosis, aortic valve replacement is usually performed during coronary bypass surgery.
  • Ischemic mitral regurgitation has recently received great attention from both diagnostic and therapeutic points of view.
  • Ischemic mitral regurgitation significantly alters the prognosis of the patient with coronary artery disease.
  • Severe ischemic mitral regurgitation should be corrected during coronary bypass surgery and mitral valve repair should be preferred to valve replacement.
  • For moderate degree ischemic mitral regurgitation, many authors prefer valve surgery with coronary bypass surgery.
  • In this review, the main characteristics of patients with coronary artery disease accompanying valvular heart disease and the therapeutic options based on individual valve pathology are discussed.
  • [MeSH-major] Coronary Artery Disease / complications. Heart Valve Diseases / complications. Mitral Valve Insufficiency / complications

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  • (PMID = 19581151.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 48
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15. |||....... 33%  Iung B, Vahanian A: Epidemiology of valvular heart disease in the adult. Nat Rev Cardiol; 2011 Mar;8(3):162-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidemiology of valvular heart disease in the adult.
  • Valvular heart disease remains common in industrialized countries, because the decrease in prevalence of rheumatic heart diseases has been accompanied by an increase in that of degenerative valve diseases.
  • Aortic stenosis and mitral regurgitation are the two most common types of valvular disease in Europe.
  • The prevalence of valvular disease increases sharply with age, owing to the predominance of degenerative etiologies.
  • The burden of heart valve disease in the elderly has an important impact on patient management, given the high frequency of comorbidity and the increased risk associated with intervention in this age group.
  • Endocarditis is an important etiology of valvular disease and is most commonly caused by Staphylococci.
  • Rheumatic heart disease remains prevalent in developing countries.
  • [MeSH-major] Aortic Valve / ultrasonography. Heart Valve Diseases / ultrasonography. Mitral Valve / ultrasonography
  • [MeSH-minor] Adult. Age Factors. Aortic Valve Stenosis / epidemiology. Aortic Valve Stenosis / pathology. Aortic Valve Stenosis / ultrasonography. Disease Progression. France / epidemiology. Humans. Mitral Valve Insufficiency / epidemiology. Mitral Valve Insufficiency / pathology. Mitral Valve Insufficiency / ultrasonography. Natriuretic Peptide, Brain / blood. World Health

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  • (PMID = 21263455.001).
  • [ISSN] 1759-5010
  • [Journal-full-title] Nature reviews. Cardiology
  • [ISO-abbreviation] Nat Rev Cardiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 114471-18-0 / Natriuretic Peptide, Brain
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16. |||....... 33%  Vahanian A, Iung B, Himbert D, Nataf P: Changing demographics of valvular heart disease and impact on surgical and transcatheter valve therapies. Int J Cardiovasc Imaging; 2011 Dec;27(8):1115-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Changing demographics of valvular heart disease and impact on surgical and transcatheter valve therapies.
  • Valvular heart disease remains frequent in industrialised countries since the decrease in frequency of rheumatic heart diseases has been accompanied by an increase in degenerative valve diseases.
  • The prevalence of valvular disease increases sharply with age, as a consequence of the predominance of degenerative valvular diseases.
  • Aortic stenosis and mitral regurgitation are the two most frequent diseases among patients referred because of valvular disease in Europe.
  • The burden of heart valve disease in the elderly has an important impact on patient management, given the frequency of comorbidity and the increase in the risk of interventions.
  • The changes in demographics explain why new procedures, such as transcatheter aortic valve implantation and percutaneous mitral valve repair, are potentially attractive in patients with high risk or even contraindications for surgery.
  • [MeSH-major] Aortic Valve Stenosis / epidemiology. Aortic Valve Stenosis / therapy. Cardiac Catheterization. Heart Valve Prosthesis Implantation / methods. Mitral Valve Insufficiency / epidemiology. Mitral Valve Insufficiency / therapy

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  • (PMID = 21347599.001).
  • [ISSN] 1875-8312
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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17. |||....... 33%  Bungard TJ, Sonnenberg B: Valvular heart disease: a primer for the clinical pharmacist. Pharmacotherapy; 2011 Jan;31(1):76-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Valvular heart disease: a primer for the clinical pharmacist.
  • Valvular heart disease is a commonly encountered clinical condition that is not taught in most undergraduate and graduate pharmacy programs, leaving the practicing pharmacist without basic knowledge to expand on and subsequently apply to direct patient care.
  • Unlike other areas of cardiology in which thousands of patients are recruited in many well-designed randomized clinical trials, data assessing treatments for valvular heart disease are limited and often consist of retrospective case series or observations.
  • Our goal is to provide a basic overview of chronic valvular heart disease, with emphasis on describing the common conditions requiring surgery and the available options, as well as common pharmacologic therapies used in this patient population.
  • Anomalies in valves can be broadly classified as stenosis and regurgitation.
  • Understanding the hemodynamic consequences of aortic stenosis, aortic regurgitation, mitral stenosis, and mitral regurgitation is imperative to effectively counsel patients surrounding disease progression and self-monitoring, use of vasodilators, and prophylaxis for endocarditis and rheumatic fever.
  • [MeSH-minor] Anticoagulants / therapeutic use. Aortic Valve Stenosis. Female. Heart Valve Prosthesis. Humans. Male. Mitral Valve Insufficiency. Mitral Valve Stenosis. Pharmacists. Time Factors

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  • (PMID = 21182361.001).
  • [ISSN] 1875-9114
  • [Journal-full-title] Pharmacotherapy
  • [ISO-abbreviation] Pharmacotherapy
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticoagulants
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18. |||....... 32%  Hwang HY, Kim KH, Ahn H: Attitude after a mild aortic valve lesion during rheumatic mitral valve surgery. J Thorac Cardiovasc Surg; 2014 May;147(5):1540-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Attitude after a mild aortic valve lesion during rheumatic mitral valve surgery.
  • OBJECTIVE: We evaluated whether rheumatic aortic valve disease of mild degree should be treated in patients undergoing mitral valve surgery.
  • METHODS: From 1992 to 2010, 197 patients (aged 52 [19-82] years, male:female = 60:137) who had rheumatic mitral valve disease and mild aortic valve disease were enrolled.
  • The aortic valve was untreated in 114 patients (no treatment group), repaired in 40 patients (aortic valvuloplasty group), and replaced in 43 patients (aortic valve replacement group).
  • In the no treatment group, progression-free survival in significant aortic valve disease at 5, 10, and 15 years was 98.7%, 91.3%, and 81.1%, respectively.
  • This was not superior in the aortic valvuloplasty group (85.9%, 77.6%, and 69.8%, respectively) than in the no treatment group.
  • Freedom from aortic valve disease was lower in patients with aortic stenosis than in those with aortic regurgitation in univariate and multivariable analyses (P < .001).
  • Reoperation was performed in 19 patients, including 2 aortic valve reoperations.
  • Aortic valve-related event-free survival was similar among the 3 groups.
  • CONCLUSIONS: Mild aortic valve disease in patients undergoing rheumatic mitral valve surgery could be left untreated, because preventive aortic valve operation does not result in better clinical and echocardiographic outcomes.
  • [MeSH-major] Aortic Valve / surgery. Aortic Valve Insufficiency / surgery. Aortic Valve Stenosis / surgery. Heart Valve Prosthesis Implantation. Mitral Valve / surgery. Rheumatic Heart Disease / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease Progression. Disease-Free Survival. Female. Hospital Mortality. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Patient Selection. Postoperative Complications / mortality. Postoperative Complications / surgery. Proportional Hazards Models. Reoperation. Retrospective Studies. Risk Assessment. Risk Factors. Severity of Illness Index. Time Factors. Treatment Outcome. Young Adult

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  • [Copyright] Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
  • (PMID = 23886033.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Observational Study
  • [Publication-country] United States
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19. |||....... 30%  Sakamoto Y, Hashimoto K: [Mitral valve surgery after aortic valve replacement]. Kyobu Geka; 2013 Jul;66(8 Suppl):644-8
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  • [Title] [Mitral valve surgery after aortic valve replacement].
  • The causes of mitral valve operation for patients who underwent aortic valve replacements (AVR)are rheumatic heart diseases, nonrheumatic insufficiency, infective endocarditis, prosthetic valve dysfunction and so on.
  • No specific recommendation for surgical strategy of mitral valve surgery for those patients has been described and surgical strategy should be selected to each patient.
  • The patients with rheumatic heart disease had higher risk for reoperation as compared with those with nonrheumatic heart disease and majority of patients with AVR who need reoperation because of mitral valve diseases had history of open or closed mitral commissurotomy.
  • Therefore, mitral valve repair should be limited to lesions in which excellent durability of the repair can be expected to prevent re-operation.
  • [MeSH-major] Aortic Valve / surgery. Mitral Valve / surgery
  • [MeSH-minor] Humans. Mitral Valve Insufficiency / surgery. Mitral Valve Stenosis / surgery. Reoperation

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  • (PMID = 23917178.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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20. |||....... 29%  Bakir I, Onan B, Onan IS, Gul M, Uslu N: Is rheumatic mitral valve repair still a feasible alternative?: indications, technique, and results. Tex Heart Inst J; 2013;40(2):163-9
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  • [Title] Is rheumatic mitral valve repair still a feasible alternative?: indications, technique, and results.
  • Rheumatic heart disease is still a major cause of mitral valve dysfunction in developing countries.
  • We present our early results of rheumatic mitral valve repair.
  • From August 2009 through July 2011, 60 patients (24 male and 36 female) with rheumatic disease underwent mitral repair.
  • Repair procedures included chordal and papillary muscle splitting, secondary chordal division, mitral ring annuloplasty (n=58), commissurotomy (n=36), chordal replacement (n=9), posterior leaflet extension (n=4), annular decalcification (n=2), and quadrangular resection (n=2).
  • Secondary procedures included tricuspid ring annuloplasty, left atrial ablation, obliteration of left atrial appendage, aortic valve replacement, and left atrial reduction.
  • Follow-up echocardiography revealed trivial or no mitral regurgitation (MR) in 35.5% and mild (1+) MR in 49.1% of patients.
  • The mean gradient over the mitral valve decreased significantly from 11 ± 5.9 mmHg to 3.5 ± 1.8 mmHg (P=0.001).
  • Because current techniques of mitral repair can effectively correct valve dysfunction in most patients with rheumatic disease, the number of repair procedures should be increased in developing countries to prevent complications of mechanical valve placement.
  • [MeSH-major] Cardiac Surgical Procedures. Mitral Valve / surgery. Mitral Valve Insufficiency / surgery. Mitral Valve Stenosis / surgery. Rheumatic Heart Disease / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Feasibility Studies. Female. Heart Valve Prosthesis Implantation. Humans. Male. Middle Aged. Mitral Valve Annuloplasty. Patient Selection. Recovery of Function. Retrospective Studies. Risk Assessment. Risk Factors. Texas. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 23678214.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3649788
  • [Keywords] NOTNLM ; Chordae tendineae/surgery / follow-up studies / mitral valve insufficiency/surgery / mitral valve prolapse/surgery / mitral valve stenosis/surgery / retrospective studies / rheumatic heart disease/surgery / treatment outcome
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21. |||....... 29%  Foramiti S, Biondini E, Bigolin T, Pasca S, Rossi P: Vanishing bile duct syndrome in non-Hodgkin lymphoma: a case report. Minerva Med; 2011 Aug;102(4):345-9
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  • A 64-year-old man with history of rheumatic heart disease complicated by steno-aortic insufficiency, mild mitral stenosis, atrial fibrillation, left kidney damage, bilateral glaucoma, left internal jugular vein thrombosis, bronchopneumonia, NHL type B (stage IV) treated with chemo and radiotherapy was admitted to our department for jaundice with predominantly cholestatic component.
  • A special attention to abnormal liver function is necessary to diagnose this syndrome, because often the tests are interpreted as disseminated (stage IV) disease and not as a possible expression of VBDS which could, in some cases, be attenuated by UDCA and by steroids therapy.


22. |||....... 29%  Mihos CG, Santana O, Lamelas J: Intermediate results of transaortic edge-to-edge repair of the mitral valve in patients undergoing aortic valve replacement. J Heart Valve Dis; 2014 Jan;23(1):91-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intermediate results of transaortic edge-to-edge repair of the mitral valve in patients undergoing aortic valve replacement.
  • BACKGROUND AND AIM OF THE STUDY: The study aim was to evaluate the safety and efficacy of a transaortic edge-to-edge mitral valve repair in patients undergoing aortic valve replacement (AVR) who were considered to be at high risk for double-valve surgery.
  • METHODS: All patients deemed to be at high surgical risk for standard double-valve surgery, and who instead underwent AVR with transaortic edge-to-edge mitral valve repair between September 2008 and October 2012 at the authors' institution, were analyzed retrospectively.
  • Intraoperative transesophageal and follow-up transthoracic echocardiography were performed to evaluate adequacy of the repair and to assess for any recurrence of mitral regurgitation (MR).
  • The aortic valve lesion was classified as stenosis (n = 45), insufficiency (n = 6), or prosthetic valve insufficiency (n = 4), and the mitral valve lesion as functional (n = 16), degenerative calcification (n = 27), or rheumatic (n = 12).
  • CONCLUSION: In high-risk patients undergoing AVR with grade 3-4+ MR, a transaortic edge-to-edge mitral valve repair may be a safe and effective alternative to conventional double-valve surgery.
  • [MeSH-major] Aortic Valve / surgery. Cardiac Surgical Procedures / methods. Heart Valve Prosthesis Implantation / methods. Mitral Valve / surgery
  • [MeSH-minor] Aged. Aortic Valve Insufficiency / complications. Aortic Valve Insufficiency / surgery. Aortic Valve Stenosis / complications. Aortic Valve Stenosis / surgery. Female. Humans. Male. Mitral Valve Insufficiency / classification. Mitral Valve Insufficiency / complications. Mitral Valve Insufficiency / surgery. Retrospective Studies. Severity of Illness Index. Stroke Volume. Surgical Procedures, Minimally Invasive

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  • (PMID = 24779334.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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23. |||....... 27%  Shetty RK, Vivek G, Naha K, Rau NR, Nayak K: Quadrivalvular heart disease of mixed congenital and rheumatic aetiology with concomitant ostium secundum atrial septal defect and Ebstein's anomaly of the tricuspid valve. BMJ Case Rep; 2013;2013
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quadrivalvular heart disease of mixed congenital and rheumatic aetiology with concomitant ostium secundum atrial septal defect and Ebstein's anomaly of the tricuspid valve.
  • We describe a 34-year-old man with an ostium secundum atrial septal defect, Ebstein's anomaly of the tricuspid valve with severe tricuspid regurgitation, congenital valvular pulmonary stenosis, rheumatic mitral stenosis and regurgitation with aortic regurgitation, who presented with decompensated heart failure after developing atrial fibrillation.
  • [MeSH-major] Ebstein Anomaly / complications. Heart Defects, Congenital / complications. Heart Failure / etiology. Heart Septal Defects, Atrial / complications. Heart Valve Diseases / complications. Heart Valves / pathology. Rheumatic Diseases / complications
  • [MeSH-minor] Adult. Aorta / pathology. Aortic Valve Insufficiency / complications. Atrial Fibrillation / etiology. Atrial Septum / pathology. Humans. Male. Mitral Valve Stenosis / complications. Mitral Valve Stenosis / pathology. Pulmonary Valve Stenosis / complications. Pulmonary Valve Stenosis / pathology. Tricuspid Valve Insufficiency / complications


24. |||....... 25%  Colquhoun SM, Carapetis JR, Kado JH, Reeves BM, Remenyi B, May W, Wilson NJ, Steer AC: Pilot study of nurse-led rheumatic heart disease echocardiography screening in Fiji--a novel approach in a resource-poor setting. Cardiol Young; 2013 Aug;23(4):546-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pilot study of nurse-led rheumatic heart disease echocardiography screening in Fiji--a novel approach in a resource-poor setting.
  • We designed a pilot study of a training module for nurses to perform rheumatic heart disease echocardiography screening in a resource-poor setting.
  • The aim was to determine whether nurses given brief, focused, basic training in echocardiography could follow an algorithm to potentially identify cases of rheumatic heart disease requiring clinical referral, by undertaking basic two-dimensional and colour Doppler scans.
  • The nurses' skills were tested on a blinded cohort of 50 children, and the results were compared for sensitivity and specificity against echocardiography undertaken by an expert, using standardised echocardiography definitions for definite and probable rheumatic heart disease.
  • Analysis of the two nurses' results revealed that when a mitral regurgitant jet length of 1.5 cm was used as the trigger for rheumatic heart disease identification, they had a sensitivity of 100% and 83%, respectively, and a specificity of 67.4% and 79%, respectively.
  • This pilot supports the principle that nurses, given brief focused training and supervised field experience, can follow an algorithm to undertake rheumatic heart disease echocardiography in a developing country setting to facilitate clinical referral with reasonable accuracy.
  • These results warrant further research, with a view to developing a module to guide rheumatic heart disease echocardiographic screening by nurses within the existing public health infrastructure in high-prevalence, resource-poor regions.
  • [MeSH-major] Aortic Valve Insufficiency / ultrasonography. Echocardiography, Doppler, Color / nursing. Education, Nursing / methods. Mitral Valve Insufficiency / ultrasonography. Mitral Valve Stenosis / ultrasonography. Rheumatic Heart Disease / ultrasonography

  • Genetic Alliance. consumer health - Heart Disease.
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  • (PMID = 23040535.001).
  • [ISSN] 1467-1107
  • [Journal-full-title] Cardiology in the young
  • [ISO-abbreviation] Cardiol Young
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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25. ||........ 24%  Ozdemir AC, Emrecan B, Baltalarli A: Bileaflet versus posterior-leaflet-only preservation in mitral valve replacement. Tex Heart Inst J; 2014 Apr;41(2):165-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bileaflet versus posterior-leaflet-only preservation in mitral valve replacement.
  • In the present study of mitral valve replacement, we investigated whether complete preservation of both leaflets (that is, the subvalvular apparatus) is superior to preservation of the posterior leaflet alone.
  • Seventy patients who underwent mitral valve replacement in our clinic were divided into 2 groups: MVR-B (n=16), in whom both leaflets were preserved, and MVR-P (n=54), in whom only the posterior leaflet was preserved.
  • No differences were found between the 2 groups in their need for inotropic agents or intra-aortic balloon pump support, or in cross-clamp time, duration of intensive care unit or hospital stays, postoperative development of new atrial fibrillation, or mortality rates.

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  • [Cites] Ann Thorac Surg. 1988 Jan;45(1):28-34 [3337572.001]
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  • (PMID = 24808776.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4004467
  • [Keywords] NOTNLM ; Chordae tendineae/surgery / heart valve prosthesis implantation / mitral valve insufficiency / mitral valve stenosis / mitral valve/surgery / papillary muscles/surgery / postoperative complications/prevention & control / retrospective studies / rheumatic heart disease / treatment outcome / ventricular function, left
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26. ||........ 24%  Pollari F, Santarpino G, Pfeiffer S, Fischlein T: [Double mitro-aortic valve replacement in a high-risk patient: the sutureless way]. G Ital Cardiol (Rome); 2014 Feb;15(2):128-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Double mitro-aortic valve replacement in a high-risk patient: the sutureless way].
  • The mitro-aortic disease in high-risk patients is a challenge for the cardiac surgeon because minimally invasive techniques are difficult to apply.
  • We report the first case in the literature of a 78-year-old woman affected by severe rheumatic steno-insufficiency of aortic and mitral valves at high surgical risk.
  • The patient was successfully treated by mitral valve replacement with a biological prosthesis and concomitant aortic valve replacement with a sutureless prosthesis.
  • [MeSH-major] Aortic Valve Stenosis / surgery. Heart Valve Prosthesis Implantation / methods. Mitral Valve Insufficiency / surgery

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  • (PMID = 24625854.001).
  • [ISSN] 1827-6806
  • [Journal-full-title] Giornale italiano di cardiologia (2006)
  • [ISO-abbreviation] G Ital Cardiol (Rome)
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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27. ||........ 21%  Boudoulas KD, Ravi Y, Garcia D, Saini U, Sofowora GG, Gumina RJ, Sai-Sudhakar CB: Type of Valvular Heart Disease Requiring Surgery in the 21st Century: Mortality and Length-of-Stay Related to Surgery. Open Cardiovasc Med J; 2013;7:104-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Type of Valvular Heart Disease Requiring Surgery in the 21st Century: Mortality and Length-of-Stay Related to Surgery.
  • AIM: While the incidence of rheumatic heart disease has declined dramatically over the last half-century, the number of valve surgeries has not changed.
  • This study was undertaken to define the most common type of valvular heart disease requiring surgery today, and determine in-hospital surgical mortality and length-of-stay (LOS) for isolated aortic or mitral valve surgery in a United States tertiary-care hospital.
  • Patients only with isolated aortic or mitral valve surgery were analyzed.
  • RESULTS: From 915 patients undergoing at least aortic or mitral valve surgery, the majority had concomitant cardiac proce-dures mostly coronary artery bypass grafting (CABG); only 340 patients had isolated aortic (n=204) or mitral (n=136) valve surgery.
  • In-hospital surgical mortality for mitral regurgitation (n=119), aortic stenosis (n=151), aortic insufficiency (n=53) and mitral stenosis (n=17) was 2.5% (replacement 3.4%; repair 1.6%), 3.9%, 5.6% and 5.8%, respectively (p=NS).
  • Median LOS for aortic insufficiency, aortic stenosis, mitral regurgitation, and mitral stenosis was 7, 8, 9 (replacement 11.5; repair 7) and 11 days, respectively (p<0.05 for group).
  • CONCLUSIONS: Aortic stenosis and mitral regurgitation are the most common valvular lesions requiring surgery today.
  • Surgery for isolated aortic or mitral valve disease has low in-hospital mortality with modest LOS.

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  • (PMID = 24339838.001).
  • [ISSN] 1874-1924
  • [Journal-full-title] The open cardiovascular medicine journal
  • [ISO-abbreviation] Open Cardiovasc Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC3856389
  • [Keywords] NOTNLM ; Heart valve / aortic valve / mitral valve / outcomes. / surgery
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28. ||........ 21%  Cavalca V, Tremoli E, Porro B, Veglia F, Myasoedova V, Squellerio I, Manzone D, Zanobini M, Trezzi M, Di Minno MN, Werba JP, Tedesco C, Alamanni F, Parolari A: Oxidative stress and nitric oxide pathway in adult patients who are candidates for cardiac surgery: patterns and differences. Interact Cardiovasc Thorac Surg; 2013 Dec;17(6):923-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: We investigated whether oxidative stress and the arginine/nitric oxide pathway differ in control subjects and in adult patients who are candidates for the three most common cardiac surgical operations: coronary bypass surgery, aortic valve replacement for calcific non-rheumatic aortic stenosis or mitral valve repair for degenerative mitral insufficiency.
  • METHODS: In this prospective observational study, we studied 165 consecutive patients undergoing surgery from January to June 2011 (coronary bypass surgery, n = 63; aortic valve replacement for calcific non-rheumatic aortic stenosis, n = 51; mitral valve repair for degenerative mitral insufficiency, n = 51).
  • Concerning the differences among surgical procedures, higher oxidative stress and a major imbalance of the ratio between substrate and inhibitors of nitric oxide synthesis were evidenced in patients who were candidates for mitral valve repair with respect to coronary bypass surgery patients and patients with calcific non-rheumatic aortic stenosis.
  • Patients affected by mitral valve regurgitation show more pronounced perturbations in these pathways.
  • [MeSH-major] Aortic Valve / pathology. Aortic Valve Stenosis / surgery. Calcinosis / surgery. Coronary Artery Bypass. Coronary Artery Disease / surgery. Heart Valve Prosthesis Implantation. Mitral Valve Insufficiency / surgery. Nitric Oxide / metabolism. Oxidative Stress

  • MedlinePlus Health Information. consumer health - Coronary Artery Bypass Surgery.
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  • HSDB. structure - NITRIC OXIDE.
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  • (PMID = 24014619.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Observational Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biological Markers; 31C4KY9ESH / Nitric Oxide; Aortic Valve, Calcification of
  • [Other-IDs] NLM/ PMC3829501 [Available on 12/01/14]
  • [Keywords] NOTNLM ; Aortic valve stenosis / Coronary artery disease / Mitral valve regurgitation / Nitric oxide / Oxidative stress
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29. ||........ 18%  Stajić Z, Mijailović Z, Bogavac M, Lazović B, Stojanović M: [Cardiovascular diseases during pregnancy and delivery]. Med Pregl; 2013 Nov-Dec;66(11-12):507-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PHYSIOLOGICALLY ADAPTED MECHANISMS OF THE CARDIOVASCULAR SYSTEM IN PREGNANCY: It is normal that during pregnancy some physiological adaptive changes of the cardiovascular system occur and they may contribute to the deterioration of the clinical cardiac status of a patient with preexisting or acquired cardiovascular disease.
  • The most frequent acquired cardiovascular diseases during pregnancy include arrhythmias, ischemic heart disease, rheumatic mitral stenosis and insufficiency, arterial hypertension and aortic dissection.
  • CONCLUSION: In all cases of pregnancy associated with cardiovascular diseases, early recognition of cardiovascular disease is crucial, as well as correct diagnosis and referral to a tertiary centre equipped for a multidisciplinary approach of specialists experienced in high-risk pregnancies and deliveries in order to prevent maternal mortality.

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  • (PMID = 24575641.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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30. |......... 11%  Cooper IF, Siadaty MS: 'Hormones' associated with 'Heart Replacement': Top Publications. BioMedLib Review; Hormone;HeartReplacement:705906167. ISSN: 2331-5717. 2014/5/3
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  • Chen QQ et al: [Relationship between early spontaneous cardioversion of atrial fibrillation and thyroid hormone metabolism after mitral replacement in patients with rheumatic heart disease].
  • Bao SS et al: Repairing a "broken heart" with hormone replacement therapy: case report of cardiogenic shock due to undiagnosed pituitary insufficiency.
  • Biederman RW et al: LV reverse remodeling imparted by aortic valve replacement for severe aortic stenosis; is it durable? A cardiovascular MRI study sponsored by the American Heart Association.
  • Hodis HN et al: The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 2: comparative risks.
  • Hodis HN et al: The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 1: comparison of therapeutic efficacy.
  • Fait T et al: Coronary heart disease and hormone replacement therapy - from primary and secondary prevention to the window of opportunity.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705906167.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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2. Definitions


3. Related RMF webpages
1. insufficiency aortic rheumatic stenosis with mitral disease
2. insufficiency aortic rheumatic stenosis with mitral disease with tricuspid disease
3. insufficiency aortic rheumatic disease mitral
4. insufficiency mitral rheumatic with aortic valve disease
5. stenosis aortic valve rheumatic with mitral disease
6. stenosis aortic valve rheumatic with insufficiency or regurgitation with mitral valve
7. insufficiency mitral rheumatic with aortic valve disease with tricuspid disease
8. stenosis aortic valve rheumatic tricuspid disease with mitral disease
9. insufficiency mitral rheumatic tricuspid disease with aortic disease
10. insufficiency aortic rheumatic disease mitral with tricuspid disease
11. stenosis tricuspid with insufficiency or regurgitation with aortic disease with mitral disease
12. stenosis aortic valve rheumatic with insufficiency or regurgitation
13. insufficiency mitral rheumatic tricuspid disease
14. endocarditis aortic valve rheumatic with mitral disease
15. stenosis aortic valve rheumatic with insufficiency or regurgitation with tricuspid valve
16. stenosis aortic valve rheumatic tricuspid disease
17. insufficiency aortic with mitral disease
18. insufficiency mitral with aortic valve disease
19. stenosis mitral with aortic valve disease
20. insufficiency mitral with aortic valve disease with tricuspid disease
21. insufficiency tricuspid with aortic disease with mitral disease
22. insufficiency mitral tricuspid disease with aortic disease
23. insufficiency aortic tricuspid disease with mitral disease
24. stenosis tricuspid with mitral disease with aortic disease
25. stenosis tricuspid with insufficiency or regurgitation with aortic disease
26. non rheumatic mitral valve stenosis
27. mitral aortic stenosis
28. stenosis mitral with insufficiency or regurgitation
29. insufficiency mitral with obstruction or stenosis
30. aortic valve stenosis with insufficiency disorder
31. insufficiency mitral tricuspid disease
32. stenosis tricuspid with mitral disease
33. stenosis mitral with tricuspid valve disease
34. mitral valve stenosis disease finding
35. endocarditis aortic valve with mitral disease
36. insufficiency aortic tricuspid disease
37. insufficiency tricuspid with aortic disease
38. mitral and aortic valve disease nos disorder
39. stenosis tricuspid with aortic disease
40. aortic valve stenosis disease finding
41. mitral incompetence rheumatic
42. mitral obstruction rheumatic
43. endocarditis mitral valve rheumatic
44. chronic rheumatic mitral valve disorder
45. insufficiency myocardial rheumatic
46. aortic incompetence rheumatic
47. failure aortic rheumatic
48. endocarditis aortic valve rheumatic
49. mitral valve insufficiency
50. insufficiency mitral valve

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