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1. Biomedical articles (top 50; 2009 to 2014)
1. |||||..... 50%  Kim CW, Kim MJ, Park SB, Han SH: A case of rheumatoid arthritis with unilateral knee synovial hypertrophy in hemiplegia. Ann Rehabil Med; 2012 Feb;36(1):144-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of rheumatoid arthritis with unilateral knee synovial hypertrophy in hemiplegia.
  • From the results of the magnetic resonance imaging (MRI), synovial proliferative disease, infectious arthritis, or gouty arthritis was suspected.
  • We performed a blood laboratory test to detect rheumatologic diseases, knee joint aspiration, and bone scan for differential diagnosis, and were able to diagnose rheumatoid arthritis (RA) from the results of blood laboratory, physical examination, and bone scan.
  • Herein, we report a case of rheumatoid arthritis with unilateral knee synovial hypertrophy in hemiplegia.
  • If a right hemiplegic patient has recurrent pain on the left knee and synovial hypertrophy, and fails to respond to treatment for osteoarthritis, early detection by evaluation for rheumatic disease is crucial to prevent severe sequelae influencing rehabilitation of hemiplegia.

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  • (PMID = 22506248.001).
  • [ISSN] 2234-0653
  • [Journal-full-title] Annals of rehabilitation medicine
  • [ISO-abbreviation] Ann Rehabil Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3309335
  • [Keywords] NOTNLM ; Hemiplegia / Rheumatoid arthritis / Synovial hypertrophy
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2. |||....... 31%  Atalar AC, Sungur M, Demirhan M, Ozger H: Neuropathic arthropathy of the shoulder associated with syringomyelia: a report of six cases. Acta Orthop Traumatol Turc; 2010;44(4):328-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Initial diagnosis, previous treatment, and radiological and clinical follow-up findings were reviewed.
  • The mean age at diagnosis was 44.2 years.
  • Biopsy was performed in 4 patients before definitive diagnosis, and synovial hypertrophy and necrotic bone was found.
  • As a conclusion, neuropathic arthropathy of the shoulder is rare, and correct diagnosis is possible by careful physical and neurological examination and pathologic evaluation when needed.

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  • (PMID = 21252611.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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3. |||....... 27%  Tezcan ME, Ekinci O, Uçar M, Göker B: Sterile osteitis and suppurative arthritis associated with pannus responding to colchicine. Case Rep Rheumatol; 2013;2013:249471
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, he had clinical response to colchicine and the synovial hypertrophy and the pannus in the MRI of his left shoulder resolved.

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  • (PMID = 23984159.001).
  • [ISSN] 2090-6889
  • [Journal-full-title] Case reports in rheumatology
  • [ISO-abbreviation] Case Rep Rheumatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3741952
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4. |......... 12%  Cooper IF, Siadaty MS: 'Qualitative Concepts' associated with 'Cartilage Hypertrophy': Top Publications. BioMedLib Review; QualitativeConcept;CartilageHypertrophy:706365854. ISSN: 2331-5717. 2014/7/26
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  • [Title] 'Qualitative Concepts' associated with 'Cartilage Hypertrophy': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Qualitative Concept' for 'cartilage hypertrophy'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Qualitative Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 19 publications, and group two 1497 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Cells' associated with 'Cartilage Hypertrophy': Top Publications.
  • Cameron TL et al: Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy.
  • Bian L et al: Coculture of human mesenchymal stem cells and articular chondrocytes reduces hypertrophy and enhances functional properties of engineered cartilage.
  • Tchetina EV et al: Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production.
  • Vital EM et al: Premature osteoarthritis of the knee associated with cartilage hypertrophy and phalangeal dysgenesis.
  • Chen-An P et al: Investigation of chondrocyte hypertrophy and cartilage calcification in a full-depth articular cartilage explants model.
  • Adams ME: Cartilage hypertrophy following canine anterior cruciate ligament transection differs among different areas of the joint.
  • HUBLE J: Effects of desoxycorticosterone acetate on chondrogenesis and cartilage hypertrophy in the young chick.
  • Stott NS et al: Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type X collagen.
  • Bobacz K et al: Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706365854.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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5. |||....... 27%  Micu MC, Bogdan GD, Fodor D: Steroid injection for hip osteoarthritis: efficacy under ultrasound guidance. Rheumatology (Oxford); 2010 Aug;49(8):1490-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Synovial hypertrophy was reduced in 75% of the hips after 1 and 3 months vs baseline (P < 0.001).
  • In the group of controls, hip walking pain VAS, Lequesne index and synovial hypertrophy were not changed at 3 months vs baseline (P > 0.05).
  • CONCLUSION: US-guided steroid injections in hip OA is an efficacious and safe therapeutic approach to achieve pain control and reduction of synovial hypertrophy avoiding the use of X-ray-guided procedure.

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  • [CommentIn] Rheumatology (Oxford). 2011 Apr;50(4):812-3; author reply 813 [21292739.001]
  • [CommentIn] Rheumatology (Oxford). 2010 Aug;49(8):1427-8 [20360036.001]
  • (PMID = 20338889.001).
  • [ISSN] 1462-0332
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Steroids
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6. |......... 12%  Cooper IF, Siadaty MS: 'Spatial Concepts' associated with 'Unilateral Hypertrophy': Top Publications. BioMedLib Review; SpatialConcept;UnilateralHypertrophy:706247748. ISSN: 2331-5717. 2014/9/24
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  • [Title] 'Spatial Concepts' associated with 'Unilateral Hypertrophy': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Spatial Concept' for 'unilateral hypertrophy'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Spatial Concept'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 27 publications, and group two 310 publications.
  • Here are the top 10.
  • Cooper IF et al: 'Hormones' associated with 'Unilateral Hypertrophy': Top Publications.
  • Onishi E et al: Unilateral atlantal lateral mass hypertrophy associated with atlanto-occipital fusion.
  • Netto AB et al: An unusual case of unilateral limb hypertrophy: Lipoma of sacral roots.
  • Atalay B et al: Unilateral axis facet hypertrophy--a rare case of irreducible rotatory atlantoaxial dislocation and a review of the literature.
  • Goel A et al: Unilateral atlantal facetal hypertrophy.
  • Wang BH et al: Isolated unilateral temporalis muscle hypertrophy.
  • Katsetos CD et al: Painful unilateral temporalis muscle enlargement: reactive masticatory muscle hypertrophy.
  • Rasić D et al: A case of an unilateral tonsillar hypertrophy caused by actinomycosis.
  • Kim CW et al: A case of rheumatoid arthritis with unilateral knee synovial hypertrophy in hemiplegia.
  • Das KK et al: Unilateral lateral mass hypertrophy: An extremely rare congenital anomaly of atlas.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 706247748.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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7. |||....... 27%  Laurell L, Court-Payen M, Nielsen S, Zak M, Boesen M, Fasth A: Ultrasonography and color Doppler in juvenile idiopathic arthritis: diagnosis and follow-up of ultrasound-guided steroid injection in the ankle region. A descriptive interventional study. Pediatr Rheumatol Online J; 2011;9(1):4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasonography and color Doppler in juvenile idiopathic arthritis: diagnosis and follow-up of ultrasound-guided steroid injection in the ankle region. A descriptive interventional study.
  • Doppler-US detected synovial hypertrophy, effusion and hyperemia and US was used for guidance of steroid injection and to assess treatment efficacy.
  • All patients were assessed clinically, by US (synovial hypertrophy, effusion) and by color Doppler (synovial hyperemia) before and 4 weeks after US-guided steroid injection.
  • Normalization or regression of synovial hypertrophy was obtained in 89%, and normalization of synovial hyperemia in 89%.
  • CONCLUSIONS: US enabled exact anatomical location of synovial inflammation in the ankle region of JIA patients.
  • Normalization or regression of synovial hypertrophy and hyperemia was achieved in most cases, which supports the notion that US is an important tool in the management of ankle involvement in JIA.

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  • (PMID = 21276257.001).
  • [ISSN] 1546-0096
  • [Journal-full-title] Pediatric rheumatology online journal
  • [ISO-abbreviation] Pediatr Rheumatol Online J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3041992
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8. ||||||.... 56%  Gajjar SM, Platts A, Dowd G: Synovial hypertrophy causing recurrent hemarthrosis after total knee replacement. J Knee Surg; 2010 Mar;23(1):25-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synovial hypertrophy causing recurrent hemarthrosis after total knee replacement.
  • We report three patients with late-onset recurrent hemarthrosis following total knee replacement due to synovial hypertrophy and impingement, which were successfully treated by embolization.
  • [MeSH-major] Arthroplasty, Replacement, Knee / adverse effects. Hemarthrosis / etiology. Synovial Membrane / pathology
  • [MeSH-minor] Aged. Embolization, Therapeutic. Female. Humans. Hypertrophy / complications. Hypertrophy / etiology. Male. Middle Aged. Recurrence

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  • (PMID = 20812578.001).
  • [ISSN] 1538-8506
  • [Journal-full-title] The journal of knee surgery
  • [ISO-abbreviation] J Knee Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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9. ||||...... 36%  Miller E, Uleryk E, Doria AS: Evidence-based outcomes of studies addressing diagnostic accuracy of MRI of juvenile idiopathic arthritis. AJR Am J Roentgenol; 2009 May;192(5):1209-18
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Our objective was to semiquantitatively evaluate the diagnostic accuracy of MRI for evaluation of synovium and cartilage of peripheral joints in juvenile idiopathic arthritis (JIA) according to the levels of evidence and recommendations of the Canadian Task Force on Periodic Health Examination guidelines.
  • Two independent reviewers assessed whether the currently available MRI techniques are accurate for diagnosis of synovial hypertrophy and cartilage degeneration in children with JIA.
  • Overall, there is fair (grade B) strength of evidence that MRI is an accurate diagnostic method for evaluating synovium and cartilage and for assessing clinical responsiveness to treatment in peripheral joints in JIA.
  • [MeSH-major] Arthritis, Juvenile / diagnosis. Magnetic Resonance Imaging
  • [MeSH-minor] Child. Diagnosis, Differential. Evidence-Based Medicine. Humans. Outcome Assessment (Health Care). Sensitivity and Specificity


10. |||....... 28%  Chávez-López MA, Hernández-Díaz C, Moya C, Pineda C, Ventura-Ríos L, Möller I, Naredo E, Espinosa R, Peña A, Rosas-Cabral A, Filippucci E: Inter- and intra-observer agreement of high-resolution ultrasonography and power Doppler in assessment of joint inflammation and bone erosions in patients with rheumatoid arthritis. Rheumatol Int; 2013 Jan;33(1):173-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The OMERACT preliminary definitions of joint effusion, synovial hypertrophy, bone erosions and tenosynovitis were adopted.
  • Mean kappa value for joint effusion was good, 0.654 (85%); synovial hypertrophy, 0.550 (77.2%); power Doppler signal, 0.550 (82.5%); bone erosions, 0.549 (81%); and tenosynovitis, 0.500 (91.5%).
  • Mean and overall intra-observer agreement for semiquantitative score was good for joint effusion, 0.630 (77.2%) and bone erosions, 0.605 (56.25%); and moderate to synovial hypertrophy, 0.476 (65%) and power Doppler signal, 0.471 (80%).
  • Mean kappa value for joint effusion was 0.381 (95%), synovial hypertrophy, 0.447 (72%); power Doppler signal, 0.496 (81%); bone erosions, 0.294 (81%); and tenosynovitis, 0.030 (66%).
  • Mean and overall inter-observer agreement for semiquantitative score was poor for joint effusion, 0.325 (57%) and bone erosions, 0.360 (43%); and moderate to synovial hypertrophy, 0.431 (55%) and power Doppler signal, 0.496 (81%).


11. |||....... 28%  Gok M, Erdem H, Gogus F, Yilmaz S, Karadag O, Simsek I, Sagkan RI, Saglam M, Musabak U, Dinc A, Pay S: Relationship of ultrasonographic findings with synovial angiogenesis modulators in different forms of knee arthritides. Rheumatol Int; 2013 Apr;33(4):879-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relationship of ultrasonographic findings with synovial angiogenesis modulators in different forms of knee arthritides.
  • The increased power Doppler (PD) signals determined by ultrasonography is an indirect marker of synovial vascularity in arthritis.
  • We aimed to investigate relationship between ultrasonographic findings and synovial angiogenesis modulators.
  • Cumulative effusion, synovial hypertrophy, and PD signal scores were calculated in arthritic joints.
  • In synovial fluid samples, angiogenesis inhibitors (angiostatin, thrombospondin-1, and endostatin) and stimulators [bFGF (basic fibroblast growth factor), angiopoietin-1] were studied.
  • Synovial hypertrophy scores were higher in RA and spondylarthritis than in OA and BD.
  • Synovial angiostatin and bFGF levels were significantly higher in patients with inflammatory arthritis than in OA.
  • Synovial hypertrophy scores were positively correlated with angiostatin and bFGF levels and negatively correlated with thrombospondin-1.
  • [MeSH-major] Arthritis, Rheumatoid / ultrasonography. Behcet Syndrome / ultrasonography. Knee Joint / ultrasonography. Osteoarthritis, Knee / ultrasonography. Spondylarthropathies / ultrasonography. Synovial Fluid / drug effects

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  • (PMID = 22811011.001).
  • [ISSN] 1437-160X
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / Angiogenesis Inhibitors; 0 / Angiopoietin-1; 0 / Endostatins; 0 / Thrombospondin 1; 103107-01-3 / Fibroblast Growth Factor 2; 86090-08-6 / Angiostatins
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12. |||....... 27%  Laor T, Crawford AH: Idiopathic chondrolysis of the hip in children: early MRI findings. AJR Am J Roentgenol; 2009 Feb;192(2):526-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSION: A geometric region of abnormal signal intensity centered in the proximal femoral epiphysis, accompanied by ipsilateral ill-defined acetabular bone marrow edema, mild synovial hypertrophy, and minimal if any joint fluid, in a child with a painful stiff hip are early MRI findings characteristic of idiopathic chondrolysis.
  • [MeSH-major] Cartilage Diseases / diagnosis. Cartilage, Articular / pathology. Hip Joint / pathology. Magnetic Resonance Imaging / methods

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  • (PMID = 19155420.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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13. |||....... 27%  Macchioni P, Magnani M, Mulè R, Galletti S, Catanoso M, Pignotti E, Boiardi L, Meliconi R, Salvarani C: Ultrasonographic predictors for the development of joint damage in rheumatoid arthritis patients: a single joint prospective study. Clin Exp Rheumatol; 2013 Jan-Feb;31(1):8-17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Two hundred and forty MCP joints of 24 patients with RA were prospectively evaluated both clinically and by ultrasound (US) at time 0, at six months and 12 months, in order to collect the following variables: presence of synovial hypertrophy and power-Doppler (PD) vascularisation both graded on a semiquantitative (0-3) scale, and the number and dimension of bone erosions.
  • RESULTS: Fifteen out of seventeen (88%) of the new eroded joints on x-rays examination had persistent PD vascularity and 14/17 (82%) had persistent synovial thickening (p=0.001 and p=0.02, vs. non-eroded joints, respectively).
  • In multiple conditional logistic regression analysis, the most important factor associated with the development of radiological joint damage was the presence of a synovial PD score ≥2 on two or more US evaluations (OR 8.51 [95%CI 1.84-39.48] for Rx new erosions and OR 8.30 [95%CI 1.97-38.9] for increased S/vdH local joint score).
  • Both baseline synovial score ≥2 and presence of Rx erosions were also significantly associated with the development of radiological joint damage.
  • CONCLUSIONS: At the single joint level, the presence of US determined synovial thickness and PD signal at baseline and the persistent PD signal over time have relevant prognostic value for the development of articular damage in the same MCP joints of RA patients.


14. |||....... 27%  Kawashiri SY, Kawakami A: [Musculoskeletal ultrasonography in rheumatoid arthritis]. Clin Calcium; 2012 Feb;22(2):187-92
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  • Ultrasonography is able to accurately evaluate synovial lesion, and it detect bone lesion in the patients with rheumatoid arthritis (RA) in early stage.
  • Power Doppler signals with synovial hypertrophy mean disease activity of RA.
  • Therefore, ultrasonography is very useful in not only the early diagnosis but also the evaluation of disease activity as well as evaluation of treatment choice in the patients with RA.
  • [MeSH-minor] Early Diagnosis. Humans. Musculoskeletal System / ultrasonography. Patient Education as Topic


15. |||....... 27%  Riente L, Delle Sedie A, Sakellariou G, Filippucci E, Meenagh G, Iagnocco A, Cioffi E, Valesini G, Grassi W, Montecucco C, Bombardieri S: Ultrasound imaging for the rheumatologist XXXVIII. Sonographic assessment of the hip in psoriatic arthritis patients. Clin Exp Rheumatol; 2012 Mar-Apr;30(2):152-5
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  • Bilateral examination of the hip was performed to detect joint effusion, synovial hypertrophy, irregularity of femoral head and neck profile as seen in erosions and/or osteophytes.
  • Synovial hypertrophy was present in 12 out of 20 hips (60%) associated with effusion (9.3% of all hip joints) and only 1 of them showed PD signal.
  • Small effusion without synovial proliferation was imaged in 8 out of 20 hips (40%).
  • On the whole 14 out of 65 patients (21%) had joint effusion with or without synovial hypertrophy using US.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cell Proliferation. Female. Femur Head / ultrasonography. Femur Neck / ultrasonography. Humans. Hypertrophy. Italy. Male. Middle Aged. Northern Ireland. Predictive Value of Tests. Prognosis. Severity of Illness Index. Synovial Membrane / ultrasonography. Young Adult


16. |||....... 27%  Bevers K, Zweers MC, van den Ende CH, Martens HA, Mahler E, Bijlsma JW, Wakefield RJ, van den Hoogen FH, den Broeder AA: Ultrasonographic analysis in knee osteoarthritis: evaluation of inter-observer reliability. Clin Exp Rheumatol; 2012 Sep-Oct;30(5):673-8
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  • The acquisition protocol comprised medial meniscus protrusion, synovial hypertrophy, effusion, infrapatellar bursitis and cartilage thickness.
  • RESULTS: Inter-observer agreement (κ-value) was moderate for protrusion of the medial meniscus (0.54), good for infrapatellar bursitis (0.66) and effusion (0.74), excellent for Bakers' cyst (0.85) and poor for the detection of synovial hypertrophy (-0.08).

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  • (PMID = 22765952.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Italy
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17. |||....... 27%  Hemke R, van Rossum MA, van Veenendaal M, Terra MP, Deurloo EE, de Jonge MC, van den Berg JM, Dolman KM, Kuijpers TW, Maas M: Reliability and responsiveness of the Juvenile Arthritis MRI Scoring (JAMRIS) system for the knee. Eur Radiol; 2013 Apr;23(4):1075-83
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  • MRI features of synovial hypertrophy, bone marrow changes, cartilage lesions and bone erosions were independently scored by five readers using the JAMRIS system.
  • Concerning therapy response, the mean synovial hypertrophy scores decreased significantly (mean 1.1 point; P < 0.001, SRM = -0.65).


18. |||....... 27%  Hemke R, van Veenendaal M, Kuijpers TW, van Rossum MA, Maas M: Increasing feasibility and patient comfort of MRI in children with juvenile idiopathic arthritis. Pediatr Radiol; 2012 Apr;42(4):440-8
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  • MRI features were evaluated using a literature-based score, comprising synovial hypertrophy, cartilage lesions, bone erosions, bone marrow changes, infrapatellar fat pad heterogeneity, effusion, tendinopathy and popliteal lymphadenopathy.
  • Synovial hypertrophy was more frequent in group 1 (36.2%), but was also seen in 19.4% of the knees in group 2.
  • Signs differing among children with active and inactive disease include infrapatellar fat pad heterogeneity and synovial hypertrophy.
  • [MeSH-major] Arthritis, Juvenile / diagnosis. Knee Joint / pathology. Magnetic Resonance Imaging / methods


19. |||....... 27%  Iagnocco A, Vavala C, Vasile M, Stefanantoni K, Valesini G, Riccieri V: Power Doppler ultrasound of the hand and wrist joints in systemic sclerosis. Clin Exp Rheumatol; 2013 Mar-Apr;31(2 Suppl 76):89-95
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  • Each joint was evaluated for the presence of effusion, synovial hypertrophy, hyperaemia, bone erosions and cortical irregularities; in addition, local tendons for tenosynovitis and hyperaemia, and median nerve for entrapment neuropathy were examined.
  • RESULTS: Synovial hypertrophy was detected in 3% hand joints and in 46% wrists of SSc patients, with significant differences respect to controls (p=0.000004 and 0.000001, respectively).
  • Tenosynovitis was found in 6% out of the 1.196 synovial tendon sites examined of SSc patients with significant differences compared to healthy subjects (p=0.000001); PD resulted to be positive in 29% of them, with significantly differences compared to controls (p=0.0038).

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  • (PMID = 23190799.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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20. |||....... 27%  Maclachlan J, Gough-Palmer A, Hargunani R, Farrant J, Holloway B: Haemophilia imaging: a review. Skeletal Radiol; 2009 Oct;38(10):949-57
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  • The main imaging features of haemophilic arthropathy are described, including synovial hypertrophy, haemosiderin deposition, sub-chondral cyst formation and loss of joint space.
  • [MeSH-major] Bone Diseases / diagnosis. Bone Diseases / etiology. Diagnostic Imaging / methods. Hemophilia A / complications. Hemophilia A / diagnosis. Muscular Diseases / diagnosis. Muscular Diseases / etiology


21. |||....... 27%  Gutierrez M, Filippucci E, Salaffi F, Di Geso L, Grassi W: Differential diagnosis between rheumatoid arthritis and psoriatic arthritis: the value of ultrasound findings at metacarpophalangeal joints level. Ann Rheum Dis; 2011 Jun;70(6):1111-4
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  • [Title] Differential diagnosis between rheumatoid arthritis and psoriatic arthritis: the value of ultrasound findings at metacarpophalangeal joints level.
  • OBJECTIVE: To investigate the potential of ultrasound (US) in the differential diagnosis between rheumatoid arthritis (RA) and psoriatic arthritis (PsA) at metacarpophalangeal (MCP) joints level.
  • All US examinations were performed by two rheumatologists investigating: presence of joint cavity widening (JCW), synovial fluid and/or synovial hypertrophy, peritenon extensor tendon inflammation (PTI) and intra-articular or peri-tendinous power Doppler (PD) signal.
  • 15 of 83 (18%) MCP joints showed synovial fluid, whereas 68 of 83 (82%) MCP joints showed synovial hypertrophy.
  • 6 of 28 (21.4%) MCP joints presented synovial fluid, whereas 22 of 28 (78.5%) MCP joints showed synovial hypertrophy.
  • CONCLUSIONS: Preliminary results demonstrate that PTI pattern is a higher characteristic of PsA, which suggests a potential role of US in the differential diagnosis between RA and PsA at MCP joints level.
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Ultrasonography, Doppler / methods


22. |||....... 27%  Yalçin N, Bektaşer B, Ciçekli O, Uğraş S, Doğan M: An unusual cause of recurrent joint effusions: nonhemophilic hemosiderotic synovitis of the knee. Acta Orthop Traumatol Turc; 2010;44(2):162-5
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  • Magnetic resonance imaging showed synovial hypertrophy and grade 2 degeneration in the medial meniscus.
  • During diagnostic and surgical arthroscopy, rust-colored synovial hypertrophy was noted in the suprapatellar pouch accompanied by patchy villi and nodules and cystic changes.
  • The gross appearance of the synovium mimicked that of pigmented villonodular synovitis.
  • Biopsy specimens were obtained from different parts of the synovium and a subtotal synovectomy was performed.
  • The histopathologic diagnosis was reported as hemosiderotic synovitis.
  • [MeSH-minor] Female. Hemosiderin / analysis. Humans. Magnetic Resonance Imaging. Menisci, Tibial / pathology. Synovial Membrane / pathology. Synovial Membrane / surgery. Young Adult

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  • (PMID = 20676020.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
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23. |||....... 27%  Terslev L, D'Agostino MA, Brossard M, Aegerter P, Balint P, Backhaus M, Bruyn GA, Chary-Valckenare I, Filippucci E, Freeston J, Gandjbakhch F, Iagnocco A, Jousse-Joulin S, Mandl P, Möller I, Naredo E, Szkudlarek M, Wakefield RJ, Zayat A, Schmidt WA: Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study. Ultraschall Med; 2012 Dec;33(7):E173-8
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  • [Title] Which knee and probe position determines the final diagnosis of knee inflammation by ultrasound? Results from a European multicenter study.
  • PURPOSE: To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion.
  • The presence of synovial effusion (SE), the effusion measured in millimeters and the presence of synovial hypertrophy (SH) was noted.
  • The detection of SH is more sensitive and specific than the detection of SE, independently of the knee and probe position, for the final diagnosis of abnormality.
  • The detection of both synovial hypertrophy and effusion in the knee in neutral position (0°) with quadriceps contraction and with the probe in the midline position, are the best independent predictors for knee abnormalities.
  • [MeSH-major] Arthritis / ultrasonography. Arthritis, Rheumatoid / ultrasonography. Osteoarthritis, Knee / ultrasonography. Patient Positioning. Synovial Fluid / ultrasonography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Hypertrophy. Knee Joint / ultrasonography. Male. Middle Aged. Patella / ultrasonography. Range of Motion, Articular / physiology. Reference Values. Sensitivity and Specificity. Synovial Membrane / pathology. Synovial Membrane / ultrasonography. Young Adult

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 22194046.001).
  • [ISSN] 1438-8782
  • [Journal-full-title] Ultraschall in der Medizin (Stuttgart, Germany : 1980)
  • [ISO-abbreviation] Ultraschall Med
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
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24. |||....... 26%  Tahasildar N, Sudesh P, Tripathy SK, Shashidhar BK: Bilateral pathological dislocation of the hip secondary to tuberculous arthritis following disseminated tuberculosis: a case report and review of the literature. J Pediatr Orthop B; 2012 Nov;21(6):567-73
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  • Several pathomechanisms including capsular laxity, synovial hypertrophy, and acetabular and proximal femur destruction have been described.


25. |||....... 26%  Bello S, Bonali C, Serafino L, Di Giuseppe P, Minosi A, Terlizzi N: [Intra-articular therapy with infliximab in psoriatic arthritis: efficacy and safety in refractory monoarthritis]. Reumatismo; 2010 Jan-Mar;62(1):46-50
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  • Before the IFX injection an amount of synovial fluid was aspired from the inflamed site and the anti-TNF injection was echographic guided.
  • RESULTS: At follow-up visit after 7 days, in all patients treated with the first injection was detected total regression of the inflammation and no new inflamed synovial fluid was observed; power doppler examination shows reduction of local vascularization.
  • In 2 patients with knee arthritis and important synovial hypertrophy good results obtained after the first injection were not maintained afterwards and second injection was ineffective: these patients were evaluated for surgical intervention.
  • The efficacy in short term was observed in all cases; our supposition is that presence of synovial hypertrophy is cause of worsening.


26. |||....... 26%  Hendry GJ, Gardner-Medwin J, Steultjens MP, Woodburn J, Sturrock RD, Turner DE: Frequent discordance between clinical and musculoskeletal ultrasound examinations of foot disease in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken); 2012 Mar;64(3):441-7
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  • The same sites were examined independently by a sonographer for effusion, synovial hypertrophy, power Doppler (PD) signal, tenosynovitis, or abnormal tendon thickening.
  • US-detected effusions, synovial hypertrophy, and PD signal were recorded in 88 (12.2%), 47 (6.5%), and 12 joints (1.7%), respectively.
  • [MeSH-major] Arthritis, Juvenile / diagnosis. Foot Diseases / diagnosis. Joints / ultrasonography

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  • [Copyright] Copyright © 2012 by the American College of Rheumatology.
  • (PMID = 21972178.001).
  • [ISSN] 2151-4658
  • [Journal-full-title] Arthritis care & research
  • [ISO-abbreviation] Arthritis Care Res (Hoboken)
  • [Language] eng
  • [Grant] United Kingdom / Arthritis Research UK / / 06/S0703129
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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27. |||....... 26%  Doria AS: State-of-the-art imaging techniques for the evaluation of haemophilic arthropathy: present and future. Haemophilia; 2010 Jul;16 Suppl 5:107-14
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  • SUMMARY: In spite of the fact that the diagnosis of haemophilia is essentially clinical and laboratory-based, imaging has become an important tool for the evaluation of complications, diagnostic confirmation and/or complementation and therapeutic follow-up in haemophilic arthropathy.
  • Radiography remains the workforce horse in the diagnosis and follow-up of haemophilic arthropathy.
  • One of these advantages is its ability of differentiating synovium hypertrophy and hemosiderin deposition, which is not possible with MRI given the presence of susceptibility artefacts from extracellular hemosiderin on gradient-echo MR images.
  • [MeSH-major] Cartilage / pathology. Diagnostic Imaging / history. Hemarthrosis / diagnosis. Hemophilia A / diagnosis. Joints / pathology. Magnetic Resonance Imaging / methods

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  • (PMID = 20590865.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radioisotopes
  • [Number-of-references] 62
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28. |||....... 26%  Iagnocco A, Filippucci E, Riente L, Meenagh G, Delle Sedie A, Sakellariu G, Ceccarelli F, Montecucco C, Bombardieri S, Grassi W, Valesini G: Ultrasound imaging for the rheumatologist XLI. Sonographic assessment of the hip in OA patients. Clin Exp Rheumatol; 2012 Sep-Oct;30(5):652-7
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  • US study included the assessment of both inflammatory and structural abnormalities at the level of hip joint (joint effusion, synovial hypertrophy, local pathologic vascularisation at PD, osteophytes) and periarticular soft tissues (iliopsoas bursitis, trochanteric bursitis, iliopsoas tendinopathy, gluteus medius tendinopathy and gluteus minimus tendinopathy).
  • US detected effusion in 50% of the joints, synovial hypertrophy in 41.3%, PD signal in 0.7%, osteophytes in 77.3%; at periarticular level, trochanteric bursitis was found in 24.7% of patients, gluteus tendinopathy in 22.7%, iliopsoas tendinopathy in 7.3% and finally iliopsoas bursitis in 1.3%.
  • [MeSH-minor] Aged. Arthralgia / diagnosis. Arthralgia / etiology. Asymptomatic Diseases. Chi-Square Distribution. Female. Humans. Italy. Male. Middle Aged. Pain Measurement. Predictive Value of Tests. Prognosis. Severity of Illness Index

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  • (PMID = 23075672.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Italy
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29. |||....... 26%  Bowen CJ, Edwards CJ, Hooper L, Dewbury K, Sampson M, Sawyer S, Burridge J, Arden NK: Improvement in symptoms and signs in the forefoot of patients with rheumatoid arthritis treated with anti-TNF therapy. J Foot Ankle Res; 2010;3:10
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  • METHODS: Consecutive RA patients starting anti-TNF therapy (infliximab, etanercept, adalimumab) were assessed for presence of synovial hypertrophy and synovitis in the 2nd and 5th metatarso-phalangeal (MTP) joints and plantar forefoot bursal hypertrophy before and 12 weeks after therapy.
  • Significant differences after therapy were found for Erythrocyte Sedimentation Rate (t = 4.014, p < 0.001), C-reactive protein (t = 3.889, p = 0.001), 28 joint Disease Activity Score (t = 3.712, p = 0.0001), Visual Analog Scale (t = 2.735, p = 0.011) and Manchester Foot Pain and Disability Index (t = 3.712, p = 0.001).Presence of MTP joint synovial hypertrophy on US was noted in 67.5% of joints at baseline and 54.8% of joints at twelve weeks.
  • Presence of plantar forefoot bursal hypertrophy on US was noted in 83.3% of feet at baseline and 75% at twelve weeks.

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  • (PMID = 20565792.001).
  • [ISSN] 1757-1146
  • [Journal-full-title] Journal of foot and ankle research
  • [ISO-abbreviation] J Foot Ankle Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2901324
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30. |||....... 26%  Muça-Perja M, Riva S, Grochowska B, Mangiafico L, Mago D, Gringeri A: Ultrasonography of haemophilic arthropathy. Haemophilia; 2012 May;18(3):364-8
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  • To assess the joint status and the role of ultrasonography in routine diagnosis and monitoring of joint disease in cohort haemophilic patients.
  • Findings of patients with haemophilia, who routinely underwent ultrasonography were retrospectively evaluated to assess their joint status and the role of ultrasonography in routine diagnosis and monitoring of joint disease.
  • Synovial hypertrophy and cartilage abnormalities were the most frequent observations (88% and 76% in affected knees, respectively).

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  • [Copyright] © 2011 Blackwell Publishing Ltd.
  • (PMID = 21999202.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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31. |||....... 26%  Nemcić T, Perić P: [Ultrasonography of the hip, knee and ankle]. Reumatizam; 2010;57(2):81-9
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  • The most often US findings in inflammatory rheumatic diseases are intra-articular effusion (pathologic finding>2 mm), hypertrophy ofsynovial membrane, cartilage damage and bone erosions.
  • US characteristics ofosteoarthritis (OA) are small amount of effusion, lost of cartilage, osteophytes on the articular edges and possible mild hypertrophy of synovial membrane.
  • Recently, US has been used in diagnostics of many knee disorders, including lesions of articular cartilage, tendons, ligaments, menisci, synovial joint and surrounding blood vessels and muscles.
  • Numerous arthropathies that affect the knee could be evaluated by US too, so it is possible to document the presence of effusion, hypertrophy ofsynovial membrane, formation ofpannus, popliteal cysts, loose bodies, cartilage thinness and synovial plica.

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  • (PMID = 21875009.001).
  • [ISSN] 0374-1338
  • [Journal-full-title] Reumatizam
  • [ISO-abbreviation] Reumatizam
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Croatia
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32. |||....... 26%  Di Minno MN, Iervolino S, Soscia E, Tosetto A, Coppola A, Schiavulli M, Marrone E, Ruosi C, Salvatore M, Di Minno G: Magnetic resonance imaging and ultrasound evaluation of "healthy" joints in young subjects with severe haemophilia A. Haemophilia; 2013 May;19(3):e167-73
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  • Taking into account only moderate/severe alterations, joint effusion was found in 55% of HA and in 5% of no-HA joints (P < 0.001); synovial hypertrophy was found in 20% of HA and in none of the no-HA joints; cartilage erosion was found in 30% of HA and in none of no-HA joints.
  • MRI and US data significantly correlated as to effusion (r = 0.819, P = 0.002), synovial hypertrophy (r = 0.633, P = 0.036) and cartilage erosion (r = 0.734, P = 0.010).

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  • [Copyright] © 2013 Blackwell Publishing Ltd.
  • (PMID = 23496145.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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33. |||....... 26%  Zhang W, Dai SM: Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. Int Immunopharmacol; 2012 Sep;14(1):27-31
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  • Preclinical studies show that TGP/paeoniflorin is able to diminish pain, joint swelling, synovial hypertrophy, and the severity of bone erosion and cartilage degradation in experimental arthritis.
  • [MeSH-minor] Animals. Bone and Bones / drug effects. Bone and Bones / immunology. Clinical Trials as Topic. Drugs, Chinese Herbal / therapeutic use. Humans. Inflammation Mediators / metabolism. Lymphocyte Activation / drug effects. Medicine, Chinese Traditional. Oxidative Stress / drug effects. Synovial Membrane / drug effects. Synovial Membrane / immunology

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  • [Copyright] Copyright © 2012 Elsevier B.V. All rights reserved.
  • (PMID = 22705050.001).
  • [ISSN] 1878-1705
  • [Journal-full-title] International immunopharmacology
  • [ISO-abbreviation] Int. Immunopharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Benzoates; 0 / Bridged Compounds; 0 / Drugs, Chinese Herbal; 0 / Glucosides; 0 / Inflammation Mediators; 23180-57-6 / peoniflorin
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34. |||....... 26%  Solivetti FM, Elia F, Teoli M, De Mutiis C, Chimenti S, Berardesca E, Di Carlo A: Role of contrast-enhanced ultrasound in early diagnosis of psoriatic arthritis. Dermatology; 2010;220(1):25-31
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  • [Title] Role of contrast-enhanced ultrasound in early diagnosis of psoriatic arthritis.
  • BACKGROUND: Radiographic examination (Rx) is still the best method to obtain an accurate diagnosis of psoriatic arthritis (PsA).
  • The sensitivity and specificity of a scan can be determined by contrast enhancement in the diagnosis of arthritis during PsA in comparison with basal US with MRI.
  • The parameters evaluated by basal US were effusion, synovial hypertrophy, positiveness to color power Doppler signals and bone erosion.
  • RESULTS: Contrast-enhanced US (CEUS) seems to amplify small alterations previously detected by US and, moreover, increases the diagnostic confidence in cases of suspected symptomatology with a negative diagnosis.
  • [MeSH-minor] Adult. Aged. Early Diagnosis. Female. Humans. Italy. Joints / ultrasonography. Magnetic Resonance Imaging / methods. Male. Middle Aged. Sensitivity and Specificity. Synovitis / diagnosis


35. |||....... 26%  Riente L, Delle Sedie A, Filippucci E, Iagnocco A, Sakellariou G, Talarico R, Carli L, Di Geso L, Ceccarelli F, Bombardieri S: Ultrasound imaging for the rheumatologist XLV. Ultrasound of the shoulder in psoriatic arthritis. Clin Exp Rheumatol; 2013 May-Jun;31(3):329-33
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  • The subacromial/subdeltoid bursa, the sheath of the long biceps tendon, the glenohumeral joint and the acromion-clavicular joint were examined for the presence of synovial effusions and synovial hypertrophy.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bursa, Synovial / ultrasonography. Calcinosis / ultrasonography. Cohort Studies. Female. Humans. Male. Middle Aged. Tendinopathy / ultrasonography. Tendons / ultrasonography. Young Adult


36. |||....... 26%  Mancarella L, Magnani M, Addimanda O, Pignotti E, Galletti S, Meliconi R: Ultrasound-detected synovitis with power Doppler signal is associated with severe radiographic damage and reduced cartilage thickness in hand osteoarthritis. Osteoarthritis Cartilage; 2010 Oct;18(10):1263-8
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  • US-detected features were: synovial hypertrophy, effusion, power Doppler signal (PDS), cartilage thickness.

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  • [Copyright] Copyright © 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20656045.001).
  • [ISSN] 1522-9653
  • [Journal-full-title] Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
  • [ISO-abbreviation] Osteoarthr. Cartil.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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37. |||....... 26%  Wenham CY, Conaghan PG: Imaging the painful osteoarthritic knee joint: what have we learned? Nat Clin Pract Rheumatol; 2009 Mar;5(3):149-58
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  • In large cohort studies, synovial hypertrophy, synovial effusions, and abnormalities in the subchondral bone have been associated with knee pain.

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  • (PMID = 19252520.001).
  • [ISSN] 1745-8390
  • [Journal-full-title] Nature clinical practice. Rheumatology
  • [ISO-abbreviation] Nat Clin Pract Rheumatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 83
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38. |||....... 26%  Nestorova R, Vlad V, Petranova T, Porta F, Radunovic G, Micu MC, Iagnocco A: Ultrasonography of the hip. Med Ultrason; 2012 Sep;14(3):217-24
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  • This technique allows evaluation of different anatomical structures and their pathological changes, such as joint recess (joint effusion, synovial hypertrophy), changes within the bursae (bursitis), tendons and muscles (tendinopathy, ruptures, calcifications), as well as changes in the bony profile of the joint surfaces, ischial tuberosity, and greater trochanter (erosions, osteophytes, calcific deposits).
  • The needle aspiration of synovial fluid and steroid injections are commonly-applied activities in daily rheumatology practice.
  • [MeSH-minor] Bursa, Synovial / ultrasonography. Bursitis / ultrasonography. Fascia Lata / ultrasonography. Femoral Artery / ultrasonography. Femoral Nerve / ultrasonography. Femoral Vein / ultrasonography. Humans. Injections, Intra-Articular / methods. Muscle, Skeletal / ultrasonography. Patient Positioning. Sciatic Nerve / ultrasonography. Synovial Fluid / ultrasonography. Tendinopathy / ultrasonography. Tendon Injuries / ultrasonography. Tendons / ultrasonography. Ultrasonography, Doppler. Ultrasonography, Interventional

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  • (PMID = 22957327.001).
  • [ISSN] 2066-8643
  • [Journal-full-title] Medical ultrasonography
  • [ISO-abbreviation] Med Ultrason
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Romania
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39. |||....... 26%  Riente L, Delle Sedie A, Filippucci E, Scirè CA, Iagnocco A, Gutierrez M, Possemato N, Meenagh G, Valesini G, Montecucco C, Grassi W, Bombardieri S: Ultrasound Imaging for the rheumatologist XXVII. Sonographic assessment of the knee in patients with rheumatoid arthritis. Clin Exp Rheumatol; 2010 May-Jun;28(3):300-3
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  • Bilateral US examination of the knee was performed to visualise the presence of effusion, synovial proliferation, bone erosions, femoral cartilage abnormalities, quadricipital and/or patellar enthesopathy.
  • Synovial hypertrophy was present in 115 out of 140 (82%) knees associated with effusion and in 22 out of 115 (19%) knees intra-articular power Doppler (PD) signal was found.


40. |||....... 26%  Balsa A, de Miguel E, Castillo C, Peiteado D, Martín-Mola E: Superiority of SDAI over DAS-28 in assessment of remission in rheumatoid arthritis patients using power Doppler ultrasonography as a gold standard. Rheumatology (Oxford); 2010 Apr;49(4):683-90
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  • RESULTS: Synovial hypertrophy (SH) and PD were present in 92 (94.8%) and 41 (42.3%) patients.


41. |||....... 26%  Chang EY, McAnally JL, Van Horne JR, Statum S, Wolfson T, Gamst A, Chung CB: Metal-on-metal total hip arthroplasty: do symptoms correlate with MR imaging findings? Radiology; 2012 Dec;265(3):848-57
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  • Two observers retrospectively reviewed the images for the presence and size of pseudotumor, communication with the pseudocapsule, wall thickness, synovial hypertrophy, compartmentalization, solid components, foci of wall susceptibility, osteolysis, bone marrow edema, abductor muscle or tendon abnormality, and Anderson MR grade (normal, infection, or varying severity of metal-on-metal disease).
  • [MeSH-major] Arthroplasty, Replacement, Hip. Hip Prosthesis. Magnetic Resonance Imaging / methods. Metals. Postoperative Complications / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disability Evaluation. Female. Humans. Male. Middle Aged. Pain, Postoperative / diagnosis. Pain, Postoperative / epidemiology. Prevalence. Prosthesis Failure. Retrospective Studies. Statistics, Nonparametric


42. |||....... 26%  Scirè CA, Iagnocco A, Meenagh G, Riente L, Filippucci E, Delle Sedie A, Codullo V, Grassi W, Bombardieri S, Valesini G, Montecucco C: Ultrasound imaging for the rheumatologist. XXVIII. Impact of sonographic knee joint involvement in recent-onset inflammatory polyarthritis. Clin Exp Rheumatol; 2010 Jul-Aug;28(4):449-53
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  • Joint group involvement was defined when at least one joint showed intra-articular signs of inflammation (synovial fluid abnormalities and/or synovial hypertrophy), according to the OMERACT definitions.
  • [MeSH-minor] Aged. Cohort Studies. Cross-Sectional Studies. Diagnosis, Differential. Disability Evaluation. Female. Health Surveys. Humans. Male. Middle Aged. Outcome Assessment (Health Care). Severity of Illness Index

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  • (PMID = 20810032.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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43. |||....... 26%  Melchiorre D, Linari S, Innocenti M, Biscoglio I, Toigo M, Cerinic MM, Morfini M: Ultrasound detects joint damage and bleeding in haemophilic arthropathy: a proposal of a score. Haemophilia; 2011 Jan;17(1):112-7
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  • The joints of 62 patients (pts) with haemophilia A or haemophilia B were consecutively evaluated and scored (score ranging from 0 to 21) for effusion (E), bone remodelling (BR), cartilage damage (CD), synovial hypertrophy (SH), haemosiderin (H), osteophytes (O), haemarthrosis (Hae), erosion (Er) and fibrotic septa (FS) with US.
  • US showed effusion in 57 joint, bone remodelling in 62, cartilage damage in 64, synovial hypertrophy in 45, haemosiderin in 39, osteophytes in 30, haemarthrosis in 24, erosion in 5 and fibrotic septa in 3.

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 21070482.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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44. |||....... 26%  Yu W, Lin Q, Guermazi A, Yu X, Shang W, Zhu H, Meng W, Xu R, Zhao Y: Comparison of radiography, CT and MR imaging in detection of arthropathies in patients with haemophilia. Haemophilia; 2009 Sep;15(5):1090-6
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  • Findings of soft tissue swelling, osteoporosis, epiphyseal overgrowth, joint erosion, cysts, joint space narrowing, bone marrow oedema, joint effusion, haemorrhage, synovial hypertrophy and widened intercondylar notches as well as anterior and posterior cruciate ligaments (for the knee) were used in all imaging comparisons.
  • Bone marrow oedema in 14 joints, haemorrhage in 34 joints and synovial hypertrophy in 27 joints were seen on MR images, but not on CT or radiography.

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  • (PMID = 19515027.001).
  • [ISSN] 1365-2516
  • [Journal-full-title] Haemophilia : the official journal of the World Federation of Hemophilia
  • [ISO-abbreviation] Haemophilia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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45. |||....... 26%  Alessi S, Depaoli R, Canepari M, Bartolucci F, Zacchino M, Draghi F: Baker's cyst in pediatric patients: Ultrasonographic characteristics. J Ultrasound; 2012 Feb;15(1):76-81
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  • MATERIALS AND METHODS: We examined 16 pediatric patients, with the clinical diagnosis of Baker's cyst.
  • The idiopathic forms (6) exhibited anechoic structure; in patients with arthritis (3) there was hypertrophic synovium; in hemophilic patients at the presentation (2) anechoic structure with layering (serum and red blood cells); in chronic hemophilia synovial hypertrophy was seen.

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  • (PMID = 23396996.001).
  • [ISSN] 1971-3495
  • [Journal-full-title] Journal of ultrasound
  • [ISO-abbreviation] J Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3558073
  • [Keywords] NOTNLM ; Arthritis / Baker’s cysts / Children / Juvenile arthritis / Sonography
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46. |||....... 26%  Iagnocco A, Perricone C, Scirocco C, Ceccarelli F, Modesti M, Gattamelata A, Vavala C, Rutigliano IM, Musetescu A, Valesini G: The interobserver reliability of ultrasound in knee osteoarthritis. Rheumatology (Oxford); 2012 Nov;51(11):2013-9
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  • US examinations were conducted with independent blinded evaluations of inflammatory (joint effusion, synovial hypertrophy, power Doppler signal, Baker's cysts) and structural (osteophytes, cortical bone irregularities, femoral hyaline cartilage abnormalities, protrusion of the medial meniscus) lesions.


47. |||....... 26%  Delle Sedie A, Riente L, Filippucci E, Scirè CA, Iagnocco A, Gutierrez M, Valesini G, Montecucco C, Grassi W, Bombardieri S: Ultrasound imaging for the rheumatologist XXVI. Sonographic assessment of the knee in patients with psoriatic arthritis. Clin Exp Rheumatol; 2010 Mar-Apr;28(2):147-52
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  • In the 59% of the patients we noticed synovial hypertrophy.
  • [MeSH-minor] Adult. Aged. Female. Humans. Hypertrophy. Male. Middle Aged. Popliteal Cyst / pathology. Popliteal Cyst / ultrasonography. Synovitis / pathology. Synovitis / ultrasonography


48. |||....... 26%  Tormenta S, Sconfienza LM, Iannessi F, Bizzi E, Massafra U, Orlandi D, Migliore A: Prevalence study of iliopsoas bursitis in a cohort of 860 patients affected by symptomatic hip osteoarthritis. Ultrasound Med Biol; 2012 Aug;38(8):1352-6
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  • Two radiologists evaluated the presence of IB, joint effusion, synovial hypertrophy, communication between bursa and articular space.
  • Effusion was present in 9/19 patients, hypertrophy in 6/19 and communication in 9/19.
  • In patients with no IB, effusion was detected in 27/860 and hypertrophy in 25/860 (p < 0.001 compared with IB patients).

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  • [Copyright] Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
  • (PMID = 22698514.001).
  • [ISSN] 1879-291X
  • [Journal-full-title] Ultrasound in medicine & biology
  • [ISO-abbreviation] Ultrasound Med Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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49. |||....... 26%  Iagnocco A, Filippucci E, Riente L, Meenagh G, Delle Sedie A, Sakellariou G, Ceccarelli F, Montecucco C, Bombardieri S, Grassi W, Valesini G: Ultrasound imaging for the rheumatologist XXXV. Sonographic assessment of the foot in patients with osteoarthritis. Clin Exp Rheumatol; 2011 Sep-Oct;29(5):757-62
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  • US study included the assessment of both inflammatory (joint effusion, synovial hypertrophy, local pathologic vascularisation at PD, big-toe bursitis) and structural (osteophytes, MTP joints subluxation) abnormalities.

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  • (PMID = 22041178.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study
  • [Publication-country] Italy
  •  go-up   go-down


50. |||....... 26%  Ingegnoli F, Soldi A, Meroni PL: Power Doppler sonography and clinical monitoring for hyaluronic Acid treatment of rhizarthrosis: a pilot study. J Hand Microsurg; 2011 Dec;3(2):51-4
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  • No significant decrease in the synovial hypertrophy score was observed during the study.

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  • (PMID = 23204768.001).
  • [ISSN] 0974-6897
  • [Journal-full-title] Journal of hand and microsurgery
  • [ISO-abbreviation] J Hand Microsurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3172359
  • [Keywords] NOTNLM ; Hyaluronic acid / Rhizarthrosis / Ultrasonography
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